ES8406196A1 - Procedimiento de obtencion de una solucion inyectable a base de un complejo mixto de hierro ferrico polinuclear y electroneutro - Google Patents
Procedimiento de obtencion de una solucion inyectable a base de un complejo mixto de hierro ferrico polinuclear y electroneutroInfo
- Publication number
- ES8406196A1 ES8406196A1 ES526481A ES526481A ES8406196A1 ES 8406196 A1 ES8406196 A1 ES 8406196A1 ES 526481 A ES526481 A ES 526481A ES 526481 A ES526481 A ES 526481A ES 8406196 A1 ES8406196 A1 ES 8406196A1
- Authority
- ES
- Spain
- Prior art keywords
- acid
- iii
- iron
- equivalents
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical class [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 6
- 239000002253 acid Substances 0.000 abstract 3
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- 238000001256 steam distillation Methods 0.000 abstract 2
- UOQHWNPVNXSDDO-UHFFFAOYSA-N 3-bromoimidazo[1,2-a]pyridine-6-carbonitrile Chemical compound C1=CC(C#N)=CN2C(Br)=CN=C21 UOQHWNPVNXSDDO-UHFFFAOYSA-N 0.000 abstract 1
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 abstract 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- JYTUSYBCFIZPBE-UHFFFAOYSA-N Maltobionic acid Natural products OC(=O)C(O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O JYTUSYBCFIZPBE-UHFFFAOYSA-N 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- MSNWSDPPULHLDL-UHFFFAOYSA-K ferric hydroxide Chemical compound [OH-].[OH-].[OH-].[Fe+3] MSNWSDPPULHLDL-UHFFFAOYSA-K 0.000 abstract 1
- 239000000174 gluconic acid Substances 0.000 abstract 1
- 235000012208 gluconic acid Nutrition 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- PVFSDGKDKFSOTB-UHFFFAOYSA-K iron(3+);triacetate Chemical compound [Fe+3].CC([O-])=O.CC([O-])=O.CC([O-])=O PVFSDGKDKFSOTB-UHFFFAOYSA-K 0.000 abstract 1
- JYTUSYBCFIZPBE-AMTLMPIISA-N lactobionic acid Chemical compound OC(=O)[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O JYTUSYBCFIZPBE-AMTLMPIISA-N 0.000 abstract 1
- 229940099563 lactobionic acid Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- 238000005292 vacuum distillation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU823281A HU187167B (en) | 1982-10-15 | 1982-10-15 | Process for producing pharmaceutical solution of new type polynuclear iron/iii/ mixed complex activity |
Publications (2)
Publication Number | Publication Date |
---|---|
ES526481A0 ES526481A0 (es) | 1984-08-01 |
ES8406196A1 true ES8406196A1 (es) | 1984-08-01 |
Family
ID=10963435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES526481A Expired ES8406196A1 (es) | 1982-10-15 | 1983-10-14 | Procedimiento de obtencion de una solucion inyectable a base de un complejo mixto de hierro ferrico polinuclear y electroneutro |
Country Status (11)
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3728814A1 (de) * | 1987-08-28 | 1989-03-30 | Lentia Gmbh | Loesung zur anwendung als spuelfluessigkeit in der zerstoerung von koerperfremden ablagerungen in menschlichen und tierischen geweben oder koerperhohlraeumen |
DE4445772A1 (de) * | 1993-12-27 | 1995-06-29 | Loeser Thomas Dr Ing | Verfahren zur Ermittlung der Arzneimittelzusammensetzung |
DE19712493A1 (de) * | 1997-03-25 | 1998-10-01 | Univ Karlsruhe | Pharmazeutische Zubereitung, enthaltend eine Eisen-Calcium-Polyolato-Verbindung und deren Verwendung |
DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
US20040170724A1 (en) * | 2003-02-28 | 2004-09-02 | Kraft Foods Holdings, Inc. | Mineral complexes of lactobionic acid and method of using for mineral fortification of food products |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE862482C (de) * | 1950-05-14 | 1953-01-12 | Merck Chem Fab E | Verfahren zur Darstellung haltbarer, injizierbarer Loesungen von Salzen des dreiwertigen Eisens |
DE938502C (de) * | 1953-02-27 | 1956-02-02 | Benger S Ltd | Verfahren zur Herstellung einer kolloidalen Eisenzubereitung |
GB978485A (en) * | 1960-10-26 | 1964-12-23 | Astra Apotekarnes Kem Fab | Iron preparations for intramuscular injection |
DE1293144B (de) * | 1964-11-04 | 1969-04-24 | Hausmann Ag Labor | Verfahren zur Herstellung von Komplexverbindungen des Eisens mit Sorbit, Gluconsaeure und einem Oligosaccharid |
DK122890B (da) * | 1964-12-29 | 1972-04-24 | J Reumert | Fremgangsmåde til fremstilling af ferrihydroxiddextrankomplekser. |
DE1617463A1 (de) * | 1965-11-20 | 1971-04-08 | Bayer Ag | Verfahren zur Herstellung von injizierbaren kolloidalen Eisenzubereitungen |
GB1149137A (en) * | 1966-10-28 | 1969-04-16 | H C F Porsche K G Ing | Screw outboard drive for boats |
AT279048B (de) * | 1967-07-04 | 1970-02-25 | Pharmazeutische Fabrik Montavit Gmbh | Verfahren zur Herstellung neuer, löslicher und stabiler organischer Eisen(III)-Komplexverbindungen und Injektionslösungen davon |
DE2527158A1 (de) * | 1975-06-18 | 1976-12-23 | Herz Eberhard | Arzneimittel zur behandlung von infektionskrankheiten und von nicht nachweisbar durch mikroorganismen ausgeloeste entzuendungen in der human- und veterinaermedizin |
JPS6039681B2 (ja) * | 1976-01-01 | 1985-09-07 | 日本臓器製薬株式会社 | デキストリン・クエン酸・第二鉄多核複合体及び該複合体を含有する非経口用鉄剤 |
GB2006243B (en) * | 1977-09-29 | 1982-07-14 | Atomic Energy Authority Uk | Compounds |
DE3026868C2 (de) * | 1980-07-16 | 1986-03-13 | Laboratorien Hausmann AG, St. Gallen | Verfahren zur Herstellung von Eisen(III)hydroxid-Dextran-Komplexen und sie enthaltende pharmazeutische sterile wäßrige Lösung |
-
1982
- 1982-10-15 HU HU823281A patent/HU187167B/hu not_active IP Right Cessation
-
1983
- 1983-10-12 FI FI833707A patent/FI80830C/fi not_active IP Right Cessation
- 1983-10-12 AT AT0363983A patent/AT385655B/de not_active IP Right Cessation
- 1983-10-13 BE BE0/211691A patent/BE897980A/fr not_active IP Right Cessation
- 1983-10-14 ES ES526481A patent/ES8406196A1/es not_active Expired
- 1983-10-14 DK DK476583A patent/DK476583A/da not_active Application Discontinuation
- 1983-10-14 FR FR8316377A patent/FR2534589B1/fr not_active Expired
- 1983-10-14 GB GB08327633A patent/GB2129821B/en not_active Expired
- 1983-10-14 SE SE8305665A patent/SE462140B/sv not_active IP Right Cessation
- 1983-10-14 BG BG062649A patent/BG49708A3/xx unknown
- 1983-10-14 DE DE19833337506 patent/DE3337506A1/de active Granted
Also Published As
Publication number | Publication date |
---|---|
SE8305665D0 (sv) | 1983-10-14 |
FI80830C (fi) | 1990-08-10 |
BE897980A (fr) | 1984-01-30 |
ES526481A0 (es) | 1984-08-01 |
FR2534589B1 (fr) | 1988-12-16 |
FI833707A0 (fi) | 1983-10-12 |
GB2129821A (en) | 1984-05-23 |
GB8327633D0 (en) | 1983-11-16 |
ATA363983A (de) | 1987-10-15 |
FI80830B (fi) | 1990-04-30 |
DE3337506C2 (enrdf_load_stackoverflow) | 1991-07-04 |
BG49708A3 (bg) | 1992-01-15 |
DE3337506A1 (de) | 1984-04-19 |
DK476583A (da) | 1984-04-16 |
AT385655B (de) | 1988-05-10 |
DK476583D0 (da) | 1983-10-14 |
FI833707L (fi) | 1984-04-16 |
GB2129821B (en) | 1986-02-19 |
HU187167B (en) | 1985-11-28 |
SE8305665L (sv) | 1984-04-16 |
FR2534589A1 (fr) | 1984-04-20 |
SE462140B (sv) | 1990-05-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |
Effective date: 19960506 |