MX3034E - Procedimiento para preparar esteres de acido alquil iden amino oxi alquil carboxilico - Google Patents

Procedimiento para preparar esteres de acido alquil iden amino oxi alquil carboxilico

Info

Publication number
MX3034E
MX3034E MX002414U MX241471U MX3034E MX 3034 E MX3034 E MX 3034E MX 002414 U MX002414 U MX 002414U MX 241471 U MX241471 U MX 241471U MX 3034 E MX3034 E MX 3034E
Authority
MX
Mexico
Prior art keywords
group
alkyl
see
formula
compound
Prior art date
Application number
MX002414U
Other languages
English (en)
Inventor
John Van Dijk
Johannes Maria Ant Zwagemakers
Original Assignee
Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL7008493A external-priority patent/NL166683C/xx
Priority claimed from NL7102715A external-priority patent/NL7102715A/xx
Application filed by Philips Nv filed Critical Philips Nv
Publication of MX3034E publication Critical patent/MX3034E/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/32—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a un procedimiento para preparar ésteres de ácidos alquilidenaminooxialquilcarboxílicos, caracterizados porque un compuesto de la fórmula: ( VER FIGURA) y sus sales de adición, en donde A representa un átomo de azufre o un grupo -CH_CH, R1 es un átomo de halógeno o un grupo metilo, R2 es un átomo de hidrógeno o halógeno R3 es un átomo de hidrógeno o un grupo metilo, R4 es un grupo alquileno recto o ramificado, que contiene de 1 a 3 átomos de carbono, R5 es un grupo alquileno ramificado o recto, que contiene de 1 a 3 átomos de carbono, cuyo grupo puede ser substituído por un grupo fenilo, R6 y R7 cada uno representa hidrógeno, metilo o etilo, que puede ser substituído por un grupo aciloxi de la fórmula ( VER FIGURA ) en la que A, R2, R3, y R4 tienen los significados indicados antes, R6 y R7 representan un grupo acetilo o fenilo, y R6 junto con R7 y el átomo de nitrógeno, representan un grupo pirrolidino, piperidino o morfolino, es preparado mediante la reacción de un compuesto de la fórmula: ( VER FIGURA ) o su sal, con un compuesto de la fórmula ( VER FIGURA ) en un solvente inerte, a una temperatura entre 0 y 100°C., en cuyas fórmulas A, R1, R2, R3, R4, R5, R6 y R7 tienen los significados anteriores, E representa cloro cuando B es hidroxi, o E es hidroxi cuando B es cloro.
MX002414U 1970-06-11 1971-06-08 Procedimiento para preparar esteres de acido alquil iden amino oxi alquil carboxilico MX3034E (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7008493A NL166683C (nl) 1970-06-11 1970-06-11 Werkwijze ter bereiding of vervaardiging van anti- -inflammatoir en analgetisch werkzame preparaten en werkwijze ter bereiding van benzylideenamino-oxyal- kaancarbonzuuresters met anti-inflammatoire en analgetische werking.
NL7102715A NL7102715A (en) 1971-03-02 1971-03-02 Phenyl-or thienyl-alkylidene amino-oxy-alkanoic acid basic esters - - as anti-inflammatory agents and analgesics

Publications (1)

Publication Number Publication Date
MX3034E true MX3034E (es) 1980-02-29

Family

ID=26644549

Family Applications (2)

Application Number Title Priority Date Filing Date
MX002414U MX3034E (es) 1970-06-11 1971-06-08 Procedimiento para preparar esteres de acido alquil iden amino oxi alquil carboxilico
MX002463U MX3077E (es) 1970-06-11 1971-06-08 Procedimiento para preparar esteres de acidos bencil iden amino - oxi alquil - carboxilicos

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX002463U MX3077E (es) 1970-06-11 1971-06-08 Procedimiento para preparar esteres de acidos bencil iden amino - oxi alquil - carboxilicos

Country Status (14)

Country Link
US (3) US3853955A (es)
AR (4) AR205682A1 (es)
AT (4) AT313254B (es)
BE (1) BE768321A (es)
CA (1) CA947763A (es)
CH (4) CH571482A5 (es)
DE (1) DE2128375C3 (es)
DK (1) DK129513B (es)
ES (1) ES392072A1 (es)
FR (1) FR2100751B1 (es)
GB (1) GB1325231A (es)
IL (1) IL37013A (es)
MX (2) MX3034E (es)
SE (1) SE401177B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT998326B (it) * 1973-08-06 1976-01-20 Montedison Spa Derivati degli acidi chinolin 8 carbossilici ad attivita antiparas sitaria
CH632130A5 (en) * 1977-03-02 1982-09-30 Ciba Geigy Ag Compositions on the basis of oxime ethers, oxime esters or oxime carbamates which are suitable in agriculture for crop protection
GB1599181A (en) * 1977-04-01 1981-09-30 Ici Ltd Oxyalkanoic acid derivatives
GB1582884A (en) * 1977-05-19 1981-01-14 Beecham Group Ltd Clavulanic acid derivatives their preparation and use
US4347372A (en) * 1978-09-01 1982-08-31 Ciba-Geigy Corporation Benzoxazolyl-glyoxylonitrile-2-oxime ether derivatives
DK330880A (da) * 1979-08-03 1981-02-04 Beecham Group Ltd Fremgangsmaade til fremstilling af clavulansyrederivater
EP0053893B1 (en) * 1980-12-09 1985-03-20 Beecham Group Plc Derivatives of clavulanic acid, their preparation and their use
US4562182A (en) * 1980-12-23 1985-12-31 Beecham Group P.L.C. Compounds containing beta-lactams
JP4517634B2 (ja) 2003-11-26 2010-08-04 いすゞ自動車株式会社 流体継手

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2352516A (en) * 1942-11-18 1944-06-27 Resinous Prod & Chemical Co Oximino ether
US3692835A (en) * 1967-04-05 1972-09-19 Jan Van Dijk Pharmacologically active amino-ethyl oximes
NL6818074A (es) * 1968-12-17 1970-06-19
NL6905499A (es) * 1969-04-10 1970-10-13
NL7107360A (es) * 1971-05-28 1972-11-30

Also Published As

Publication number Publication date
US4242348A (en) 1980-12-30
MX3077E (es) 1980-03-20
CH561179A5 (es) 1975-04-30
IL37013A (en) 1975-05-22
FR2100751A1 (es) 1972-03-24
AT313875B (de) 1974-03-11
CH571481A5 (es) 1976-01-15
DE2128375A1 (de) 1971-12-16
DE2128375B2 (de) 1980-06-26
BE768321A (fr) 1971-11-03
FR2100751B1 (es) 1974-08-30
US4317835A (en) 1982-03-02
DE2128375C3 (de) 1982-05-13
IL37013A0 (en) 1971-08-25
CH571482A5 (es) 1976-01-15
US3853955A (en) 1974-12-10
CH568968A5 (es) 1975-11-14
AR205682A1 (es) 1976-05-31
ES392072A1 (es) 1974-05-01
AT313254B (de) 1974-02-11
AR197624A1 (es) 1974-04-23
GB1325231A (en) 1973-08-01
CA947763A (en) 1974-05-21
AR197517A1 (es) 1974-04-15
AT313255B (de) 1974-02-11
DK129513C (es) 1975-03-17
AT313256B (de) 1974-02-11
AR197623A1 (es) 1974-04-23
SE401177B (sv) 1978-04-24
DK129513B (da) 1974-10-21

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