ES425216A1 - Procedimiento para la preparacion de nuevas triazolo - 1,5 - benzodiazepinas sustituidas. - Google Patents
Procedimiento para la preparacion de nuevas triazolo - 1,5 - benzodiazepinas sustituidas.Info
- Publication number
- ES425216A1 ES425216A1 ES425216A ES425216A ES425216A1 ES 425216 A1 ES425216 A1 ES 425216A1 ES 425216 A ES425216 A ES 425216A ES 425216 A ES425216 A ES 425216A ES 425216 A1 ES425216 A1 ES 425216A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- carbon atoms
- general formula
- trifluoromethyl
- chlorine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940049706 benzodiazepine Drugs 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- -1 nitro, methyl Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2318673A DE2318673A1 (de) | 1973-04-13 | 1973-04-13 | Neue substituierte triazolo-1,5benzodiazepine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES425216A1 true ES425216A1 (es) | 1976-05-16 |
Family
ID=5877963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES425216A Expired ES425216A1 (es) | 1973-04-13 | 1974-04-10 | Procedimiento para la preparacion de nuevas triazolo - 1,5 - benzodiazepinas sustituidas. |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5753797B2 (es) |
| AT (1) | AT336025B (es) |
| BE (1) | BE813677A (es) |
| CH (1) | CH591486A5 (es) |
| DE (1) | DE2318673A1 (es) |
| DK (1) | DK136821C (es) |
| ES (1) | ES425216A1 (es) |
| FI (1) | FI56837C (es) |
| FR (1) | FR2225164B1 (es) |
| GB (1) | GB1462095A (es) |
| NL (1) | NL7404884A (es) |
| NO (1) | NO140860C (es) |
| SE (1) | SE419989B (es) |
| SU (1) | SU730307A3 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4080323A (en) * | 1977-03-07 | 1978-03-21 | Hoffmann-La Roche Inc. | Imidazo [1,5-a][1,5] benzodiazepines |
| US4118386A (en) * | 1977-04-04 | 1978-10-03 | Hoffmann-La Roche Inc. | Synthesis of imidazo[1,5-a]diazepine-3-carboxylates |
| DE3435972A1 (de) * | 1984-10-01 | 1986-04-10 | Boehringer Ingelheim KG, 6507 Ingelheim | Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung |
| KR100840852B1 (ko) * | 2004-05-25 | 2008-06-23 | 화이자 프로덕츠 인크. | 테트라아자벤조[ｅ]아줄렌 유도체 및 이의 유사체 |
| BRPI0510273A (pt) | 2004-05-25 | 2007-10-30 | Pfizer Prod Inc | derivados de tetraazabenzo[e]azuleno e análogos destes |
| DE102005061840A1 (de) | 2005-12-23 | 2007-06-28 | Merck Patent Gmbh | Triazolderivate |
| DE102006051796A1 (de) * | 2006-11-03 | 2008-05-08 | Merck Patent Gmbh | Triaza-benzo[e]azulenderivate |
-
1973
- 1973-04-13 DE DE2318673A patent/DE2318673A1/de not_active Withdrawn
-
1974
- 1974-03-26 AT AT248274A patent/AT336025B/de not_active IP Right Cessation
- 1974-04-09 CH CH493674A patent/CH591486A5/xx not_active IP Right Cessation
- 1974-04-09 FI FI1070/74A patent/FI56837C/fi active
- 1974-04-10 NO NO741351A patent/NO140860C/no unknown
- 1974-04-10 ES ES425216A patent/ES425216A1/es not_active Expired
- 1974-04-10 DK DK202474A patent/DK136821C/da not_active IP Right Cessation
- 1974-04-10 NL NL7404884A patent/NL7404884A/xx not_active Application Discontinuation
- 1974-04-10 JP JP49040676A patent/JPS5753797B2/ja not_active Expired
- 1974-04-11 SE SE7405021A patent/SE419989B/xx unknown
- 1974-04-11 SU SU742015007A patent/SU730307A3/ru active
- 1974-04-11 GB GB1633474A patent/GB1462095A/en not_active Expired
- 1974-04-12 BE BE143167A patent/BE813677A/xx not_active IP Right Cessation
- 1974-04-12 FR FR7413023A patent/FR2225164B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL7404884A (es) | 1974-10-15 |
| FI56837C (fi) | 1980-04-10 |
| GB1462095A (en) | 1977-01-19 |
| FR2225164A1 (es) | 1974-11-08 |
| ATA248274A (de) | 1976-08-15 |
| JPS5052093A (es) | 1975-05-09 |
| DE2318673A1 (de) | 1974-11-07 |
| AT336025B (de) | 1977-04-12 |
| NO140860B (no) | 1979-08-20 |
| FR2225164B1 (es) | 1977-05-06 |
| FI56837B (fi) | 1979-12-31 |
| SE419989B (sv) | 1981-09-07 |
| BE813677A (fr) | 1974-10-14 |
| NO741351L (no) | 1974-10-15 |
| JPS5753797B2 (es) | 1982-11-15 |
| DK136821B (da) | 1977-11-28 |
| DK136821C (da) | 1978-05-08 |
| SU730307A3 (ru) | 1980-04-25 |
| NO140860C (no) | 1979-11-28 |
| CH591486A5 (es) | 1977-09-30 |
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