ES8707257A1 - Procedimiento para preparar derivados de aminoacidos - Google Patents

Procedimiento para preparar derivados de aminoacidos

Info

Publication number
ES8707257A1
ES8707257A1 ES555389A ES555389A ES8707257A1 ES 8707257 A1 ES8707257 A1 ES 8707257A1 ES 555389 A ES555389 A ES 555389A ES 555389 A ES555389 A ES 555389A ES 8707257 A1 ES8707257 A1 ES 8707257A1
Authority
ES
Spain
Prior art keywords
alkyl
phenyl
image
branched
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES555389A
Other languages
English (en)
Other versions
ES555389A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Publication of ES555389A0 publication Critical patent/ES555389A0/es
Publication of ES8707257A1 publication Critical patent/ES8707257A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE AMINOACIDOS, DE FORMULA (I), Y DE SUS SALES. CONSISTE EN LA REACCION DE SUSTITUCION DE UN COMPUESTO DE FORMULA (II) CON UN MERCAPTO DE FORMULA HS-R2, PARA FORMAR UN COMPUESTO DE FORMULA (I), EN LA QUE A, R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES. LA REACCION SE LLEVA A CABO EN UN ETER COMO DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU EFECTO HIPOTENSOR.43
ES555389A 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos Expired ES8707257A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843432307 DE3432307A1 (de) 1984-09-03 1984-09-03 Aminosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen

Publications (2)

Publication Number Publication Date
ES555389A0 ES555389A0 (es) 1987-07-01
ES8707257A1 true ES8707257A1 (es) 1987-07-01

Family

ID=6244509

Family Applications (7)

Application Number Title Priority Date Filing Date
ES546649A Expired ES8704183A1 (es) 1984-09-03 1985-09-02 Procedimiento para preparar derivados de aminoacidos
ES555390A Expired ES8707258A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555392A Expired ES8707260A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555389A Expired ES8707257A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555388A Expired ES8706720A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555393A Expired ES8800895A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar compuestos dimeros de derivados de aminoacidos.
ES555391A Expired ES8707259A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES546649A Expired ES8704183A1 (es) 1984-09-03 1985-09-02 Procedimiento para preparar derivados de aminoacidos
ES555390A Expired ES8707258A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555392A Expired ES8707260A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES555388A Expired ES8706720A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos
ES555393A Expired ES8800895A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar compuestos dimeros de derivados de aminoacidos.
ES555391A Expired ES8707259A1 (es) 1984-09-03 1986-05-28 Procedimiento para preparar derivados de aminoacidos

Country Status (19)

Country Link
EP (1) EP0174571A3 (es)
JP (1) JPS6183199A (es)
KR (1) KR860002463A (es)
AU (1) AU4702285A (es)
CS (1) CS254345B2 (es)
DD (1) DD240547A5 (es)
DE (1) DE3432307A1 (es)
DK (1) DK400085A (es)
ES (7) ES8704183A1 (es)
FI (1) FI853354L (es)
GR (1) GR852112B (es)
HU (1) HUT39191A (es)
IL (1) IL76282A0 (es)
NO (1) NO853444L (es)
NZ (1) NZ213317A (es)
PL (1) PL255220A1 (es)
PT (1) PT81078B (es)
SU (1) SU1468411A3 (es)
ZA (1) ZA856691B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3705656A1 (de) * 1987-02-21 1988-09-01 Boehringer Ingelheim Kg Aminosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3731085A1 (de) * 1987-09-16 1989-04-06 Hoechst Ag Neue aminosaeureester, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE102006004063A1 (de) * 2006-01-28 2007-08-02 Degussa Gmbh Verfahren zur Herstellung von Methionin aus Homoserin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU537592B2 (en) * 1979-04-02 1984-07-05 E.R. Squibb & Sons, Inc. Mercaptoacyldipeptides
EP0065301A1 (en) * 1981-05-18 1982-11-24 Merck & Co. Inc. Isoquinoline carboxylic acid derivates, process for preparing and pharmaceutical composition containing the same
IT1195287B (it) * 1981-11-05 1988-10-12 Ausonia Farma Srl Derivato tiazolico,procedimento per la sua preparazione e relative composizioni farmaceutiche
DE3243370A1 (de) * 1982-11-24 1984-05-24 Basf Ag, 6700 Ludwigshafen Benzoylthioverbindungen, ihre herstellung und verwendung als arzneimittel
DE3302125A1 (de) * 1983-01-22 1984-07-26 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung

Also Published As

Publication number Publication date
EP0174571A3 (de) 1989-01-11
HUT39191A (en) 1986-08-28
NZ213317A (en) 1987-11-27
DD240547A5 (de) 1986-11-05
ES555388A0 (es) 1987-07-01
AU4702285A (en) 1986-03-13
FI853354L (fi) 1986-03-04
CS624285A2 (en) 1987-06-11
EP0174571A2 (de) 1986-03-19
ES8800895A1 (es) 1987-12-01
NO853444L (no) 1986-03-04
SU1468411A3 (ru) 1989-03-23
DK400085A (da) 1986-03-04
ES555391A0 (es) 1987-07-01
ES8707259A1 (es) 1987-07-01
PT81078A (de) 1985-10-01
DE3432307A1 (de) 1986-04-10
DK400085D0 (da) 1985-09-02
ES546649A0 (es) 1987-03-16
FI853354A0 (fi) 1985-09-02
IL76282A0 (en) 1986-01-31
ES555393A0 (es) 1987-12-01
GR852112B (es) 1985-12-24
PT81078B (de) 1987-07-10
ES555389A0 (es) 1987-07-01
PL255220A1 (en) 1988-03-31
ES8707258A1 (es) 1987-07-01
CS254345B2 (en) 1988-01-15
KR860002463A (ko) 1986-04-26
ES555390A0 (es) 1987-07-01
ES555392A0 (es) 1987-07-01
ES8706720A1 (es) 1987-07-01
JPS6183199A (ja) 1986-04-26
ZA856691B (en) 1987-05-27
ES8707260A1 (es) 1987-07-01
ES8704183A1 (es) 1987-03-16

Similar Documents

Publication Publication Date Title
ES8609245A1 (es) Un procedimiento para la preparacion de acidos indol-2-alcanoicos.
AR004495A1 (es) Compuestos derivados de acido amino sustituido arilo y heteroarilo carboxilico; composicion farmaceutica que los contiene; uso de los compuestos; proceso para preparar dichos compuestos y compuestos utiles como material de partida.
AR004670A1 (es) Compuestos derivados de acido amino sustituido arilo y heteroarilo carboxilico; composicion farmaceutica que los contiene; metodo para aliviar eldolor; procedimiento para preparar dichos compuestos y compuestos utiles como material de partida
ES8608520A1 (es) Un procedimiento para preparar derivados de 3-aminopirazolo-(3,4-d)-pirimidina
ES8404977A1 (es) Una acilanilida.
SE8204918L (sv) Nya 3-amino-pregn-5-en-derivat, deras salter, sett for framstellning och anvendning derav som lekemedel och kompositioner innehallande dem
DE3474140D1 (en) Imidazole-ethanol esters
ES8704917A1 (es) Procedimiento para prepararar derivados de 1-piperazinacarboximida.
ES8800895A1 (es) Procedimiento para preparar compuestos dimeros de derivados de aminoacidos.
ES8704185A1 (es) Procedimiento para preparar derivados de aminoacidos
KR920007999A (ko) 4-또는 5-치환된 피리딘-2-카복실산. 이들의 제조방법 및 약제로서 이들의 용도
FI830893A0 (fi) Nya fenylpiperazin-derivat samt deras framstaellningsfoerfarande
PT76335A (de) Neue basisch substituierte 4-phenyl-4,5,6,7-tetrahydro-thieno-<2,3-c>pyridine verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
GB1201984A (en) Oral compositions for calculus retardation
IT1260467B (it) Medicamento contenente arg-gly-asp per il trattamento del glaucoma
JPS50157362A (es)
ES469149A2 (es) Un procedimiento para la preparacion de compuestos antibio- ticos de cefalosporina.
IT1270995B (it) Derivati dell'acido 2-(2-azetidinon-n-il)-3-butenoico e loro uso nella sintesi di cefalosporine
ES419813A1 (es) Un procedimiento para la preparacion de nuevos derivados depenama y cefama.
JPS51113890A (en) Method for preparing novel cephalosporins
ES300712A1 (es) Procedimiento para la preparación de derivados de benzo[a]quinolizina
JPS52133972A (en) Synthesis of gamma-lactam esters
JPS5481292A (en) Preparation of cephalosporin compound
DK559986A (da) Via 4-, 5-, 6- eller 7-stillingen koblede indoler eller indolderivater samt anvendelse heraf
ES315987A1 (es) Procedimiento para la preparacion de nuevas amidas en acidos grasos insaturados