ES8706689A1 - Procedimiento para la obtencion de nuevos derivados del tieno (2,3-d) imidazol - Google Patents

Procedimiento para la obtencion de nuevos derivados del tieno (2,3-d) imidazol

Info

Publication number
ES8706689A1
ES8706689A1 ES554732A ES554732A ES8706689A1 ES 8706689 A1 ES8706689 A1 ES 8706689A1 ES 554732 A ES554732 A ES 554732A ES 554732 A ES554732 A ES 554732A ES 8706689 A1 ES8706689 A1 ES 8706689A1
Authority
ES
Spain
Prior art keywords
lower alkyl
thieno
preparation
denotes
denotes hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554732A
Other languages
English (en)
Other versions
ES554732A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patheon Austria GmbH and Co KG
Original Assignee
Chemie Linz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemie Linz AG filed Critical Chemie Linz AG
Publication of ES554732A0 publication Critical patent/ES554732A0/es
Publication of ES8706689A1 publication Critical patent/ES8706689A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Resins (AREA)

Abstract

METODO DE PREPARAR NUEVOS DERIVADOS DEL TIENO(2,3-D)IMIDAZOL. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), CON UN ALCOHOL DE BAJO PUNTO DE EBULLICION, TAL COMO METANOL, PARA OBTENER NUEVOS DERIVADOS DE TIENO(2,3-D)IMIDAZOL Y SUS SALES FARMACEUTICAMENTE ACEPTABLES DE FORMULA (I), DONDE R1 ES H, ALQUILO INFERIOR, CLORO, BROMO, ACETILO, CICLOPROPILCARBONILO O ETOXICARBONILO; R2 ES H O ALQUILO INFERIOR; R3, R5 Y R6 INDEPENDIENTEMENTE ENTRE SI, SON H O ALQUILO INFERIOR; R4 ES H O ALCOXI INFERIOR; Y N ES 0 O 1. TIENEN APLICACIONES FARMACEUTICAS PARA EL TRATAMIENTO DE ULCERAS ESTOMACALES. *FORMULA*
ES554732A 1985-05-07 1986-05-07 Procedimiento para la obtencion de nuevos derivados del tieno (2,3-d) imidazol Expired ES8706689A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT136085 1985-05-07

Publications (2)

Publication Number Publication Date
ES554732A0 ES554732A0 (es) 1987-07-01
ES8706689A1 true ES8706689A1 (es) 1987-07-01

Family

ID=3512202

Family Applications (1)

Application Number Title Priority Date Filing Date
ES554732A Expired ES8706689A1 (es) 1985-05-07 1986-05-07 Procedimiento para la obtencion de nuevos derivados del tieno (2,3-d) imidazol

Country Status (15)

Country Link
EP (1) EP0201094A3 (es)
JP (1) JPS61254591A (es)
KR (1) KR860009021A (es)
AU (1) AU582649B2 (es)
CA (1) CA1262731A (es)
CS (2) CS256397B2 (es)
DD (1) DD258608A1 (es)
DK (1) DK208086A (es)
ES (1) ES8706689A1 (es)
FI (1) FI861772A (es)
HU (1) HU194244B (es)
NO (1) NO861802L (es)
NZ (1) NZ216054A (es)
SU (1) SU1456018A3 (es)
ZA (1) ZA863354B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU580042B2 (en) * 1984-03-22 1988-12-22 Bresatec Limited Non-radioactive biological probes
ES2032394T3 (es) * 1986-02-20 1993-02-16 Hoechst Aktiengesellschaft Procedimiento para preparar derivados de tienoimidazol sustituidos.
WO1987005296A1 (en) * 1986-03-07 1987-09-11 Pfizer Inc. 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents
CA1256109A (en) * 1986-09-10 1989-06-20 Franz Rovenszky Process for the preparation of derivatives of 4, 5-dihydrooxazoles
DE3639926A1 (de) * 1986-11-22 1988-06-01 Hoechst Ag Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
DE3723327A1 (de) * 1987-07-15 1989-02-02 Hoechst Ag Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer, magenschutzmittel sowie als medikament gegen intestinale entzuendungen
AU622866B2 (en) * 1987-07-21 1992-04-30 Hoechst Aktiengesellschaft Substituted thienoimidazole derivatives, processes for their preparation, pharmaceutical formulations containing them and their use as gastric acid secretion inhibitors
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono
TNSN88083A1 (fr) * 1987-08-15 1990-07-10 Hoechst Ag Procede de preparation de nouveaux derives de thieno-imidazole substitues
DE3851133D1 (de) * 1987-11-13 1994-09-22 Hoechst Ag Substituierte Thienoimidazol-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zubereitungen und ihre Verwendung als Magensäuresekretionshemmer.
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
ES2032394T3 (es) * 1986-02-20 1993-02-16 Hoechst Aktiengesellschaft Procedimiento para preparar derivados de tienoimidazol sustituidos.
WO1987005296A1 (en) * 1986-03-07 1987-09-11 Pfizer Inc. 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents
DE3639926A1 (de) * 1986-11-22 1988-06-01 Hoechst Ag Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer

Also Published As

Publication number Publication date
EP0201094A2 (de) 1986-12-17
CS331686A2 (en) 1987-08-13
DK208086D0 (da) 1986-05-06
ZA863354B (en) 1986-12-30
NO861802L (no) 1986-11-10
FI861772A0 (fi) 1986-04-28
CS256397B2 (en) 1988-04-15
HU194244B (en) 1988-01-28
KR860009021A (ko) 1986-12-19
CS256400B2 (cs) 1988-04-15
JPS61254591A (ja) 1986-11-12
CA1262731A (en) 1989-11-07
CS670086A2 (en) 1987-08-13
HUT40667A (en) 1987-01-28
AU5716486A (en) 1986-11-13
NZ216054A (en) 1988-10-28
AU582649B2 (en) 1989-04-06
ES554732A0 (es) 1987-07-01
EP0201094A3 (de) 1988-04-27
DD258608A1 (de) 1988-07-27
DK208086A (da) 1986-11-08
FI861772A (fi) 1986-11-08
SU1456018A3 (ru) 1989-01-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203