ES480605A1 - Procedimiento para la obtencion de derivados o-sustituidos del (mas)-cianidanol-3. - Google Patents

Procedimiento para la obtencion de derivados o-sustituidos del (mas)-cianidanol-3.

Info

Publication number
ES480605A1
ES480605A1 ES480605A ES480605A ES480605A1 ES 480605 A1 ES480605 A1 ES 480605A1 ES 480605 A ES480605 A ES 480605A ES 480605 A ES480605 A ES 480605A ES 480605 A1 ES480605 A1 ES 480605A1
Authority
ES
Spain
Prior art keywords
preparation
radical
cyanidan
compounds
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES480605A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK Consumer Healthcare SARL
Original Assignee
Zyma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zyma SA filed Critical Zyma SA
Publication of ES480605A1 publication Critical patent/ES480605A1/es
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B37/00—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding
    • B32B37/28—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding involving assembly of non-flat intermediate products which are flattened at a later step, e.g. tubes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)

Abstract

Procedimiento para la obtención de derivados 0-sustituidos del (+)-cianidanol-3, que corresponden a la fórmula I: **( formula)** en la que R10 representa un grupo hidroxi protegido que es fácilmente hidrolizable o hidrogenolizable, caracterizado porque la sal tetraalcalina del (+)-cianianol-3 se hace reaccionar con un éster reactivo de un alcohol de formula -HO-R1.
ES480605A 1977-11-25 1979-05-16 Procedimiento para la obtencion de derivados o-sustituidos del (mas)-cianidanol-3. Expired ES480605A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1447977 1977-11-25
CH293778 1978-03-17

Publications (1)

Publication Number Publication Date
ES480605A1 true ES480605A1 (es) 1980-04-01

Family

ID=25691766

Family Applications (2)

Application Number Title Priority Date Filing Date
ES475338A Expired ES475338A1 (es) 1977-11-25 1978-11-23 Procedimiento para la obtencion de derivados o-sustituidos del (+)-cianidanol-3
ES480605A Expired ES480605A1 (es) 1977-11-25 1979-05-16 Procedimiento para la obtencion de derivados o-sustituidos del (mas)-cianidanol-3.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES475338A Expired ES475338A1 (es) 1977-11-25 1978-11-23 Procedimiento para la obtencion de derivados o-sustituidos del (+)-cianidanol-3

Country Status (21)

Country Link
US (2) US4255336A (es)
EP (2) EP0039844A3 (es)
JP (1) JPS5481274A (es)
AT (1) AT364835B (es)
AU (1) AU526985B2 (es)
CA (1) CA1171423A (es)
CS (1) CS228112B2 (es)
DD (2) DD141833A5 (es)
DE (1) DE2862384D1 (es)
DK (1) DK525778A (es)
ES (2) ES475338A1 (es)
FI (1) FI783593A (es)
HK (1) HK15287A (es)
IE (1) IE48250B1 (es)
IL (1) IL56030A (es)
MY (1) MY8700725A (es)
NO (2) NO152651C (es)
NZ (1) NZ189011A (es)
PL (1) PL120640B1 (es)
SG (1) SG82886G (es)
YU (1) YU41030B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4285964A (en) * 1979-08-30 1981-08-25 Continental Pharma Salts of (+)-catechine, their preparation and use, and compositions containing these salts
DE3176349D1 (en) * 1980-04-03 1987-09-17 Zyma Sa Use of o-substituted derivatives of (+)-cyanidanol-3 as compounds with immunomodulative properties
GB2122608B (en) * 1982-06-01 1985-10-02 Zyma Sa (+)-cyanidan-3-ol derivatives
GB2122987B (en) * 1982-06-01 1985-09-25 Zyma Sa (+)-cyanidan-3-ol derivatives and pharmaceutical preparations thereof
DE3715779A1 (de) * 1987-05-12 1988-11-24 Kali Chemie Pharma Gmbh Flavon-3-carbonsaeure-verbindungen sowie verfahren, zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JP3165279B2 (ja) * 1993-03-29 2001-05-14 三井農林株式会社 ３−アシル化カテキンを含有する油溶性抗酸化剤
FR2706478B1 (fr) * 1993-06-14 1995-09-08 Ovi Sa Compositions de dérivés phénoliques, leur préparation et leurs applications comme anti-oxydants.
FR2728563B1 (fr) * 1994-12-21 1997-07-18 Ovi Sa Esters de composes polyhydroxyles aromatiques, leur preparation et leurs applications
US6207842B1 (en) * 1997-10-09 2001-03-27 Mars Incorporated Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives
AU8627798A (en) * 1998-06-18 2000-01-05 Consiglio Nazionale Delle Ricerche Biocatalytic process for the preparation of 3-0-acyl-flavonoids
US6156912A (en) * 1999-04-09 2000-12-05 Mars, Incorporated 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation
US7015338B1 (en) 1999-04-15 2006-03-21 Mars Incorporated Synthetic methods for preparing procyanidin oligomers
US6476241B1 (en) 2000-09-05 2002-11-05 Mars Incorporated Synthesis of 4α-arylepicatechins
US7067679B2 (en) * 2002-10-02 2006-06-27 Mars, Inc. Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest
US7122573B2 (en) * 2002-12-06 2006-10-17 Sri International Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents
KR20060082790A (ko) * 2003-06-20 2006-07-19 코그니스 프랑스 에스.에이.에스. ω-치환된 Ｃ６－Ｃ２２ 지방산을 갖는 플라보노이드의에스테르
TW200505468A (en) * 2003-08-11 2005-02-16 Suntory Ltd Agent for improving hepato-bililary dysfunction
AU2003267173B2 (en) * 2003-09-12 2009-09-10 Mitsui Norin Co., Ltd Antimicrobial compositions and methods of use
EP1763360A4 (en) * 2004-04-02 2009-08-19 Ind Res Ltd L L C FRUIT EXTRACTS FROM PASSION AND USES THEREOF
CN101018793A (zh) * 2004-09-14 2007-08-15 味之素欧姆尼凯姆股份有限公司 作为颜色稳定剂的磷酰化多酚
EP1797055A4 (en) * 2004-09-22 2009-11-11 Indspec Chemical Corp IGNIFUGES IN THE FORM OF PHOSPHATE ESTERS OBTAINED FROM RESORCINOL-KETONE REACTION PRODUCTS
WO2006080328A1 (ja) * 2005-01-26 2006-08-03 Suntory Limited カテキン類のエステル化物、その製造方法、および該エステル化物を含む飲食品あるいは化粧品
US20070004796A1 (en) * 2005-06-29 2007-01-04 Romanczyk Leo Jr Processes for the preparation of protected-(+)-catechin and (-)-epicatechin monomers, for coupling the protected monomers with an activated, protected epicatechin monomer, and for the preparation of epicatechin-(4B,8)-epicatechin or -catechin dimers and their digallates
CN106565658A (zh) * 2016-10-21 2017-04-19 浙江大学 3‑硫酸基儿茶素的制备方法
EP4431169A1 (en) 2023-03-17 2024-09-18 Siegfried AG Method of purifying cannabinoid components from plant extracts

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2861992A (en) * 1955-08-29 1958-11-25 Rech S Et Tech Appliquees Derivatives of quercetin and to prodesses for their preparation
US3314975A (en) * 1963-01-25 1967-04-18 Jurd Leonard Flavylium compounds and methods of using them
FR7760M (es) * 1968-11-22 1970-03-16
US3661890A (en) * 1970-03-10 1972-05-09 Us Agriculture Preparation of quercetin derivatives
CH514574A (fr) * 1970-03-13 1971-10-31 Zyma Sa Procédé de fabrication de sels des acides épicatéchine sulfoniques-2
FR2128207B1 (es) * 1971-03-11 1974-08-02 Zyma Sa
GB1575004A (en) * 1976-03-23 1980-09-17 Iverni Della Beffa Spa Pharmacologically active polyphenolic substances
DE2740346C2 (de) * 1976-09-08 1987-02-05 Inverni Della Beffa S.P.A., Mailand/Milano Pharmazeutische Zubereitung mit narbenbildender, Epithelium-regenerierender, entzündungshemmender, gefäßschützender, hypolipämischer, hypocholesterinämischer und/oder hypoglykämischer Wirkung

Also Published As

Publication number Publication date
IL56030A (en) 1985-08-30
NZ189011A (en) 1981-01-23
DK525778A (da) 1979-05-26
AU4187778A (en) 1979-05-31
IE48250B1 (en) 1984-11-14
HK15287A (en) 1987-02-27
US4617296A (en) 1986-10-14
YU275378A (en) 1982-10-31
PL211196A1 (pl) 1979-11-19
CS228112B2 (en) 1984-05-14
YU41030B (en) 1986-10-31
PL120640B1 (en) 1982-03-31
IL56030A0 (en) 1979-01-31
DD141833A5 (de) 1980-05-21
NO830800L (no) 1979-05-28
DD148055A5 (de) 1981-05-06
ATA835678A (de) 1981-04-15
AT364835B (de) 1981-11-25
AU526985B2 (en) 1983-02-10
CA1171423A (en) 1984-07-24
EP0039844A2 (de) 1981-11-18
NO152651C (no) 1985-10-30
JPS5481274A (en) 1979-06-28
EP0039844A3 (de) 1981-11-25
EP0003274B1 (de) 1984-02-29
NO783968L (no) 1979-05-28
IE782326L (en) 1979-05-25
US4255336A (en) 1981-03-10
EP0003274A1 (de) 1979-08-08
NO152651B (no) 1985-07-22
SG82886G (en) 1987-07-03
FI783593A (fi) 1979-05-26
MY8700725A (en) 1987-12-31
ES475338A1 (es) 1980-03-01
DE2862384D1 (en) 1984-04-05

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