ES2856867T3 - Compuestos de carbamoilpiridona policíclicos y su uso para el tratamiento de infecciones por VIH - Google Patents

Compuestos de carbamoilpiridona policíclicos y su uso para el tratamiento de infecciones por VIH Download PDF

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Publication number
ES2856867T3
ES2856867T3 ES17177428T ES17177428T ES2856867T3 ES 2856867 T3 ES2856867 T3 ES 2856867T3 ES 17177428 T ES17177428 T ES 17177428T ES 17177428 T ES17177428 T ES 17177428T ES 2856867 T3 ES2856867 T3 ES 2856867T3
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Prior art keywords
compound
mmol
concentrated
hydrogen
pharmaceutical composition
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ES17177428T
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English (en)
Spanish (es)
Inventor
Mingzhe Ji
Teresa Alejandra Trejo Martin
Manoj C Desai
Haolun Jin
Hyung-Jung Pyun
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Gilead Sciences Inc
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Gilead Sciences Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
ES17177428T 2013-07-12 2014-07-11 Compuestos de carbamoilpiridona policíclicos y su uso para el tratamiento de infecciones por VIH Active ES2856867T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361845807P 2013-07-12 2013-07-12

Publications (1)

Publication Number Publication Date
ES2856867T3 true ES2856867T3 (es) 2021-09-28

Family

ID=51257630

Family Applications (2)

Application Number Title Priority Date Filing Date
ES17177428T Active ES2856867T3 (es) 2013-07-12 2014-07-11 Compuestos de carbamoilpiridona policíclicos y su uso para el tratamiento de infecciones por VIH
ES14745053.0T Active ES2647216T3 (es) 2013-07-12 2014-07-11 Compuestos policíclicos de carbamoilpiridona y su uso farmacéutico

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES14745053.0T Active ES2647216T3 (es) 2013-07-12 2014-07-11 Compuestos policíclicos de carbamoilpiridona y su uso farmacéutico

Country Status (18)

Country Link
US (6) US9458159B2 (en:Method)
EP (2) EP3252053B1 (en:Method)
JP (1) JP6411492B2 (en:Method)
AU (3) AU2014286995B2 (en:Method)
CA (1) CA2918055C (en:Method)
CY (1) CY1119545T1 (en:Method)
DK (1) DK3019499T3 (en:Method)
ES (2) ES2856867T3 (en:Method)
HR (1) HRP20171807T1 (en:Method)
HU (1) HUE037343T2 (en:Method)
LT (1) LT3019499T (en:Method)
NO (1) NO2865735T3 (en:Method)
PL (1) PL3019499T3 (en:Method)
PT (1) PT3019499T (en:Method)
RS (1) RS56539B1 (en:Method)
SI (2) SI3019499T1 (en:Method)
SM (1) SMT201700525T1 (en:Method)
WO (1) WO2015006733A1 (en:Method)

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