ES2004255A6 - Procedimiento de preparar compuestos del tipo de las piracinas y analogos. - Google Patents

Procedimiento de preparar compuestos del tipo de las piracinas y analogos.

Info

Publication number
ES2004255A6
ES2004255A6 ES8700631A ES8700631A ES2004255A6 ES 2004255 A6 ES2004255 A6 ES 2004255A6 ES 8700631 A ES8700631 A ES 8700631A ES 8700631 A ES8700631 A ES 8700631A ES 2004255 A6 ES2004255 A6 ES 2004255A6
Authority
ES
Spain
Prior art keywords
pharmacologically active
pyrazines
pyrido
iii
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8700631A
Other languages
English (en)
Inventor
Leandro Baiocchi
Bruno Silvestrini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Acraf SpA
Original Assignee
Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco ACRAF SpA filed Critical Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Publication of ES2004255A6 publication Critical patent/ES2004255A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO DE PREPARAR COMPUESTOS DEL TIPO DE LAS PIRACINAS Y ANALOGOS, DE LA FORMULA III Y SUS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES, QUE COMPRENDE HACER REACCIONAR UN COMPUESTO DE LA FORMULA CH3-CHX-COOR'', DONDE X ES UN GRUPO QUE PARTE ESCOGIDO DE HALOGENO Y O-SO2-R DONDE R ES METILO, FENILO, P-METILFENILO Y TRIFENILMETILO; Y R'' ES ALQUILO C1-6 CON UN COMPUESTO DE LA FORMULA (II)DESCARGANDO LOS COMPUESTOS INSOLUBLES EN ACIDOS QUE TIENEN UN ESPECTRO IR (CCL4) QUE MUESTRA UNA BANDA ANCHA CERCA DE 1.665 CM-1 RECOGIENDO LOS COMPUESTOS QUE TIENEN UN ESPECTRO IR (CCL4) QUE MUESTRA UNA BANDA CERCA DE 1.675 CM-1 Y, CUANDO SE DESEE, PREPARANDO UNA SAL DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLE DE LOS MISMOS. LOS NUEVOS COMPUESTOS OBTENIDOS CON EL PROCEDIMIENTO TIENEN UTILIDAD FARMACEUTICA.
ES8700631A 1986-02-17 1987-02-17 Procedimiento de preparar compuestos del tipo de las piracinas y analogos. Expired ES2004255A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19431/86A IT1204803B (it) 1986-02-17 1986-02-17 Composto farmacologicamente attivo e composizioni farmaceutiche che lo contengono,procedimento per prepararlo e intermedio utile in detto procedimento

Publications (1)

Publication Number Publication Date
ES2004255A6 true ES2004255A6 (es) 1988-12-16

Family

ID=11157870

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8700631A Expired ES2004255A6 (es) 1986-02-17 1987-02-17 Procedimiento de preparar compuestos del tipo de las piracinas y analogos.

Country Status (6)

Country Link
EP (1) EP0257072A1 (es)
AU (1) AU7122387A (es)
ES (1) ES2004255A6 (es)
IT (1) IT1204803B (es)
PT (1) PT84299A (es)
WO (1) WO1987005022A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX19222A (es) * 1989-01-23 1993-12-01 Pfizer Agentes ansioliticos bis-aza-biciclicos
JP3287574B2 (ja) * 1994-09-30 2002-06-04 ファイザー・インク ２，７−置換オクタヒドロ−１ｈ−ピリド［１，２−ａ］ピラジン誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3503980A (en) * 1965-10-04 1970-03-31 Ciba Geigy Corp Tetrahydroazacycloalkano(1,2-a) pyridazines
GB1125112A (en) * 1966-01-07 1968-08-28 Science Union & Cie New derivatives of diazabicyclo-decane and process for preparing them

Also Published As

Publication number Publication date
AU7122387A (en) 1987-09-09
WO1987005022A3 (en) 1987-10-22
WO1987005022A2 (en) 1987-08-27
IT1204803B (it) 1989-03-10
PT84299A (en) 1987-03-01
IT8619431A0 (it) 1986-02-17
EP0257072A1 (en) 1988-03-02

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