ES2919345T3 - Variante de la acetohidroxiácido sintasa, microorganismo que comprende la misma, y método para producir L-aminoácidos de cadena ramificada mediante el uso del mismo - Google Patents
Variante de la acetohidroxiácido sintasa, microorganismo que comprende la misma, y método para producir L-aminoácidos de cadena ramificada mediante el uso del mismo Download PDFInfo
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- ES2919345T3 ES2919345T3 ES18832634T ES18832634T ES2919345T3 ES 2919345 T3 ES2919345 T3 ES 2919345T3 ES 18832634 T ES18832634 T ES 18832634T ES 18832634 T ES18832634 T ES 18832634T ES 2919345 T3 ES2919345 T3 ES 2919345T3
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C12P13/04—Alpha- or beta- amino acids
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| PCT/KR2018/007821 WO2019013532A2 (ko) | 2017-07-11 | 2018-07-10 | 아세토하이드록시산 신타아제 변이체, 이를 포함하는 미생물 또는 이를 이용하는 l-분지쇄 아미노산 생산 방법 |
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| KR102311391B1 (ko) * | 2020-05-21 | 2021-10-12 | 씨제이제일제당 주식회사 | L- 분지쇄 아미노산 생산능이 강화된 미생물 및 이를 이용하여 l-분지쇄 아미노산을 생산하는 방법 |
| CN112195204B (zh) * | 2020-10-21 | 2022-04-15 | 通辽梅花生物科技有限公司 | 一种混菌发酵生产支链氨基酸的方法 |
| KR102619598B1 (ko) * | 2021-08-23 | 2023-12-29 | 씨제이제일제당 주식회사 | 신규한 아세토하이드록시산 신타아제 소단위체 변이체 및 이를 이용한 l-발린 생산 방법 |
| KR102935702B1 (ko) * | 2022-12-28 | 2026-03-09 | 씨제이제일제당 주식회사 | 신규한 아세토락테이트 합성효소 활성을 갖는 변이체 폴리펩티드 및 이를 이용한 l-글루탐산 생산 방법 |
| CN121532502A (zh) * | 2023-05-19 | 2026-02-13 | Cj第一制糖株式会社 | 变体多肽和使用其生产l-缬氨酸的方法 |
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| KR100815041B1 (ko) | 1999-08-02 | 2008-03-18 | 아처 다니엘 미드랜드 캄파니 | 아미노산 생산의 대사 공학 |
| JP4623825B2 (ja) | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
| EP1491634A1 (en) | 2003-06-26 | 2004-12-29 | Degussa AG | Feedback resistant acetohydroxy acid synthetase mutants |
| KR100671167B1 (ko) | 2005-09-12 | 2007-01-19 | 이상익 | 개인용 긴급 구난 벨트 |
| WO2007149069A2 (en) | 2006-06-15 | 2007-12-27 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Resistance to acetolactate synthase-inhibiting herbicides |
| RU2355763C2 (ru) * | 2006-09-13 | 2009-05-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | Мутантная ацетолактатсинтаза и способ продукции разветвленных l-аминокислот |
| BRPI0716980A2 (pt) | 2006-09-15 | 2013-10-22 | Cj Cheiljedang Corp | Corynebacteria com produtividade de l-lisina aumentada e método de produção da l-lisina usando a mesma |
| PL2203565T3 (pl) | 2007-10-05 | 2016-02-29 | Cibus Europe Bv | Zmutowane geny syntazy kwasu acetohydroksy roślin kapustnych |
| EP2582815B1 (en) * | 2010-06-15 | 2016-08-10 | Daesang Corp. | Production process for amino acids of the aspartate family using microorganisms |
| CN102286505B (zh) * | 2011-05-26 | 2013-04-03 | 江南大学 | 用于发酵生产l-缬氨酸的重组dna、菌株及方法 |
| KR101117022B1 (ko) | 2011-08-16 | 2012-03-16 | 씨제이제일제당 (주) | L-발린 생산능이 향상된 미생물 및 이를 이용한 l-발린 제조방법 |
| US9290770B2 (en) * | 2011-08-22 | 2016-03-22 | Research Institute Of Innovative Technology For The Earth | Coryneform bacterium transformant and process for producing valine using the same |
| KR101721722B1 (ko) * | 2013-03-11 | 2017-04-10 | 씨제이제일제당 (주) | L-발린 생산능이 향상된 균주 및 이를 이용한 l-발린 생산방법 |
| DK2811028T3 (en) | 2013-06-03 | 2017-05-01 | Evonik Degussa Gmbh | Process for Preparation of L-Valine Using Recombinant Coryn Bacteria Containing the Propionate Inducible IlvBN Operon |
| KR20150119785A (ko) | 2014-04-15 | 2015-10-26 | 삼성전자주식회사 | 라이프 로그 서비스 제공 시스템 및 그 서비스 방법 |
| KR101720836B1 (ko) * | 2014-08-05 | 2017-04-03 | 씨제이제일제당 (주) | 피드백 저항성 아세토하이드록시산 신타아제 변이체 및 이를 이용한 l-발린의 생산방법 |
| KR101796830B1 (ko) | 2015-08-25 | 2017-11-13 | 씨제이제일제당 (주) | L-류신 생산능을 가지는 미생물 및 이를 이용한 l-류신의 제조방법 |
| CN106754807B (zh) * | 2016-12-29 | 2020-10-30 | 廊坊梅花生物技术开发有限公司 | 生产l-亮氨酸菌株和生产l-亮氨酸的方法 |
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2017
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- 2018-07-10 WO PCT/KR2018/007821 patent/WO2019013532A2/ko not_active Ceased
- 2018-07-10 MX MX2019015056A patent/MX2019015056A/es unknown
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| CN110724679B (zh) | 2022-01-11 |
| EP3553171A2 (en) | 2019-10-16 |
| BR112019020183A2 (pt) | 2020-06-02 |
| US20200263149A1 (en) | 2020-08-20 |
| CN110506112B (zh) | 2021-06-08 |
| JP2020505023A (ja) | 2020-02-20 |
| WO2019013532A2 (ko) | 2019-01-17 |
| CN110506112A (zh) | 2019-11-26 |
| ZA201908353B (en) | 2021-04-28 |
| CA3064569A1 (en) | 2019-01-17 |
| RU2743964C1 (ru) | 2021-03-01 |
| EP3553171B1 (en) | 2022-05-04 |
| WO2019013532A3 (ko) | 2019-04-04 |
| AU2018301879B2 (en) | 2022-02-17 |
| US11085029B2 (en) | 2021-08-10 |
| BR112019020183B1 (pt) | 2023-03-21 |
| EP3553171A4 (en) | 2020-05-13 |
| CN110724679A (zh) | 2020-01-24 |
| US20210040457A1 (en) | 2021-02-11 |
| KR101996129B1 (ko) | 2019-07-04 |
| JP6794555B2 (ja) | 2020-12-02 |
| MX2019015056A (es) | 2020-08-03 |
| US10844359B2 (en) | 2020-11-24 |
| US11345901B2 (en) | 2022-05-31 |
| AU2018301879A1 (en) | 2020-01-16 |
| KR20190007142A (ko) | 2019-01-22 |
| US20210324349A1 (en) | 2021-10-21 |
| CA3064569C (en) | 2023-03-14 |
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