ES2013806A6 - Nuevos derivados de la 19-nor progesterona y su procedimiento de obtencion. - Google Patents

Nuevos derivados de la 19-nor progesterona y su procedimiento de obtencion.

Info

Publication number
ES2013806A6
ES2013806A6 ES8803288A ES8803288A ES2013806A6 ES 2013806 A6 ES2013806 A6 ES 2013806A6 ES 8803288 A ES8803288 A ES 8803288A ES 8803288 A ES8803288 A ES 8803288A ES 2013806 A6 ES2013806 A6 ES 2013806A6
Authority
ES
Spain
Prior art keywords
general formula
field
chemistry
compounds
norprogesterone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES8803288A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Theramex SAM
Original Assignee
Laboratoire Theramex SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex SAM filed Critical Laboratoire Theramex SAM
Publication of ES2013806A6 publication Critical patent/ES2013806A6/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

NUEVOS DERIVADOS DE LA 19-NOR PROGESTERONA Y SU PROCEDIMIENTO DE OBTENCION. LA INVENCION SE REFIERE A UN PROCEDIMIENTO DE PREPARACION DE NUEVOS DERIVADOS DE 19-NOR PROGESTERONA DE FORMULA GENERAL (I), EN LA QUE R REPRESENTA ALQUILO INFERIOR, METOXIMETILO, TETRAHIDROPIRANILO, O UN RESTO ACILO DE ACIDO CARBOXILIXO, CARBONICO, ALIFATICO O AROMATICO, CARACTERIZADO PORQUE UN DERIVADO 3-ALCOXI-1,3,5-TRIENO O 3-ALCOXI-3,5-DIENO DE 17-CETO-18-METIL-GONADIENO II, SE SOMETE A LA ACCION DE UN HALOGENURO DE TRIARILPROPIL FOSFONICO O DEL IDILO CORRESPONDIENTE PARA OBTENER EL CORRESPONDIENTE DERIVADO PROPILIDENICO, QUE SE SOMETE SUCESIVAMENTE A HIDROGENACION POR EL METODO DE BIRCH, ALQUILACION EN MEDIO ACIDO Y FORMILACION DE VILSMEIER-HACK, PARA DAR EL CORRESPONDIENTE DERIVADO 6-FORMILO, QUE TRAS REDUCCION CON HIDRURO MIXTO E HIDROLIZACION RINDE EL DERIVADO 3-OXO-6-METILENICO, QUE DESPUES DE ISOMERIZACION SE BISHIDROLIZA CON TETROXIDO DE OSMIO E HIPEROXIDO DE N-OXIDO AL DERIVADO 17-HIDROXI-20-CETO, QUE TRAS ALQUILACION RINDE EL COMPUESTO DE REFERENCIA.
ES8803288A 1987-10-27 1988-10-27 Nuevos derivados de la 19-nor progesterona y su procedimiento de obtencion. Expired - Fee Related ES2013806A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8714806A FR2622194B1 (fr) 1987-10-27 1987-10-27 Nouveaux derives de la 19-nor progesterone, leur procede d'obtention et les compositions pharmaceutiques en contenant

Publications (1)

Publication Number Publication Date
ES2013806A6 true ES2013806A6 (es) 1990-06-01

Family

ID=9356179

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8803288A Expired - Fee Related ES2013806A6 (es) 1987-10-27 1988-10-27 Nuevos derivados de la 19-nor progesterona y su procedimiento de obtencion.

Country Status (11)

Country Link
EP (1) EP0338065B1 (es)
JP (1) JPH02501931A (es)
KR (1) KR970005317B1 (es)
DE (1) DE3887505D1 (es)
DK (1) DK303589A (es)
ES (1) ES2013806A6 (es)
FI (1) FI91158C (es)
FR (1) FR2622194B1 (es)
OA (1) OA09456A (es)
RU (1) RU2009146C1 (es)
WO (1) WO1989003839A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2675047B1 (fr) * 1991-04-09 1995-05-12 Theramex Nouvelles compositions pharmaceutiques anti-glaucomateuses et leur procede d'obtention.
DE69230069T2 (de) * 1991-06-18 2000-05-25 Laboratoire Theramex S.A., Monaco Steroide enthaltende zusammensetzungen zur anwendung am auge und ihre verwendung zur behandlung des glaukoms
EP0711169B1 (en) * 1993-06-15 2003-12-10 Pherin Corporation Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
KR101878576B1 (ko) * 2016-12-30 2018-07-13 박수종 브러시 교체가 가능한 두피 마사지기

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB924981A (en) * 1960-05-11 1963-05-01 Pfizer & Co C Steroid compounds and compositions thereof
FR2077877B1 (es) * 1970-02-20 1974-02-01 Roussel Uclaf
GB1515284A (en) * 1974-05-21 1978-06-21 Gastaud J Pharmaceutical compositions containing progestogens derived from the 17-alpha-hydroxy-19-nor-progesterone series

Also Published As

Publication number Publication date
FI893121A (fi) 1989-06-27
JPH02501931A (ja) 1990-06-28
WO1989003839A1 (fr) 1989-05-05
KR890701613A (ko) 1989-12-21
KR970005317B1 (ko) 1997-04-15
FI893121A0 (fi) 1989-06-27
FR2622194B1 (fr) 1990-03-23
FI91158C (fi) 1994-05-25
EP0338065B1 (fr) 1994-01-26
DE3887505D1 (de) 1994-03-10
RU2009146C1 (ru) 1994-03-15
DK303589A (da) 1989-08-22
EP0338065A1 (fr) 1989-10-25
FR2622194A1 (fr) 1989-04-28
FI91158B (fi) 1994-02-15
OA09456A (fr) 1992-11-15
DK303589D0 (da) 1989-06-20

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2008-10-27

FD1A Patent lapsed

Effective date: 20001009