RO69912A - Procedeu pentru prepararea unor tieno (1,5) benzodiazepine - Google Patents

Procedeu pentru prepararea unor tieno (1,5) benzodiazepine

Info

Publication number
RO69912A
RO69912A RO7584018A RO8401875A RO69912A RO 69912 A RO69912 A RO 69912A RO 7584018 A RO7584018 A RO 7584018A RO 8401875 A RO8401875 A RO 8401875A RO 69912 A RO69912 A RO 69912A
Authority
RO
Romania
Prior art keywords
tieno
benzodiazepines
preparation
Prior art date
Application number
RO7584018A
Other languages
English (en)
French (fr)
Romanian (ro)
Inventor
Jiban K Chakrabarti
David E Tupper
Original Assignee
Lilly Industries Ltd,Gb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RO69912(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Industries Ltd,Gb filed Critical Lilly Industries Ltd,Gb
Publication of RO69912A publication Critical patent/RO69912A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RO7584018A 1974-11-26 1975-11-25 Procedeu pentru prepararea unor tieno (1,5) benzodiazepine RO69912A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB51240/74A GB1533235A (en) 1974-11-26 1974-11-26 Benzodiazepine derivatives

Publications (1)

Publication Number Publication Date
RO69912A true RO69912A (ro) 1980-08-15

Family

ID=10459213

Family Applications (1)

Application Number Title Priority Date Filing Date
RO7584018A RO69912A (ro) 1974-11-26 1975-11-25 Procedeu pentru prepararea unor tieno (1,5) benzodiazepine

Country Status (30)

Country Link
JP (1) JPS6044314B2 (da)
AR (1) AR221203A1 (da)
AT (1) AT351547B (da)
AU (1) AU506340B2 (da)
BE (1) BE835932A (da)
BG (1) BG29573A3 (da)
CA (1) CA1075687A (da)
CH (2) CH613454A5 (da)
CS (1) CS236753B2 (da)
DD (1) DD123343A5 (da)
DE (1) DE2552403C2 (da)
DK (1) DK146887C (da)
ES (1) ES443011A1 (da)
FR (1) FR2292479A1 (da)
GB (1) GB1533235A (da)
HK (1) HK58681A (da)
HU (1) HU172493B (da)
IE (1) IE42564B1 (da)
IL (1) IL48502A (da)
KE (1) KE3163A (da)
MY (1) MY8200149A (da)
NL (1) NL186088C (da)
NZ (1) NZ179335A (da)
PH (2) PH11669A (da)
PL (1) PL100135B1 (da)
RO (1) RO69912A (da)
SE (2) SE421209B (da)
SU (2) SU629879A3 (da)
YU (1) YU298375A (da)
ZA (1) ZA757344B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
EP0582368B1 (en) * 1992-05-29 2001-01-24 Eli Lilly And Company Limited Thienobenzodiazepine derivatives for treatment of CNS disorders
EP0861238A4 (en) * 1995-11-01 2000-03-01 Merck & Co Inc DERIVATIVES OF HEXAHYDRO-5-IMINO-1,4-HETEROAZEPINE INHIBITORS OF NITRIC OXIDE SYNTHASES
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
DE69816102D1 (de) 1997-09-02 2003-08-07 Mitsubishi Pharma Corp Kondensierte thiophenderivate und ihre medizinische anwendung
PL199016B1 (pl) * 2002-06-20 2008-08-29 Adamed Sp Z Oo Sposób wytwarzania olanzapiny
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
DE10301923B3 (de) * 2003-01-17 2004-09-16 Krka Tovarna Zdravil, D.D. Verfahren und Zwischenprodukte zur Herstellung von Olanzapin
EP1720885A1 (en) * 2004-01-27 2006-11-15 Synthon B.V. A process for making olanzapine in a polymorph form i
AR048272A1 (es) 2004-03-18 2006-04-12 Lek Pharmaceuticals Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales.
DK1778243T3 (da) * 2004-06-30 2013-02-04 Athersys Inc Substituerede azepinderivater som serotoninreceptormodulatorer
EP2292624A1 (en) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Process for the purification of olanzapine

Also Published As

Publication number Publication date
CA1075687A (en) 1980-04-15
IL48502A0 (en) 1976-01-30
AT351547B (de) 1979-07-25
NL7513833A (nl) 1976-05-31
HU172493B (hu) 1978-09-28
PL100135B1 (pl) 1978-09-30
MY8200149A (en) 1982-12-31
NL186088C (nl) 1990-09-17
AU8685875A (en) 1977-05-26
AU506340B2 (en) 1979-12-20
AR221203A1 (es) 1981-01-15
SU629879A3 (ru) 1978-10-25
PH11669A (en) 1978-05-19
NZ179335A (en) 1978-11-13
NL186088B (nl) 1990-04-17
IE42564L (en) 1976-05-26
PH24534A (en) 1990-08-03
JPS5176296A (en) 1976-07-01
FR2292479A1 (fr) 1976-06-25
SE421209B (sv) 1981-12-07
BE835932A (fr) 1976-05-25
DK146887B (da) 1984-01-30
HK58681A (en) 1981-12-04
CH613454A5 (en) 1979-09-28
DD123343A5 (da) 1976-12-12
DE2552403A1 (de) 1976-08-12
SE7513185L (sv) 1976-05-27
ZA757344B (en) 1976-11-24
SU626702A3 (ru) 1978-09-30
GB1533235A (en) 1978-11-22
CS236753B2 (en) 1985-05-15
CH613455A5 (en) 1979-09-28
DK524175A (da) 1976-05-27
FR2292479B1 (da) 1978-07-28
DE2552403C2 (de) 1986-06-19
JPS6044314B2 (ja) 1985-10-02
ATA898275A (de) 1979-01-15
IL48502A (en) 1980-01-31
SE429045B (sv) 1983-08-08
IE42564B1 (en) 1980-09-10
DK146887C (da) 1984-07-09
ES443011A1 (es) 1977-07-01
SE7812194L (sv) 1978-11-27
YU298375A (en) 1982-10-31
KE3163A (en) 1981-10-16
BG29573A3 (en) 1980-12-12

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