ES8604480A1 - Un procedimiento para la preparacion de la sal con n-metil-d-glucamina del acido (+)-2-(2-fluoro-4-bifenilil)propionico. - Google Patents

Un procedimiento para la preparacion de la sal con n-metil-d-glucamina del acido (+)-2-(2-fluoro-4-bifenilil)propionico.

Info

Publication number
ES8604480A1
ES8604480A1 ES517984A ES517984A ES8604480A1 ES 8604480 A1 ES8604480 A1 ES 8604480A1 ES 517984 A ES517984 A ES 517984A ES 517984 A ES517984 A ES 517984A ES 8604480 A1 ES8604480 A1 ES 8604480A1
Authority
ES
Spain
Prior art keywords
methyl
glucamine
fluoro
organic solvent
propionic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES517984A
Other languages
English (en)
Spanish (es)
Other versions
ES517984A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of ES517984A0 publication Critical patent/ES517984A0/es
Publication of ES8604480A1 publication Critical patent/ES8604480A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ES517984A 1981-12-08 1982-12-07 Un procedimiento para la preparacion de la sal con n-metil-d-glucamina del acido (+)-2-(2-fluoro-4-bifenilil)propionico. Expired ES8604480A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8136989 1981-12-08

Publications (2)

Publication Number Publication Date
ES517984A0 ES517984A0 (es) 1986-02-01
ES8604480A1 true ES8604480A1 (es) 1986-02-01

Family

ID=10526449

Family Applications (1)

Application Number Title Priority Date Filing Date
ES517984A Expired ES8604480A1 (es) 1981-12-08 1982-12-07 Un procedimiento para la preparacion de la sal con n-metil-d-glucamina del acido (+)-2-(2-fluoro-4-bifenilil)propionico.

Country Status (23)

Country Link
US (1) US4501727A (ref)
JP (1) JPS58113144A (ref)
AT (1) AT391688B (ref)
AU (1) AU555937B2 (ref)
BE (1) BE895269A (ref)
CA (1) CA1202329A (ref)
CH (1) CH654288A5 (ref)
DE (1) DE3245469A1 (ref)
DK (1) DK541782A (ref)
ES (1) ES8604480A1 (ref)
FI (1) FI73964C (ref)
FR (1) FR2517670B1 (ref)
GB (1) GB2111493B (ref)
GR (1) GR77840B (ref)
IE (1) IE54266B1 (ref)
IT (1) IT1196426B (ref)
LU (1) LU84512A1 (ref)
NL (1) NL8204471A (ref)
NO (1) NO156165C (ref)
NZ (1) NZ202672A (ref)
PT (1) PT75889B (ref)
SE (1) SE459090B (ref)
ZA (1) ZA828453B (ref)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
US4883818A (en) * 1987-11-17 1989-11-28 Analgesic Associates Onset-hastened/enhanced analgesia
US5286751A (en) * 1987-12-24 1994-02-15 Analgesic Associates Sustained/enhanced antipyretic response
US4927854A (en) * 1987-12-24 1990-05-22 Analgesic Associates Sustained/enhanced analgesia
DE4028906A1 (de) † 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
HUT59692A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alkanoic acids and aminosugars
US5621140A (en) * 1994-12-22 1997-04-15 Syntex (U.S.A.) Inc. Resolution of ibuprofen
IN189741B (ref) * 1998-11-09 2003-04-19 Council Scient Ind Res
WO2002026239A1 (en) * 2000-09-26 2002-04-04 Temple University Of The Commonwealth System Of Higher Education Analgesic and glucosamine compositions
ITMI20040235A1 (it) * 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale
JP5264478B2 (ja) * 2005-04-29 2013-08-14 ユニバーシティー オブ ルイヴィル リサーチ ファウンデーション，インコーポレーテッド 活性物質での細胞表面の装飾
US20070237816A1 (en) * 2006-04-06 2007-10-11 David Finkelstein Acetaminophen formulation for joint pain relief

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1091403A (en) * 1964-01-24 1967-11-15 Boots Pure Drug Co Ltd Therapeutically active phenylalkane derivatives
ES383442A1 (es) * 1970-09-07 1973-01-01 Gallardo Antonio Sa Procedimiento para la obtencion de una nueva sal de n-me- tilglucamina con el acido 6-d-(-)-alfa-amino fenil-acetamido-penicilanico.
GB1359987A (en) * 1970-10-12 1974-07-17 Boots Co Ltd 2-substituted biphenylyl propionic acids
FR2133556A1 (en) * 1971-04-21 1972-12-01 Farmaceutici Chiesi Snc Indomethacin n-methyl-d-glucamine salt - with anti-inflammatory activity with reduced side effects and improved water-solubility
US3985788A (en) * 1971-07-21 1976-10-12 William H. Rorer, Inc. Phenyl propionic acids and derivatives thereof
US3860624A (en) * 1971-07-21 1975-01-14 Rorer Inc William H P-cyclohexyl alpha - lower alkanoylthio hydrocinamic acid
US3903134A (en) * 1971-07-21 1975-09-02 Rorer Inc William H Phenyl propionic acids and derivatives thereof
US3987197A (en) * 1972-08-17 1976-10-19 Boehringer Ingelheim Gmbh 3-(2'-fluoro-4-biphenylyl)-butyric acid and salts thereof
US3891761A (en) * 1973-03-28 1975-06-24 Schering Corp N-Methyl-d-glucamine salt of 2(2-methyl-3{40 -trifluoro-methylanilino) nicotinic acid in the treatment of pain
US4209638A (en) * 1977-03-08 1980-06-24 The Boots Company Limited Preparation of therapeutic agents
FR2413353A1 (fr) * 1977-12-27 1979-07-27 Fabre Sa Pierre L'acetyl salicylate de n-methyl glucamine, nouveau derive hydrosoluble
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.
PH15674A (en) * 1979-07-06 1983-03-11 Syntex Corp Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid
LU83138A1 (de) * 1981-02-16 1981-09-11 T Eckert Topische pharmazeutische praeparate,enthaltend salze von alkancarbonsaeuren sowie neue carbonsaeuresalze und verfahren zu ihrer herstellung
BE887671A (fr) * 1981-02-25 1981-08-25 Eckert Theod P Preparations pharmaceutiques topiques contenant des sels d'acides alcane-carboxyliques ainsi que de nouveaux sels d'acides carboxyliques et leurs procedes de preparation

Also Published As

Publication number Publication date
PT75889A (en) 1982-12-01
JPH047337B2 (ref) 1992-02-10
FI824098A0 (fi) 1982-11-29
FR2517670A1 (fr) 1983-06-10
NO156165C (no) 1987-08-05
DE3245469A1 (de) 1983-07-21
FI73964C (fi) 1987-12-10
NO156165B (no) 1987-04-27
PT75889B (en) 1985-11-15
IT8224624A1 (it) 1984-06-06
SE8206984L (sv) 1983-06-09
IT8224624A0 (it) 1982-12-06
GR77840B (ref) 1984-09-25
IT1196426B (it) 1988-11-16
GB2111493A (en) 1983-07-06
BE895269A (fr) 1983-06-07
DE3245469C2 (ref) 1991-11-07
AT391688B (de) 1990-11-12
US4501727A (en) 1985-02-26
CH654288A5 (fr) 1986-02-14
CA1202329A (en) 1986-03-25
ATA443282A (de) 1990-05-15
LU84512A1 (fr) 1984-03-07
SE459090B (sv) 1989-06-05
NZ202672A (en) 1984-09-28
DK541782A (da) 1983-06-09
AU9084582A (en) 1983-06-16
ZA828453B (en) 1983-12-28
ES517984A0 (es) 1986-02-01
FI824098L (fi) 1983-06-09
FR2517670B1 (fr) 1986-06-20
NL8204471A (nl) 1983-07-01
JPS58113144A (ja) 1983-07-05
SE8206984D0 (sv) 1982-12-07
AU555937B2 (en) 1986-10-16
IE822766L (en) 1983-06-08
NO824112L (no) 1983-06-09
IE54266B1 (en) 1989-08-02
GB2111493B (en) 1985-06-12
FI73964B (fi) 1987-08-31

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