IE42564L - Thieno-benzodiazepine derivatives - Google Patents

Thieno-benzodiazepine derivatives

Info

Publication number
IE42564L
IE42564L IE752565A IE256575A IE42564L IE 42564 L IE42564 L IE 42564L IE 752565 A IE752565 A IE 752565A IE 256575 A IE256575 A IE 256575A IE 42564 L IE42564 L IE 42564L
Authority
IE
Ireland
Prior art keywords
thieno
benzodiazepine derivatives
piperazino
benzodiazepines
amino
Prior art date
Application number
IE752565A
Other versions
IE42564B1 (en
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE42564(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Priority to IE1607/79A priority Critical patent/IE42565B1/en
Publication of IE42564L publication Critical patent/IE42564L/en
Publication of IE42564B1 publication Critical patent/IE42564B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Thieno1,5!benzodiazepines having useful CNS activity containing the novel tricyclic ring system : the 10-position being substituted by an amino, preferably a piperazino, group. Thieno¢1,5!benzodiazepines having useful CNS activity containing the novel tricyclic ring system : the 10-position being substituted by an amino, preferably a piperazino, group. [CA1075687A]
IE2565/75A 1974-11-26 1975-11-25 Benzodiazepine derivatives IE42564B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IE1607/79A IE42565B1 (en) 1974-11-26 1975-11-25 Thieno (1,5) benzodiazepine intermediates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB51240/74A GB1533235A (en) 1974-11-26 1974-11-26 Benzodiazepine derivatives

Publications (2)

Publication Number Publication Date
IE42564L true IE42564L (en) 1976-05-26
IE42564B1 IE42564B1 (en) 1980-09-10

Family

ID=10459213

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2565/75A IE42564B1 (en) 1974-11-26 1975-11-25 Benzodiazepine derivatives

Country Status (30)

Country Link
JP (1) JPS6044314B2 (en)
AR (1) AR221203A1 (en)
AT (1) AT351547B (en)
AU (1) AU506340B2 (en)
BE (1) BE835932A (en)
BG (1) BG29573A3 (en)
CA (1) CA1075687A (en)
CH (2) CH613454A5 (en)
CS (1) CS236753B2 (en)
DD (1) DD123343A5 (en)
DE (1) DE2552403C2 (en)
DK (1) DK146887C (en)
ES (1) ES443011A1 (en)
FR (1) FR2292479A1 (en)
GB (1) GB1533235A (en)
HK (1) HK58681A (en)
HU (1) HU172493B (en)
IE (1) IE42564B1 (en)
IL (1) IL48502A (en)
KE (1) KE3163A (en)
MY (1) MY8200149A (en)
NL (1) NL186088C (en)
NZ (1) NZ179335A (en)
PH (2) PH11669A (en)
PL (1) PL100135B1 (en)
RO (1) RO69912A (en)
SE (2) SE421209B (en)
SU (2) SU629879A3 (en)
YU (1) YU298375A (en)
ZA (1) ZA757344B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en) 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
NO305125B1 (en) * 1992-05-29 1999-04-06 Lilly Industries Ltd Pharmaceutical compounds
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
WO1997016430A1 (en) * 1995-11-01 1997-05-09 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
IL134812A0 (en) 1997-09-02 2001-04-30 Yoshitomi Pharmaceutical Condensed thiophene derivatives and pharmaceutical compositions containing the same
PL199016B1 (en) * 2002-06-20 2008-08-29 Adamed Sp Z Oo Method of manufacture of alanzapine, new derivative of n-demethyl olanzapine and method of manufacture of new derivative of n-demethyl olanzapine
SI21270A (en) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Crystal forms of olanzapine and procedures for their preparation
DE10301923B3 (en) * 2003-01-17 2004-09-16 Krka Tovarna Zdravil, D.D. Process and intermediates for the production of olanzapine
AR047461A1 (en) * 2004-01-27 2006-01-18 Synthon Bv TRAINING, PURIFICATION AND USE OF N-FORMILOLANZAPINE
AR048272A1 (en) 2004-03-18 2006-04-12 Lek Pharmaceuticals SYNTHESIS OF 2 METHYL - 4- (4- METHYL -1- PIPERAZINIL) - 10 H- TIENO (2,3-B) (1,5) BENZODIAZEPIN AND ITS SALTS, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING IT AND ITS USE IN THE MANUFACTURE OF MEDICINES FOR THE TREATMENT OF MENTAL DISEASES.
ES2398694T3 (en) * 2004-06-30 2013-03-21 Athersys, Inc. Substituted azepine derivatives as serotonin receptor modulators
EP2292624A1 (en) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Process for the purification of olanzapine

Also Published As

Publication number Publication date
CS236753B2 (en) 1985-05-15
MY8200149A (en) 1982-12-31
JPS5176296A (en) 1976-07-01
SE421209B (en) 1981-12-07
IE42564B1 (en) 1980-09-10
PH11669A (en) 1978-05-19
FR2292479B1 (en) 1978-07-28
KE3163A (en) 1981-10-16
YU298375A (en) 1982-10-31
SE7812194L (en) 1978-11-27
BG29573A3 (en) 1980-12-12
DD123343A5 (en) 1976-12-12
HK58681A (en) 1981-12-04
AT351547B (en) 1979-07-25
AU506340B2 (en) 1979-12-20
IL48502A (en) 1980-01-31
FR2292479A1 (en) 1976-06-25
PL100135B1 (en) 1978-09-30
JPS6044314B2 (en) 1985-10-02
NL186088C (en) 1990-09-17
DK146887C (en) 1984-07-09
GB1533235A (en) 1978-11-22
AR221203A1 (en) 1981-01-15
IL48502A0 (en) 1976-01-30
AU8685875A (en) 1977-05-26
RO69912A (en) 1980-08-15
BE835932A (en) 1976-05-25
DK524175A (en) 1976-05-27
ES443011A1 (en) 1977-07-01
ZA757344B (en) 1976-11-24
SU629879A3 (en) 1978-10-25
PH24534A (en) 1990-08-03
DE2552403C2 (en) 1986-06-19
SE7513185L (en) 1976-05-27
HU172493B (en) 1978-09-28
CH613454A5 (en) 1979-09-28
NL7513833A (en) 1976-05-31
DE2552403A1 (en) 1976-08-12
DK146887B (en) 1984-01-30
ATA898275A (en) 1979-01-15
NZ179335A (en) 1978-11-13
SE429045B (en) 1983-08-08
CH613455A5 (en) 1979-09-28
CA1075687A (en) 1980-04-15
NL186088B (en) 1990-04-17
SU626702A3 (en) 1978-09-30

Similar Documents

Publication Publication Date Title
CA1007200A (en) Bottle carrier
IE42564L (en) Thieno-benzodiazepine derivatives
IE42109L (en) Benzimidazole-2-carbamate derivatives.
IE43567L (en) Tricyclic n-containing derivatives.
AU475718B2 (en) 9-(SUBSTITUTED AMINO) IMIDAZO [4,5-f] QUINOLINES
IE40141L (en) Benzimidazole-2-carbamate derivatives
IE38942B1 (en) Dibenzo/a,d/cycloheptene derivatives
AU473160B2 (en) 9-(SUBSTITUTED AMINO) IMIDAZO [4,5-f] QUINOLINE
YU39716B (en) Process for obtaining thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine derivatives
ZA743647B (en) 5h-<1> benzopyrano <3,4-d> pyridines
IE40169L (en) Cephalosporin derivatives
CA1013357A (en) Tricyclic arylalkylene lactamimides
IE40051B1 (en) 7-(-(cyanomethyl-aryl)-acteamido)-cephalosporins
CA1029381A (en) Process for preparing hexahydrothieno (3,4-d) imidazole-2,4-diones
AU476794B2 (en) Method for the preparation of phthalazino [2,3-b] phthalazine-5 (14h), 12(7h)-dione
IE792415L (en) Thienopyridoindoles
CA1020553A (en) Processes for purification of derivatives of 1,4-benzodiazepin-2-one
CA1016944A (en) Method for the preparation of phthalazino (2,3,-b) phthalazine-5(14h), 12(7h)-dione
IE43254L (en) Bicyclo [2,2,2] octanes.
ZA747367B (en) 3,3a-dihydro-2h,9h-isoxazolo(3,2-b) (1,3) benzoxazin-9-ones
AU6731274A (en) 11H-PYRIMIDO [4,5-b][1,4] BENZODIAZEPINES
AU478296B2 (en) SUBSTITUTED DIBENZO [b,f] THIEPINS
AU488550B2 (en) Novel 4h-s-triazolo [4,3-a] [1,5] benzodiazepin-5-ones
IE42565L (en) Thieno [1,5] benzodiazepine intermediates
AU457549B2 (en) 4h-s-triazalo 4,3-2 [1,4] benzodiazepines