FI102379B1 - Uretaanisuojattuja aminohappo-N-karboksianhydridejä - Google Patents

Uretaanisuojattuja aminohappo-N-karboksianhydridejä

Info

Publication number
FI102379B1
FI102379B1 FI895382A FI895382A FI102379B1 FI 102379 B1 FI102379 B1 FI 102379B1 FI 895382 A FI895382 A FI 895382A FI 895382 A FI895382 A FI 895382A FI 102379 B1 FI102379 B1 FI 102379B1
Authority
FI
Finland
Prior art keywords
amino acid
protected amino
carboxyanhydrides
uranium
compounds
Prior art date
Application number
FI895382A
Other languages
English (en)
Swedish (sv)
Other versions
FI102379B (fi
FI895382A0 (fi
Inventor
William D Fuller
Michael Philip Cohen
Fred R Naider
Murray Goodman
Original Assignee
Bioresearch Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Inc filed Critical Bioresearch Inc
Publication of FI895382A0 publication Critical patent/FI895382A0/fi
Application granted granted Critical
Publication of FI102379B1 publication Critical patent/FI102379B1/fi
Publication of FI102379B publication Critical patent/FI102379B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • C07D263/26Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C07K1/023General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution using racemisation inhibiting agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
FI895382A 1988-03-11 1989-11-10 Uretaanisuojattuja aminohappo-N-karboksianhydridejä FI102379B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US16808788 1988-03-11
US07/168,087 US4946942A (en) 1988-03-11 1988-03-11 Urethane-protected amino acid-N-carboxyanhydrides
US8900875 1989-03-03
PCT/US1989/000875 WO1989008643A1 (en) 1988-03-11 1989-03-03 Urethane-protected amino acid-n-carboxyanhydrides

Publications (3)

Publication Number Publication Date
FI895382A0 FI895382A0 (fi) 1989-11-10
FI102379B1 true FI102379B1 (fi) 1998-11-30
FI102379B FI102379B (fi) 1998-11-30

Family

ID=22610066

Family Applications (1)

Application Number Title Priority Date Filing Date
FI895382A FI102379B (fi) 1988-03-11 1989-11-10 Uretaanisuojattuja aminohappo-N-karboksianhydridejä

Country Status (21)

Country Link
US (1) US4946942A (fi)
EP (1) EP0357750B1 (fi)
JP (1) JP2875834B2 (fi)
KR (1) KR970002229B1 (fi)
CN (1) CN1022412C (fi)
AT (1) ATE108438T1 (fi)
AU (1) AU616054B2 (fi)
CA (1) CA1321280C (fi)
CZ (1) CZ148989A3 (fi)
DD (1) DD280322A5 (fi)
DE (1) DE68916722T2 (fi)
FI (1) FI102379B (fi)
HK (1) HK1007744A1 (fi)
HU (1) HU205091B (fi)
IE (1) IE65149B1 (fi)
IL (1) IL89541A0 (fi)
NO (1) NO306304B1 (fi)
NZ (1) NZ228282A (fi)
PT (1) PT89961B (fi)
RU (1) RU2007396C1 (fi)
WO (1) WO1989008643A1 (fi)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006661A (en) * 1987-06-16 1991-04-09 University Of Cincinnati Selective stereospecific biologically active beta-lactams
DE3839379A1 (de) * 1988-11-22 1990-05-23 Hoechst Ag Verfahren zur herstellung von tripeptiden
US6406844B1 (en) 1989-06-07 2002-06-18 Affymetrix, Inc. Very large scale immobilized polymer synthesis
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5547839A (en) 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US6379895B1 (en) 1989-06-07 2002-04-30 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US6309822B1 (en) 1989-06-07 2001-10-30 Affymetrix, Inc. Method for comparing copy number of nucleic acid sequences
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US6346413B1 (en) 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
US6551784B2 (en) 1989-06-07 2003-04-22 Affymetrix Inc Method of comparing nucleic acid sequences
US6506558B1 (en) 1990-03-07 2003-01-14 Affymetrix Inc. Very large scale immobilized polymer synthesis
WO1992010588A1 (en) 1990-12-06 1992-06-25 Affymax Technologies N.V. Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
US6468740B1 (en) 1992-11-05 2002-10-22 Affymetrix, Inc. Cyclic and substituted immobilized molecular synthesis
TW306932B (fi) * 1993-08-27 1997-06-01 Holland Sweetener Co
US7378236B1 (en) 1994-06-17 2008-05-27 The Board Of Trustees Of The Leland Stanford Junior University Method for analyzing gene expression patterns
US7625697B2 (en) * 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US7323298B1 (en) 1994-06-17 2008-01-29 The Board Of Trustees Of The Leland Stanford Junior University Microarray for determining the relative abundances of polynuceotide sequences
IN184759B (fi) * 1997-07-22 2000-09-23 Kaneka Corp
PL339360A1 (en) 1998-07-21 2000-12-18 Kaneka Corp Method of crystallising n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanyl-l-proline maleate
US6545264B1 (en) 1998-10-30 2003-04-08 Affymetrix, Inc. Systems and methods for high performance scanning
SE0000382D0 (sv) 2000-02-07 2000-02-07 Astrazeneca Ab New process
CN1388804A (zh) * 2000-07-04 2003-01-01 三井化学株式会社 在氮原子上具有取代基的氨基酸-n-羧基酸酐
DE10333368B4 (de) * 2003-07-23 2008-08-28 Universität Leipzig Oberflächenfunktionalisiertes Trägermaterial, Verfahren zu dessen Herstellung und dessen Verwendungen
FR2858976B1 (fr) * 2003-08-22 2006-02-10 Isochem Sa Procede d'obtention de n-carboxyanhydrides d'alpha-aminoacides a protection urethane
WO2006047703A2 (en) * 2004-10-26 2006-05-04 Sigma-Aldrich Co. Synthesis of amino acid, n-carboxyanhydrides
NZ569756A (en) 2005-12-12 2011-07-29 Allaccem Inc Methods and systems for preparing antimicrobial films and coatings utilising polycyclic bridged ammonium salts
NZ579785A (en) 2007-02-21 2012-06-29 Allaccem Inc Bridged polycyclic compound based compositions for the inhibition and amelioration of disease
US20090035816A1 (en) * 2007-08-02 2009-02-05 Scinopharm Taiwan Ltd. Process for the preparation of a polypeptide
US8188068B2 (en) * 2007-08-10 2012-05-29 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in pets
US8153617B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in humans
US8153618B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for topical applications for pets
US20090074833A1 (en) * 2007-08-17 2009-03-19 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling bone resorption
FR2928372B1 (fr) * 2008-03-10 2010-12-31 Solvay Procede de synthese peptidique
US20100004218A1 (en) * 2008-06-20 2010-01-07 Whiteford Jeffery A Bridged polycyclic compound based compositions for renal therapy
US20100016270A1 (en) * 2008-06-20 2010-01-21 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling cholesterol levels
JP5833635B2 (ja) * 2011-03-25 2015-12-16 日本曹達株式会社 グルタミン酸ベンジルエステルn−無水カルボン酸の結晶、及びグルタミン酸ベンジルエステルn−無水カルボン酸の結晶化方法。
MX2017011820A (es) 2015-03-17 2018-03-15 Regeneron Pharma Reactivos de acilacion de aminoacidos y metodos para usar los mismos.
JP6766432B2 (ja) * 2016-04-28 2020-10-14 Jsr株式会社 ポリアミノ酸の製造方法
CA3054534A1 (en) * 2017-03-02 2018-09-07 Glytech, Inc. Method for manufacturing amino acid polymer
CN112778236A (zh) * 2019-11-08 2021-05-11 华东理工大学 β、γ-氨基酸N-羧基硫代羰基环内酸酐单体的合成、聚合反应、聚合物制备及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1173562A (en) * 1966-04-25 1969-12-10 Pierrel Spa Chloramphenicol Ester Salts, the Preparation therof and Compositions Containing them
US4267344A (en) * 1972-09-22 1981-05-12 Proteinkemisk Institut. Tilknyttet Akademiet For De Tekniske Videnskaber N-Substituted N-carboxyanhydrides of α-amino acids and their application in the preparation of peptides
US4038411A (en) * 1973-09-25 1977-07-26 Merck & Co., Inc. Antihypertensive amino acid esters
US4038282A (en) * 1975-11-26 1977-07-26 Merck & Co., Inc. Pyridyl-4-methyl-succinimidocarbonate and process for its preparation
US4367234A (en) * 1980-07-28 1983-01-04 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones

Also Published As

Publication number Publication date
WO1989008643A1 (en) 1989-09-21
CN1022412C (zh) 1993-10-13
JPH02503923A (ja) 1990-11-15
PT89961A (pt) 1989-11-10
DD280322A5 (de) 1990-07-04
JP2875834B2 (ja) 1999-03-31
NZ228282A (en) 1990-10-26
EP0357750B1 (en) 1994-07-13
CN1040793A (zh) 1990-03-28
NO306304B1 (no) 1999-10-18
ATE108438T1 (de) 1994-07-15
DE68916722T2 (de) 1994-11-03
HK1007744A1 (en) 1999-04-23
IL89541A0 (en) 1989-09-10
NO894503D0 (no) 1989-11-10
EP0357750A1 (en) 1990-03-14
IE890778L (en) 1989-09-11
DE68916722D1 (de) 1994-08-18
HUT52488A (en) 1990-07-28
NO894503L (no) 1989-11-10
CA1321280C (en) 1993-08-10
HU205091B (en) 1992-03-30
AU4188789A (en) 1989-10-05
PT89961B (pt) 1994-04-29
FI102379B (fi) 1998-11-30
AU616054B2 (en) 1991-10-17
KR900700469A (ko) 1990-08-13
RU2007396C1 (ru) 1994-02-15
CZ148989A3 (en) 1997-11-12
HU891841D0 (en) 1990-04-28
US4946942A (en) 1990-08-07
KR970002229B1 (ko) 1997-02-26
IE65149B1 (en) 1995-10-04
FI895382A0 (fi) 1989-11-10
EP0357750A4 (en) 1991-01-30

Similar Documents

Publication Publication Date Title
FI102379B1 (fi) Uretaanisuojattuja aminohappo-N-karboksianhydridejä
DE69324487T2 (de) Rezeptorbindende region des diphtherietoxius
DE68929043D1 (de) Für androgen-rezeptor-protein kodierende dna
TR199802534T2 (xx) Leptin (OB Protein) fragmanlar�
DK156592A (da) Human-h1-praeprorelaxin, -prorelaxin og -relaxin samt polypeptid med relaxinaktivitet og fremgangsmaade til sammenfoejning af a- og b-kaederne i human-h1-relaxin
NO940299L (no) Peptid med organbeskyttende aktivitet
BR9306272A (pt) Peptídeo e composiçao farmacêutica
IT1163037B (it) Procedimento di sintesi di peptidi e agenti di bloccaggio di amminoacidi
DE3685651T2 (de) Den antigenischen und immunogenischen determinanten von wichtigen neutralisierenden proteinen des rotavirus entsprechende peptide.
SE8901552D0 (sv) Acid addition salts of amidated or glycine, their preparation and use
DE68917837D1 (de) Peptid-Verbindungen.
AU3426889A (en) Synthetic peptides from streptococcal m protein and vaccines prepared therefrom
NO177859C (no) Fremgangsmåte til produksjon av angiogen faktor
SE8801723D0 (sv) Fibronectin binding protein as well as its preparation
ATE110389T1 (de) Thf-zusammensetzungen.
DE69832299D1 (de) Einkettigen polypeptiden enthalten troponin i und troponin c
ATE92078T1 (de) Pharmakologisch aktive peptide.
ATE46173T1 (de) Pharmakologisch aktive peptide.
FI961398A (fi) Menetelmä terapeuttisesti käyttökelpoisen peptidin valmistamiseksi
SE8700761D0 (sv) Tillempningar av en polypeptid

Legal Events

Date Code Title Description
FG Patent granted

Owner name: BIORESEARCH, INC.