ES407730A1 - Un procedimiento para preparar nuevas pirimidinonas. - Google Patents

Un procedimiento para preparar nuevas pirimidinonas.

Info

Publication number
ES407730A1
ES407730A1 ES407730A ES407730A ES407730A1 ES 407730 A1 ES407730 A1 ES 407730A1 ES 407730 A ES407730 A ES 407730A ES 407730 A ES407730 A ES 407730A ES 407730 A1 ES407730 A1 ES 407730A1
Authority
ES
Spain
Prior art keywords
methyl
hydrogen
formula
see formula
pyrimidinones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES407730A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES407730A1 publication Critical patent/ES407730A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES407730A 1971-10-29 1972-10-18 Un procedimiento para preparar nuevas pirimidinonas. Expired ES407730A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (1)

Publication Number Publication Date
ES407730A1 true ES407730A1 (es) 1976-01-16

Family

ID=22715935

Family Applications (2)

Application Number Title Priority Date Filing Date
ES407730A Expired ES407730A1 (es) 1971-10-29 1972-10-18 Un procedimiento para preparar nuevas pirimidinonas.
ES436624A Expired ES436624A1 (es) 1971-10-29 1975-04-15 Un procedimiento para preparar nuevas hidroxipirmidinas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES436624A Expired ES436624A1 (es) 1971-10-29 1975-04-15 Un procedimiento para preparar nuevas hidroxipirmidinas.

Country Status (25)

Country Link
JP (2) JPS5337870B2 (sv)
AR (2) AR198798A1 (sv)
AT (2) AT320656B (sv)
AU (1) AU467600B2 (sv)
BE (1) BE790125A (sv)
CA (1) CA980778A (sv)
CH (2) CH549579A (sv)
DE (3) DE2264374C3 (sv)
DK (1) DK131465B (sv)
EG (1) EG11013A (sv)
ES (2) ES407730A1 (sv)
FI (1) FI55503C (sv)
FR (1) FR2157865B1 (sv)
GB (2) GB1377308A (sv)
IE (1) IE37043B1 (sv)
IL (2) IL40458A (sv)
LU (1) LU66304A1 (sv)
NL (1) NL166470C (sv)
NO (1) NO136574C (sv)
PH (2) PH10129A (sv)
PL (2) PL84634B1 (sv)
SE (2) SE393376B (sv)
SU (2) SU498908A3 (sv)
YU (2) YU35125B (sv)
ZA (1) ZA727362B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (sv) * 1979-04-17 1980-11-01
JPS5752409Y2 (sv) * 1979-11-05 1982-11-15
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 p−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
US7776870B2 (en) 2005-08-22 2010-08-17 Melior Pharmaceuticals I, Inc. Methods for modulating Lyn kinase activity and treating related disorders
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
US10786503B2 (en) 2017-04-10 2020-09-29 Melior Pharmaceuticals I, Inc. Treatment of adipocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951431A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
SE393376B (sv) 1977-05-09
DK131465C (sv) 1975-12-08
DE2248741B2 (de) 1974-11-14
AT321308B (de) 1975-03-25
NO136574B (sv) 1977-06-20
DE2248741A1 (de) 1973-05-03
PL89852B1 (sv) 1976-12-31
FR2157865B1 (sv) 1975-10-31
JPS4852780A (sv) 1973-07-24
PL84634B1 (sv) 1976-04-30
AT320656B (de) 1975-02-25
YU99179A (en) 1981-08-31
SU505362A3 (ru) 1976-02-28
SE397090B (sv) 1977-10-17
YU36295B (en) 1982-06-18
DE2264657A1 (de) 1974-06-20
NO136574C (no) 1977-09-28
DK131465B (da) 1975-07-21
PH11594A (en) 1978-03-31
YU255172A (en) 1980-03-15
AR198798A1 (es) 1974-07-24
ZA727362B (en) 1973-11-28
FI55503C (fi) 1979-08-10
AR196263A1 (es) 1973-12-10
EG11013A (en) 1976-11-30
DE2264374A1 (de) 1973-05-24
LU66304A1 (sv) 1973-05-03
IE37043B1 (en) 1977-04-27
ES436624A1 (es) 1977-02-01
SU498908A3 (ru) 1976-01-05
AU4722872A (en) 1974-04-04
DE2264657C2 (de) 1982-09-16
BE790125A (fr) 1973-04-16
IL48790A (en) 1976-05-31
NL7213959A (sv) 1973-05-02
PH10129A (en) 1976-09-02
JPS5337870B2 (sv) 1978-10-12
GB1377308A (en) 1974-12-11
JPS5422995B2 (sv) 1979-08-10
DE2264374B2 (de) 1980-08-07
DE2248741C3 (de) 1975-06-26
FI55503B (fi) 1979-04-30
AU467600B2 (en) 1975-12-04
IE37043L (en) 1973-04-29
JPS53116386A (en) 1978-10-11
CA980778A (en) 1975-12-30
IL40458A (en) 1976-05-31
CH555832A (fr) 1974-11-15
GB1377720A (en) 1974-12-18
YU35125B (en) 1980-09-25
FR2157865A1 (sv) 1973-06-08
SE7505279L (sv) 1975-05-06
CH549579A (fr) 1974-05-31
DE2264374C3 (de) 1981-07-23
IL48790A0 (en) 1976-03-31
NL166470B (nl) 1981-03-16
IL40458A0 (en) 1972-11-28
NL166470C (nl) 1981-08-17

Similar Documents

Publication Publication Date Title
ES391299A1 (es) Procedimiento para la preparacion de n-alil 2 - arilamino -imidazolinas (2) sustituidas.
ES405983A1 (es) Procedimiento para la preparacion de derivados de fenileti-lamina fluoralcohilados.
ES407730A1 (es) Un procedimiento para preparar nuevas pirimidinonas.
ES405982A1 (es) Procedimiento para la preparacion de 4-aza-bencimidazoles.
ES411341A1 (es) Procedimiento para la preparacion de compuestos heteroci- clicos sustituidos por un radical guanidinilideno.
ES397370A1 (es) Procedimiento para la preparacion de un compuesto tranqui- lizante.
ES389360A1 (es) Procedimiento para la preparacion de acidos ariloxi- o bienariltioalcanicos.
ES421068A1 (es) Procedimiento para la preparacion de nuevas 2-fenilamino- imidazolinas sustituidas.
ES450380A1 (es) Procedimiento para preparar derivados de acido indanacetico.
ES418113A1 (es) Un procedimiento para la preparacion de nuevas piperacino- pirimidinas.
ES423958A1 (es) Procedimiento para la obtencion de derivados del indol.
ES427454A1 (es) Procedimiento para la preparacion de 2-carbalcoxi-amino- bencimidazol-5-(6)-fenileteres.
ES425216A1 (es) Procedimiento para la preparacion de nuevas triazolo - 1,5 - benzodiazepinas sustituidas.
ES419739A1 (es) Procedimiento para la preparacion de 2-arilamino-imidazoli-nas (2) sustituidas.
ES448390A1 (es) Procedimiento para la preparacion de isoriazolilureas susti-tuidas.
ES410313A2 (es) Procedimiento para lapreparacion de 6,7-dimetoxi-quinazoli-nonas.
ES419019A1 (es) Procedimiento para la preparacion de compuestos polici- clicos.
ES430587A1 (es) Procedimiento para la preparacion de 4 amino-3,5-dihalogeno-feniletanolaminas.
ES424486A1 (es) Un procedimiento para preparar tiadiazolilimidazolidinonas.
ES401342A1 (es) Procedimiento para la preparacion de nuevos derivados de lapiridina y de sus sales.
ES451375A1 (es) Procedimiento para la preparacion de 2-4 diamino-5-bencil-pirimidinas.
ES411737A1 (es) Procedimiento para la preparacion de compuestos heteroci- clicos binucleares.
ES390275A1 (es) Un procedimiento para la preparacion de 1,2-dialquil (infe-rior) pirrolidinas.
ES428624A1 (es) Procedimiento para la preparacion de derivados de la pirimi-dina.
ES356092A1 (es) Un procedimiento para la preparacion de derivados de acido 2-naftilacetico 5-sustituidos.