ES443011A1 - Un procedimiento de preparacion de una tieno (1,5)-benzodia-zepina. - Google Patents

Un procedimiento de preparacion de una tieno (1,5)-benzodia-zepina.

Info

Publication number
ES443011A1
ES443011A1 ES443011A ES443011A ES443011A1 ES 443011 A1 ES443011 A1 ES 443011A1 ES 443011 A ES443011 A ES 443011A ES 443011 A ES443011 A ES 443011A ES 443011 A1 ES443011 A1 ES 443011A1
Authority
ES
Spain
Prior art keywords
formula
hydrogen
see formula
see
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES443011A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES443011(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of ES443011A1 publication Critical patent/ES443011A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES443011A 1974-11-26 1975-11-26 Un procedimiento de preparacion de una tieno (1,5)-benzodia-zepina. Expired ES443011A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB51240/74A GB1533235A (en) 1974-11-26 1974-11-26 Benzodiazepine derivatives

Publications (1)

Publication Number Publication Date
ES443011A1 true ES443011A1 (es) 1977-07-01

Family

ID=10459213

Family Applications (1)

Application Number Title Priority Date Filing Date
ES443011A Expired ES443011A1 (es) 1974-11-26 1975-11-26 Un procedimiento de preparacion de una tieno (1,5)-benzodia-zepina.

Country Status (30)

Country Link
JP (1) JPS6044314B2 (cs)
AR (1) AR221203A1 (cs)
AT (1) AT351547B (cs)
AU (1) AU506340B2 (cs)
BE (1) BE835932A (cs)
BG (1) BG29573A3 (cs)
CA (1) CA1075687A (cs)
CH (2) CH613455A5 (cs)
CS (1) CS236753B2 (cs)
DD (1) DD123343A5 (cs)
DE (1) DE2552403C2 (cs)
DK (1) DK146887C (cs)
ES (1) ES443011A1 (cs)
FR (1) FR2292479A1 (cs)
GB (1) GB1533235A (cs)
HK (1) HK58681A (cs)
HU (1) HU172493B (cs)
IE (1) IE42564B1 (cs)
IL (1) IL48502A (cs)
KE (1) KE3163A (cs)
MY (1) MY8200149A (cs)
NL (1) NL186088C (cs)
NZ (1) NZ179335A (cs)
PH (2) PH11669A (cs)
PL (1) PL100135B1 (cs)
RO (1) RO69912A (cs)
SE (2) SE421209B (cs)
SU (2) SU629879A3 (cs)
YU (1) YU298375A (cs)
ZA (1) ZA757344B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en) 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
EP0582368B1 (en) * 1992-05-29 2001-01-24 Eli Lilly And Company Limited Thienobenzodiazepine derivatives for treatment of CNS disorders
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
JP3188715B2 (ja) * 1995-11-01 2001-07-16 メルク エンド カンパニー インコーポレーテッド 一酸化窒素シンターゼの阻害物質としてのヘキサヒドロ−5−イミノ−1,4−ヘテロアゼピン誘導体
CN1268949A (zh) 1997-09-02 2000-10-04 吉富制药株式会社 稠合噻吩化合物及其医药用途
RU2185383C1 (ru) * 2001-05-22 2002-07-20 Институт молекулярной генетики РАН ВЫСОКОМЕЧЕННЫЙ ТРИТИЕМ 2-МЕТИЛ-4-(4-МЕТИЛ-1-ПИПЕРАЗИНИЛ)-10Н-ТИЕНО[2,3-b][1,5]БЕНЗОДИАЗЕПИН
PL199016B1 (pl) * 2002-06-20 2008-08-29 Adamed Sp Z Oo Sposób wytwarzania olanzapiny
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
DE10301923B3 (de) 2003-01-17 2004-09-16 Krka Tovarna Zdravil, D.D. Verfahren und Zwischenprodukte zur Herstellung von Olanzapin
WO2005070937A1 (en) * 2004-01-27 2005-08-04 Synthon B.V. A process for making olanzapine in a polymorph form i
AR048272A1 (es) 2004-03-18 2006-04-12 Lek Pharmaceuticals Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales.
DK1778243T3 (da) * 2004-06-30 2013-02-04 Athersys Inc Substituerede azepinderivater som serotoninreceptormodulatorer
EP2292624A1 (en) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Process for the purification of olanzapine

Also Published As

Publication number Publication date
PL100135B1 (pl) 1978-09-30
PH24534A (en) 1990-08-03
ATA898275A (de) 1979-01-15
KE3163A (en) 1981-10-16
DK146887B (da) 1984-01-30
IL48502A0 (en) 1976-01-30
PH11669A (en) 1978-05-19
SE421209B (sv) 1981-12-07
DE2552403C2 (de) 1986-06-19
IE42564B1 (en) 1980-09-10
CH613455A5 (en) 1979-09-28
AT351547B (de) 1979-07-25
JPS6044314B2 (ja) 1985-10-02
SE429045B (sv) 1983-08-08
NZ179335A (en) 1978-11-13
BE835932A (fr) 1976-05-25
DK146887C (da) 1984-07-09
SU629879A3 (ru) 1978-10-25
DK524175A (da) 1976-05-27
MY8200149A (en) 1982-12-31
YU298375A (en) 1982-10-31
JPS5176296A (en) 1976-07-01
AU8685875A (en) 1977-05-26
DD123343A5 (cs) 1976-12-12
HK58681A (en) 1981-12-04
AU506340B2 (en) 1979-12-20
IL48502A (en) 1980-01-31
DE2552403A1 (de) 1976-08-12
SE7812194L (sv) 1978-11-27
NL186088C (nl) 1990-09-17
CS236753B2 (en) 1985-05-15
HU172493B (hu) 1978-09-28
ZA757344B (en) 1976-11-24
CA1075687A (en) 1980-04-15
CH613454A5 (en) 1979-09-28
NL186088B (nl) 1990-04-17
FR2292479B1 (cs) 1978-07-28
AR221203A1 (es) 1981-01-15
NL7513833A (nl) 1976-05-31
GB1533235A (en) 1978-11-22
IE42564L (en) 1976-05-26
RO69912A (ro) 1980-08-15
FR2292479A1 (fr) 1976-06-25
BG29573A3 (en) 1980-12-12
SU626702A3 (ru) 1978-09-30
SE7513185L (sv) 1976-05-27

Similar Documents

Publication Publication Date Title
ES443011A1 (es) Un procedimiento de preparacion de una tieno (1,5)-benzodia-zepina.
EP0048763A4 (en) ACYLAMINO ACIDS CONTAINING SULFUR.
ES432131A1 (es) Un procedimiento para la obtencion de esteres y carbamatos de amino alcoholes.
TW197421B (cs)
ES448408A1 (es) Un procedimiento de preparacion de derivados de acidos 5-ar-vil-1-alquil (inferior) pirrol-2-aceticos.
ES8102136A1 (es) Procedimiento para la obtencion de derivados de vinil-3 ce- falosporina
TW328077B (en) Process for the preparation of thioamide
ES417638A1 (es) Procedimiento para preparar oxazoles 2,4,5-trisustituidos.
PT79118A (de) Cephalosporinderivate und verfahren zur ihrer herstellung
ES527739A0 (es) Un procedimiento para preparar derivados de pirimidina
ATE38665T1 (de) Verfahren zur herstellung von 5-perfluoralkyl-5,6-dihydrouracyl-derivaten und verwendbare zwischenprodukte.
ES423058A1 (es) Procedimiento de preparacion de nuevos deivados de la i- soindolina.
ES453121A1 (es) Un metodo de preparacion de nuevos derivados de piridil u- reas.
DE3560027D1 (en) Process for the preparation of o,o'-dithiobenzamides
ATE94878T1 (de) Imidazobenzodiazepine und ihre saeureadditionssalze, verfahren und zwischenprodukte zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende zubereitungen.
ES475120A1 (es) Un procedimiento para la preparacion de imidazo (1,5-b)piri-dazinas.
MY101938A (en) Benzothiazoline fungicides
ES451209A1 (es) Procedimiento de fabricacion de sulfoximidas sustituidas y sus sales medicamentosas.
DE3062043D1 (en) Peptide amides and process for their preparation
ATE29496T1 (de) Tetrahydro-beta-carbolin-derivate und verfahren fuer ihre herstellung.
ES480562A1 (es) Un procedimiento para la preparacion de un nuevo vincaderi- vado dimero.
ATE27955T1 (de) Verfahren und zwischenprodukte zur herstellung von 2-substituierten 4-acetyl-imidazolen.
IE43092L (en) 4-amino-pyridines.
DE3788369D1 (de) Verfahren zur Herstellung von Cephalosporinderivaten.
ES455962A1 (es) Un procedimiento para la preparacion de compuestos imidazo (1,5-a) (1,4) diacepinicos.