ES8302458A1 - Procedimiento para preparar nuevas 1-substituido-6-n-propil-8-metilimidazo (1,5-d)-as-triazin-4(3h)-onas. - Google Patents

Procedimiento para preparar nuevas 1-substituido-6-n-propil-8-metilimidazo (1,5-d)-as-triazin-4(3h)-onas.

Info

Publication number
ES8302458A1
ES8302458A1 ES509298A ES509298A ES8302458A1 ES 8302458 A1 ES8302458 A1 ES 8302458A1 ES 509298 A ES509298 A ES 509298A ES 509298 A ES509298 A ES 509298A ES 8302458 A1 ES8302458 A1 ES 8302458A1
Authority
ES
Spain
Prior art keywords
methylimidazo
triazin
propyl
ones
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES509298A
Other languages
English (en)
Other versions
ES509298A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES509298A0 publication Critical patent/ES509298A0/es
Publication of ES8302458A1 publication Critical patent/ES8302458A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR NUEVAS 1-SUBSTITUIDO-6-<004>N<005>-PROPIL-8-METILIMIDAZO<014>1,5-D<015>-AS- -TRIAZIN-4(3H)-ONAS. CONSISTE EN CICLIZAR EL COMPUESTO DE FORMULA GENERAL (I) EN ETER DIFENILICO A UNA TEMPERATURA DE 150<025>C A 250<025>C DURANTE UN TIEMPO DE 15 A 45 MINUTOS. SE OBTIENE EL COMPUESTO (II) DEL QUE PUEDEN OBTENERSE LAS SALES DE ADICION FARMACEUTICAMENTE ACEPTABLES. R ES METILO, ETILO O N-PROPILO. ACTIVIDAD ANTI-ASMATICA.
ES509298A 1981-02-04 1982-02-03 Procedimiento para preparar nuevas 1-substituido-6-n-propil-8-metilimidazo (1,5-d)-as-triazin-4(3h)-onas. Expired ES8302458A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/231,196 US4447603A (en) 1981-02-04 1981-02-04 Substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4-(3H)-ones

Publications (2)

Publication Number Publication Date
ES509298A0 ES509298A0 (es) 1982-12-16
ES8302458A1 true ES8302458A1 (es) 1982-12-16

Family

ID=22868148

Family Applications (1)

Application Number Title Priority Date Filing Date
ES509298A Expired ES8302458A1 (es) 1981-02-04 1982-02-03 Procedimiento para preparar nuevas 1-substituido-6-n-propil-8-metilimidazo (1,5-d)-as-triazin-4(3h)-onas.

Country Status (19)

Country Link
US (1) US4447603A (es)
EP (1) EP0057289A1 (es)
JP (1) JPS57146781A (es)
KR (1) KR830009101A (es)
AR (1) AR227703A1 (es)
AU (1) AU8015682A (es)
CA (1) CA1156230A (es)
DD (1) DD201596A5 (es)
DE (1) DE3202366A1 (es)
DK (1) DK46982A (es)
ES (1) ES8302458A1 (es)
FI (1) FI820341L (es)
GR (1) GR75170B (es)
IE (1) IE820237L (es)
IL (1) IL64646A0 (es)
NO (1) NO820320L (es)
PL (1) PL234938A1 (es)
PT (1) PT74374B (es)
ZA (1) ZA82698B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0085756A1 (en) * 1982-02-10 1983-08-17 American Cyanamid Company Process for preparing 1-substituted-6-n-propyl-8-methylimidazo(1,5-d)-as-triazin-4(3H)-ones
CA2163399A1 (en) * 1994-11-24 1996-05-25 Katsuhiro Kawano Triazine derivative, chymase activity inhibitor and nitric oxide production inhibitor
EP2550374A1 (en) 2010-03-23 2013-01-30 Siemens Aktiengesellschaft Metallic bondcoat or alloy with a high / ' transition temperature and a component

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107307A (en) * 1977-02-03 1978-08-15 American Cyanamid Company Imidazo [1,5-d]-as-triazine-4(3H)-ones and thiones
US4115572A (en) * 1977-02-03 1978-09-19 American Cyanamid Company Imidazo-[1,5-d]-as-triazin-1(2H)-ones and method of ameliorating asthma
US4096257A (en) * 1977-05-23 1978-06-20 American Cyanamid Company Substituted imidazo [1,2-d]-as-triazines
US4107308A (en) * 1977-10-18 1978-08-15 American Cyanamid Company Imidazo[1,5-d]-as-triazines

Also Published As

Publication number Publication date
GR75170B (es) 1984-07-13
EP0057289A1 (en) 1982-08-11
AR227703A1 (es) 1982-11-30
US4447603A (en) 1984-05-08
DK46982A (da) 1982-08-05
PT74374A (en) 1982-03-01
ES509298A0 (es) 1982-12-16
IE820237L (en) 1982-08-04
NO820320L (no) 1982-08-05
KR830009101A (ko) 1983-12-17
FI820341L (fi) 1982-08-05
ZA82698B (en) 1983-01-26
DD201596A5 (de) 1983-07-27
PT74374B (en) 1983-08-24
CA1156230A (en) 1983-11-01
AU8015682A (en) 1982-08-12
DE3202366A1 (de) 1982-09-23
JPS57146781A (en) 1982-09-10
PL234938A1 (en) 1983-01-31
IL64646A0 (en) 1982-03-31

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