ES2952834T3 - Lipoil-Glu-Ala para el tratamiento de daño neurodegenerativo producido por traumatismo craneoencefálico - Google Patents
Lipoil-Glu-Ala para el tratamiento de daño neurodegenerativo producido por traumatismo craneoencefálico Download PDFInfo
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- ES2952834T3 ES2952834T3 ES18724073T ES18724073T ES2952834T3 ES 2952834 T3 ES2952834 T3 ES 2952834T3 ES 18724073 T ES18724073 T ES 18724073T ES 18724073 T ES18724073 T ES 18724073T ES 2952834 T3 ES2952834 T3 ES 2952834T3
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Classifications
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- A61K31/33—Heterocyclic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- General Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| US201762489735P | 2017-04-25 | 2017-04-25 | |
| PCT/US2018/029372 WO2018200680A1 (en) | 2017-04-25 | 2018-04-25 | Compositions and methods for treating traumatic brain injury |
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| ES2952834T3 true ES2952834T3 (es) | 2023-11-06 |
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| US20240124520A1 (en) * | 2019-10-16 | 2024-04-18 | The Board Of Trustees Of The Leland Stanford Junior University | N-acylated histidine dipeptides as anticancer agents |
| CN116199666B (zh) * | 2023-03-07 | 2025-02-28 | 中国药科大学 | 两亲性化合物及其药物组合物 |
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| DE1047991B (de) | 1957-11-20 | 1958-12-31 | Nordmark Werke Gmbh | Verfahren zur Herstellung chemisch stabiler, untoxischer, steriler Injektionsloesungen von Thioctsaeure |
| US3875207A (en) | 1967-01-25 | 1975-04-01 | Ciba Geigy Corp | Process for the temporary protection of amino groups in peptide syntheses |
| US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| CA1219824A (en) | 1981-04-17 | 1987-03-31 | David C. Ward | Modified nucleotides and methods of preparing and using same |
| US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
| US5288706A (en) | 1987-12-25 | 1994-02-22 | Mitsui Toatsu Chemicals, Incorporated | Medicament for prevention and remedy of diseases of the pancreas and others |
| US5039660A (en) | 1988-03-02 | 1991-08-13 | Endocon, Inc. | Partially fused peptide pellet |
| FR2653334B1 (fr) | 1989-10-19 | 1991-12-20 | Erphar Ste Civile | Preparation cosmetique de bronzage. |
| DE59010810D1 (de) | 1989-11-09 | 1998-04-16 | Asta Medica Ag | Arzneimittel enthaltend als Wirkstoff R-alpha-Liponsäure oder S-alpha-Liponsäure |
| DE4000397A1 (de) | 1990-01-09 | 1991-07-11 | Hoechst Ag | Lipidselektive antioxidantien sowie deren herstellung und verwendung |
| CA2118496C (en) | 1992-04-24 | 2005-01-11 | Roger Randall Charles New | Method of reducing microorganism adhesion |
| DE4235912C2 (de) | 1992-10-23 | 2002-12-05 | Viatris Gmbh | Verfahren zur Herstellung kristalliner Thioctsäure und deren Verwendung |
| DE4433764A1 (de) | 1994-09-22 | 1996-03-28 | Asta Medica Ag | Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit |
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-
2018
- 2018-04-25 AU AU2018258158A patent/AU2018258158A1/en not_active Abandoned
- 2018-04-25 CA CA3061203A patent/CA3061203A1/en active Pending
- 2018-04-25 EP EP23173043.3A patent/EP4282411A1/en not_active Withdrawn
- 2018-04-25 JP JP2019559073A patent/JP7203756B2/ja active Active
- 2018-04-25 US US15/962,575 patent/US10744115B2/en active Active
- 2018-04-25 WO PCT/US2018/029372 patent/WO2018200680A1/en not_active Ceased
- 2018-04-25 CN CN201880040029.9A patent/CN110913851B/zh not_active Expired - Fee Related
- 2018-04-25 ES ES18724073T patent/ES2952834T3/es active Active
- 2018-04-25 EP EP18724073.4A patent/EP3615023B1/en active Active
- 2018-04-25 DK DK18724073.4T patent/DK3615023T3/da active
-
2020
- 2020-07-30 US US16/943,088 patent/US11213509B2/en not_active Expired - Fee Related
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2021
- 2021-12-15 US US17/644,459 patent/US20220280477A1/en not_active Abandoned
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2022
- 2022-12-27 JP JP2022209797A patent/JP2023030158A/ja active Pending
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2024
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2024202147A1 (en) | 2024-05-02 |
| AU2018258158A1 (en) | 2019-11-21 |
| JP7203756B2 (ja) | 2023-01-13 |
| JP2023030158A (ja) | 2023-03-07 |
| CN110913851A (zh) | 2020-03-24 |
| US11213509B2 (en) | 2022-01-04 |
| WO2018200680A1 (en) | 2018-11-01 |
| US10744115B2 (en) | 2020-08-18 |
| EP3615023A1 (en) | 2020-03-04 |
| DK3615023T3 (da) | 2023-09-25 |
| US20220280477A1 (en) | 2022-09-08 |
| EP3615023B1 (en) | 2023-06-21 |
| CN110913851B (zh) | 2023-08-25 |
| EP4282411A1 (en) | 2023-11-29 |
| JP2020517731A (ja) | 2020-06-18 |
| CA3061203A1 (en) | 2018-11-01 |
| US20200352904A1 (en) | 2020-11-12 |
| US20180303796A1 (en) | 2018-10-25 |
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