ES8602255A1 - Un procedimiento para detectar y-o determinar un aglomerado formado por reaccion entre un agente de union especifico y la correspondiente sustancia aceptora - Google Patents
Un procedimiento para detectar y-o determinar un aglomerado formado por reaccion entre un agente de union especifico y la correspondiente sustancia aceptoraInfo
- Publication number
- ES8602255A1 ES8602255A1 ES537926A ES537926A ES8602255A1 ES 8602255 A1 ES8602255 A1 ES 8602255A1 ES 537926 A ES537926 A ES 537926A ES 537926 A ES537926 A ES 537926A ES 8602255 A1 ES8602255 A1 ES 8602255A1
- Authority
- ES
- Spain
- Prior art keywords
- reaction
- binding agent
- specific binding
- direct
- acceptor substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000006243 chemical reaction Methods 0.000 title abstract 4
- 239000011230 binding agent Substances 0.000 title abstract 3
- 230000009870 specific binding Effects 0.000 title abstract 3
- 238000003556 assay Methods 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 238000007794 visualization technique Methods 0.000 title 1
- 230000008878 coupling Effects 0.000 abstract 2
- 238000010168 coupling process Methods 0.000 abstract 2
- 238000005859 coupling reaction Methods 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 1
- 239000002923 metal particle Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
- G01N33/559—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody through a gel, e.g. Ouchterlony technique
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Communication Control (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Details Of Television Scanning (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Abstract
METODO PARA LA DETECCION Y/O DETERMINACION EN ENSAYOS DE TRANSFERENCIA POR SUPERPOSICION DE UN AGLOMERADO FORMADO POR UN AGENTE DE UNION Y LA CORRESPONDIENTE SUSTANCIA ACEPTORA. COMPRENDE LAS ETAPAS DE: A) INMOVILIZAR LA SUSTANCIA ACEPTORA SOBRE UNA MATRIZ INMOVILIZANTE, B) PONER EN CONTACTO DICHA MATRIZ INMOVILIZANTE CON UNA PROTEINA DE UNION ESPECIFICA MARCADA CON PARTICULAS METALICAS COLOIDALES; O BIEN CON UNA PROTEINA DE UNION ESPECIFICA NO MARCADA Y POSTERIORMENTE CON UNA PROTEINA MARCADA CON METAL COLOIDAL ESPECIFICA PARA LA PROTEINA NO MARCADA, Y C) DETECTAR LA SEÑAL COLOREADA EN EL SITIO DE REACCION EN LA SUPERFICIE DE LA MATRIZ INMOVILIZANTE DESPUES DE HABER APLICADO UN REVELADOR FISICO QUE CONTIENE PLATA. LAS PARTICULAS METALICAS COLOIDALES ESTAN CONSTITUIDAS POR ORO, PLATA, PLATINO O COMPUESTOS DE ESTOS METALES O COMPUESTOS DE HIERRO O COBRE CON UN TAMAÑO DE PARTICULA COMPRENDIDO ENTRE 3 NM Y 100 NM.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838331514A GB8331514D0 (en) | 1983-11-25 | 1983-11-25 | Visualization method |
Publications (2)
Publication Number | Publication Date |
---|---|
ES537926A0 ES537926A0 (es) | 1985-11-01 |
ES8602255A1 true ES8602255A1 (es) | 1985-11-01 |
Family
ID=10552346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES537926A Expired ES8602255A1 (es) | 1983-11-25 | 1984-11-23 | Un procedimiento para detectar y-o determinar un aglomerado formado por reaccion entre un agente de union especifico y la correspondiente sustancia aceptora |
Country Status (19)
Country | Link |
---|---|
US (1) | US4775636A (es) |
EP (1) | EP0158746B1 (es) |
JP (2) | JPH0643998B2 (es) |
KR (1) | KR890001131B1 (es) |
AT (1) | ATE64468T1 (es) |
AU (1) | AU583484B2 (es) |
CA (1) | CA1253422A (es) |
CY (1) | CY1759A (es) |
DE (1) | DE3484710D1 (es) |
DK (1) | DK160108C (es) |
ES (1) | ES8602255A1 (es) |
FI (1) | FI80345C (es) |
GB (1) | GB8331514D0 (es) |
HK (1) | HK14894A (es) |
IL (1) | IL73607A (es) |
NO (1) | NO163754C (es) |
NZ (1) | NZ210309A (es) |
PT (1) | PT79533A (es) |
ZA (1) | ZA849182B (es) |
Families Citing this family (116)
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Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
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US4115198A (en) * | 1974-02-11 | 1978-09-19 | Coughlin Robert W | Method of immobilization of biologically active organic substances including enzymes |
IL49685A (en) * | 1976-05-31 | 1978-10-31 | Technion Res & Dev Foundation | Specific binding assay method for determining the concentration of materials and reagent means therefor |
US4203724A (en) * | 1976-08-16 | 1980-05-20 | Mitsubishi Chemical Industries Limited | Method and apparatus for the measurement of antigens and antibodies |
US4208185A (en) * | 1976-08-16 | 1980-06-17 | Mitsubishi Chemical Industries Limited | Method and apparatus for the measurement of antigens and antibodies |
SE431257B (sv) * | 1977-11-03 | 1984-01-23 | Du Pont | Sett och anordning for immunanalys med magnetisk metall eller metalloxid som merksubstans |
NL7807532A (nl) * | 1978-07-13 | 1980-01-15 | Akzo Nv | Metaal-immunotest. |
US4420558A (en) * | 1981-02-12 | 1983-12-13 | Janssen Pharmaceutica N.V. | Bright field light microscopic method of enumerating and characterizing subtypes of white blood cells and their precursors |
US4487839A (en) * | 1983-01-05 | 1984-12-11 | Ortho Diagnostic Systems Inc. | Immunoassay methods employing patterns for the detection of soluble and cell surface antigens |
CA1260827A (en) * | 1984-08-31 | 1989-09-26 | Richard C. Siegel | Antibody-metal ion complexes |
-
1983
- 1983-11-25 GB GB838331514A patent/GB8331514D0/en active Pending
-
1984
- 1984-10-31 EP EP84201559A patent/EP0158746B1/en not_active Expired - Lifetime
- 1984-10-31 AT AT84201559T patent/ATE64468T1/de not_active IP Right Cessation
- 1984-10-31 DE DE8484201559T patent/DE3484710D1/de not_active Expired - Lifetime
- 1984-11-07 CA CA000467203A patent/CA1253422A/en not_active Expired
- 1984-11-15 KR KR1019840007168A patent/KR890001131B1/ko not_active IP Right Cessation
- 1984-11-16 FI FI844508A patent/FI80345C/fi active IP Right Grant
- 1984-11-21 JP JP59244692A patent/JPH0643998B2/ja not_active Expired - Lifetime
- 1984-11-22 PT PT79533A patent/PT79533A/pt unknown
- 1984-11-23 DK DK557684A patent/DK160108C/da not_active IP Right Cessation
- 1984-11-23 AU AU35825/84A patent/AU583484B2/en not_active Expired
- 1984-11-23 ZA ZA849182A patent/ZA849182B/xx unknown
- 1984-11-23 ES ES537926A patent/ES8602255A1/es not_active Expired
- 1984-11-23 NO NO844672A patent/NO163754C/no not_active IP Right Cessation
- 1984-11-23 NZ NZ210309A patent/NZ210309A/en unknown
- 1984-11-23 IL IL73607A patent/IL73607A/xx not_active IP Right Cessation
-
1987
- 1987-10-27 US US07/115,652 patent/US4775636A/en not_active Expired - Lifetime
-
1993
- 1993-03-17 JP JP5081149A patent/JP2601616B2/ja not_active Expired - Lifetime
-
1994
- 1994-02-24 HK HK148/94A patent/HK14894A/xx not_active IP Right Cessation
- 1994-07-15 CY CY175994A patent/CY1759A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ZA849182B (en) | 1986-06-25 |
NZ210309A (en) | 1987-04-30 |
DE3484710D1 (de) | 1991-07-18 |
AU3582584A (en) | 1985-05-30 |
FI844508A0 (fi) | 1984-11-16 |
CY1759A (en) | 1994-07-15 |
AU583484B2 (en) | 1989-05-04 |
EP0158746B1 (en) | 1991-06-12 |
JPS60185160A (ja) | 1985-09-20 |
ATE64468T1 (de) | 1991-06-15 |
FI80345B (fi) | 1990-01-31 |
JP2601616B2 (ja) | 1997-04-16 |
NO163754B (no) | 1990-04-02 |
EP0158746A2 (en) | 1985-10-23 |
JPH0643998B2 (ja) | 1994-06-08 |
FI844508L (fi) | 1985-05-26 |
IL73607A (en) | 1988-12-30 |
IL73607A0 (en) | 1985-02-28 |
US4775636A (en) | 1988-10-04 |
NO844672L (no) | 1985-05-28 |
DK557684D0 (da) | 1984-11-23 |
JPH0643162A (ja) | 1994-02-18 |
DK160108C (da) | 1995-07-24 |
GB8331514D0 (en) | 1984-01-04 |
DK557684A (da) | 1985-05-26 |
ES537926A0 (es) | 1985-11-01 |
NO163754C (no) | 1993-01-12 |
FI80345C (fi) | 1992-11-16 |
HK14894A (en) | 1994-03-04 |
KR890001131B1 (ko) | 1989-04-24 |
PT79533A (en) | 1984-12-01 |
CA1253422A (en) | 1989-05-02 |
DK160108B (da) | 1991-01-28 |
KR850003728A (ko) | 1985-06-26 |
EP0158746A3 (en) | 1987-09-23 |
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