ES2867900T3 - Anticuerpos y polipéptidos dirigidos contra CD127 - Google Patents
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Diabetes (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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Applications Claiming Priority (2)
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EP16306655 | 2016-12-09 | ||
PCT/EP2017/081911 WO2018104483A1 (fr) | 2016-12-09 | 2017-12-07 | Anticorps et polypeptides dirigés contre cd127 |
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Publication Number | Publication Date |
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ES2867900T3 true ES2867900T3 (es) | 2021-10-21 |
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ES17835592T Active ES2867900T3 (es) | 2016-12-09 | 2017-12-07 | Anticuerpos y polipéptidos dirigidos contra CD127 |
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US (2) | US11098128B2 (fr) |
EP (1) | EP3551664B1 (fr) |
JP (1) | JP6986559B2 (fr) |
KR (1) | KR102306366B1 (fr) |
CN (1) | CN110392695B (fr) |
AR (1) | AR110326A1 (fr) |
AU (1) | AU2017373819B2 (fr) |
BR (1) | BR112019010595A2 (fr) |
CA (1) | CA3042582C (fr) |
CL (1) | CL2019001530A1 (fr) |
CO (1) | CO2019005909A2 (fr) |
CR (1) | CR20190273A (fr) |
CY (1) | CY1124153T1 (fr) |
DK (1) | DK3551664T3 (fr) |
EA (1) | EA201991005A1 (fr) |
ES (1) | ES2867900T3 (fr) |
HR (1) | HRP20210697T1 (fr) |
HU (1) | HUE054206T2 (fr) |
IL (1) | IL266837B (fr) |
LT (1) | LT3551664T (fr) |
MA (1) | MA49727B1 (fr) |
MD (1) | MD3551664T2 (fr) |
MX (1) | MX2019006577A (fr) |
MY (1) | MY190770A (fr) |
NZ (1) | NZ753213A (fr) |
PE (1) | PE20191152A1 (fr) |
PH (1) | PH12019501285A1 (fr) |
PL (1) | PL3551664T3 (fr) |
PT (1) | PT3551664T (fr) |
RS (1) | RS61808B1 (fr) |
RU (1) | RU2769352C2 (fr) |
SA (1) | SA519401906B1 (fr) |
SI (1) | SI3551664T1 (fr) |
TW (1) | TWI777996B (fr) |
UA (1) | UA126386C2 (fr) |
UY (1) | UY37511A (fr) |
WO (1) | WO2018104483A1 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2017125578A1 (fr) | 2016-01-21 | 2017-07-27 | Vhsquared Limited | Polypeptides |
US12016900B2 (en) | 2017-06-04 | 2024-06-25 | Rappaport Family Institute For Research In The Medical Sciences | Method of treating cancer with an immune checkpoint inhibitor in combination with another therapeutic agent |
JP7348074B2 (ja) | 2017-06-04 | 2023-09-20 | ラパポート・ファミリー・インスティテュート・フォー・リサーチ・イン・ザ・メディカル・サイエンシーズ | がん治療に対する個別化応答の予測方法およびそのキット |
US12070489B2 (en) | 2018-12-12 | 2024-08-27 | Rappaport Family Institute For Research In The Medical Sciences | Method of treating cancer with a cancer therapy in combination with another therapeutic agent |
MX2021008796A (es) * | 2019-01-22 | 2021-11-12 | Bristol Myers Squibb Co | Anticuerpos contra subunidad alfa il-7r y usos de estos. |
AU2020294980A1 (en) | 2019-06-21 | 2022-02-17 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
EP3986931A1 (fr) | 2019-06-21 | 2022-04-27 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
BR112022008744A2 (pt) | 2019-11-05 | 2022-07-19 | Medikine Inc | Ligante de il-2rss, ligante de il-2r¿c, composto de ligação a il-2r¿¿c, composição farmacêutica, método para tratar uma doença em um paciente, método para expandir células imunes, método de uma terapia celular, método para reforçar uma vacina, método para modificar a resposta imune e ácido nucleico |
CN110894237B (zh) * | 2019-12-05 | 2021-08-03 | 山东省分析测试中心 | 抗cd127的抗体、分泌该抗体的细胞株及其制备方法和应用 |
BR112022015002A2 (pt) | 2020-02-03 | 2022-12-06 | Medikine Inc | Ligante de il-7r-alfa/gama/c, composto, composição farmacêutica, método para tratar uma doença em um paciente e ácido nucleico |
US20220389104A1 (en) | 2021-05-28 | 2022-12-08 | Ose Immunotherapeutics | Method for Treating CD127-Positive Cancers by Administering an Anti-CD127 Agent |
CN113501499A (zh) * | 2021-08-11 | 2021-10-15 | 无锡贝塔医药科技有限公司 | 一种高纯无水溴化氘气体的制备方法及其应用 |
US11999771B2 (en) | 2022-04-07 | 2024-06-04 | Medikine, Inc. | IL-7Rαγc ligand immunoglobulin fusion proteins |
WO2023232826A1 (fr) | 2022-05-30 | 2023-12-07 | Ose Immunotherapeutics | Biomarqueurs de l'activité du modulateur de l'il7r |
Family Cites Families (6)
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UY32038A (es) * | 2008-08-08 | 2010-03-26 | Glaxo Wellcome Mfg Pte Ltd | Inmunoblobulinas anti-cd127 y sus usos |
AU2011209713B2 (en) * | 2010-01-28 | 2014-04-03 | Glaxo Group Limited | CD127 binding proteins |
AR080291A1 (es) * | 2010-02-24 | 2012-03-28 | Rinat Neuroscience Corp | Anticuerpos antagonistas anti receptor de il-7 y procedimientos |
EP2583980A1 (fr) | 2011-10-19 | 2013-04-24 | Effimune | Anticorps dirigés contre la chaîne alpha du récepteur IL7, leur utilisation pour la préparation de candidats médicaments |
EP2955196A1 (fr) | 2014-06-10 | 2015-12-16 | Effimune | Anticorps dirigés contre CD127 |
GB201506869D0 (en) * | 2015-04-22 | 2015-06-03 | Ucb Biopharma Sprl | Method |
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2017
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2021
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