ES8101082A1 - Procedimiento para la preparacion de 6b. 7b; 15.16-dimeti- len 1,4-androstadien-3-onas - Google Patents

Procedimiento para la preparacion de 6b. 7b; 15.16-dimeti- len 1,4-androstadien-3-onas

Info

Publication number
ES8101082A1
ES8101082A1 ES491916A ES491916A ES8101082A1 ES 8101082 A1 ES8101082 A1 ES 8101082A1 ES 491916 A ES491916 A ES 491916A ES 491916 A ES491916 A ES 491916A ES 8101082 A1 ES8101082 A1 ES 8101082A1
Authority
ES
Spain
Prior art keywords
onas
translation
procedure
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491916A
Other languages
English (en)
Other versions
ES491916A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of ES491916A0 publication Critical patent/ES491916A0/es
Publication of ES8101082A1 publication Critical patent/ES8101082A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Control Of High-Frequency Heating Circuits (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE 6 7; 15 16-DIMETILEN-1,4-ANDOSTADIEN-3-ONAS. CONSISTE EN INTRODUCIR EL DOBLE ENLACE EN 6BETA 7BETA; 15 16-DIMETILEN-4-ANDROSTAN-3-ONAS, POR VIA QUIMICA O MICROBIOLOGICA. COMO EN ENTES DE DESHIDRATACION QUIMICA PUEDEN EMPLEARSE DIOXIDO DE SELENIO, 2,3-DICLORO-5,6-DICIANOBENZOANINONA, CLORANILO, TRIACETATO DE TALIO O TETRACETATO DE PLOMO. COMO MICROORGANISMO, PUEDEN EMPLEARSE ESQUIZOMICETOS; BACILUS; PSEUDOMONAS, PLAYOBACTERIUM; LACTO-BACILLUS O NOCARDIA. CUANDO SE EMPLEA LA VIA QUIMICA, SE CALIENTA EL 1,2-DIHIDRO-ESTEROIDE DURANTE LARGO TIEMPO CON UN AGENTE DE DESHIDROGENACION EN UN DISOLVENTE TAL COMO DIOXANO, BUTANOL, TETRAHIDROFURANO, TOLUENO, BENCENO, O MEZCLAS DE ESTOS. DIURETICOS.
ES491916A 1979-05-31 1980-05-28 Procedimiento para la preparacion de 6b. 7b; 15.16-dimeti- len 1,4-androstadien-3-onas Expired ES8101082A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792922500 DE2922500A1 (de) 1979-05-31 1979-05-31 6 beta .7 beta

Publications (2)

Publication Number Publication Date
ES491916A0 ES491916A0 (es) 1980-12-16
ES8101082A1 true ES8101082A1 (es) 1980-12-16

Family

ID=6072347

Family Applications (1)

Application Number Title Priority Date Filing Date
ES491916A Expired ES8101082A1 (es) 1979-05-31 1980-05-28 Procedimiento para la preparacion de 6b. 7b; 15.16-dimeti- len 1,4-androstadien-3-onas

Country Status (16)

Country Link
US (1) US4291029A (es)
EP (1) EP0019690B1 (es)
JP (1) JPS55162799A (es)
AT (1) ATE880T1 (es)
AU (1) AU531057B2 (es)
CA (1) CA1134814A (es)
CS (1) CS214712B2 (es)
DD (1) DD151172A5 (es)
DE (2) DE2922500A1 (es)
DK (1) DK145140C (es)
ES (1) ES8101082A1 (es)
HU (2) HU181714B (es)
IE (1) IE49899B1 (es)
IL (1) IL60185A (es)
SU (1) SU873890A3 (es)
YU (1) YU41926B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3111951A1 (de) * 1981-03-23 1982-09-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen 7(alpha)-alkoxycarbonyl-15ss-methylen-4-androstene, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE3213962A1 (de) * 1982-04-13 1983-10-13 Schering AG, 1000 Berlin und 4709 Bergkamen 1(alpha).2(alpha);6(beta).7(beta).15(beta).16(beta)-trimethylen-3-oxo-17(alpha)-pregn-4-en-21.17-carbolacton, dessen herstellung und verwendung als arzneimittel
DE3222265A1 (de) * 1982-06-09 1983-12-15 Schering AG, 1000 Berlin und 4709 Bergkamen 6ss.7ss-methylen-17(alpha)-pregn-4-en-21.17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel
JPS5921698A (ja) * 1982-07-22 1984-02-03 シエ−リング・アクチエンゲゼルシヤフト １７α−プレグネ−４−エン−３−オキソ−２１−カルボン酸エステル、その製法およびこれを含有する抗アンドロゲン作用を有する医薬
DE3227598A1 (de) * 1982-07-22 1984-01-26 Schering AG, 1000 Berlin und 4709 Bergkamen 7(alpha)-acylthio-15.16-methylen-3-oxo-17(alpha)-pregna-1.4-dien-21,17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE3240510A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 7(alpha)-acylthio-1(alpha),2(alpha)-methylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, deren herstellung und diese enthaltende arzneimittel
FI77669C (fi) * 1983-04-13 1989-04-10 Ciba Geigy Ag 20-spiroxaner och analoger, som innehaoller en oeppen ring e, foerfarande foer deras framstaellning samt dessa innehaollande farmaceutiska preparat.
DE3326013A1 (de) * 1983-07-15 1985-01-24 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-methylen-17(alpha)-pregna-4,6-dien-21-carbonsaeuresalze, diese enthaltende pharmazeutische praeparate sowie verfahren zu deren herstellung
EP0134529B1 (de) * 1983-08-17 1990-03-21 Schering Aktiengesellschaft 7-alpha-Substituierte 3-Oxo-17alpha-pregn-4-en-21.17-carbolactone, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3410880A1 (de) * 1984-03-21 1985-10-03 Schering AG, Berlin und Bergkamen, 1000 Berlin 17-substituierte estradiene und estratriene
FR2697328A1 (fr) * 1992-10-23 1994-04-29 Giat Ind Sa Munition fumigène.
US6787531B1 (en) * 1999-08-31 2004-09-07 Schering Ag Pharmaceutical composition for use as a contraceptive
US20020132801A1 (en) * 2001-01-11 2002-09-19 Schering Aktiengesellschaft Drospirenone for hormone replacement therapy
DE102007027636A1 (de) 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-18a-homo-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007027637A1 (de) 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007027635A1 (de) 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-19-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063500A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 17-(1'-Propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063499A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft Steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063501A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15, 16-Methylen-17-hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063495A1 (de) 2007-12-29 2009-09-17 Bayer Schering Pharma Aktiengesellschaft 19-Nor-Steroidderivate mit einer 15α,16α-Methylengruppe und einem gesättigten 17,17-Spirolactonring, deren Verwendung sowie diese Derivate enthaltende Arzneimittel
DE102007063498A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15,16-Methylen-steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063503A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063496A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15,16-Methylen-17-(1'-propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102008026793A1 (de) 2008-06-02 2009-12-03 Bayer Schering Pharma Aktiengesellschaft C-Ring-substituierte Pregn-4-en-21,17-carbolactone, sowie diese enthaltende pharmazeutische Präparate
MX2014005367A (es) 2011-11-04 2014-07-09 Bayer Pharma AG 18-metil-6,7-metilen-3-oxo-17-pregn-4-en-21,17b-carbolactona, preparados farmaceuticos que contienen los compuestos mencionados y su uso en la terapia de la endometriosis.
WO2016063269A1 (en) 2014-10-20 2016-04-28 Prendergast Patrick T Use of antagonists to the nuclear steroid receptor alone or in combination as direct antiviral agents to inhibit alphavirus, togaviridae, arenaviridae, filoviridae, bunyaviridae, flaviviridae and rhabdoviridae

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3254074A (en) * 1962-04-25 1966-05-31 Merck & Co Inc Spiroxenones
DE2264189C3 (de) * 1972-12-29 1979-05-31 Merck & Co., Inc., Rahway, N.J. (V.St.A.) 3'-(3-Oxo-17beta-hydroxy-6,7-methylen-androst-4en-bzw.-l,4-dien-17 a-yl) -propionsäureverbindungen, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel
DE2652761C2 (de) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
ES469510A1 (es) * 1977-05-16 1978-12-01 Schering Ag Procedimiento para la preparacion de 17beta hidroxi-4-an- drosten-3-onas.

Also Published As

Publication number Publication date
YU132980A (en) 1983-02-28
DK145140C (da) 1983-02-21
EP0019690A1 (de) 1980-12-10
IE801127L (en) 1980-11-30
DE2922500A1 (de) 1980-12-04
CA1134814A (en) 1982-11-02
US4291029A (en) 1981-09-22
ES491916A0 (es) 1980-12-16
HU187419B (en) 1986-01-28
JPS55162799A (en) 1980-12-18
DK145140B (da) 1982-09-13
HU181714B (en) 1983-11-28
DD151172A5 (de) 1981-10-08
DE3060297D1 (en) 1982-06-03
IL60185A0 (en) 1980-07-31
ATE880T1 (de) 1982-05-15
YU41926B (en) 1988-02-29
EP0019690B1 (de) 1982-04-21
AU531057B2 (en) 1983-08-11
IL60185A (en) 1983-06-15
SU873890A3 (ru) 1981-10-15
JPH0214360B2 (es) 1990-04-06
IE49899B1 (en) 1986-01-08
AU5874580A (en) 1980-12-04
DK234780A (da) 1980-12-01
CS214712B2 (en) 1982-05-28

Similar Documents

Publication Publication Date Title
ES8101082A1 (es) Procedimiento para la preparacion de 6b. 7b; 15.16-dimeti- len 1,4-androstadien-3-onas
KR840004511A (ko) 세스키테르펜 락톤 화합물의 제조방법
ES432181A1 (es) Procedimiento para la obtencion de la sustancia antibioticalipiarmicina.
ES460385A1 (es) Un procedimiento para preparar una 6a,10a-trans-hexahidrodi-benzo (b,d) piran-9-ona.
ES471440A1 (es) Procedimiento para preparar una composicion de polimero re- sinoso con elevada resistencia a los impactos
ES2025663T3 (es) Composiciones inoculantes para plantas.
KR830004801A (ko) 분산가능한 크산탄검 조성물
KR890014018A (ko) 디프룩토스 디안히드리드 iii의 제조방법
ES444656A1 (es) Procedimiento para preparar una composicion de ensimaje.
GB1393086A (en) Palladium on silica catalyst
KR850005836A (ko) 3-위치가 치환된 2(3h)-벤즈티아졸론의 제조방법
KR840004886A (ko) 가로 연조된 폴리에스테르 필림의 세로연조 방법 및 그에 따라 얻어진 필름
KR840008644A (ko) 원예재배용 클로레라 비료의 제조방법
ES419574A1 (es) Procedimiento para la produccion de agentes antibacteria- nos.
GB919989A (en) Improvements in control knobs for rotatable members
ES311095A1 (es) Un procedimiento para impregnar particulas de polimeros de estireno con un agente de hinchamiento.
KR880002780A (ko) 퇴비의 제조방법
KR920009957A (ko) 가연성 쓰레기를 이용한 고체연료
KR880002975A (ko) P형 액정조성물
KR900014097A (ko) 폐유리섬유와 폐유기섬유를 이용한 건축용판넬의 제조방법
AU218594B2 (en) Blended polymers of monovinyl aromatic compounds with rubbery polymers of 1, 3-dienes
KR850004985A (ko) 미생물에 의한 l-라이신의 제조방법
KR860001197A (ko) 용선의 예비처리제
KR870001360A (ko) 스피릿트레자를이용한합성피혁의제법
Protyniak The American Imperialist Policy in the Philippines and It’s Anti-Imperialist Reaction

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303