DK146887C - Analogifremgangsmaade til fremstilling af thieno(1,5)benzodiazepinderivater - Google Patents

Analogifremgangsmaade til fremstilling af thieno(1,5)benzodiazepinderivater

Info

Publication number
DK146887C
DK146887C DK524175A DK524175A DK146887C DK 146887 C DK146887 C DK 146887C DK 524175 A DK524175 A DK 524175A DK 524175 A DK524175 A DK 524175A DK 146887 C DK146887 C DK 146887C
Authority
DK
Denmark
Prior art keywords
thieno
preparation
benzodiazepine derivatives
analogy procedure
analogy
Prior art date
Application number
DK524175A
Other languages
English (en)
Other versions
DK524175A (da
DK146887B (da
Inventor
Jiban Kumar Chakrabarti
David Edward Tupper
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK146887(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of DK524175A publication Critical patent/DK524175A/da
Priority to DK375479A priority Critical patent/DK147020C/da
Publication of DK146887B publication Critical patent/DK146887B/da
Application granted granted Critical
Publication of DK146887C publication Critical patent/DK146887C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK524175A 1974-11-26 1975-11-20 Analogifremgangsmaade til fremstilling af thieno(1,5)benzodiazepinderivater DK146887C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK375479A DK147020C (da) 1974-11-26 1979-09-07 Thieno(1,5)benzodiazepinforbindelser til anvendelse som mellemprodukter

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB51240/74A GB1533235A (en) 1974-11-26 1974-11-26 Benzodiazepine derivatives
GB5124074 1974-11-26

Publications (3)

Publication Number Publication Date
DK524175A DK524175A (da) 1976-05-27
DK146887B DK146887B (da) 1984-01-30
DK146887C true DK146887C (da) 1984-07-09

Family

ID=10459213

Family Applications (1)

Application Number Title Priority Date Filing Date
DK524175A DK146887C (da) 1974-11-26 1975-11-20 Analogifremgangsmaade til fremstilling af thieno(1,5)benzodiazepinderivater

Country Status (30)

Country Link
JP (1) JPS6044314B2 (da)
AR (1) AR221203A1 (da)
AT (1) AT351547B (da)
AU (1) AU506340B2 (da)
BE (1) BE835932A (da)
BG (1) BG29573A3 (da)
CA (1) CA1075687A (da)
CH (2) CH613454A5 (da)
CS (1) CS236753B2 (da)
DD (1) DD123343A5 (da)
DE (1) DE2552403C2 (da)
DK (1) DK146887C (da)
ES (1) ES443011A1 (da)
FR (1) FR2292479A1 (da)
GB (1) GB1533235A (da)
HK (1) HK58681A (da)
HU (1) HU172493B (da)
IE (1) IE42564B1 (da)
IL (1) IL48502A (da)
KE (1) KE3163A (da)
MY (1) MY8200149A (da)
NL (1) NL186088C (da)
NZ (1) NZ179335A (da)
PH (2) PH11669A (da)
PL (1) PL100135B1 (da)
RO (1) RO69912A (da)
SE (2) SE421209B (da)
SU (2) SU629879A3 (da)
YU (1) YU298375A (da)
ZA (1) ZA757344B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
CA2097016A1 (en) * 1992-05-29 1993-11-30 John Fairhurst Pharmaceutical compounds
WO1997016430A1 (en) * 1995-11-01 1997-05-09 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
RU2197491C2 (ru) 1997-09-02 2003-01-27 Мицубиси Фарма Корпорейшн Конденсированное производное тиофена, производное бензотиофена, производное тиенобензоксазепинона, фармацевтическое средство и фармацевтическая композиция
PL199016B1 (pl) * 2002-06-20 2008-08-29 Adamed Sp Z Oo Sposób wytwarzania olanzapiny
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
DE10301923B3 (de) * 2003-01-17 2004-09-16 Krka Tovarna Zdravil, D.D. Verfahren und Zwischenprodukte zur Herstellung von Olanzapin
EP1711503A1 (en) * 2004-01-27 2006-10-18 Synthon B.V. Synthesis of olanzapine and intermediates thereof
AR048272A1 (es) 2004-03-18 2006-04-12 Lek Pharmaceuticals Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales.
EP1778243B1 (en) * 2004-06-30 2012-10-31 Athersys, Inc. Substituted azepine derivatives as serotonin receptor modulators
EP2292624A1 (en) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Process for the purification of olanzapine

Also Published As

Publication number Publication date
NL7513833A (nl) 1976-05-31
SE421209B (sv) 1981-12-07
FR2292479A1 (fr) 1976-06-25
DK524175A (da) 1976-05-27
HU172493B (hu) 1978-09-28
MY8200149A (en) 1982-12-31
NL186088B (nl) 1990-04-17
NL186088C (nl) 1990-09-17
IL48502A (en) 1980-01-31
FR2292479B1 (da) 1978-07-28
CH613454A5 (en) 1979-09-28
BG29573A3 (en) 1980-12-12
CS236753B2 (en) 1985-05-15
IE42564B1 (en) 1980-09-10
BE835932A (fr) 1976-05-25
RO69912A (ro) 1980-08-15
DK146887B (da) 1984-01-30
HK58681A (en) 1981-12-04
GB1533235A (en) 1978-11-22
SE7812194L (sv) 1978-11-27
NZ179335A (en) 1978-11-13
JPS5176296A (en) 1976-07-01
JPS6044314B2 (ja) 1985-10-02
AT351547B (de) 1979-07-25
AU8685875A (en) 1977-05-26
SU626702A3 (ru) 1978-09-30
ZA757344B (en) 1976-11-24
DD123343A5 (da) 1976-12-12
IL48502A0 (en) 1976-01-30
PL100135B1 (pl) 1978-09-30
KE3163A (en) 1981-10-16
IE42564L (en) 1976-05-26
CH613455A5 (en) 1979-09-28
PH11669A (en) 1978-05-19
AR221203A1 (es) 1981-01-15
AU506340B2 (en) 1979-12-20
DE2552403C2 (de) 1986-06-19
PH24534A (en) 1990-08-03
YU298375A (en) 1982-10-31
CA1075687A (en) 1980-04-15
ATA898275A (de) 1979-01-15
SE7513185L (sv) 1976-05-27
SU629879A3 (ru) 1978-10-25
SE429045B (sv) 1983-08-08
DE2552403A1 (de) 1976-08-12
ES443011A1 (es) 1977-07-01

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