KR840004511A - 세스키테르펜 락톤 화합물의 제조방법 - Google Patents

세스키테르펜 락톤 화합물의 제조방법 Download PDF

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Publication number
KR840004511A
KR840004511A KR1019830002209A KR830002209A KR840004511A KR 840004511 A KR840004511 A KR 840004511A KR 1019830002209 A KR1019830002209 A KR 1019830002209A KR 830002209 A KR830002209 A KR 830002209A KR 840004511 A KR840004511 A KR 840004511A
Authority
KR
South Korea
Prior art keywords
lactone compound
sesquiterpene lactone
preparing
preparing sesquiterpene
solvent
Prior art date
Application number
KR1019830002209A
Other languages
English (en)
Inventor
스테워트 존슨 에드워드 (외 2)
Original Assignee
스테워트 존슨 에드워드 (외 2)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26282867&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR840004511(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 스테워트 존슨 에드워드 (외 2) filed Critical 스테워트 존슨 에드워드 (외 2)
Publication of KR840004511A publication Critical patent/KR840004511A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

세스키테르펜 락톤 화합물의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 타나세튬 파르테니움(Tanacetum Parthenium)을 비극성 용매로 처리하고, 이 용매를 증발시켜 얻은 추출물을 비극성용매를 첫 용출액으로 사용하는 크로마토그래피를 행하여 제약용도로 쓰이는 세스키테르펜락톤(sesquitezpene lactone)함유 추출물을 제조하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019830002209A 1982-05-19 1983-05-19 세스키테르펜 락톤 화합물의 제조방법 KR840004511A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8214572 1982-05-19
GB821457 1982-05-19
GB8227062 1982-09-22
GB82-27062 1982-09-22

Publications (1)

Publication Number Publication Date
KR840004511A true KR840004511A (ko) 1984-10-22

Family

ID=26282867

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830002209A KR840004511A (ko) 1982-05-19 1983-05-19 세스키테르펜 락톤 화합물의 제조방법

Country Status (13)

Country Link
US (1) US4758433A (ko)
EP (1) EP0098041B1 (ko)
KR (1) KR840004511A (ko)
AR (1) AR230008A1 (ko)
AU (1) AU564371B2 (ko)
CA (1) CA1270843A (ko)
DE (1) DE3380306D1 (ko)
DK (1) DK219083A (ko)
FI (1) FI831740L (ko)
GB (1) GB2124486B (ko)
IE (1) IE55766B1 (ko)
NO (1) NO831762L (ko)
NZ (1) NZ204256A (ko)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3635522A1 (de) * 1986-10-18 1988-04-28 Euro Celtique Sa Pharmazeutische zusammensetzung
ATE86114T1 (de) * 1987-12-23 1993-03-15 Psoricur Ltd Medizinische zusammensetzungen gegen psoriasis.
GB9100581D0 (en) * 1991-01-11 1991-02-27 Rhodes Technology Method for the extraction of sesquiterpene lactones
DE4202657C2 (de) * 1992-01-31 1995-10-12 Schaper & Bruemmer Gmbh Pharmazeutisch wirksame Zusammensetzung aus Tanacetum parthenium sowie Verfahren zu deren Extraktion und mit der pharmazeutisch wirksamen Zusammensetzung hergestelltes Arzneimittel
US5576329A (en) * 1992-07-24 1996-11-19 Hennessey; Richard K. Method for treating tendon or joint inflammation with papaverine HCL
US5278172A (en) * 1992-07-24 1994-01-11 Hennessey Richard K Method and composition for treating tendon or joint inflammation using a vasodilator
CN1056142C (zh) * 1993-01-04 2000-09-06 昆明医学院第一附属医院 水朝阳内酯的制备方法
CA2141126A1 (en) * 1995-01-26 1996-07-27 Natalie J. Lazarowych Combinational drug for treating migraine and other illnesses
US6379714B1 (en) 1995-04-14 2002-04-30 Pharmaprint, Inc. Pharmaceutical grade botanical drugs
US5665731A (en) * 1995-06-07 1997-09-09 Hennessey; Richard K. Method and composition for treating with a vasodilator inflammation, bone loss and detachment of teeth as associated with periodontal
AU711019B2 (en) 1996-10-21 1999-10-07 Eurovita A/S Pharmaceutical compositions containing parthenium integrifolium or parts thereof or an extract or component thereof, the use of such plant material for preparing certain medicines, and a method of preparing an extract of parthenium integrifolium
US5905089A (en) * 1997-04-14 1999-05-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Use of sesquiterpene lactones for treatment of severe inflammatory disorders
US5972916A (en) * 1997-07-14 1999-10-26 Bristol-Myers Squibb Company Compositions containing the nonprescription combination of acetaminophen, aspirin and caffeine to alleviate the pain and symptoms of migraine
WO1999033463A1 (en) * 1997-12-23 1999-07-08 Moser, René SESQUITERPENE LACTONES SPECIFICALLY INHIBIT ACTIVATION OF NF-λB BY PREVENTING THE DEGRADATION OF IλB-α AND IλB-$g(b)
US6225339B1 (en) 1998-01-29 2001-05-01 Pfizer Inc. Terpenoid lactone compounds and their production process
US6068999A (en) * 1998-06-25 2000-05-30 Hendrix; Curt Dietary supplement for supporting cerebrovascular tone and treating migraine headaches
US6221899B1 (en) 1999-01-15 2001-04-24 Pfizer Inc. Terpenoid lactone compounds and their production process
IT1312342B1 (it) * 1999-06-03 2002-04-15 Indena Spa Estratto di tanacetum parthenium sostanzialmente privo di gammalattoni-alfa-insaturi.
PT1100516E (pt) * 1999-06-03 2005-07-29 Johnson & Johnson Consumer Fr Extratos de matricaria (tanacetum parthenium) contra doencas inflamatorias
US20030003170A1 (en) * 2000-06-02 2003-01-02 Theresa Callaghan Method for the topical treatment and prevention of inflammatory disorders and related conditions using extracts of feverfew (Tanacetum parthenium)
US6642243B1 (en) 1999-07-22 2003-11-04 Ashkan Imanzahrai Migraine medicine and method for treating same
DE10015617A1 (de) * 2000-03-29 2001-10-04 Peter Laetzsch Migränemittel
IN188857B (ko) * 2000-07-14 2002-11-16 Govind Kane Dr Shantaram
US20030077343A1 (en) * 2001-03-16 2003-04-24 Martin Katharine M. Composition containing feverfew extract and use thereof
DE60220145T2 (de) * 2001-03-16 2008-02-14 Johnson & Johnson Consumer Companies, Inc. Verwendung eines mutterkrautextrakts zur regulierung der hautalterung
US20040086579A1 (en) * 2002-11-05 2004-05-06 Higgins James W. Dietary supplement comprising parthenolide
US7192614B2 (en) 2002-11-05 2007-03-20 Gelstat Corporation Compositions and methods of treatment to alleviate or prevent migrainous headaches and their associated symptoms
US20040219229A1 (en) * 2003-04-30 2004-11-04 Tim Clarot Migraine relief composition and methods of using and forming same
US20040247706A1 (en) * 2003-06-06 2004-12-09 Roberts Stephen C. Transdermal dietary supplement comprising parthenolide
US20040247705A1 (en) * 2003-06-06 2004-12-09 Roberts Stephen C. Transdermal compositions and methods of treatment to alleviate or prevent migrainous headaches and their associated symptoms
US7678904B2 (en) 2003-07-11 2010-03-16 University Of Kentucky Use of parthenolide derivatives as antileukemic and cytotoxic agents
US20050186269A1 (en) * 2004-02-25 2005-08-25 Udell Ronald G. Stabilized feverfew formulations
US20060222722A1 (en) * 2005-03-30 2006-10-05 Roberts Stephen C Sublingual methods of treatment to alleviate or prevent arthritis
US8409637B2 (en) * 2007-06-21 2013-04-02 Puramed Bioscience Inc. Compositions and methods for treating and preventing migrainous headaches and associated symptoms
US10500182B2 (en) * 2018-01-10 2019-12-10 Robert Firger Compositions of ketogenic sources, micronutrients and phytochemicals for prophylaxis and mitigation of migraine headache
CN109761994B (zh) * 2019-02-28 2021-06-29 中国科学院新疆理化技术研究所 降碳类愈创木烷型倍半萜内酯类化合物及其制备方法

Also Published As

Publication number Publication date
EP0098041B1 (en) 1989-08-02
DK219083D0 (da) 1983-05-17
US4758433A (en) 1988-07-19
NO831762L (no) 1983-11-21
CA1270843A (en) 1990-06-26
DE3380306D1 (en) 1989-09-07
IE831164L (en) 1983-11-19
GB8313530D0 (en) 1983-06-22
AR230008A1 (es) 1984-02-29
GB2124486B (en) 1986-07-16
EP0098041A3 (en) 1984-12-12
EP0098041A2 (en) 1984-01-11
NZ204256A (en) 1988-02-29
GB2124486A (en) 1984-02-22
FI831740L (fi) 1983-11-20
FI831740A0 (fi) 1983-05-18
DK219083A (da) 1983-11-20
IE55766B1 (en) 1991-01-16
AU564371B2 (en) 1987-08-13
AU1464683A (en) 1983-11-24

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