RO69912A - Procede pour la preparation des tieno(1,5) benzodiazepines - Google Patents

Procede pour la preparation des tieno(1,5) benzodiazepines

Info

Publication number
RO69912A
RO69912A RO7584018A RO8401875A RO69912A RO 69912 A RO69912 A RO 69912A RO 7584018 A RO7584018 A RO 7584018A RO 8401875 A RO8401875 A RO 8401875A RO 69912 A RO69912 A RO 69912A
Authority
RO
Romania
Prior art keywords
tieno
benzodiazepines
preparation
Prior art date
Application number
RO7584018A
Other languages
English (en)
Romanian (ro)
Inventor
Jiban K Chakrabarti
David E Tupper
Original Assignee
Lilly Industries Ltd,Gb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RO69912(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Industries Ltd,Gb filed Critical Lilly Industries Ltd,Gb
Publication of RO69912A publication Critical patent/RO69912A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RO7584018A 1974-11-26 1975-11-25 Procede pour la preparation des tieno(1,5) benzodiazepines RO69912A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB51240/74A GB1533235A (en) 1974-11-26 1974-11-26 Benzodiazepine derivatives

Publications (1)

Publication Number Publication Date
RO69912A true RO69912A (fr) 1980-08-15

Family

ID=10459213

Family Applications (1)

Application Number Title Priority Date Filing Date
RO7584018A RO69912A (fr) 1974-11-26 1975-11-25 Procede pour la preparation des tieno(1,5) benzodiazepines

Country Status (30)

Country Link
JP (1) JPS6044314B2 (fr)
AR (1) AR221203A1 (fr)
AT (1) AT351547B (fr)
AU (1) AU506340B2 (fr)
BE (1) BE835932A (fr)
BG (1) BG29573A3 (fr)
CA (1) CA1075687A (fr)
CH (2) CH613455A5 (fr)
CS (1) CS236753B2 (fr)
DD (1) DD123343A5 (fr)
DE (1) DE2552403C2 (fr)
DK (1) DK146887C (fr)
ES (1) ES443011A1 (fr)
FR (1) FR2292479A1 (fr)
GB (1) GB1533235A (fr)
HK (1) HK58681A (fr)
HU (1) HU172493B (fr)
IE (1) IE42564B1 (fr)
IL (1) IL48502A (fr)
KE (1) KE3163A (fr)
MY (1) MY8200149A (fr)
NL (1) NL186088C (fr)
NZ (1) NZ179335A (fr)
PH (2) PH11669A (fr)
PL (1) PL100135B1 (fr)
RO (1) RO69912A (fr)
SE (2) SE421209B (fr)
SU (2) SU629879A3 (fr)
YU (1) YU298375A (fr)
ZA (1) ZA757344B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
EP0582368B1 (fr) * 1992-05-29 2001-01-24 Eli Lilly And Company Limited Dérivés de thienobenzodiazépine pour le traitement des troubles du système nerveux central
EP0861238A4 (fr) * 1995-11-01 2000-03-01 Merck & Co Inc Derives de l'hexahydro-5-imino-1,4-heteroazepine inhibiteurs des synthases de l'oxyde nitrique
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
NZ503484A (en) * 1997-09-02 2001-10-26 Welfide Corp Optionally benzo fused thieno[2,3-b]benzoxazepine, thieno[2,3-b]benzodiazepine or thieno[2,3-b]benzothiaxazepine derivatives
RU2185383C1 (ru) * 2001-05-22 2002-07-20 Институт молекулярной генетики РАН ВЫСОКОМЕЧЕННЫЙ ТРИТИЕМ 2-МЕТИЛ-4-(4-МЕТИЛ-1-ПИПЕРАЗИНИЛ)-10Н-ТИЕНО[2,3-b][1,5]БЕНЗОДИАЗЕПИН
PL199016B1 (pl) * 2002-06-20 2008-08-29 Adamed Sp Z Oo Sposób wytwarzania olanzapiny
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
DE10301923B3 (de) * 2003-01-17 2004-09-16 Krka Tovarna Zdravil, D.D. Verfahren und Zwischenprodukte zur Herstellung von Olanzapin
EP1711503A1 (fr) * 2004-01-27 2006-10-18 Synthon B.V. Synthese de l'olanzapine, et intermediaires de celle-ci
AR048272A1 (es) 2004-03-18 2006-04-12 Lek Pharmaceuticals Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales.
JP5025469B2 (ja) * 2004-06-30 2012-09-12 アサーシス， インク． セロトニン受容体モジュレーターとしての置換アゼピン誘導体
EP2292624A1 (fr) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Processus de purification d'olanzapine

Also Published As

Publication number Publication date
PH24534A (en) 1990-08-03
DE2552403C2 (de) 1986-06-19
FR2292479A1 (fr) 1976-06-25
FR2292479B1 (fr) 1978-07-28
SU629879A3 (ru) 1978-10-25
NL186088B (nl) 1990-04-17
SE421209B (sv) 1981-12-07
PL100135B1 (pl) 1978-09-30
CH613454A5 (en) 1979-09-28
YU298375A (en) 1982-10-31
IE42564B1 (en) 1980-09-10
HK58681A (en) 1981-12-04
DK146887B (da) 1984-01-30
DK524175A (da) 1976-05-27
NZ179335A (en) 1978-11-13
SE7812194L (sv) 1978-11-27
KE3163A (en) 1981-10-16
DD123343A5 (fr) 1976-12-12
PH11669A (en) 1978-05-19
CS236753B2 (en) 1985-05-15
IE42564L (en) 1976-05-26
IL48502A (en) 1980-01-31
AT351547B (de) 1979-07-25
NL7513833A (nl) 1976-05-31
MY8200149A (en) 1982-12-31
HU172493B (hu) 1978-09-28
SU626702A3 (ru) 1978-09-30
NL186088C (nl) 1990-09-17
IL48502A0 (en) 1976-01-30
DK146887C (da) 1984-07-09
BE835932A (fr) 1976-05-25
JPS5176296A (en) 1976-07-01
JPS6044314B2 (ja) 1985-10-02
AR221203A1 (es) 1981-01-15
ES443011A1 (es) 1977-07-01
BG29573A3 (en) 1980-12-12
CA1075687A (fr) 1980-04-15
SE7513185L (sv) 1976-05-27
CH613455A5 (en) 1979-09-28
SE429045B (sv) 1983-08-08
ATA898275A (de) 1979-01-15
ZA757344B (en) 1976-11-24
AU8685875A (en) 1977-05-26
DE2552403A1 (de) 1976-08-12
GB1533235A (en) 1978-11-22
AU506340B2 (en) 1979-12-20

Similar Documents

Publication Publication Date Title
RO70051A (fr) Procede pour la preparation des 2-tetra-hydrofurfurile-6,7-benzomorphanes
RO68142A (fr) Procede pour la preparation des 4-phenylpyperidines
RO65454A (fr) Procede pour la preparation des calcones substituees
RO69608A (fr) Procede pour la preparation des 1,2-benzisothiazole-3-ones
RO69912A (fr) Procede pour la preparation des tieno(1,5) benzodiazepines
BE838823A (fr) Procede pour la preparation de 1,2,5-dihydroxycholecalciferol
RO68145A (fr) Procede pour la preparation des 3,4-dihydro-2h-1,2-benzothiazincarboxamides
RO67194A (fr) Procede pour la preparation du 2,2,6,6-tetramethyle-4-piperydone
FR2300059A1 (fr) Procede pour la preparation de 2,5-dichloro-p-xylene
RO64606A (fr) Procede pour la preparation des 6-methylergolines-8,8-disubstituees
RO63021A (fr) Procede pour la preparation des 3-fluorcephalosporines
RO67193A (fr) Procede pour la preparation du 2,2,6,6-tetramethyle-4-piperydone
RO64281A (fr) Procede pour la preparation des 6-methyle-8-methylergolines substituees
BE826343A (fr) Procede de preparation de s-triazolo(3,4- bbenzothiazoles
RO76667A (fr) Procede pour la preparation des 2,4-dialkyamino-6-chlore-5-triazines
FR2303798A1 (fr) Procede pour la preparation de (3r, 3'r)-zeaxanthene
RO68749A (fr) Procede pour la preparation des 2-amidoimidazoles
RO70232A (fr) Procede pour la preparation des 4-pyrazolile-4h-1,2,4-triazolile
RO72516A (fr) Procede pour la preparation des quinoxalin-1,4-dioxydes
BE809494A (fr) Procede pour la preparation de 1,4-dioxanne
RO68650A (fr) Procede pour la preparation des imidazole-(1,2-a)-procede pour la preparation des imidazole-(1,2-a)ss-triazines -triazines
BE835855A (fr) Procede de preparation de nouvelles 7,7 -diphenyl - hexahydro - 1,4 - oxazepines
FR2286198A1 (fr) Procede pour la preparation d'agglomeres
FR2283150A1 (fr) Procede pour la preparation d'hydroxy-11b alkyl-18 oestranes
RO70236A (fr) Procede pour la preparation des 1,2,4/oxadiazolioine-3-ones