ES8604911A1 - Proceso para preparar un derivado de piperazina. - Google Patents

Proceso para preparar un derivado de piperazina.

Info

Publication number
ES8604911A1
ES8604911A1 ES83524283A ES524283A ES8604911A1 ES 8604911 A1 ES8604911 A1 ES 8604911A1 ES 83524283 A ES83524283 A ES 83524283A ES 524283 A ES524283 A ES 524283A ES 8604911 A1 ES8604911 A1 ES 8604911A1
Authority
ES
Spain
Prior art keywords
general formula
hydrogen atom
salts
diphenylmethylpiperazinyl
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES83524283A
Other languages
English (en)
Spanish (es)
Other versions
ES524283A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd
Publication of ES8604911A1 publication Critical patent/ES8604911A1/es
Publication of ES524283A0 publication Critical patent/ES524283A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES83524283A 1982-12-02 1983-07-20 Proceso para preparar un derivado de piperazina. Expired ES8604911A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57212036A JPS59101475A (ja) 1982-12-02 1982-12-02 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤

Publications (2)

Publication Number Publication Date
ES8604911A1 true ES8604911A1 (es) 1986-03-16
ES524283A0 ES524283A0 (es) 1986-03-16

Family

ID=16615802

Family Applications (2)

Application Number Title Priority Date Filing Date
ES83524283A Expired ES8604911A1 (es) 1982-12-02 1983-07-20 Proceso para preparar un derivado de piperazina.
ES543397A Granted ES543397A0 (es) 1982-12-02 1985-05-22 Proceso para preparar un derivado de piperazina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES543397A Granted ES543397A0 (es) 1982-12-02 1985-05-22 Proceso para preparar un derivado de piperazina

Country Status (11)

Country Link
US (1) US4528194A (enExample)
JP (1) JPS59101475A (enExample)
KR (1) KR900003277B1 (enExample)
BR (1) BR8304319A (enExample)
CH (1) CH655719A5 (enExample)
DE (1) DE3326148A1 (enExample)
ES (2) ES8604911A1 (enExample)
FR (1) FR2541275B1 (enExample)
GB (2) GB8318683D0 (enExample)
IT (1) IT1162913B (enExample)
SE (1) SE464707B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3424685A1 (de) * 1984-07-05 1986-02-06 Beiersdorf Ag, 2000 Hamburg Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPS61161272A (ja) * 1985-01-11 1986-07-21 Kanebo Ltd 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
JPH08776B2 (ja) * 1986-08-20 1996-01-10 日本ケミフア株式会社 脳細胞保護作用を有する医薬組成物
EP0354068B1 (en) * 1988-08-05 1994-06-15 Nippon Chemiphar Co., Ltd. Optically active piperazine derivative
WO1990013539A1 (fr) * 1989-04-28 1990-11-15 Meiji Seika Kaisha, Ltd. Nouveaux derives de piperazine a substitution n et medicament de traitement des troubles fonctionnels du cerveau
JP2679872B2 (ja) * 1989-04-28 1997-11-19 明治製菓株式会社 Ｎ−置換ピペラジン誘導体を含む脳機能障害改善剤
DE4108527A1 (de) * 1991-03-15 1992-09-17 Basf Ag Neue 1-(4-cyano-4-aryl-cyclohexyl)piperazine, ihre herstellung und verwendung
DE4404249C2 (de) * 1994-02-10 2001-10-18 Basf Ag Substituierte Cycloalkyl-piperazinyl-ethanol, ihre Herstellung und diese enthaltende Arzneimittel
KR100472086B1 (ko) * 2001-11-23 2005-02-21 한국화학연구원 항산화 활성을 갖는 3,5-디알콕시-4-히드록시페닐기로치환된 피페라진 유도체, 그의 제조방법 및 이를 포함하는약학적 조성물
US8186436B2 (en) * 2009-09-10 2012-05-29 Warren Carlos Thermal insulating packer fluid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131192C (enExample) * 1965-06-16
FR2081579B1 (enExample) * 1970-03-18 1973-04-06 Delalande Sa
FR2163358A1 (en) * 1971-12-15 1973-07-27 Synthelabo Phenylalkanolamine derivs - with effects on the smooth musculature
NL7306771A (enExample) * 1972-06-02 1973-12-04
JPS504087A (enExample) * 1973-05-17 1975-01-16

Also Published As

Publication number Publication date
ES8603449A1 (es) 1986-01-01
JPH0254832B2 (enExample) 1990-11-22
ES524283A0 (es) 1986-03-16
CH655719A5 (fr) 1986-05-15
IT8367776A0 (it) 1983-07-19
KR840006983A (ko) 1984-12-04
GB8319317D0 (en) 1983-08-17
US4528194A (en) 1985-07-09
SE8304071L (sv) 1984-06-03
SE464707B (sv) 1991-06-03
GB2131016A (en) 1984-06-13
GB2131016B (en) 1985-11-20
DE3326148A1 (de) 1984-06-07
FR2541275A1 (fr) 1984-08-24
IT8367776A1 (it) 1985-01-19
IT1162913B (it) 1987-04-01
FR2541275B1 (fr) 1986-02-07
ES543397A0 (es) 1986-01-01
BR8304319A (pt) 1984-11-06
SE8304071D0 (sv) 1983-07-20
GB8318683D0 (en) 1983-08-10
JPS59101475A (ja) 1984-06-12
KR900003277B1 (ko) 1990-05-12
DE3326148C2 (enExample) 1989-11-16

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