ES8201530A1 - Procedimiento de preparar cicloalquil propanol aminas - Google Patents
Procedimiento de preparar cicloalquil propanol aminasInfo
- Publication number
- ES8201530A1 ES8201530A1 ES500978A ES500978A ES8201530A1 ES 8201530 A1 ES8201530 A1 ES 8201530A1 ES 500978 A ES500978 A ES 500978A ES 500978 A ES500978 A ES 500978A ES 8201530 A1 ES8201530 A1 ES 8201530A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- radical
- alkyl
- preparation
- see diagramm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE CICLOALQUIL PROPANOLAMINAS DE FORMULA (I), ASI COMO DE SUS SALES DE ACIDOS FISIOLOGICAMENTE COMPATIBLES, FORMULA EN LA QUE A ES UN RADICAL CICLICO CARBONADO NO AROMATICO; R1 ES RADICAL ALQUILO O ACILO; R2 ES HIDROGENO O UN RADICAL ALQUILO; B ES METILENO; M VALE 0-2; Y R PUEDE SER VARIOS RADICALES. CONSISTE EN LA REACCION DE UN EPOXIDO DE FORMULA (II) CON UNA AMINA DE FORMULA R-NH2, EN LAS QUE R1, R2, R, A, B Y M TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN METANOL A TEMPERATURA AMBIENTE. EL EPOXIDO DE FORMULA (II) SE OBTIENE POR REACCION DE EPICLORHIDRINA CON UN ALCOHOL DE FORMULA (III) EN PRESENCIA DE HIDROXIDO SODICO Y DE UN COMPUESTO DE AMONIO CUATERNARIO COMO CATALIZADOR.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8007718A FR2479812A1 (fr) | 1980-04-04 | 1980-04-04 | Cycloalcoyl propanol amines utiles comme medicaments et procede pour leur preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
ES500978A0 ES500978A0 (es) | 1982-01-01 |
ES8201530A1 true ES8201530A1 (es) | 1982-01-01 |
Family
ID=9240575
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES500978A Expired ES8201530A1 (es) | 1980-04-04 | 1981-04-01 | Procedimiento de preparar cicloalquil propanol aminas |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0037777B1 (es) |
AT (1) | ATE4800T1 (es) |
DE (1) | DE3161007D1 (es) |
ES (1) | ES8201530A1 (es) |
FR (1) | FR2479812A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2521856A1 (fr) * | 1982-02-19 | 1983-08-26 | Pos Lab | Medicament ophtalmique pour le traitement des glaucomes, a base d'ethers-oxydes ou d'ether-oximes de derives alcoylamines |
DE3704604A1 (de) * | 1987-02-13 | 1988-08-25 | Mack Chem Pharm | Oximether von 2,6-dioxabicyclo(3.3.0)octanonen, herstellungsverfahren und anwendung als arzneimittel |
CN1489637A (zh) * | 2000-12-21 | 2004-04-14 | �Ƹ��� | 铝合金产品及人工时效方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE837320A (fr) * | 1976-01-06 | 1976-05-03 | Derives ethers de 3-amino-1,2-propanodiol |
-
1980
- 1980-04-04 FR FR8007718A patent/FR2479812A1/fr active Granted
-
1981
- 1981-04-01 ES ES500978A patent/ES8201530A1/es not_active Expired
- 1981-04-02 DE DE8181400528T patent/DE3161007D1/de not_active Expired
- 1981-04-02 EP EP81400528A patent/EP0037777B1/fr not_active Expired
- 1981-04-02 AT AT81400528T patent/ATE4800T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES500978A0 (es) | 1982-01-01 |
EP0037777A1 (fr) | 1981-10-14 |
FR2479812A1 (fr) | 1981-10-09 |
FR2479812B1 (es) | 1984-02-03 |
EP0037777B1 (fr) | 1983-09-28 |
ATE4800T1 (de) | 1983-10-15 |
DE3161007D1 (en) | 1983-11-03 |
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