ES2920510T3 - Vectores de selección novedosos y métodos para seleccionar células hospedadoras eucariotas - Google Patents
Vectores de selección novedosos y métodos para seleccionar células hospedadoras eucariotas Download PDFInfo
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
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- C—CHEMISTRY; METALLURGY
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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Landscapes
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| EP3521435A1 (en) | 2018-02-06 | 2019-08-07 | Bayer AG | A high stringency selection system for protein expression in proline-auxotrophic cells |
| JP2021536263A (ja) * | 2018-09-07 | 2021-12-27 | メディミューン，エルエルシー | 細胞選択の方法 |
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| US7384744B2 (en) | 2002-11-29 | 2008-06-10 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | Expression vector, methods for the production of heterologous gene products and for the selection of recombinant cells producing high levels of such products |
| ES2309508T3 (es) * | 2003-03-11 | 2008-12-16 | Laboratoires Serono Sa | Vectores de expresion que comprenden el promotor de mcmv-ie2. |
| DK1716233T3 (da) | 2004-01-30 | 2009-10-26 | Maxygen Holdings Ltd | Reguleret stopkodongennemlæsning |
| US20060275794A1 (en) | 2005-03-07 | 2006-12-07 | Invitrogen Corporation | Collections of matched biological reagents and methods for identifying matched reagents |
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| BRPI0712073B8 (pt) | 2006-05-17 | 2021-05-25 | Hoffmann La Roche | ácido nucléico para produção de um polipeptídio ou proteína heteróloga |
| CN103805633B (zh) * | 2007-12-21 | 2016-09-07 | 诺华股份有限公司 | 有机化合物 |
| EP3075858B1 (en) | 2007-12-21 | 2020-01-29 | Novartis Ag | Mammalian expression vector |
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| WO2010029130A1 (en) | 2008-09-10 | 2010-03-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Neuronal viability factor and use thereof |
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| US9534226B2 (en) | 2009-02-27 | 2017-01-03 | Novartis Ag | Expression vector system comprising two selection markers |
| CN102030754B (zh) * | 2009-09-28 | 2013-07-10 | 中国科学院微生物研究所 | 非病毒载体及其制备方法与应用 |
| PL3027646T3 (pl) | 2013-07-31 | 2019-03-29 | Novartis Ag | Nowe wektory selekcyjne i sposoby selekcji eukariotycznych komórek gospodarza |
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