FR2292479A1 - Derives de benzodiazepine - Google Patents

Derives de benzodiazepine

Info

Publication number
FR2292479A1
FR2292479A1 FR7535900A FR7535900A FR2292479A1 FR 2292479 A1 FR2292479 A1 FR 2292479A1 FR 7535900 A FR7535900 A FR 7535900A FR 7535900 A FR7535900 A FR 7535900A FR 2292479 A1 FR2292479 A1 FR 2292479A1
Authority
FR
France
Prior art keywords
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7535900A
Other languages
English (en)
Other versions
FR2292479B1 (fr
Inventor
Jiban Kumar Chakrabarti
David Edward Tupper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2292479(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of FR2292479A1 publication Critical patent/FR2292479A1/fr
Application granted granted Critical
Publication of FR2292479B1 publication Critical patent/FR2292479B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR7535900A 1974-11-26 1975-11-25 Derives de benzodiazepine Granted FR2292479A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB51240/74A GB1533235A (en) 1974-11-26 1974-11-26 Benzodiazepine derivatives

Publications (2)

Publication Number Publication Date
FR2292479A1 true FR2292479A1 (fr) 1976-06-25
FR2292479B1 FR2292479B1 (fr) 1978-07-28

Family

ID=10459213

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7535900A Granted FR2292479A1 (fr) 1974-11-26 1975-11-25 Derives de benzodiazepine

Country Status (30)

Country Link
JP (1) JPS6044314B2 (fr)
AR (1) AR221203A1 (fr)
AT (1) AT351547B (fr)
AU (1) AU506340B2 (fr)
BE (1) BE835932A (fr)
BG (1) BG29573A3 (fr)
CA (1) CA1075687A (fr)
CH (2) CH613455A5 (fr)
CS (1) CS236753B2 (fr)
DD (1) DD123343A5 (fr)
DE (1) DE2552403C2 (fr)
DK (1) DK146887C (fr)
ES (1) ES443011A1 (fr)
FR (1) FR2292479A1 (fr)
GB (1) GB1533235A (fr)
HK (1) HK58681A (fr)
HU (1) HU172493B (fr)
IE (1) IE42564B1 (fr)
IL (1) IL48502A (fr)
KE (1) KE3163A (fr)
MY (1) MY8200149A (fr)
NL (1) NL186088C (fr)
NZ (1) NZ179335A (fr)
PH (2) PH11669A (fr)
PL (1) PL100135B1 (fr)
RO (1) RO69912A (fr)
SE (2) SE421209B (fr)
SU (2) SU629879A3 (fr)
YU (1) YU298375A (fr)
ZA (1) ZA757344B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0861238A1 (fr) * 1995-11-01 1998-09-02 Merck & Co., Inc. Derives de l'hexahydro-5-imino-1,4-heteroazepine inhibiteurs des synthases de l'oxyde nitrique
US6372733B1 (en) 1995-11-01 2002-04-16 Merck & Co., Inc. Hexahydro-5-imino-1,4-1,4-thiazepine derivatives as inhibitors of nitric oxide synthases

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en) 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
NZ247703A (en) * 1992-05-29 1995-07-26 Lilly Industries Ltd Thienobenzdiazepine derivatives and medicaments thereof
AU739385B2 (en) * 1997-09-02 2001-10-11 Mitsubishi Pharma Corporation Condensed thiophene compounds and pharmaceutical use thereof
PL199016B1 (pl) * 2002-06-20 2008-08-29 Adamed Sp Z Oo Sposób wytwarzania olanzapiny
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
DE10301923B3 (de) * 2003-01-17 2004-09-16 Krka Tovarna Zdravil, D.D. Verfahren und Zwischenprodukte zur Herstellung von Olanzapin
WO2005070937A1 (fr) * 2004-01-27 2005-08-04 Synthon B.V. Procede de fabrication d'olanzapine sous forme polymorphe i
AR048272A1 (es) 2004-03-18 2006-04-12 Lek Pharmaceuticals Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales.
NZ550891A (en) * 2004-06-30 2009-10-30 Athersys Inc Substituted azepine derivatives as serotonin receptor modulators
EP2292624A1 (fr) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Processus de purification d'olanzapine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0861238A1 (fr) * 1995-11-01 1998-09-02 Merck & Co., Inc. Derives de l'hexahydro-5-imino-1,4-heteroazepine inhibiteurs des synthases de l'oxyde nitrique
EP0861238A4 (fr) * 1995-11-01 2000-03-01 Merck & Co Inc Derives de l'hexahydro-5-imino-1,4-heteroazepine inhibiteurs des synthases de l'oxyde nitrique
US6372733B1 (en) 1995-11-01 2002-04-16 Merck & Co., Inc. Hexahydro-5-imino-1,4-1,4-thiazepine derivatives as inhibitors of nitric oxide synthases

Also Published As

Publication number Publication date
CS236753B2 (en) 1985-05-15
CA1075687A (fr) 1980-04-15
JPS5176296A (en) 1976-07-01
RO69912A (fr) 1980-08-15
IL48502A (en) 1980-01-31
BE835932A (fr) 1976-05-25
FR2292479B1 (fr) 1978-07-28
SU629879A3 (ru) 1978-10-25
ES443011A1 (es) 1977-07-01
SE7812194L (sv) 1978-11-27
PH11669A (en) 1978-05-19
NZ179335A (en) 1978-11-13
IE42564B1 (en) 1980-09-10
DK524175A (da) 1976-05-27
PL100135B1 (pl) 1978-09-30
SE421209B (sv) 1981-12-07
MY8200149A (en) 1982-12-31
ATA898275A (de) 1979-01-15
DE2552403A1 (de) 1976-08-12
CH613454A5 (en) 1979-09-28
DE2552403C2 (de) 1986-06-19
AU8685875A (en) 1977-05-26
SE7513185L (sv) 1976-05-27
ZA757344B (en) 1976-11-24
CH613455A5 (en) 1979-09-28
AT351547B (de) 1979-07-25
YU298375A (en) 1982-10-31
JPS6044314B2 (ja) 1985-10-02
AR221203A1 (es) 1981-01-15
HU172493B (hu) 1978-09-28
NL7513833A (nl) 1976-05-31
SU626702A3 (ru) 1978-09-30
NL186088C (nl) 1990-09-17
IE42564L (en) 1976-05-26
DD123343A5 (fr) 1976-12-12
IL48502A0 (en) 1976-01-30
SE429045B (sv) 1983-08-08
NL186088B (nl) 1990-04-17
HK58681A (en) 1981-12-04
PH24534A (en) 1990-08-03
AU506340B2 (en) 1979-12-20
DK146887B (da) 1984-01-30
KE3163A (en) 1981-10-16
BG29573A3 (en) 1980-12-12
GB1533235A (en) 1978-11-22
DK146887C (da) 1984-07-09

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