ES8105691A1 - Procedimiento para separar d-acido 2-(6-metoxi-2-naftil)- propionico de una mezcla de d-y 1-acidos 2-(6-metoxi-2-naf- til)-propionicos o sus sales - Google Patents

Procedimiento para separar d-acido 2-(6-metoxi-2-naftil)- propionico de una mezcla de d-y 1-acidos 2-(6-metoxi-2-naf- til)-propionicos o sus sales

Info

Publication number
ES8105691A1
ES8105691A1 ES493126A ES493126A ES8105691A1 ES 8105691 A1 ES8105691 A1 ES 8105691A1 ES 493126 A ES493126 A ES 493126A ES 493126 A ES493126 A ES 493126A ES 8105691 A1 ES8105691 A1 ES 8105691A1
Authority
ES
Spain
Prior art keywords
acid
salts
glucamine
propionic
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493126A
Other languages
English (en)
Spanish (es)
Other versions
ES493126A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26734026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8105691(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/097,118 external-priority patent/US4246193A/en
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Publication of ES493126A0 publication Critical patent/ES493126A0/es
Publication of ES8105691A1 publication Critical patent/ES8105691A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/50Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/487Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES493126A 1979-07-06 1980-07-04 Procedimiento para separar d-acido 2-(6-metoxi-2-naftil)- propionico de una mezcla de d-y 1-acidos 2-(6-metoxi-2-naf- til)-propionicos o sus sales Expired ES8105691A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5525879A 1979-07-06 1979-07-06
US06/097,118 US4246193A (en) 1979-11-26 1979-11-26 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Publications (2)

Publication Number Publication Date
ES493126A0 ES493126A0 (es) 1981-06-16
ES8105691A1 true ES8105691A1 (es) 1981-06-16

Family

ID=26734026

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493126A Expired ES8105691A1 (es) 1979-07-06 1980-07-04 Procedimiento para separar d-acido 2-(6-metoxi-2-naftil)- propionico de una mezcla de d-y 1-acidos 2-(6-metoxi-2-naf- til)-propionicos o sus sales

Country Status (27)

Country Link
EP (1) EP0022529B1 (cg-RX-API-DMAC10.html)
JP (2) JPS63313749A (cg-RX-API-DMAC10.html)
KR (1) KR830000769B1 (cg-RX-API-DMAC10.html)
AR (1) AR225927A1 (cg-RX-API-DMAC10.html)
AU (1) AU544963B2 (cg-RX-API-DMAC10.html)
CA (1) CA1135717A (cg-RX-API-DMAC10.html)
CZ (1) CZ277725B6 (cg-RX-API-DMAC10.html)
DD (1) DD153367A5 (cg-RX-API-DMAC10.html)
DE (3) DE3051036C2 (cg-RX-API-DMAC10.html)
DK (2) DK156051C (cg-RX-API-DMAC10.html)
ES (1) ES8105691A1 (cg-RX-API-DMAC10.html)
FR (2) FR2472557A1 (cg-RX-API-DMAC10.html)
GB (1) GB2054579B (cg-RX-API-DMAC10.html)
GR (1) GR68796B (cg-RX-API-DMAC10.html)
HK (1) HK886A (cg-RX-API-DMAC10.html)
IE (1) IE50000B1 (cg-RX-API-DMAC10.html)
IL (1) IL60498A (cg-RX-API-DMAC10.html)
IN (1) IN152737B (cg-RX-API-DMAC10.html)
IT (1) IT1130490B (cg-RX-API-DMAC10.html)
MY (1) MY8600452A (cg-RX-API-DMAC10.html)
NZ (1) NZ194237A (cg-RX-API-DMAC10.html)
PH (4) PH15674A (cg-RX-API-DMAC10.html)
PL (1) PL133439B1 (cg-RX-API-DMAC10.html)
PT (1) PT71486A (cg-RX-API-DMAC10.html)
RO (1) RO80655B (cg-RX-API-DMAC10.html)
SK (1) SK278340B6 (cg-RX-API-DMAC10.html)
YU (1) YU42673B (cg-RX-API-DMAC10.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168387B (it) * 1981-04-01 1987-05-20 Alfa Farmaceutici Spa Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico
ZA828453B (en) * 1981-12-08 1983-12-28 Boots Co Plc Therapeutic agents
IT1196197B (it) * 1984-07-23 1988-11-10 Ravizza Spa Procedimento per la risoluzione dell'acido (+)(-) 2-(2'-(p-fluorofenil)--5'-benzossazolil)-propionico
GB9121279D0 (en) * 1991-10-08 1991-11-20 Cerestar Holding Bv Process for the production of aminopolyols
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
KR100678287B1 (ko) * 2005-06-23 2007-02-02 한미약품 주식회사 클로피도그렐의 제조방법 및 이에 사용되는 중간체
KR101170537B1 (ko) * 2010-01-11 2012-08-01 김창운 해수의 자연순환이 가능한 내륙 내 바다양식 수조

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
DE1668654B2 (de) * 1967-01-13 1976-11-04 Syntex Corp., Panama 2-(6'-substituierte-2'-naphthyl)- propionsaeuren und -derivate, ihre herstellung und sie enthaltende arzneimittel
ZA70809B (en) * 1969-03-24 1971-09-29 Syntex Corp Amine salts of 2-(6'-methoxy-2'-naphthyl)propionic acids and processes for the preparation thereof
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
US3904683A (en) * 1972-08-10 1975-09-09 Syntex Corp Process for the resolution of d- and 1-2-(6-methoxy-2-naphthyl) propionic acid
CS222255B2 (en) * 1977-03-08 1983-06-24 Boots Co Ltd Method of increasing the portion of the deisred anantiometer in the acid component of the 2-arylpropion acid
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.

Also Published As

Publication number Publication date
ES493126A0 (es) 1981-06-16
IN152737B (cg-RX-API-DMAC10.html) 1984-03-24
RO80655A (ro) 1983-04-29
CS477480A3 (en) 1992-11-18
YU42673B (en) 1988-10-31
IT8068053A0 (it) 1980-07-03
GB2054579B (en) 1983-06-22
IE801396L (en) 1981-01-06
CZ277725B6 (en) 1993-04-14
KR830000769B1 (ko) 1983-04-11
DK156051C (da) 1989-11-06
FR2470108A1 (fr) 1981-05-29
IL60498A (en) 1984-06-29
CA1135717A (en) 1982-11-16
AU6012180A (en) 1981-01-15
PH16432A (en) 1983-10-03
DK289080A (da) 1981-01-07
GR68796B (cg-RX-API-DMAC10.html) 1982-02-18
IL60498A0 (en) 1980-09-16
DE3025448C2 (cg-RX-API-DMAC10.html) 1987-05-21
IT1130490B (it) 1986-06-11
IE50000B1 (en) 1986-01-22
DE3063969D1 (en) 1983-08-04
AU544963B2 (en) 1985-06-27
PH16328A (en) 1983-09-05
RO80655B (ro) 1983-04-30
DK156051B (da) 1989-06-19
DK239988D0 (da) 1988-05-03
PL133439B1 (en) 1985-06-29
JPH0454B2 (cg-RX-API-DMAC10.html) 1992-01-06
PT71486A (en) 1980-08-01
FR2470108B1 (cg-RX-API-DMAC10.html) 1984-04-20
JPH0321535B2 (cg-RX-API-DMAC10.html) 1991-03-22
EP0022529B1 (en) 1983-06-29
EP0022529A1 (en) 1981-01-21
DD153367A5 (de) 1982-01-06
GB2054579A (en) 1981-02-18
JPS63313749A (ja) 1988-12-21
AR225927A1 (es) 1982-05-14
NZ194237A (en) 1984-05-31
DE3025448A1 (de) 1981-01-15
FR2472557B1 (cg-RX-API-DMAC10.html) 1984-04-20
PH16431A (en) 1983-10-03
YU174380A (en) 1984-04-30
HK886A (en) 1986-01-10
DE3051036C2 (cg-RX-API-DMAC10.html) 1988-03-31
SK278340B6 (en) 1996-12-04
PH15674A (en) 1983-03-11
DK239988A (da) 1988-05-03
MY8600452A (en) 1986-12-31
FR2472557A1 (fr) 1981-07-03
JPH0249749A (ja) 1990-02-20
PL225474A1 (cg-RX-API-DMAC10.html) 1981-03-27

Similar Documents

Publication Publication Date Title
AR227864A1 (es) Procedimiento para obtener isomeros syn de compuestos del acido 3-cefem-4-carboxilicos 3,7 disustituidos
AR228957A1 (es) Procedimiento para obtener compuestos del acido 1-bencil-4-halo-imidazol-5-acetico y de sus sales y procedimiento para preparar composiciones farmaceuticas que incluyen a dichos compuestos del acido 1-bencil-4-haloimidazol-5-acetico,como agente activo
MX158337A (es) Procedimiento para preparar derivados del acido 7-acilamino-3-vinil-cefalosporanico
AR222966A1 (es) Nuevos derivados del acido 4-oxifenoxialcancarboxilico,heterociclicamente substituidos,un procedimiento para su obtencion y composiciones que los contienen
MX5299E (es) Procedimiento para transformar un ester de acido quiral de alcohol secundario alfa-cianado opticamente activo de estructura(r) o racemico(r,s)en un ester de acido quiral de alcohol secundario alfa-cianado opticamente activo de estructura(s)
AR212010A1 (es) Procedimiento para preparar nuevos compuestos derivados del acido 2-(p-clorofenil)-5-benzoxazolil acetico o propionico,particularmente utiles como agentes activos analgesicos,antipireticos,antiinflamatorios,asi como tamblen inhibidores de la sintesis o liberacion de prostaglandina
ES8105691A1 (es) Procedimiento para separar d-acido 2-(6-metoxi-2-naftil)- propionico de una mezcla de d-y 1-acidos 2-(6-metoxi-2-naf- til)-propionicos o sus sales
ES494808A0 (es) Un procedimiento para preparar una solucion oftalmica que contiene una sal de 2-acetil-7-(2-hidroxi-3-isopropilamino- propoxi) benzofurano.
AR216496A1 (es) Procedimiento para preparar derivados del acido n-(benzotiazol-2-il)-oxamidico
AR203164A1 (es) Procedimiento para preparar derivados del acido 2-(1-piperazinil)-5,8-dihidro-5-oxopirido <2,3-d> pirimidin-5-carbocilico
SE8206984D0 (sv) Terapeutiskt medel
AR222311A1 (es) Procedimiento para preparar derivados de 1,2,3,3 alpha,8,8 alpha,hexahidropirrol-(2,3-b)indol y sus sales
AR231536A1 (es) Procedimiento para la elaboracion de derivados del acido 5-o 6-alcanoil-,5-o 6-cicloalcanoil- y 5-o 6-benzoil-benzimidazol-2-carboxilico
ES8605276A1 (es) Procedimiento de preparar derivados de penicilina
AR214651A1 (es) Procedimiento para preparar nuevos derivados de coenzima b12
AR224011A1 (es) Procedimiento para preparar nuevas 17 beta-n,n-dietilcarbamoil-4-metil-4-aza-5 alfa-androstan-3-onas utiles como inhibidores de 5 alfa-reductasa
AR227452A1 (es) Procedimiento para preparar compuestos del acido 7-(6-fenil-1,2-dihidro-2-oxopiridina-3-carbonilamino)-fenilacetamino-3-metil-3-cefem-4-carboxilico y sus sales
ES473069A1 (es) Procedimiento para la obtencion de pantoato de guanidina op-ticamente activo
ES493329A0 (es) Procedimiento para la obtencion de esteres del acido n,n-di-metil-o-pirimidinil-carbamico,de efecto pesticida
ES494479A0 (es) Procedimiento para preparar derivados del acido 7-amino-ce- falosporanico
IT1059414B (it) Procedimento per produrre soluzio ni di acido per propionico
AR201046A1 (es) Procedimiento para la obtencion de nuevos derivados de 1,1a,6,10b-tetrahidro - 1,6-metano - dibenzo <a,e)ciclopropa<c>ciclohepteno
ES8700226A1 (es) Un procedimiento para la preparacion en forma cristalina de una mezcla de sales diastereomericas del ester 1-pivaloiloxietilico de (s)-3-(3,4-dihidroxifenil)-2-metilalanina
ES476405A1 (es) Un metodo para la preparacion de 2-metiltio-6-fluoro-9-(1- metil-4-piperilideno)-tioxanteno
ES8302458A1 (es) Procedimiento para preparar nuevas 1-substituido-6-n-propil-8-metilimidazo (1,5-d)-as-triazin-4(3h)-onas.