JP7203756B2 - 外傷性脳傷害を治療するための組成物および方法 - Google Patents
外傷性脳傷害を治療するための組成物および方法 Download PDFInfo
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K31/4164—1,3-Diazoles
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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| US20240124520A1 (en) * | 2019-10-16 | 2024-04-18 | The Board Of Trustees Of The Leland Stanford Junior University | N-acylated histidine dipeptides as anticancer agents |
| CN116199666B (zh) * | 2023-03-07 | 2025-02-28 | 中国药科大学 | 两亲性化合物及其药物组合物 |
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-
2018
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- 2018-04-25 WO PCT/US2018/029372 patent/WO2018200680A1/en not_active Ceased
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2020
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2021
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2022
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2024
- 2024-04-03 AU AU2024202147A patent/AU2024202147A1/en not_active Abandoned
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| Kates, S. A. et al.，Lipoic acid analogs with enhanced pharmacological activity，Bioorganic & Medicinal Chemistry，2014年，Vol.22, No.1，p.505-512，doi:10.1016/j.bmc.2013.10.057 |
| Kates, S. A. et al.，Pre-clinical and Clinical Safety Studies of CMX-2043: a cytoprotective lipoic acid analogue for ischaemia-reperfusion injury，Basic & Clinical Pharmacology & Toxicology，2014年，Vol.115, No.5，p.456-464，doi:10.1111/bcpt.12254 |
| Ozbal, S. et al.，The effects of α-lipoic acid on immature rats with traumatic brain injury，Biotechnic & Histochemistry，2015年，Vol.90, No.3，p.206-215，doi:10.3109/10520295.2014.977950 |
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| AU2024202147A1 (en) | 2024-05-02 |
| AU2018258158A1 (en) | 2019-11-21 |
| JP2023030158A (ja) | 2023-03-07 |
| CN110913851A (zh) | 2020-03-24 |
| US11213509B2 (en) | 2022-01-04 |
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| US10744115B2 (en) | 2020-08-18 |
| EP3615023A1 (en) | 2020-03-04 |
| DK3615023T3 (da) | 2023-09-25 |
| US20220280477A1 (en) | 2022-09-08 |
| EP3615023B1 (en) | 2023-06-21 |
| ES2952834T3 (es) | 2023-11-06 |
| CN110913851B (zh) | 2023-08-25 |
| EP4282411A1 (en) | 2023-11-29 |
| JP2020517731A (ja) | 2020-06-18 |
| CA3061203A1 (en) | 2018-11-01 |
| US20200352904A1 (en) | 2020-11-12 |
| US20180303796A1 (en) | 2018-10-25 |
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