FI106460B - Bisykliset beta-laktaami/parabeenikompleksit ja menetelmä beta-laktaamijohdannaisten valmistamiseksi - Google Patents
Bisykliset beta-laktaami/parabeenikompleksit ja menetelmä beta-laktaamijohdannaisten valmistamiseksi Download PDFInfo
- Publication number
- FI106460B FI106460B FI943081A FI943081A FI106460B FI 106460 B FI106460 B FI 106460B FI 943081 A FI943081 A FI 943081A FI 943081 A FI943081 A FI 943081A FI 106460 B FI106460 B FI 106460B
- Authority
- FI
- Finland
- Prior art keywords
- loracarbef
- lactam
- paraben
- methylparaben
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cephalosporin Compounds (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8465193 | 1993-06-28 | ||
| US08/084,651 US5412094A (en) | 1993-06-28 | 1993-06-28 | Bicyclic beta-lactam/paraben complexes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI943081A0 FI943081A0 (fi) | 1994-06-27 |
| FI943081A FI943081A (fi) | 1994-12-29 |
| FI106460B true FI106460B (fi) | 2001-02-15 |
Family
ID=22186328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI943081A FI106460B (fi) | 1993-06-28 | 1994-06-27 | Bisykliset beta-laktaami/parabeenikompleksit ja menetelmä beta-laktaamijohdannaisten valmistamiseksi |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5412094A (es) |
| EP (1) | EP0637587B1 (es) |
| JP (1) | JPH0748383A (es) |
| KR (1) | KR950000707A (es) |
| CN (1) | CN1044246C (es) |
| AT (1) | ATE159942T1 (es) |
| AU (1) | AU674226B2 (es) |
| BR (1) | BR9402561A (es) |
| CA (1) | CA2126401A1 (es) |
| CO (1) | CO4230098A1 (es) |
| CZ (1) | CZ285452B6 (es) |
| DE (1) | DE69406607T2 (es) |
| DK (1) | DK0637587T3 (es) |
| ES (1) | ES2110185T3 (es) |
| FI (1) | FI106460B (es) |
| GR (1) | GR3025563T3 (es) |
| HU (1) | HU219484B (es) |
| IL (1) | IL110103A (es) |
| NO (1) | NO305480B1 (es) |
| NZ (1) | NZ260791A (es) |
| PE (1) | PE57294A1 (es) |
| PL (1) | PL177317B1 (es) |
| RU (1) | RU2134265C1 (es) |
| YU (1) | YU40694A (es) |
| ZA (1) | ZA944376B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5550231A (en) * | 1993-06-15 | 1996-08-27 | Eli Lilly And Company | Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof |
| US6001996A (en) * | 1995-05-11 | 1999-12-14 | Eli Lilly And Company | Complexes of cephalosporins and carbacephalosporins with parabens |
| US20090088443A1 (en) * | 2002-02-15 | 2009-04-02 | Julius Remenar | Novel crystalline forms of conazoles and methods of making and using the same |
| US20100311701A1 (en) * | 2002-02-15 | 2010-12-09 | Transform Pharmaceuticals, Inc | Pharmaceutical Co-Crystal Compositions |
| US7790905B2 (en) * | 2002-02-15 | 2010-09-07 | Mcneil-Ppc, Inc. | Pharmaceutical propylene glycol solvate compositions |
| US7927613B2 (en) | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
| CA2477923C (en) * | 2002-03-01 | 2021-02-23 | University Of South Florida | Multiple-component solid phases containing at least one active pharmaceutical ingredient |
| US20070059356A1 (en) * | 2002-05-31 | 2007-03-15 | Almarsson Oern | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
| MXPA05000232A (es) * | 2002-06-21 | 2005-06-17 | Transform Pharmaceuticals Inc | Composiciones farmaceuticas con disolucion mejorada. |
| US8183290B2 (en) * | 2002-12-30 | 2012-05-22 | Mcneil-Ppc, Inc. | Pharmaceutically acceptable propylene glycol solvate of naproxen |
| JP2013510113A (ja) * | 2009-11-06 | 2013-03-21 | ビーエーエスエフ ソシエタス・ヨーロピア | ４−ヒドロキシ安息香酸及び選択された殺有害生物剤の結晶複合体 |
| CN105997931A (zh) * | 2016-07-19 | 2016-10-12 | 南京正宽医药科技有限公司 | 一种头孢克肟胶囊及其制备方法 |
| CN113845529B (zh) * | 2021-10-15 | 2024-02-27 | 东南大学 | 一种头孢氨苄共晶化合物及其制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3531481A (en) * | 1969-04-21 | 1970-09-29 | Lilly Co Eli | Method for manufacture of crystalline cephalosporin |
| GB1510794A (en) * | 1974-08-06 | 1978-05-17 | Univ Kingston | 1-oxacephems and intermediates therefor |
| AT363594B (de) * | 1978-02-01 | 1981-08-10 | Biochemie Gmbh | Verfahren zur herstellung eines neuen formamidkomplexes von 7-beta-(d-2-amino-2-phenylacetamido)-3-methylceph-3-emcarbonsaeure |
| PH21016A (en) * | 1982-07-23 | 1987-06-30 | Meiji Seika Kaisha | 2-alkyl-1-oxa-dethia-cephalosporin derivatives and process for producing said compound |
| US4782144A (en) * | 1987-09-14 | 1988-11-01 | Eli Lilly And Company | 1-carba(dethia)-3-hydroxy-3-cephem ester crystalline and crystalline solvate thereof |
| EG18529A (en) * | 1987-10-06 | 1993-04-30 | Lilly Co Eli | Process for preparing b-lactam hydrate |
| EP0341991A3 (en) * | 1988-05-13 | 1991-08-28 | Eli Lilly And Company | Method for recovery of antibiotics from mother liquors and novel pharmaceutically-acceptable salts thereof |
| CA2002596A1 (en) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates of b-lactam antibiotic |
| US4977257A (en) * | 1988-11-14 | 1990-12-11 | Eli Lilly And Company | DMF solvates of a β-lactam antibiotic |
| US5142042A (en) * | 1989-01-23 | 1992-08-25 | Purzer Pharmaceutical Co., Ltd. | Process for preparing well crystallized alkali metal salts of 3, 7-substituted 7-aminocephalosporanic acid derivatives |
-
1993
- 1993-06-28 US US08/084,651 patent/US5412094A/en not_active Expired - Fee Related
-
1994
- 1994-06-20 DK DK94304442.0T patent/DK0637587T3/da active
- 1994-06-20 PE PE1994244825A patent/PE57294A1/es not_active Application Discontinuation
- 1994-06-20 ES ES94304442T patent/ES2110185T3/es not_active Expired - Lifetime
- 1994-06-20 DE DE69406607T patent/DE69406607T2/de not_active Expired - Fee Related
- 1994-06-20 AT AT94304442T patent/ATE159942T1/de not_active IP Right Cessation
- 1994-06-20 EP EP94304442A patent/EP0637587B1/en not_active Expired - Lifetime
- 1994-06-20 ZA ZA944376A patent/ZA944376B/xx unknown
- 1994-06-20 NZ NZ260791A patent/NZ260791A/en unknown
- 1994-06-20 CZ CZ941519A patent/CZ285452B6/cs not_active IP Right Cessation
- 1994-06-21 CA CA002126401A patent/CA2126401A1/en not_active Abandoned
- 1994-06-21 NO NO942364A patent/NO305480B1/no not_active IP Right Cessation
- 1994-06-23 IL IL11010394A patent/IL110103A/xx not_active IP Right Cessation
- 1994-06-24 PL PL94303977A patent/PL177317B1/pl unknown
- 1994-06-24 CO CO94027493A patent/CO4230098A1/es unknown
- 1994-06-24 AU AU65950/94A patent/AU674226B2/en not_active Ceased
- 1994-06-25 KR KR1019940014713A patent/KR950000707A/ko active IP Right Grant
- 1994-06-27 JP JP6144637A patent/JPH0748383A/ja active Pending
- 1994-06-27 BR BR9402561A patent/BR9402561A/pt not_active Application Discontinuation
- 1994-06-27 FI FI943081A patent/FI106460B/fi active
- 1994-06-27 YU YU40694A patent/YU40694A/sh unknown
- 1994-06-27 RU RU94022484A patent/RU2134265C1/ru active
- 1994-06-27 CN CN94106572A patent/CN1044246C/zh not_active Expired - Fee Related
- 1994-06-28 HU HU9401935A patent/HU219484B/hu not_active IP Right Cessation
-
1997
- 1997-12-02 GR GR970403213T patent/GR3025563T3/el unknown
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