ES8602255A1 - Un procedimiento para detectar y-o determinar un aglomerado formado por reaccion entre un agente de union especifico y la correspondiente sustancia aceptora - Google Patents
Un procedimiento para detectar y-o determinar un aglomerado formado por reaccion entre un agente de union especifico y la correspondiente sustancia aceptoraInfo
- Publication number
- ES8602255A1 ES8602255A1 ES537926A ES537926A ES8602255A1 ES 8602255 A1 ES8602255 A1 ES 8602255A1 ES 537926 A ES537926 A ES 537926A ES 537926 A ES537926 A ES 537926A ES 8602255 A1 ES8602255 A1 ES 8602255A1
- Authority
- ES
- Spain
- Prior art keywords
- reaction
- binding agent
- specific binding
- direct
- acceptor substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000006243 chemical reaction Methods 0.000 title abstract 4
- 239000011230 binding agent Substances 0.000 title abstract 3
- 230000009870 specific binding Effects 0.000 title abstract 3
- 238000003556 assay Methods 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 238000007794 visualization technique Methods 0.000 title 1
- 230000008878 coupling Effects 0.000 abstract 2
- 238000010168 coupling process Methods 0.000 abstract 2
- 238000005859 coupling reaction Methods 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 1
- 239000002923 metal particle Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
- G01N33/559—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody through a gel, e.g. Ouchterlony technique
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Communication Control (AREA)
- Details Of Television Scanning (AREA)
- Conductive Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
Abstract
METODO PARA LA DETECCION Y/O DETERMINACION EN ENSAYOS DE TRANSFERENCIA POR SUPERPOSICION DE UN AGLOMERADO FORMADO POR UN AGENTE DE UNION Y LA CORRESPONDIENTE SUSTANCIA ACEPTORA. COMPRENDE LAS ETAPAS DE: A) INMOVILIZAR LA SUSTANCIA ACEPTORA SOBRE UNA MATRIZ INMOVILIZANTE, B) PONER EN CONTACTO DICHA MATRIZ INMOVILIZANTE CON UNA PROTEINA DE UNION ESPECIFICA MARCADA CON PARTICULAS METALICAS COLOIDALES; O BIEN CON UNA PROTEINA DE UNION ESPECIFICA NO MARCADA Y POSTERIORMENTE CON UNA PROTEINA MARCADA CON METAL COLOIDAL ESPECIFICA PARA LA PROTEINA NO MARCADA, Y C) DETECTAR LA SEÑAL COLOREADA EN EL SITIO DE REACCION EN LA SUPERFICIE DE LA MATRIZ INMOVILIZANTE DESPUES DE HABER APLICADO UN REVELADOR FISICO QUE CONTIENE PLATA. LAS PARTICULAS METALICAS COLOIDALES ESTAN CONSTITUIDAS POR ORO, PLATA, PLATINO O COMPUESTOS DE ESTOS METALES O COMPUESTOS DE HIERRO O COBRE CON UN TAMAÑO DE PARTICULA COMPRENDIDO ENTRE 3 NM Y 100 NM.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838331514A GB8331514D0 (en) | 1983-11-25 | 1983-11-25 | Visualization method |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8602255A1 true ES8602255A1 (es) | 1985-11-01 |
ES537926A0 ES537926A0 (es) | 1985-11-01 |
Family
ID=10552346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES537926A Granted ES537926A0 (es) | 1983-11-25 | 1984-11-23 | Un procedimiento para detectar y-o determinar un aglomerado formado por reaccion entre un agente de union especifico y la correspondiente sustancia aceptora |
Country Status (19)
Country | Link |
---|---|
US (1) | US4775636A (es) |
EP (1) | EP0158746B1 (es) |
JP (2) | JPH0643998B2 (es) |
KR (1) | KR890001131B1 (es) |
AT (1) | ATE64468T1 (es) |
AU (1) | AU583484B2 (es) |
CA (1) | CA1253422A (es) |
CY (1) | CY1759A (es) |
DE (1) | DE3484710D1 (es) |
DK (1) | DK160108C (es) |
ES (1) | ES537926A0 (es) |
FI (1) | FI80345C (es) |
GB (1) | GB8331514D0 (es) |
HK (1) | HK14894A (es) |
IL (1) | IL73607A (es) |
NO (1) | NO163754C (es) |
NZ (1) | NZ210309A (es) |
PT (1) | PT79533A (es) |
ZA (1) | ZA849182B (es) |
Families Citing this family (116)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5622871A (en) | 1987-04-27 | 1997-04-22 | Unilever Patent Holdings B.V. | Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents |
GB8415998D0 (en) * | 1984-06-22 | 1984-07-25 | Janssen Pharmaceutica Nv | Staining method |
US5958790A (en) * | 1984-12-20 | 1999-09-28 | Nycomed Imaging As | Solid phase transverse diffusion assay |
US5512332A (en) * | 1985-10-04 | 1996-04-30 | Immunivest Corporation | Process of making resuspendable coated magnetic particles |
US5137827A (en) * | 1986-03-25 | 1992-08-11 | Midwest Research Technologies, Inc. | Diagnostic element for electrical detection of a binding reaction |
AU7385387A (en) * | 1986-06-09 | 1987-12-10 | Ortho Diagnostic Systems Inc. | Immunoassay using detection of colloidal gold |
US5514602A (en) * | 1986-06-09 | 1996-05-07 | Ortho Diagnostic Systems, Inc. | Method of producing a metal sol reagent containing colloidal metal particles |
AU602694B2 (en) * | 1986-06-09 | 1990-10-25 | Ortho Diagnostic Systems Inc. | Improved colloidal gold membrane assay |
US4837145A (en) * | 1986-06-09 | 1989-06-06 | Liotta Lance A | Layered immunoassay using antibodies bound to transport particles to determine the presence of an antigen |
JPS63127160A (ja) * | 1986-06-30 | 1988-05-31 | Sukeyasu Yoneda | 特異的蛋白質の検出方法 |
US5491098A (en) * | 1987-03-09 | 1996-02-13 | Janssen Pharmaceutica N.V. | Method for depositing metal particles on a marker |
CA1340803C (en) * | 1987-03-09 | 1999-10-26 | Janssen Pharmaceutica N.V. | Method for depositing metal particles on a marker |
USRE38430E1 (en) | 1987-03-27 | 2004-02-17 | Becton, Dickinson And Company | Solid phase chromatographic immunoassay |
DE291194T1 (de) * | 1987-04-27 | 1992-03-19 | Unilever N.V., Rotterdam | Immunoassays und vorrichtungen dafuer. |
US4962023A (en) * | 1987-06-22 | 1990-10-09 | Louisiana State University, Agricultural And Mechanical College | Single incubation immuno sorbent assay method using particle labels to detect test antigen specific antibodies in presence of other antibodies |
US5120643A (en) | 1987-07-13 | 1992-06-09 | Abbott Laboratories | Process for immunochromatography with colloidal particles |
JP2581566B2 (ja) * | 1987-09-30 | 1997-02-12 | 和光純薬工業株式会社 | 鉄コロイド標識抗体及びその製法並びにこれを用いる組織細胞化学的検出方法 |
US5571667A (en) * | 1987-10-01 | 1996-11-05 | Chu; Albert E. | Elongated membrane flow-through diagnostic device and method |
US5006464A (en) * | 1987-10-01 | 1991-04-09 | E-Y Laboratories, Inc. | Directed flow diagnostic device and method |
ES2039025T3 (es) * | 1987-11-16 | 1993-08-16 | Janssen Pharmaceutica N.V. | Un agregado para determinar sustancias combinables. |
NL8702769A (nl) * | 1987-11-19 | 1989-06-16 | Holland Biotechnology | Werkwijze voor het bepalen in een testmonster van componenten van de reactie tussen een specifiek bindend eiwit en de bijbehorende bindbare stof onder toepassing van ten minste een gemerkte component, werkwijze voor het bereiden van de gemerkte component, en testkit voor de bepaling van immunocomponenten. |
GB8800702D0 (en) * | 1988-01-13 | 1988-02-10 | Nycomed As | Test method & reagent kit therefor |
US4952517A (en) * | 1988-02-08 | 1990-08-28 | Hygeia Sciences, Inc. | Positive step immunoassay |
US5202267A (en) * | 1988-04-04 | 1993-04-13 | Hygeia Sciences, Inc. | Sol capture immunoassay kit and procedure |
EP0378621A4 (en) * | 1988-05-23 | 1991-08-28 | Steffen Gay | Diagnostics and therapy for rheumatoid arthritis |
AU2684488A (en) | 1988-06-27 | 1990-01-04 | Carter-Wallace, Inc. | Test device and method for colored particle immunoassay |
US5079172A (en) | 1988-11-04 | 1992-01-07 | Board Of Trustees Operating Michigan State University | Method for detecting the presence of antibodies using gold-labeled antibodies and test kit |
WO1990005300A1 (en) * | 1988-11-10 | 1990-05-17 | Midwest Research Technologies, Inc. | Method for electrical detection of a binding reaction |
US5202268A (en) * | 1988-12-30 | 1993-04-13 | Environmental Diagnostics, Inc. | Multi-layered test card for the determination of substances in liquids |
US5028535A (en) * | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
EP0401913B1 (en) * | 1989-06-05 | 1995-01-25 | Janssen Pharmaceutica N.V. | A solid phase assay for use with a physical developer |
GB8915512D0 (en) | 1989-07-06 | 1989-08-23 | Sec Dep For Health | Silver enhanced gold-labelled immuno assay method |
US5698271A (en) * | 1989-08-22 | 1997-12-16 | Immunivest Corporation | Methods for the manufacture of magnetically responsive particles |
US6352863B1 (en) | 1990-01-19 | 2002-03-05 | La Mina, Inc. | Assay device |
US5143852A (en) * | 1990-09-14 | 1992-09-01 | Biosite Diagnostics, Inc. | Antibodies to ligand analogues and their utility in ligand-receptor assays |
EP0566695B1 (en) * | 1991-01-11 | 1999-06-02 | Quidel Corporation | A one-step lateral flow assay and nonbibulous support used therein |
US5869345A (en) * | 1991-05-29 | 1999-02-09 | Smithkline Diagnostics, Inc. | Opposable-element assay device employing conductive barrier |
US5607863A (en) * | 1991-05-29 | 1997-03-04 | Smithkline Diagnostics, Inc. | Barrier-controlled assay device |
US5877028A (en) | 1991-05-29 | 1999-03-02 | Smithkline Diagnostics, Inc. | Immunochromatographic assay device |
US6168956B1 (en) | 1991-05-29 | 2001-01-02 | Beckman Coulter, Inc. | Multiple component chromatographic assay device |
US5998220A (en) | 1991-05-29 | 1999-12-07 | Beckman Coulter, Inc. | Opposable-element assay devices, kits, and methods employing them |
US5468648A (en) * | 1991-05-29 | 1995-11-21 | Smithkline Diagnostics, Inc. | Interrupted-flow assay device |
WO1993016788A1 (en) * | 1992-02-25 | 1993-09-02 | Peter Andersen | Process for electroelution of a gel containing separated charged macromolecules, such as proteins or dna/rna, and an apparatus and means for use in the process |
US5395754A (en) * | 1992-07-31 | 1995-03-07 | Hybritech Incorporated | Membrane-based immunoassay method |
US5340746A (en) * | 1993-01-08 | 1994-08-23 | Minnesota Mining And Manufacturing Company | Composite reactive articles for the determination of cyanide |
CA2105515A1 (en) * | 1993-09-03 | 1995-03-04 | Carlos A. Santizo Lescaille | Visual immunoassay method for the detection of ligands, based on the use of opaque plastic supports |
US5712172A (en) | 1995-05-18 | 1998-01-27 | Wyntek Diagnostics, Inc. | One step immunochromatographic device and method of use |
US20010051350A1 (en) | 1995-05-02 | 2001-12-13 | Albert Nazareth | Diagnostic detection device and method |
US6551794B1 (en) | 1995-11-09 | 2003-04-22 | E. R. Squibb & Sons, Inc. | Stable biotinylated biomolecule composition |
US5691152A (en) * | 1995-11-09 | 1997-11-25 | E. R. Squibb & Sons, Inc. | Stable avidin composition |
US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
JP4025833B2 (ja) * | 1996-10-25 | 2007-12-26 | アークレイ株式会社 | 遺伝子の分析方法およびそれに用いる遺伝子分析用キット並びに遺伝子分析装置 |
JP4068677B2 (ja) * | 1996-10-25 | 2008-03-26 | アークレイ株式会社 | 遺伝子の分析方法およびそれに用いる遺伝子分析用キット |
US7153651B1 (en) | 1996-10-31 | 2006-12-26 | Inverness Medical - Biostar, Inc. | Flow-through optical assay devices providing laminar flow of fluid samples, and methods of construction thereof |
US5879951A (en) | 1997-01-29 | 1999-03-09 | Smithkline Diagnostics, Inc. | Opposable-element assay device employing unidirectional flow |
US6103536A (en) | 1997-05-02 | 2000-08-15 | Silver Lake Research Corporation | Internally referenced competitive assays |
US5939252A (en) | 1997-05-09 | 1999-08-17 | Lennon; Donald J. | Detachable-element assay device |
EP1121198A1 (en) * | 1998-10-14 | 2001-08-08 | Arizona Board of Regents | Immobilized silver immunoassay system |
IL126776A (en) * | 1998-10-27 | 2001-04-30 | Technion Res & Dev Foundation | A method of investing gold |
US6136610A (en) | 1998-11-23 | 2000-10-24 | Praxsys Biosystems, Inc. | Method and apparatus for performing a lateral flow assay |
US6136044A (en) * | 1999-02-03 | 2000-10-24 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Stable coloring by in situ formation of micro-particles |
JP2003527584A (ja) * | 2000-03-09 | 2003-09-16 | ヘスカ コーポレイション | 動物の免疫状態を決定するための組換え抗原の使用 |
US6699722B2 (en) | 2000-04-14 | 2004-03-02 | A-Fem Medical Corporation | Positive detection lateral-flow apparatus and method for small and large analytes |
DE10108359B4 (de) * | 2001-02-21 | 2008-03-27 | Enßlin, Walther, Dr. | Nachweisverfahren für reduzierende Substanzen |
WO2002100444A1 (en) * | 2001-06-08 | 2002-12-19 | Biosphere Medical Inc. | Colloidal metal labelled microparticles, their production and use |
US20030013084A1 (en) * | 2001-07-12 | 2003-01-16 | Berlock Aps | Organometallic probe |
AU2003213729A1 (en) * | 2002-03-05 | 2003-09-22 | Board Of Regents, The University Of Texas System | Biospecific contrast agents |
US7138468B2 (en) | 2002-03-27 | 2006-11-21 | University Of Southern Mississippi | Preparation of transition metal nanoparticles and surfaces modified with (CO)polymers synthesized by RAFT |
ES2525318T3 (es) * | 2002-10-11 | 2014-12-22 | Zbx Corporation | Dispositivos de diagnóstico |
US7736890B2 (en) * | 2003-12-31 | 2010-06-15 | President And Fellows Of Harvard College | Assay device and method |
US7638093B2 (en) * | 2004-01-28 | 2009-12-29 | Dnt Scientific Research, Llc | Interrupted flow rapid confirmatory immunological testing device and method |
US7465587B2 (en) | 2004-12-03 | 2008-12-16 | Genzyme Corporation | Diagnostic assay device |
US20060292700A1 (en) * | 2005-06-22 | 2006-12-28 | Naishu Wang | Diffused interrupted lateral flow immunoassay device and method |
EP1891447B1 (en) * | 2005-05-23 | 2011-07-06 | Phadia AB | Two step lateral flow assay methods and devices |
US20070015166A1 (en) * | 2005-07-14 | 2007-01-18 | Nilsen Thor W | Lateral flow methods and devices for detection of nucleic acid binding proteins |
US8110406B2 (en) | 2005-11-25 | 2012-02-07 | Japan Advanced Institute Of Science And Technology | Analytical method and analytical apparatus |
US11906512B2 (en) | 2006-03-31 | 2024-02-20 | Zeus Diagnostics, LLC | Integrated device for analyte testing, confirmation, and donor identity verification |
US8940527B2 (en) * | 2006-03-31 | 2015-01-27 | Lamina Equities Corp. | Integrated device for analyte testing, confirmation, and donor identity verification |
US7879623B2 (en) * | 2006-03-31 | 2011-02-01 | Guirguis Raouf A | Integrated device for analyte, testing, confirmation, and donor identity verification |
US7741103B2 (en) * | 2006-03-31 | 2010-06-22 | Guirguis Raouf A | Integrated screening and confirmation device |
US7569396B1 (en) | 2006-09-08 | 2009-08-04 | Purplecow Llc | Caffeine detection using internally referenced competitive assays |
US7919331B2 (en) * | 2006-12-21 | 2011-04-05 | Silver Lake Research Corporation | Chromatographic test strips for one or more analytes |
JP4870695B2 (ja) * | 2008-02-12 | 2012-02-08 | 富士フイルム株式会社 | メンブレン内の標識を洗浄、増幅、停止する方法 |
JP4980946B2 (ja) * | 2008-02-12 | 2012-07-18 | 富士フイルム株式会社 | ブロッティング検出方法 |
US8673644B2 (en) | 2008-05-13 | 2014-03-18 | Battelle Memorial Institute | Serum markers for type II diabetes mellitus |
US8476008B2 (en) * | 2008-07-23 | 2013-07-02 | Diabetomics, Llc | Methods for detecting pre-diabetes and diabetes |
US20100047913A1 (en) * | 2008-08-19 | 2010-02-25 | The Trustees Of The University Of Pennsylvania | Colloidal Gold Single Reagent Quantitative Protein Assay |
EP2391891A1 (en) | 2009-01-27 | 2011-12-07 | Proteogenix, Inc. | Biomarkers for detection of neonatal sepsis in biological fluid |
US20110275536A1 (en) | 2009-01-30 | 2011-11-10 | Pronota N.V. | Biomarker for diagnosis, prediction and/or prognosis of acute heart failure and uses thereof |
WO2010132447A2 (en) | 2009-05-11 | 2010-11-18 | Diabetomics, Llc | Methods for detecting pre-diabetes and diabetes using differential protein glycosylation |
EP2491401B1 (en) | 2009-10-21 | 2018-06-06 | Mycartis N.V. | Mcam as a biomarker for fluid homeostasis |
ES2677944T3 (es) | 2009-11-25 | 2018-08-07 | Hologic Inc. | Detección de infección intraamniótica |
US20130040881A1 (en) | 2010-03-26 | 2013-02-14 | Pronota N.V. | Ltbp2 as a biomarker for renal dysfunction |
WO2011128357A2 (en) | 2010-04-13 | 2011-10-20 | Pronota N.V. | Biomarkers for hypertensive disorders of pregnancy |
US10670586B2 (en) * | 2010-04-14 | 2020-06-02 | Nitto Boseki Co., Ltd. | Test instrument for measuring analyte in sample by an aggregation assay using a metal colloid and using a reagent attached in a dry state in a reaction chamber, and method for measuring analyte using same |
CA2800257C (en) | 2010-05-26 | 2019-03-05 | The Board Of Trustees Of The University Of Illinois | Personal glucose meters for detection and quantification of a broad range of analytes |
EP2591366A2 (en) | 2010-07-08 | 2013-05-15 | Pronota NV | Quiescin q6 as biomarker for hypertensive disorders of pregnancy |
US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
US20120142559A1 (en) | 2010-12-06 | 2012-06-07 | Pronota N.V. | Biomarkers and parameters for hypertensive disorders of pregnancy |
EP2788371A2 (en) | 2011-12-08 | 2014-10-15 | Biocartis NV | Biomarkers and test panels useful in systemic inflammatory conditions |
IN2014CN04326A (es) | 2011-12-15 | 2015-09-04 | Pronota Nv | |
EP2807271B1 (en) | 2012-01-24 | 2018-08-22 | CD Diagnostics, Inc. | System for detecting infection in synovial fluid |
US20140248629A1 (en) * | 2013-03-03 | 2014-09-04 | Morteza Mahmoudi | Gold nanoparticle based dipstick nano-biosensor for detecting plasmodium falciparum and plasmodium vivax and mehtod of synthesizing the same |
US9383352B2 (en) | 2014-03-26 | 2016-07-05 | Diabetomics, Inc. | Salivary protein glycosylation test for diagnosis and monitoring of diabetes |
GB2552427A (en) | 2015-01-29 | 2018-01-24 | Neogen Corp | Methods for immuno chromatographic assay desensitization |
EP3286216B1 (en) | 2015-04-23 | 2022-06-08 | Nevada Research & Innovation Corporation | Fungal detection using mannan epitope |
CN108136051A (zh) | 2015-08-04 | 2018-06-08 | Cd诊断股份有限公司 | 检测不良局部组织反应(altr)坏死的方法 |
US10151749B2 (en) * | 2015-08-05 | 2018-12-11 | Alfaisal University | Method and kit for the detection of microorganisms |
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Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4115198A (en) * | 1974-02-11 | 1978-09-19 | Coughlin Robert W | Method of immobilization of biologically active organic substances including enzymes |
IL49685A (en) * | 1976-05-31 | 1978-10-31 | Technion Res & Dev Foundation | Specific binding assay method for determining the concentration of materials and reagent means therefor |
US4208185A (en) * | 1976-08-16 | 1980-06-17 | Mitsubishi Chemical Industries Limited | Method and apparatus for the measurement of antigens and antibodies |
US4203724A (en) * | 1976-08-16 | 1980-05-20 | Mitsubishi Chemical Industries Limited | Method and apparatus for the measurement of antigens and antibodies |
SE431257B (sv) * | 1977-11-03 | 1984-01-23 | Du Pont | Sett och anordning for immunanalys med magnetisk metall eller metalloxid som merksubstans |
NL7807532A (nl) * | 1978-07-13 | 1980-01-15 | Akzo Nv | Metaal-immunotest. |
US4420558A (en) * | 1981-02-12 | 1983-12-13 | Janssen Pharmaceutica N.V. | Bright field light microscopic method of enumerating and characterizing subtypes of white blood cells and their precursors |
US4487839A (en) * | 1983-01-05 | 1984-12-11 | Ortho Diagnostic Systems Inc. | Immunoassay methods employing patterns for the detection of soluble and cell surface antigens |
CA1260827A (en) * | 1984-08-31 | 1989-09-26 | Richard C. Siegel | Antibody-metal ion complexes |
-
1983
- 1983-11-25 GB GB838331514A patent/GB8331514D0/en active Pending
-
1984
- 1984-10-31 EP EP84201559A patent/EP0158746B1/en not_active Expired - Lifetime
- 1984-10-31 AT AT84201559T patent/ATE64468T1/de not_active IP Right Cessation
- 1984-10-31 DE DE8484201559T patent/DE3484710D1/de not_active Expired - Lifetime
- 1984-11-07 CA CA000467203A patent/CA1253422A/en not_active Expired
- 1984-11-15 KR KR1019840007168A patent/KR890001131B1/ko not_active IP Right Cessation
- 1984-11-16 FI FI844508A patent/FI80345C/fi active IP Right Grant
- 1984-11-21 JP JP59244692A patent/JPH0643998B2/ja not_active Expired - Lifetime
- 1984-11-22 PT PT79533A patent/PT79533A/pt unknown
- 1984-11-23 ZA ZA849182A patent/ZA849182B/xx unknown
- 1984-11-23 DK DK557684A patent/DK160108C/da not_active IP Right Cessation
- 1984-11-23 AU AU35825/84A patent/AU583484B2/en not_active Expired
- 1984-11-23 IL IL73607A patent/IL73607A/xx not_active IP Right Cessation
- 1984-11-23 NO NO844672A patent/NO163754C/no not_active IP Right Cessation
- 1984-11-23 ES ES537926A patent/ES537926A0/es active Granted
- 1984-11-23 NZ NZ210309A patent/NZ210309A/en unknown
-
1987
- 1987-10-27 US US07/115,652 patent/US4775636A/en not_active Expired - Lifetime
-
1993
- 1993-03-17 JP JP5081149A patent/JP2601616B2/ja not_active Expired - Lifetime
-
1994
- 1994-02-24 HK HK148/94A patent/HK14894A/xx not_active IP Right Cessation
- 1994-07-15 CY CY175994A patent/CY1759A/xx unknown
Also Published As
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---|---|
DK160108C (da) | 1995-07-24 |
NZ210309A (en) | 1987-04-30 |
DK557684D0 (da) | 1984-11-23 |
CA1253422A (en) | 1989-05-02 |
FI80345B (fi) | 1990-01-31 |
JPH0643998B2 (ja) | 1994-06-08 |
KR890001131B1 (ko) | 1989-04-24 |
EP0158746A2 (en) | 1985-10-23 |
DK557684A (da) | 1985-05-26 |
FI844508L (fi) | 1985-05-26 |
NO163754C (no) | 1993-01-12 |
PT79533A (en) | 1984-12-01 |
JPS60185160A (ja) | 1985-09-20 |
ATE64468T1 (de) | 1991-06-15 |
AU3582584A (en) | 1985-05-30 |
ZA849182B (en) | 1986-06-25 |
HK14894A (en) | 1994-03-04 |
EP0158746B1 (en) | 1991-06-12 |
IL73607A0 (en) | 1985-02-28 |
GB8331514D0 (en) | 1984-01-04 |
NO163754B (no) | 1990-04-02 |
DE3484710D1 (de) | 1991-07-18 |
EP0158746A3 (en) | 1987-09-23 |
NO844672L (no) | 1985-05-28 |
US4775636A (en) | 1988-10-04 |
DK160108B (da) | 1991-01-28 |
FI80345C (fi) | 1992-11-16 |
CY1759A (en) | 1994-07-15 |
FI844508A0 (fi) | 1984-11-16 |
ES537926A0 (es) | 1985-11-01 |
KR850003728A (ko) | 1985-06-26 |
JPH0643162A (ja) | 1994-02-18 |
IL73607A (en) | 1988-12-30 |
JP2601616B2 (ja) | 1997-04-16 |
AU583484B2 (en) | 1989-05-04 |
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FD1A | Patent lapsed |
Effective date: 20050627 |