ES2823223T3 - Válvula transcatéter de eversión - Google Patents
Válvula transcatéter de eversión Download PDFInfo
- Publication number
- ES2823223T3 ES2823223T3 ES18204192T ES18204192T ES2823223T3 ES 2823223 T3 ES2823223 T3 ES 2823223T3 ES 18204192 T ES18204192 T ES 18204192T ES 18204192 T ES18204192 T ES 18204192T ES 2823223 T3 ES2823223 T3 ES 2823223T3
- Authority
- ES
- Spain
- Prior art keywords
- valve
- frame
- body frame
- leaflet
- configuration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000012528 membrane Substances 0.000 description 60
- 239000000463 material Substances 0.000 description 45
- 229920002313 fluoropolymer Polymers 0.000 description 39
- 239000004811 fluoropolymer Substances 0.000 description 39
- 210000004379 membrane Anatomy 0.000 description 35
- 229920001971 elastomer Polymers 0.000 description 30
- 239000000806 elastomer Substances 0.000 description 30
- 238000000034 method Methods 0.000 description 27
- 239000011148 porous material Substances 0.000 description 27
- 239000002131 composite material Substances 0.000 description 26
- 210000001519 tissue Anatomy 0.000 description 19
- 229920000295 expanded polytetrafluoroethylene Polymers 0.000 description 16
- 239000012530 fluid Substances 0.000 description 13
- 239000008280 blood Substances 0.000 description 9
- 210000004369 blood Anatomy 0.000 description 9
- 230000006870 function Effects 0.000 description 9
- 210000003709 heart valve Anatomy 0.000 description 9
- 239000000560 biocompatible material Substances 0.000 description 8
- 229920001577 copolymer Polymers 0.000 description 8
- 239000007943 implant Substances 0.000 description 8
- 239000011159 matrix material Substances 0.000 description 8
- 238000013461 design Methods 0.000 description 7
- 210000002216 heart Anatomy 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- 210000003484 anatomy Anatomy 0.000 description 6
- 230000017531 blood circulation Effects 0.000 description 6
- 208000014674 injury Diseases 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 238000005259 measurement Methods 0.000 description 6
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 6
- 239000004810 polytetrafluoroethylene Substances 0.000 description 6
- 230000008733 trauma Effects 0.000 description 6
- 238000004804 winding Methods 0.000 description 6
- BLTXWCKMNMYXEA-UHFFFAOYSA-N 1,1,2-trifluoro-2-(trifluoromethoxy)ethene Chemical compound FC(F)=C(F)OC(F)(F)F BLTXWCKMNMYXEA-UHFFFAOYSA-N 0.000 description 5
- 239000002253 acid Substances 0.000 description 5
- 150000007513 acids Chemical class 0.000 description 5
- 229920000249 biocompatible polymer Polymers 0.000 description 5
- 229920001973 fluoroelastomer Polymers 0.000 description 5
- 238000001878 scanning electron micrograph Methods 0.000 description 5
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical group FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 description 5
- RJURFGZVJUQBHK-UHFFFAOYSA-N actinomycin D Natural products CC1OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C(=O)C(C(C)C)NC(=O)C1NC(=O)C1=C(N)C(=O)C(C)=C2OC(C(C)=CC=C3C(=O)NC4C(=O)NC(C(N5CCCC5C(=O)N(C)CC(=O)N(C)C(C(C)C)C(=O)OC4C)=O)C(C)C)=C3N=C21 RJURFGZVJUQBHK-UHFFFAOYSA-N 0.000 description 4
- 239000012867 bioactive agent Substances 0.000 description 4
- 238000000576 coating method Methods 0.000 description 4
- 230000006835 compression Effects 0.000 description 4
- 238000007906 compression Methods 0.000 description 4
- 230000008878 coupling Effects 0.000 description 4
- 238000010168 coupling process Methods 0.000 description 4
- 238000005859 coupling reaction Methods 0.000 description 4
- 238000002513 implantation Methods 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- 230000000704 physical effect Effects 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- -1 polypropylene Polymers 0.000 description 4
- 238000001356 surgical procedure Methods 0.000 description 4
- 230000007704 transition Effects 0.000 description 4
- 241000283690 Bos taurus Species 0.000 description 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- 239000004743 Polypropylene Substances 0.000 description 3
- 230000001028 anti-proliverative effect Effects 0.000 description 3
- 210000001765 aortic valve Anatomy 0.000 description 3
- 238000005452 bending Methods 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 229910003460 diamond Inorganic materials 0.000 description 3
- 239000010432 diamond Substances 0.000 description 3
- 229920001519 homopolymer Polymers 0.000 description 3
- 239000003112 inhibitor Substances 0.000 description 3
- 238000001000 micrograph Methods 0.000 description 3
- 229910001000 nickel titanium Inorganic materials 0.000 description 3
- 210000003516 pericardium Anatomy 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- 229920001296 polysiloxane Polymers 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000009958 sewing Methods 0.000 description 3
- 210000005166 vasculature Anatomy 0.000 description 3
- 102100025573 1-alkyl-2-acetylglycerophosphocholine esterase Human genes 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 108010024976 Asparaginase Proteins 0.000 description 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 108010092160 Dactinomycin Proteins 0.000 description 2
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 description 2
- 102000018233 Fibroblast Growth Factor Human genes 0.000 description 2
- 108050007372 Fibroblast Growth Factor Proteins 0.000 description 2
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 description 2
- 229910000990 Ni alloy Inorganic materials 0.000 description 2
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 2
- 229960001138 acetylsalicylic acid Drugs 0.000 description 2
- RJURFGZVJUQBHK-IIXSONLDSA-N actinomycin D Chemical compound C[C@H]1OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]2CCCN2C(=O)[C@@H](C(C)C)NC(=O)[C@H]1NC(=O)C1=C(N)C(=O)C(C)=C2OC(C(C)=CC=C3C(=O)N[C@@H]4C(=O)N[C@@H](C(N5CCC[C@H]5C(=O)N(C)CC(=O)N(C)[C@@H](C(C)C)C(=O)O[C@@H]4C)=O)C(C)C)=C3N=C21 RJURFGZVJUQBHK-IIXSONLDSA-N 0.000 description 2
- 229910045601 alloy Inorganic materials 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 230000002927 anti-mitotic effect Effects 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 229940127219 anticoagulant drug Drugs 0.000 description 2
- 229940127218 antiplatelet drug Drugs 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 230000000747 cardiac effect Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- ZGDWHDKHJKZZIQ-UHFFFAOYSA-N cobalt nickel Chemical compound [Co].[Ni].[Ni].[Ni] ZGDWHDKHJKZZIQ-UHFFFAOYSA-N 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 229960000640 dactinomycin Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000013536 elastomeric material Substances 0.000 description 2
- 229940126864 fibroblast growth factor Drugs 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 210000002837 heart atrium Anatomy 0.000 description 2
- 230000000004 hemodynamic effect Effects 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- 229920000669 heparin Polymers 0.000 description 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- CFCUWKMKBJTWLW-BKHRDMLASA-N mithramycin Chemical compound O([C@@H]1C[C@@H](O[C@H](C)[C@H]1O)OC=1C=C2C=C3C[C@H]([C@@H](C(=O)C3=C(O)C2=C(O)C=1C)O[C@@H]1O[C@H](C)[C@@H](O)[C@H](O[C@@H]2O[C@H](C)[C@H](O)[C@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@@](C)(O)C3)C2)C1)[C@H](OC)C(=O)[C@@H](O)[C@@H](C)O)[C@H]1C[C@@H](O)[C@H](O)[C@@H](C)O1 CFCUWKMKBJTWLW-BKHRDMLASA-N 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 2
- 239000000106 platelet aggregation inhibitor Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229960003171 plicamycin Drugs 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 description 2
- 230000003252 repetitive effect Effects 0.000 description 2
- 238000007493 shaping process Methods 0.000 description 2
- 229960002930 sirolimus Drugs 0.000 description 2
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 229920002994 synthetic fiber Polymers 0.000 description 2
- 229920001169 thermoplastic Polymers 0.000 description 2
- 239000004416 thermosoftening plastic Substances 0.000 description 2
- WYWHKKSPHMUBEB-UHFFFAOYSA-N tioguanine Chemical compound N1C(N)=NC(=S)C2=C1N=CN2 WYWHKKSPHMUBEB-UHFFFAOYSA-N 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- FPVKHBSQESCIEP-UHFFFAOYSA-N (8S)-3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol Natural products C1C(O)C(CO)OC1N1C(NC=NCC2O)=C2N=C1 FPVKHBSQESCIEP-UHFFFAOYSA-N 0.000 description 1
- FDKXTQMXEQVLRF-ZHACJKMWSA-N (E)-dacarbazine Chemical compound CN(C)\N=N\c1[nH]cnc1C(N)=O FDKXTQMXEQVLRF-ZHACJKMWSA-N 0.000 description 1
- VSNHCAURESNICA-NJFSPNSNSA-N 1-oxidanylurea Chemical compound N[14C](=O)NO VSNHCAURESNICA-NJFSPNSNSA-N 0.000 description 1
- VHRSUDSXCMQTMA-UHFFFAOYSA-N 11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-3-one Chemical compound CC12C=CC(=O)C=C1C(C)CC1C2C(O)CC2(C)C(O)(C(=O)CO)CCC21 VHRSUDSXCMQTMA-UHFFFAOYSA-N 0.000 description 1
- FUFLCEKSBBHCMO-UHFFFAOYSA-N 11-dehydrocorticosterone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 FUFLCEKSBBHCMO-UHFFFAOYSA-N 0.000 description 1
- CTRPRMNBTVRDFH-UHFFFAOYSA-N 2-n-methyl-1,3,5-triazine-2,4,6-triamine Chemical class CNC1=NC(N)=NC(N)=N1 CTRPRMNBTVRDFH-UHFFFAOYSA-N 0.000 description 1
- 229910000619 316 stainless steel Inorganic materials 0.000 description 1
- STQGQHZAVUOBTE-UHFFFAOYSA-N 7-Cyan-hept-2t-en-4,6-diinsaeure Natural products C1=2C(O)=C3C(=O)C=4C(OC)=CC=CC=4C(=O)C3=C(O)C=2CC(O)(C(C)=O)CC1OC1CC(N)C(O)C(C)O1 STQGQHZAVUOBTE-UHFFFAOYSA-N 0.000 description 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 description 1
- XHVAWZZCDCWGBK-WYRLRVFGSA-M Aurothioglucose Chemical compound OC[C@H]1O[C@H](S[Au])[C@H](O)[C@@H](O)[C@@H]1O XHVAWZZCDCWGBK-WYRLRVFGSA-M 0.000 description 1
- 239000005552 B01AC04 - Clopidogrel Substances 0.000 description 1
- 239000005528 B01AC05 - Ticlopidine Substances 0.000 description 1
- 108010006654 Bleomycin Proteins 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 206010068165 Cardiac valve rupture Diseases 0.000 description 1
- DLGOEMSEDOSKAD-UHFFFAOYSA-N Carmustine Chemical compound ClCCNC(=O)N(N=O)CCCl DLGOEMSEDOSKAD-UHFFFAOYSA-N 0.000 description 1
- 229940123587 Cell cycle inhibitor Drugs 0.000 description 1
- JWBOIMRXGHLCPP-UHFFFAOYSA-N Chloditan Chemical compound C=1C=CC=C(Cl)C=1C(C(Cl)Cl)C1=CC=C(Cl)C=C1 JWBOIMRXGHLCPP-UHFFFAOYSA-N 0.000 description 1
- PTOAARAWEBMLNO-KVQBGUIXSA-N Cladribine Chemical compound C1=NC=2C(N)=NC(Cl)=NC=2N1[C@H]1C[C@H](O)[C@@H](CO)O1 PTOAARAWEBMLNO-KVQBGUIXSA-N 0.000 description 1
- MFYSYFVPBJMHGN-UHFFFAOYSA-N Cortisone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)(O)C(=O)CO)C4C3CCC2=C1 MFYSYFVPBJMHGN-UHFFFAOYSA-N 0.000 description 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 description 1
- 102000016736 Cyclin Human genes 0.000 description 1
- 108050006400 Cyclin Proteins 0.000 description 1
- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 description 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 description 1
- 108010036949 Cyclosporine Proteins 0.000 description 1
- UHDGCWIWMRVCDJ-CCXZUQQUSA-N Cytarabine Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 UHDGCWIWMRVCDJ-CCXZUQQUSA-N 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- GHASVSINZRGABV-UHFFFAOYSA-N Fluorouracil Chemical compound FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 description 1
- 102000009465 Growth Factor Receptors Human genes 0.000 description 1
- 108010009202 Growth Factor Receptors Proteins 0.000 description 1
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 description 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 description 1
- XDXDZDZNSLXDNA-UHFFFAOYSA-N Idarubicin Natural products C1C(N)C(O)C(C)OC1OC1C2=C(O)C(C(=O)C3=CC=CC=C3C3=O)=C3C(O)=C2CC(O)(C(C)=O)C1 XDXDZDZNSLXDNA-UHFFFAOYSA-N 0.000 description 1
- XDXDZDZNSLXDNA-TZNDIEGXSA-N Idarubicin Chemical compound C1[C@H](N)[C@H](O)[C@H](C)O[C@H]1O[C@@H]1C2=C(O)C(C(=O)C3=CC=CC=C3C3=O)=C3C(O)=C2C[C@@](O)(C(C)=O)C1 XDXDZDZNSLXDNA-TZNDIEGXSA-N 0.000 description 1
- 102100022337 Integrin alpha-V Human genes 0.000 description 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 description 1
- FBOZXECLQNJBKD-ZDUSSCGKSA-N L-methotrexate Chemical compound C=1N=C2N=C(N)N=C(N)C2=NC=1CN(C)C1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 FBOZXECLQNJBKD-ZDUSSCGKSA-N 0.000 description 1
- SBDNJUWAMKYJOX-UHFFFAOYSA-N Meclofenamic Acid Chemical compound CC1=CC=C(Cl)C(NC=2C(=CC=CC=2)C(O)=O)=C1Cl SBDNJUWAMKYJOX-UHFFFAOYSA-N 0.000 description 1
- 229930192392 Mitomycin Natural products 0.000 description 1
- NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical compound C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 description 1
- BLXXJMDCKKHMKV-UHFFFAOYSA-N Nabumetone Chemical compound C1=C(CCC(C)=O)C=CC2=CC(OC)=CC=C21 BLXXJMDCKKHMKV-UHFFFAOYSA-N 0.000 description 1
- 239000004687 Nylon copolymer Substances 0.000 description 1
- 229930012538 Paclitaxel Natural products 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
- 229920002367 Polyisobutene Polymers 0.000 description 1
- 108010023197 Streptokinase Proteins 0.000 description 1
- QJJXYPPXXYFBGM-LFZNUXCKSA-N Tacrolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1\C=C(/C)[C@@H]1[C@H](C)[C@@H](O)CC(=O)[C@H](CC=C)/C=C(C)/C[C@H](C)C[C@H](OC)[C@H]([C@H](C[C@H]2C)OC)O[C@@]2(O)C(=O)C(=O)N2CCCC[C@H]2C(=O)O1 QJJXYPPXXYFBGM-LFZNUXCKSA-N 0.000 description 1
- FOCVUCIESVLUNU-UHFFFAOYSA-N Thiotepa Chemical compound C1CN1P(N1CC1)(=S)N1CC1 FOCVUCIESVLUNU-UHFFFAOYSA-N 0.000 description 1
- 229940122388 Thrombin inhibitor Drugs 0.000 description 1
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- 108090000373 Tissue Plasminogen Activator Proteins 0.000 description 1
- 102000003978 Tissue Plasminogen Activator Human genes 0.000 description 1
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 description 1
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 description 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 description 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 description 1
- JXLYSJRDGCGARV-WWYNWVTFSA-N Vinblastine Natural products O=C(O[C@H]1[C@](O)(C(=O)OC)[C@@H]2N(C)c3c(cc(c(OC)c3)[C@]3(C(=O)OC)c4[nH]c5c(c4CCN4C[C@](O)(CC)C[C@H](C3)C4)cccc5)[C@@]32[C@H]2[C@@]1(CC)C=CCN2CC3)C JXLYSJRDGCGARV-WWYNWVTFSA-N 0.000 description 1
- 229940122803 Vinca alkaloid Drugs 0.000 description 1
- 108010048673 Vitronectin Receptors Proteins 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 229960000446 abciximab Drugs 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000001780 adrenocortical effect Effects 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 229940100198 alkylating agent Drugs 0.000 description 1
- 239000002168 alkylating agent Substances 0.000 description 1
- 229960000473 altretamine Drugs 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229960003437 aminoglutethimide Drugs 0.000 description 1
- ROBVIMPUHSLWNV-UHFFFAOYSA-N aminoglutethimide Chemical compound C=1C=C(N)C=CC=1C1(CC)CCC(=O)NC1=O ROBVIMPUHSLWNV-UHFFFAOYSA-N 0.000 description 1
- 239000002333 angiotensin II receptor antagonist Substances 0.000 description 1
- 229940125364 angiotensin receptor blocker Drugs 0.000 description 1
- 229940045799 anthracyclines and related substance Drugs 0.000 description 1
- RWZYAGGXGHYGMB-UHFFFAOYSA-N anthranilic acid Chemical class NC1=CC=CC=C1C(O)=O RWZYAGGXGHYGMB-UHFFFAOYSA-N 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000340 anti-metabolite Effects 0.000 description 1
- 230000000702 anti-platelet effect Effects 0.000 description 1
- 230000000692 anti-sense effect Effects 0.000 description 1
- 230000002965 anti-thrombogenic effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 229940100197 antimetabolite Drugs 0.000 description 1
- 239000002256 antimetabolite Substances 0.000 description 1
- 229940045687 antimetabolites folic acid analogs Drugs 0.000 description 1
- 239000003080 antimitotic agent Substances 0.000 description 1
- 229940045719 antineoplastic alkylating agent nitrosoureas Drugs 0.000 description 1
- 229940045713 antineoplastic alkylating drug ethylene imines Drugs 0.000 description 1
- 210000000709 aorta Anatomy 0.000 description 1
- 210000002376 aorta thoracic Anatomy 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 229960001230 asparagine Drugs 0.000 description 1
- 235000009582 asparagine Nutrition 0.000 description 1
- AUJRCFUBUPVWSZ-XTZHGVARSA-M auranofin Chemical compound CCP(CC)(CC)=[Au]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O AUJRCFUBUPVWSZ-XTZHGVARSA-M 0.000 description 1
- 229960005207 auranofin Drugs 0.000 description 1
- 229960001799 aurothioglucose Drugs 0.000 description 1
- VSRXQHXAPYXROS-UHFFFAOYSA-N azanide;cyclobutane-1,1-dicarboxylic acid;platinum(2+) Chemical compound [NH2-].[NH2-].[Pt+2].OC(=O)C1(C(O)=O)CCC1 VSRXQHXAPYXROS-UHFFFAOYSA-N 0.000 description 1
- 229960002170 azathioprine Drugs 0.000 description 1
- LMEKQMALGUDUQG-UHFFFAOYSA-N azathioprine Chemical compound CN1C=NC([N+]([O-])=O)=C1SC1=NC=NC2=C1NC=N2 LMEKQMALGUDUQG-UHFFFAOYSA-N 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 229960002537 betamethasone Drugs 0.000 description 1
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229960001561 bleomycin Drugs 0.000 description 1
- OYVAGSVQBOHSSS-UAPAGMARSA-O bleomycin A2 Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC=C(N=1)C=1SC=C(N=1)C(=O)NCCC[S+](C)C)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C OYVAGSVQBOHSSS-UAPAGMARSA-O 0.000 description 1
- 229960002092 busulfan Drugs 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 229960004562 carboplatin Drugs 0.000 description 1
- 230000011128 cardiac conduction Effects 0.000 description 1
- 229960005243 carmustine Drugs 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229960004630 chlorambucil Drugs 0.000 description 1
- JCKYGMPEJWAADB-UHFFFAOYSA-N chlorambucil Chemical compound OC(=O)CCCC1=CC=C(N(CCCl)CCCl)C=C1 JCKYGMPEJWAADB-UHFFFAOYSA-N 0.000 description 1
- 229960001265 ciclosporin Drugs 0.000 description 1
- 229960004316 cisplatin Drugs 0.000 description 1
- DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 description 1
- 229960003009 clopidogrel Drugs 0.000 description 1
- GKTWGGQPFAXNFI-HNNXBMFYSA-N clopidogrel Chemical compound C1([C@H](N2CC=3C=CSC=3CC2)C(=O)OC)=CC=CC=C1Cl GKTWGGQPFAXNFI-HNNXBMFYSA-N 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 229960004544 cortisone Drugs 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 229940043378 cyclin-dependent kinase inhibitor Drugs 0.000 description 1
- 229960004397 cyclophosphamide Drugs 0.000 description 1
- 229930182912 cyclosporin Natural products 0.000 description 1
- 229960000684 cytarabine Drugs 0.000 description 1
- 229960000975 daunorubicin Drugs 0.000 description 1
- STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- CFCUWKMKBJTWLW-UHFFFAOYSA-N deoliosyl-3C-alpha-L-digitoxosyl-MTM Natural products CC=1C(O)=C2C(O)=C3C(=O)C(OC4OC(C)C(O)C(OC5OC(C)C(O)C(OC6OC(C)C(O)C(C)(O)C6)C5)C4)C(C(OC)C(=O)C(O)C(C)O)CC3=CC2=CC=1OC(OC(C)C1O)CC1OC1CC(O)C(O)C(C)O1 CFCUWKMKBJTWLW-UHFFFAOYSA-N 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 229960003957 dexamethasone Drugs 0.000 description 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 1
- 229960001259 diclofenac Drugs 0.000 description 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 description 1
- 238000003618 dip coating Methods 0.000 description 1
- 229960002768 dipyridamole Drugs 0.000 description 1
- IZEKFCXSFNUWAM-UHFFFAOYSA-N dipyridamole Chemical compound C=12N=C(N(CCO)CCO)N=C(N3CCCCC3)C2=NC(N(CCO)CCO)=NC=1N1CCCCC1 IZEKFCXSFNUWAM-UHFFFAOYSA-N 0.000 description 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 229960004679 doxorubicin Drugs 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000003511 endothelial effect Effects 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 229940011871 estrogen Drugs 0.000 description 1
- 239000000262 estrogen Substances 0.000 description 1
- VJJPUSNTGOMMGY-MRVIYFEKSA-N etoposide Chemical compound COC1=C(O)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H]4O[C@H](C)OC[C@H]4O3)O)[C@@H]3[C@@H]2C(OC3)=O)=C1 VJJPUSNTGOMMGY-MRVIYFEKSA-N 0.000 description 1
- 229960005420 etoposide Drugs 0.000 description 1
- 239000003527 fibrinolytic agent Substances 0.000 description 1
- 229960000961 floxuridine Drugs 0.000 description 1
- ODKNJVUHOIMIIZ-RRKCRQDMSA-N floxuridine Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(F)=C1 ODKNJVUHOIMIIZ-RRKCRQDMSA-N 0.000 description 1
- 229960002011 fludrocortisone Drugs 0.000 description 1
- AAXVEMMRQDVLJB-BULBTXNYSA-N fludrocortisone Chemical compound O=C1CC[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 AAXVEMMRQDVLJB-BULBTXNYSA-N 0.000 description 1
- 229960002949 fluorouracil Drugs 0.000 description 1
- 150000002224 folic acids Chemical class 0.000 description 1
- 229940015045 gold sodium thiomalate Drugs 0.000 description 1
- 238000009998 heat setting Methods 0.000 description 1
- UUVWYPNAQBNQJQ-UHFFFAOYSA-N hexamethylmelamine Chemical compound CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1 UUVWYPNAQBNQJQ-UHFFFAOYSA-N 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 229960000890 hydrocortisone Drugs 0.000 description 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 description 1
- 229960001680 ibuprofen Drugs 0.000 description 1
- 229960000908 idarubicin Drugs 0.000 description 1
- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 description 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 description 1
- 229960000905 indomethacin Drugs 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000011256 inorganic filler Substances 0.000 description 1
- 229910003475 inorganic filler Inorganic materials 0.000 description 1
- 229960004752 ketorolac Drugs 0.000 description 1
- OZWKMVRBQXNZKK-UHFFFAOYSA-N ketorolac Chemical compound OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 OZWKMVRBQXNZKK-UHFFFAOYSA-N 0.000 description 1
- 229940043355 kinase inhibitor Drugs 0.000 description 1
- 210000005240 left ventricle Anatomy 0.000 description 1
- 229940124302 mTOR inhibitor Drugs 0.000 description 1
- 239000003628 mammalian target of rapamycin inhibitor Substances 0.000 description 1
- 229960004961 mechlorethamine Drugs 0.000 description 1
- HAWPXGHAZFHHAD-UHFFFAOYSA-N mechlorethamine Chemical compound ClCCN(C)CCCl HAWPXGHAZFHHAD-UHFFFAOYSA-N 0.000 description 1
- 229960003803 meclofenamic acid Drugs 0.000 description 1
- 229960003464 mefenamic acid Drugs 0.000 description 1
- HYYBABOKPJLUIN-UHFFFAOYSA-N mefenamic acid Chemical compound CC1=CC=CC(NC=2C(=CC=CC=2)C(O)=O)=C1C HYYBABOKPJLUIN-UHFFFAOYSA-N 0.000 description 1
- 229960001924 melphalan Drugs 0.000 description 1
- SGDBTWWWUNNDEQ-LBPRGKRZSA-N melphalan Chemical compound OC(=O)[C@@H](N)CC1=CC=C(N(CCCl)CCCl)C=C1 SGDBTWWWUNNDEQ-LBPRGKRZSA-N 0.000 description 1
- 229960001428 mercaptopurine Drugs 0.000 description 1
- GLVAUDGFNGKCSF-UHFFFAOYSA-N mercaptopurine Chemical compound S=C1NC=NC2=C1NC=N2 GLVAUDGFNGKCSF-UHFFFAOYSA-N 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 229960000485 methotrexate Drugs 0.000 description 1
- HPNSFSBZBAHARI-UHFFFAOYSA-N micophenolic acid Natural products OC1=C(CC=C(C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-UHFFFAOYSA-N 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 229960004857 mitomycin Drugs 0.000 description 1
- 229960000350 mitotane Drugs 0.000 description 1
- 229960001156 mitoxantrone Drugs 0.000 description 1
- KKZJGLLVHKMTCM-UHFFFAOYSA-N mitoxantrone Chemical compound O=C1C2=C(O)C=CC(O)=C2C(=O)C2=C1C(NCCNCCO)=CC=C2NCCNCCO KKZJGLLVHKMTCM-UHFFFAOYSA-N 0.000 description 1
- 229940014456 mycophenolate Drugs 0.000 description 1
- HPNSFSBZBAHARI-RUDMXATFSA-N mycophenolic acid Chemical compound OC1=C(C\C=C(/C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-RUDMXATFSA-N 0.000 description 1
- 229960004270 nabumetone Drugs 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 description 1
- 229960001592 paclitaxel Drugs 0.000 description 1
- 229960002340 pentostatin Drugs 0.000 description 1
- FPVKHBSQESCIEP-JQCXWYLXSA-N pentostatin Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(N=CNC[C@H]2O)=C2N=C1 FPVKHBSQESCIEP-JQCXWYLXSA-N 0.000 description 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229960002895 phenylbutazone Drugs 0.000 description 1
- VYMDGNCVAMGZFE-UHFFFAOYSA-N phenylbutazonum Chemical compound O=C1C(CCCC)C(=O)N(C=2C=CC=CC=2)N1C1=CC=CC=C1 VYMDGNCVAMGZFE-UHFFFAOYSA-N 0.000 description 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- 230000000379 polymerizing effect Effects 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229960005205 prednisolone Drugs 0.000 description 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 1
- 229960004618 prednisone Drugs 0.000 description 1
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 229960000624 procarbazine Drugs 0.000 description 1
- CPTBDICYNRMXFX-UHFFFAOYSA-N procarbazine Chemical compound CNNCC1=CC=C(C(=O)NC(C)C)C=C1 CPTBDICYNRMXFX-UHFFFAOYSA-N 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 150000003212 purines Chemical class 0.000 description 1
- 150000003230 pyrimidines Chemical class 0.000 description 1
- 239000002464 receptor antagonist Substances 0.000 description 1
- 229940044551 receptor antagonist Drugs 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical class OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 1
- 238000004626 scanning electron microscopy Methods 0.000 description 1
- 239000012781 shape memory material Substances 0.000 description 1
- 230000019491 signal transduction Effects 0.000 description 1
- AGHLUVOCTHWMJV-UHFFFAOYSA-J sodium;gold(3+);2-sulfanylbutanedioate Chemical compound [Na+].[Au+3].[O-]C(=O)CC(S)C([O-])=O.[O-]C(=O)CC(S)C([O-])=O AGHLUVOCTHWMJV-UHFFFAOYSA-J 0.000 description 1
- 230000003637 steroidlike Effects 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 229960005202 streptokinase Drugs 0.000 description 1
- 229960000894 sulindac Drugs 0.000 description 1
- MLKXDPUZXIRXEP-MFOYZWKCSA-N sulindac Chemical compound CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(S(C)=O)C=C1 MLKXDPUZXIRXEP-MFOYZWKCSA-N 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 1
- NRUKOCRGYNPUPR-QBPJDGROSA-N teniposide Chemical compound COC1=C(O)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H]4O[C@@H](OC[C@H]4O3)C=3SC=CC=3)O)[C@@H]3[C@@H]2C(OC3)=O)=C1 NRUKOCRGYNPUPR-QBPJDGROSA-N 0.000 description 1
- 229960001278 teniposide Drugs 0.000 description 1
- 238000009864 tensile test Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 229960001196 thiotepa Drugs 0.000 description 1
- 239000003868 thrombin inhibitor Substances 0.000 description 1
- 229960005001 ticlopidine Drugs 0.000 description 1
- PHWBOXQYWZNQIN-UHFFFAOYSA-N ticlopidine Chemical compound ClC1=CC=CC=C1CN1CC(C=CS2)=C2CC1 PHWBOXQYWZNQIN-UHFFFAOYSA-N 0.000 description 1
- 229960003087 tioguanine Drugs 0.000 description 1
- 229960000187 tissue plasminogen activator Drugs 0.000 description 1
- 229960001017 tolmetin Drugs 0.000 description 1
- UPSPUYADGBWSHF-UHFFFAOYSA-N tolmetin Chemical compound C1=CC(C)=CC=C1C(=O)C1=CC=C(CC(O)=O)N1C UPSPUYADGBWSHF-UHFFFAOYSA-N 0.000 description 1
- 229960005294 triamcinolone Drugs 0.000 description 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 1
- 150000003673 urethanes Chemical class 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 229960003048 vinblastine Drugs 0.000 description 1
- JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 description 1
- 229960004528 vincristine Drugs 0.000 description 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
- GBABOYUKABKIAF-GHYRFKGUSA-N vinorelbine Chemical compound C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC GBABOYUKABKIAF-GHYRFKGUSA-N 0.000 description 1
- 229960002066 vinorelbine Drugs 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2415—Manufacturing methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2403—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with pivoting rigid closure members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/243—Deployment by mechanical expansion
- A61F2/2433—Deployment by mechanical expansion using balloon catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C70/00—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts
- B29C70/68—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts by incorporating or moulding on preformed parts, e.g. inserts or layers, e.g. foam blocks
- B29C70/681—Component parts, details or accessories; Auxiliary operations
- B29C70/683—Pretreatment of the preformed part, e.g. insert
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
- A61F2002/9583—Means for holding the stent on the balloon, e.g. using protrusions, adhesives or an outer sleeve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0076—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/16—Materials with shape-memory or superelastic properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C53/00—Shaping by bending, folding, twisting, straightening or flattening; Apparatus therefor
- B29C53/36—Bending and joining, e.g. for making hollow articles
- B29C53/38—Bending and joining, e.g. for making hollow articles by bending sheets or strips at right angles to the longitudinal axis of the article being formed and joining the edges
- B29C53/40—Bending and joining, e.g. for making hollow articles by bending sheets or strips at right angles to the longitudinal axis of the article being formed and joining the edges for articles of definite length, i.e. discrete articles
- B29C53/42—Bending and joining, e.g. for making hollow articles by bending sheets or strips at right angles to the longitudinal axis of the article being formed and joining the edges for articles of definite length, i.e. discrete articles using internal forming surfaces, e.g. mandrels
- B29C53/44—Bending and joining, e.g. for making hollow articles by bending sheets or strips at right angles to the longitudinal axis of the article being formed and joining the edges for articles of definite length, i.e. discrete articles using internal forming surfaces, e.g. mandrels rotatable about the axis of the article
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D23/00—Producing tubular articles
- B29D23/001—Pipes; Pipe joints
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49405—Valve or choke making
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Mechanical Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Composite Materials (AREA)
- Prostheses (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261675744P | 2012-07-25 | 2012-07-25 | |
| US13/797,633 US9283072B2 (en) | 2012-07-25 | 2013-03-12 | Everting transcatheter valve and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2823223T3 true ES2823223T3 (es) | 2021-05-06 |
Family
ID=49995594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18204192T Active ES2823223T3 (es) | 2012-07-25 | 2013-06-18 | Válvula transcatéter de eversión |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US9283072B2 (https=) |
| EP (5) | EP3501454B1 (https=) |
| JP (5) | JP6382808B2 (https=) |
| KR (2) | KR102151603B1 (https=) |
| CN (3) | CN106726007B (https=) |
| AU (3) | AU2013293455B2 (https=) |
| BR (1) | BR112015001626A2 (https=) |
| CA (5) | CA3098032C (https=) |
| ES (1) | ES2823223T3 (https=) |
| RU (1) | RU2015106127A (https=) |
| WO (1) | WO2014018189A2 (https=) |
Families Citing this family (104)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
| US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
| US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| WO2013019756A2 (en) | 2011-07-29 | 2013-02-07 | Carnegie Mellon University | Artificial valved conduits for cardiac reconstructive procedures and methods for their production |
| US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
| US9283072B2 (en) | 2012-07-25 | 2016-03-15 | W. L. Gore & Associates, Inc. | Everting transcatheter valve and methods |
| US10376360B2 (en) | 2012-07-27 | 2019-08-13 | W. L. Gore & Associates, Inc. | Multi-frame prosthetic valve apparatus and methods |
| US10966820B2 (en) | 2012-12-19 | 2021-04-06 | W. L. Gore & Associates, Inc. | Geometric control of bending character in prosthetic heart valve leaflets |
| US9101469B2 (en) | 2012-12-19 | 2015-08-11 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with leaflet shelving |
| US9737398B2 (en) | 2012-12-19 | 2017-08-22 | W. L. Gore & Associates, Inc. | Prosthetic valves, frames and leaflets and methods thereof |
| US9968443B2 (en) | 2012-12-19 | 2018-05-15 | W. L. Gore & Associates, Inc. | Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet |
| US9144492B2 (en) | 2012-12-19 | 2015-09-29 | W. L. Gore & Associates, Inc. | Truncated leaflet for prosthetic heart valves, preformed valve |
| US10039638B2 (en) | 2012-12-19 | 2018-08-07 | W. L. Gore & Associates, Inc. | Geometric prosthetic heart valves |
| US10321986B2 (en) * | 2012-12-19 | 2019-06-18 | W. L. Gore & Associates, Inc. | Multi-frame prosthetic heart valve |
| CA2904715C (en) * | 2013-03-08 | 2022-07-26 | Carnegie Mellon University | Expandable implantable fluoropolymer conduit |
| US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
| US11076952B2 (en) * | 2013-06-14 | 2021-08-03 | The Regents Of The University Of California | Collapsible atrioventricular valve prosthesis |
| WO2015120122A2 (en) | 2014-02-05 | 2015-08-13 | Robert Vidlund | Apparatus and methods for transfemoral delivery of prosthetic mitral valve |
| WO2016112085A2 (en) * | 2015-01-07 | 2016-07-14 | Mark Christianson | Prosthetic mitral valves and apparatus and methods for delivery of same |
| EP3174502B1 (en) | 2014-07-30 | 2022-04-06 | Cardiovalve Ltd | Apparatus for implantation of an articulatable prosthetic valve |
| CN106659567B (zh) | 2014-08-18 | 2019-06-14 | W.L.戈尔及同仁股份有限公司 | 带有用于假体瓣膜的一体缝合封套的框架 |
| US9827094B2 (en) | 2014-09-15 | 2017-11-28 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with retention elements |
| CA2975294A1 (en) | 2015-02-05 | 2016-08-11 | Tendyne Holdings, Inc. | Expandable epicardial pads and devices and methods for delivery of same |
| US10232564B2 (en) * | 2015-04-29 | 2019-03-19 | Edwards Lifesciences Corporation | Laminated sealing member for prosthetic heart valve |
| US10631984B2 (en) | 2015-12-15 | 2020-04-28 | Neovasc Tiara Inc. | Transseptal delivery system |
| EP4183372A1 (en) | 2016-01-29 | 2023-05-24 | Neovasc Tiara Inc. | Prosthetic valve for avoiding obstruction of outflow |
| WO2017151900A1 (en) | 2016-03-02 | 2017-09-08 | Peca Labs, Inc. | Expandable implantable conduit |
| US10201416B2 (en) | 2016-05-16 | 2019-02-12 | Boston Scientific Scimed, Inc. | Replacement heart valve implant with invertible leaflets |
| US10350062B2 (en) * | 2016-07-21 | 2019-07-16 | Edwards Lifesciences Corporation | Replacement heart valve prosthesis |
| US10631979B2 (en) | 2016-10-10 | 2020-04-28 | Peca Labs, Inc. | Transcatheter stent and valve assembly |
| EP3541462A4 (en) | 2016-11-21 | 2020-06-17 | Neovasc Tiara Inc. | METHODS AND SYSTEMS FOR THE QUICK RETURN OF A TRANSCATHETER HEART VALVE RELEASE SYSTEM |
| US10653523B2 (en) | 2017-01-19 | 2020-05-19 | 4C Medical Technologies, Inc. | Systems, methods and devices for delivery systems, methods and devices for implanting prosthetic heart valves |
| US10561495B2 (en) | 2017-01-24 | 2020-02-18 | 4C Medical Technologies, Inc. | Systems, methods and devices for two-step delivery and implantation of prosthetic heart valve |
| US12029647B2 (en) * | 2017-03-07 | 2024-07-09 | 4C Medical Technologies, Inc. | Systems, methods and devices for prosthetic heart valve with single valve leaflet |
| US12036113B2 (en) | 2017-06-14 | 2024-07-16 | 4C Medical Technologies, Inc. | Delivery of heart chamber prosthetic valve implant |
| US12458491B2 (en) * | 2017-06-30 | 2025-11-04 | Ohio State Innovation Foundation | Methods to improve the durability of polymeric heart valves |
| WO2019028264A1 (en) | 2017-08-03 | 2019-02-07 | The Regents Of The University Of California | AURICULAR CAGE FOR THE PLACEMENT, FASTENING AND ANCHORING OF ATRIOVENTRICULAR VALVES |
| CN111263622A (zh) | 2017-08-25 | 2020-06-09 | 内奥瓦斯克迪亚拉公司 | 顺序展开的经导管二尖瓣假体 |
| CN111182856B (zh) | 2017-09-12 | 2022-04-29 | W.L.戈尔及同仁股份有限公司 | 用于假体瓣膜的瓣叶框架附连件 |
| CN111163728B (zh) | 2017-09-27 | 2022-04-29 | W.L.戈尔及同仁股份有限公司 | 具有机械联接的瓣叶的假体瓣膜 |
| CN111132636B (zh) | 2017-09-27 | 2022-04-08 | W.L.戈尔及同仁股份有限公司 | 带有可扩张框架的假体瓣膜以及相关系统和方法 |
| US11090153B2 (en) * | 2017-10-13 | 2021-08-17 | W. L. Gore & Associates, Inc. | Telescoping prosthetic valve and delivery system |
| KR102609690B1 (ko) | 2017-10-19 | 2023-12-05 | 안테리스 테크놀로지스 코퍼레이션 | 감소된 봉합을 갖는 교체용 심장 판막 |
| US11439502B2 (en) | 2017-10-31 | 2022-09-13 | W. L. Gore & Associates, Inc. | Medical valve and leaflet promoting tissue ingrowth |
| EP3703615B1 (en) | 2017-10-31 | 2024-05-15 | W. L. Gore & Associates, Inc. | Transcatheter deployment systems and associated methods |
| US11154397B2 (en) | 2017-10-31 | 2021-10-26 | W. L. Gore & Associates, Inc. | Jacket for surgical heart valve |
| US11123183B2 (en) | 2017-10-31 | 2021-09-21 | W. L. Gore & Associates, Inc. | Prosthetic heart valve |
| CN111315419A (zh) * | 2017-10-31 | 2020-06-19 | W.L.戈尔及同仁股份有限公司 | 合成假体瓣膜瓣叶 |
| WO2019195860A2 (en) | 2018-04-04 | 2019-10-10 | Vdyne, Llc | Devices and methods for anchoring transcatheter heart valve |
| CN112087972B (zh) * | 2018-05-08 | 2024-10-29 | W.L.戈尔及同仁股份有限公司 | 阻塞设备 |
| AU2019269741B2 (en) * | 2018-05-18 | 2023-04-27 | Anteris Technologies Corporation | Replacement heart valve assembly with a valve loaded distally from a stent |
| US11666439B2 (en) | 2018-05-18 | 2023-06-06 | Anteris Technologies Corporation | Inverted heart valve for transcatheter valve replacement |
| CN112203617A (zh) | 2018-05-18 | 2021-01-08 | 安特瑞斯技术公司 | 具有收拢密封区域的心脏瓣膜 |
| PL238191B1 (pl) * | 2018-07-24 | 2021-07-19 | American Heart Of Poland Spolka Akcyjna | Niskoprofilowa, rozprężana na balonie sztuczna zastawka serca, zwłaszcza aortalna, implantowana przezskórnie |
| US11857441B2 (en) | 2018-09-04 | 2024-01-02 | 4C Medical Technologies, Inc. | Stent loading device |
| US10321995B1 (en) | 2018-09-20 | 2019-06-18 | Vdyne, Llc | Orthogonally delivered transcatheter heart valve replacement |
| US11344413B2 (en) | 2018-09-20 | 2022-05-31 | Vdyne, Inc. | Transcatheter deliverable prosthetic heart valves and methods of delivery |
| US12186187B2 (en) | 2018-09-20 | 2025-01-07 | Vdyne, Inc. | Transcatheter deliverable prosthetic heart valves and methods of delivery |
| US11278437B2 (en) | 2018-12-08 | 2022-03-22 | Vdyne, Inc. | Compression capable annular frames for side delivery of transcatheter heart valve replacement |
| US12310850B2 (en) | 2018-09-20 | 2025-05-27 | Vdyne, Inc. | Transcatheter deliverable prosthetic heart valves and methods of delivery |
| US11071627B2 (en) | 2018-10-18 | 2021-07-27 | Vdyne, Inc. | Orthogonally delivered transcatheter heart valve frame for valve in valve prosthesis |
| US10595994B1 (en) | 2018-09-20 | 2020-03-24 | Vdyne, Llc | Side-delivered transcatheter heart valve replacement |
| US11109969B2 (en) | 2018-10-22 | 2021-09-07 | Vdyne, Inc. | Guidewire delivery of transcatheter heart valve |
| USD926322S1 (en) | 2018-11-07 | 2021-07-27 | W. L. Gore & Associates, Inc. | Heart valve cover |
| EP3876870B1 (en) | 2018-11-08 | 2023-12-20 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
| US11253359B2 (en) | 2018-12-20 | 2022-02-22 | Vdyne, Inc. | Proximal tab for side-delivered transcatheter heart valves and methods of delivery |
| WO2020146842A1 (en) | 2019-01-10 | 2020-07-16 | Vdyne, Llc | Anchor hook for side-delivery transcatheter heart valve prosthesis |
| US11185409B2 (en) | 2019-01-26 | 2021-11-30 | Vdyne, Inc. | Collapsible inner flow control component for side-delivered transcatheter heart valve prosthesis |
| US11273032B2 (en) * | 2019-01-26 | 2022-03-15 | Vdyne, Inc. | Collapsible inner flow control component for side-deliverable transcatheter heart valve prosthesis |
| US12544226B2 (en) | 2019-02-14 | 2026-02-10 | 4C Medical Technologies, Inc. | Hydrophilic skirt for paravalvular leak mitigation and fit and apposition optimization for prosthetic heart valve implants |
| US11497601B2 (en) | 2019-03-01 | 2022-11-15 | W. L. Gore & Associates, Inc. | Telescoping prosthetic valve with retention element |
| EP4729034A2 (en) | 2019-03-05 | 2026-04-22 | VDyne, Inc. | Tricuspid regurgitation control devices for orthogonal transcatheter heart valve prosthesis |
| AU2020233892A1 (en) | 2019-03-08 | 2021-11-04 | Neovasc Tiara Inc. | Retrievable prosthesis delivery system |
| US11173027B2 (en) | 2019-03-14 | 2021-11-16 | Vdyne, Inc. | Side-deliverable transcatheter prosthetic valves and methods for delivering and anchoring the same |
| US11076956B2 (en) | 2019-03-14 | 2021-08-03 | Vdyne, Inc. | Proximal, distal, and anterior anchoring tabs for side-delivered transcatheter mitral valve prosthesis |
| US11602429B2 (en) | 2019-04-01 | 2023-03-14 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
| WO2020210652A1 (en) | 2019-04-10 | 2020-10-15 | Neovasc Tiara Inc. | Prosthetic valve with natural blood flow |
| JP7381601B2 (ja) | 2019-04-12 | 2023-11-15 | エドワーズ ライフサイエンシーズ コーポレイション | マルチパートフレーム及び関連するレジリエントブリッジ特徴部を備えた弁 |
| US11452628B2 (en) | 2019-04-15 | 2022-09-27 | 4C Medical Technologies, Inc. | Loading systems for collapsible prosthetic heart valve devices and methods thereof |
| CN114072106B (zh) | 2019-05-04 | 2025-09-19 | 维迪内股份有限公司 | 用于在自体瓣环中部署侧面递送的假体心脏瓣膜的束紧装置和方法 |
| US11779742B2 (en) | 2019-05-20 | 2023-10-10 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
| EP3975936A4 (en) | 2019-05-28 | 2022-08-03 | Regents of the University of Minnesota | ENGINEERING VALVE AND METHOD OF MANUFACTURE |
| US11311376B2 (en) | 2019-06-20 | 2022-04-26 | Neovase Tiara Inc. | Low profile prosthetic mitral valve |
| CA3143781C (en) * | 2019-08-08 | 2024-06-18 | Kyle W Colavito | Prosthetic valve with asymmetric leaflets |
| CN121101808A (zh) | 2019-08-20 | 2025-12-12 | 维迪内股份有限公司 | 用于可侧面递送经导管人工瓣膜的递送和取回装置和方法 |
| EP4021445B8 (en) | 2019-08-26 | 2025-12-10 | VDyne, Inc. | Side-deliverable transcatheter prosthetic valves |
| US11234813B2 (en) | 2020-01-17 | 2022-02-01 | Vdyne, Inc. | Ventricular stability elements for side-deliverable prosthetic heart valves and methods of delivery |
| US12133797B2 (en) | 2020-01-31 | 2024-11-05 | 4C Medical Technologies, Inc. | Prosthetic heart valve delivery system: paddle attachment feature |
| US11931253B2 (en) | 2020-01-31 | 2024-03-19 | 4C Medical Technologies, Inc. | Prosthetic heart valve delivery system: ball-slide attachment |
| EP3875060A1 (en) * | 2020-03-02 | 2021-09-08 | Biotronik AG | Heart valve prosthesis |
| US12053375B2 (en) | 2020-03-05 | 2024-08-06 | 4C Medical Technologies, Inc. | Prosthetic mitral valve with improved atrial and/or annular apposition and paravalvular leakage mitigation |
| US11992403B2 (en) | 2020-03-06 | 2024-05-28 | 4C Medical Technologies, Inc. | Devices, systems and methods for improving recapture of prosthetic heart valve device with stent frame having valve support with inwardly stent cells |
| CN114258294A (zh) * | 2020-04-03 | 2022-03-29 | 爱德华兹生命科学公司 | 用于假体心脏瓣膜的多层覆盖物 |
| US20230248513A1 (en) | 2020-07-07 | 2023-08-10 | Anteris Technologies Corporation | Expandable frame for improved hemodynamic performance of transcatheter replacement heart valve |
| WO2022039853A1 (en) | 2020-08-19 | 2022-02-24 | Tendyne Holdings, Inc. | Fully-transseptal apical pad with pulley for tensioning |
| EP4552613A3 (en) * | 2020-10-06 | 2025-07-30 | Edwards Lifesciences Corporation | Protective covers for prosthetic valves |
| US11197755B1 (en) * | 2020-10-28 | 2021-12-14 | Occam Labs LLC | Systems, devices and methods for folded unibody heart valve stents |
| US11246726B1 (en) | 2021-02-10 | 2022-02-15 | Occam Labs LLC | Systems, devices and methods for delivery systems |
| US12594164B1 (en) | 2022-09-01 | 2026-04-07 | 4C Medical Technologies, Inc. | Prosthetic heart valve for natural blood flow |
| US11622853B1 (en) | 2022-09-30 | 2023-04-11 | Anteris Technologies Corporation | Prosthetic heart valves |
| JP2025534210A (ja) | 2022-10-14 | 2025-10-15 | ブイダイン,インコーポレイテッド | 弁輪上支持体を使用して人工心臓弁を送達するデバイス及び方法 |
| US20240366366A1 (en) | 2023-03-24 | 2024-11-07 | 4C Medical Technologies, Inc. | Implant delivery |
| CN118680727B (zh) * | 2024-06-20 | 2025-09-16 | 上海以心医疗器械有限公司 | 外科手术用瓣架及瓣膜假体 |
| WO2026044101A2 (en) * | 2024-08-23 | 2026-02-26 | Edwards Lifesciences Corporation | Prosthetic heart valve |
Family Cites Families (492)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US654799A (en) | 1900-03-08 | 1900-07-31 | Morris H Levett | Display device. |
| SE392582B (sv) | 1970-05-21 | 1977-04-04 | Gore & Ass | Forfarande vid framstellning av ett porost material, genom expandering och streckning av en tetrafluoretenpolymer framstelld i ett pastabildande strengsprutningsforfarande |
| US3739402A (en) | 1970-10-15 | 1973-06-19 | Cutter Lab | Bicuspid fascia lata valve |
| US4340091A (en) | 1975-05-07 | 1982-07-20 | Albany International Corp. | Elastomeric sheet materials for heart valve and other prosthetic implants |
| US4178639A (en) | 1978-04-06 | 1979-12-18 | Carbomedics, Inc. | Two-leaflet heart valve |
| DE2947743C2 (de) | 1978-11-30 | 1983-12-08 | Sumitomo Electric Industries, Ltd., Osaka | Einheitliches, poröses röhrenförmiges Gebilde aus Polytetrafluoräthylen |
| US4265694A (en) | 1978-12-14 | 1981-05-05 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Method of making unitized three leaflet heart valve |
| US4222126A (en) | 1978-12-14 | 1980-09-16 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare | Unitized three leaflet heart valve |
| US4477930A (en) | 1982-09-28 | 1984-10-23 | Mitral Medical International, Inc. | Natural tissue heat valve and method of making same |
| CA1232407A (en) | 1983-06-23 | 1988-02-09 | David K. Walker | Bubble heart valve |
| US4556996A (en) | 1983-08-04 | 1985-12-10 | Robert S. Wallace | Heart valve |
| US4626255A (en) | 1983-09-23 | 1986-12-02 | Christian Weinhold | Heart valve bioprothesis |
| FR2591100B1 (fr) | 1985-12-09 | 1990-08-17 | Clinique Residence Parc | Prothese valvulaire tricuspide. |
| US5071609A (en) | 1986-11-26 | 1991-12-10 | Baxter International Inc. | Process of manufacturing porous multi-expanded fluoropolymers |
| US4816339A (en) | 1987-04-28 | 1989-03-28 | Baxter International Inc. | Multi-layered poly(tetrafluoroethylene)/elastomer materials useful for in vivo implantation |
| US4851000A (en) | 1987-07-31 | 1989-07-25 | Pacific Biomedical Holdings, Ltd. | Bioprosthetic valve stent |
| US4877661A (en) | 1987-10-19 | 1989-10-31 | W. L. Gore & Associates, Inc. | Rapidly recoverable PTFE and process therefore |
| DE3879613T2 (de) | 1987-10-19 | 1993-10-07 | Gore & Ass | Schnellrückstellbares PTFE und Verfahren zu dessen Herstellung. |
| US5026513A (en) | 1987-10-19 | 1991-06-25 | W. L. Gore & Associates, Inc. | Process for making rapidly recoverable PTFE |
| FR2642960B1 (fr) | 1989-02-15 | 1994-02-25 | Dassault Breguet Aviation | Valve cardiaque prothetique |
| US4955899A (en) | 1989-05-26 | 1990-09-11 | Impra, Inc. | Longitudinally compliant vascular graft |
| GB9012716D0 (en) | 1990-06-07 | 1990-08-01 | Frater Robert W M | Mitral heart valve replacements |
| US5064435A (en) | 1990-06-28 | 1991-11-12 | Schneider (Usa) Inc. | Self-expanding prosthesis having stable axial length |
| US5163955A (en) | 1991-01-24 | 1992-11-17 | Autogenics | Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment |
| US6128068A (en) | 1991-02-22 | 2000-10-03 | Canon Kabushiki Kaisha | Projection exposure apparatus including an illumination optical system that forms a secondary light source with a particular intensity distribution |
| US5489297A (en) | 1992-01-27 | 1996-02-06 | Duran; Carlos M. G. | Bioprosthetic heart valve with absorbable stent |
| US5258023A (en) | 1992-02-12 | 1993-11-02 | Reger Medical Development, Inc. | Prosthetic heart valve |
| US5405378A (en) | 1992-05-20 | 1995-04-11 | Strecker; Ernst P. | Device with a prosthesis implantable in the body of a patient |
| US5342305A (en) | 1992-08-13 | 1994-08-30 | Cordis Corporation | Variable distention angioplasty balloon assembly |
| US5628782A (en) | 1992-12-11 | 1997-05-13 | W. L. Gore & Associates, Inc. | Method of making a prosthetic vascular graft |
| US5772884A (en) | 1993-01-25 | 1998-06-30 | Daikin Industries, Ltd. | Porous polytetrafluoroethylene film and process for preparation thereof |
| CA2169549C (en) | 1993-08-18 | 2000-07-11 | James D. Lewis | A tubular intraluminal graft |
| US6027779A (en) | 1993-08-18 | 2000-02-22 | W. L. Gore & Associates, Inc. | Thin-wall polytetrafluoroethylene tube |
| WO1995009586A1 (en) | 1993-10-01 | 1995-04-13 | Emory University | Self-expanding intraluminal composite prosthesis |
| IT1269443B (it) | 1994-01-19 | 1997-04-01 | Stefano Nazari | Protesi vascolare per la sostituzione o il rivestimento interno di vasi sanguigni di medio e grande diametro e dispositivo per la sua applicazione senza interruzione del flusso ematico |
| US5549663A (en) | 1994-03-09 | 1996-08-27 | Cordis Corporation | Endoprosthesis having graft member and exposed welded end junctions, method and procedure |
| CA2189662C (en) | 1994-05-06 | 2004-12-14 | William M. Colone | Radially expandable polytetrafluoroethylene |
| US6013854A (en) | 1994-06-17 | 2000-01-11 | Terumo Kabushiki Kaisha | Indwelling stent and the method for manufacturing the same |
| US5554185A (en) | 1994-07-18 | 1996-09-10 | Block; Peter C. | Inflatable prosthetic cardiovascular valve for percutaneous transluminal implantation of same |
| AU688404B2 (en) | 1994-09-02 | 1998-03-12 | W.L. Gore & Associates, Inc. | Porous polytetrafluoroethylene compositions |
| JPH10505266A (ja) | 1994-09-02 | 1998-05-26 | ダブリュ.エル.ゴア アンド アソシエイツ,インコーポレイティド | 非対称の多孔質ポリテトラフルオロエチレン成形体とその製造方法 |
| US5562729A (en) | 1994-11-01 | 1996-10-08 | Biocontrol Technology, Inc. | Heart valve |
| CA2301351C (en) | 1994-11-28 | 2002-01-22 | Advanced Cardiovascular Systems, Inc. | Method and apparatus for direct laser cutting of metal stents |
| US6896696B2 (en) | 1998-11-20 | 2005-05-24 | Scimed Life Systems, Inc. | Flexible and expandable stent |
| US6451047B2 (en) | 1995-03-10 | 2002-09-17 | Impra, Inc. | Encapsulated intraluminal stent-graft and methods of making same |
| US5476589A (en) | 1995-03-10 | 1995-12-19 | W. L. Gore & Associates, Inc. | Porpous PTFE film and a manufacturing method therefor |
| US5534007A (en) | 1995-05-18 | 1996-07-09 | Scimed Life Systems, Inc. | Stent deployment catheter with collapsible sheath |
| US5766201A (en) | 1995-06-07 | 1998-06-16 | Boston Scientific Corporation | Expandable catheter |
| US5814405A (en) | 1995-08-04 | 1998-09-29 | W. L. Gore & Associates, Inc. | Strong, air permeable membranes of polytetrafluoroethylene |
| US20060271091A1 (en) | 1995-09-18 | 2006-11-30 | Campbell Carey V | Balloon catheter device |
| US5868704A (en) | 1995-09-18 | 1999-02-09 | W. L. Gore & Associates, Inc. | Balloon catheter device |
| US5752934A (en) | 1995-09-18 | 1998-05-19 | W. L. Gore & Associates, Inc. | Balloon catheter device |
| US5824037A (en) | 1995-10-03 | 1998-10-20 | Medtronic, Inc. | Modular intraluminal prostheses construction and methods |
| US6193745B1 (en) | 1995-10-03 | 2001-02-27 | Medtronic, Inc. | Modular intraluminal prosteheses construction and methods |
| US5716399A (en) | 1995-10-06 | 1998-02-10 | Cardiomend Llc | Methods of heart valve repair |
| US6328763B1 (en) | 1995-10-06 | 2001-12-11 | Cardiomend, Llc | Optimized geometry of a tissue pattern for semilunar heart valve reconstruction |
| EP0859857B1 (en) | 1995-10-25 | 2005-05-04 | OctoPlus B.V. | Cationic polyacrylates and poly(alkyl)acrylates or the corresponding acrylamides for use in synthetic transfection systems |
| US5788626A (en) | 1995-11-21 | 1998-08-04 | Schneider (Usa) Inc | Method of making a stent-graft covered with expanded polytetrafluoroethylene |
| US6042605A (en) | 1995-12-14 | 2000-03-28 | Gore Enterprose Holdings, Inc. | Kink resistant stent-graft |
| US5843158A (en) | 1996-01-05 | 1998-12-01 | Medtronic, Inc. | Limited expansion endoluminal prostheses and methods for their use |
| US5747128A (en) | 1996-01-29 | 1998-05-05 | W. L. Gore & Associates, Inc. | Radially supported polytetrafluoroethylene vascular graft |
| JPH09241412A (ja) | 1996-03-07 | 1997-09-16 | Sumitomo Electric Ind Ltd | 延伸ポリテトラフルオロエチレンチューブとその製造方法 |
| GB2312485B (en) | 1996-04-24 | 1999-10-20 | Endre Bodnar | Bioprosthetic conduits |
| US5628791A (en) | 1996-05-09 | 1997-05-13 | Medical Carbon Research Institute, Llc | Prosthetic trileaflet heart valve |
| DE19625202A1 (de) | 1996-06-24 | 1998-01-02 | Adiam Medizintechnik Gmbh & Co | Prothetische Mitral-Herzklappe |
| US5843161A (en) | 1996-06-26 | 1998-12-01 | Cordis Corporation | Endoprosthesis assembly for percutaneous deployment and method of deploying same |
| US5769884A (en) | 1996-06-27 | 1998-06-23 | Cordis Corporation | Controlled porosity endovascular implant |
| US5749852A (en) | 1996-07-23 | 1998-05-12 | Medtronic, Inc. | Sheath system for autoperfusion dilatation catheter balloon |
| US6174329B1 (en) | 1996-08-22 | 2001-01-16 | Advanced Cardiovascular Systems, Inc. | Protective coating for a stent with intermediate radiopaque coating |
| US5944654A (en) | 1996-11-14 | 1999-08-31 | Vista Medical Technologies, Inc. | Endoscope with replaceable irrigation tube |
| US6261320B1 (en) | 1996-11-21 | 2001-07-17 | Radiance Medical Systems, Inc. | Radioactive vascular liner |
| US6010529A (en) | 1996-12-03 | 2000-01-04 | Atrium Medical Corporation | Expandable shielded vessel support |
| NL1004827C2 (nl) | 1996-12-18 | 1998-06-19 | Surgical Innovations Vof | Inrichting voor het reguleren van de bloedsomloop. |
| EP0850607A1 (en) * | 1996-12-31 | 1998-07-01 | Cordis Corporation | Valve prosthesis for implantation in body channels |
| US5925061A (en) | 1997-01-13 | 1999-07-20 | Gore Enterprise Holdings, Inc. | Low profile vascular stent |
| US5957974A (en) | 1997-01-23 | 1999-09-28 | Schneider (Usa) Inc | Stent graft with braided polymeric sleeve |
| AU746009B2 (en) * | 1997-01-24 | 2002-04-11 | Celonova Stent, Inc | Bistable spring construction for a stent and other medical apparatus |
| GB9701479D0 (en) | 1997-01-24 | 1997-03-12 | Aortech Europ Ltd | Heart valve |
| US5853419A (en) | 1997-03-17 | 1998-12-29 | Surface Genesis, Inc. | Stent |
| US5928281A (en) | 1997-03-27 | 1999-07-27 | Baxter International Inc. | Tissue heart valves |
| US6395024B1 (en) | 1997-05-20 | 2002-05-28 | Triflo Medical, Inc. | Mechanical heart valve |
| CA2235911C (en) | 1997-05-27 | 2003-07-29 | Schneider (Usa) Inc. | Stent and stent-graft for treating branched vessels |
| US6203536B1 (en) | 1997-06-17 | 2001-03-20 | Medtronic, Inc. | Medical device for delivering a therapeutic substance and method therefor |
| US6500174B1 (en) | 1997-07-08 | 2002-12-31 | Atrionix, Inc. | Circumferential ablation device assembly and methods of use and manufacture providing an ablative circumferential band along an expandable member |
| US5919226A (en) | 1997-07-22 | 1999-07-06 | Medtronic, Inc. | Mechanical heart valve prosthesis |
| US6042606A (en) | 1997-09-29 | 2000-03-28 | Cook Incorporated | Radially expandable non-axially contracting surgical stent |
| US6161399A (en) | 1997-10-24 | 2000-12-19 | Iowa-India Investments Company Limited | Process for manufacturing a wire reinforced monolayer fabric stent |
| US5931865A (en) | 1997-11-24 | 1999-08-03 | Gore Enterprise Holdings, Inc. | Multiple-layered leak resistant tube |
| US6626939B1 (en) | 1997-12-18 | 2003-09-30 | Boston Scientific Scimed, Inc. | Stent-graft with bioabsorbable structural support |
| US6190406B1 (en) | 1998-01-09 | 2001-02-20 | Nitinal Development Corporation | Intravascular stent having tapered struts |
| US6488701B1 (en) | 1998-03-31 | 2002-12-03 | Medtronic Ave, Inc. | Stent-graft assembly with thin-walled graft component and method of manufacture |
| US6042588A (en) | 1998-03-03 | 2000-03-28 | Scimed Life Systems, Inc | Stent delivery system |
| US5935162A (en) | 1998-03-16 | 1999-08-10 | Medtronic, Inc. | Wire-tubular hybrid stent |
| US5935163A (en) | 1998-03-31 | 1999-08-10 | Shelhigh, Inc. | Natural tissue heart valve prosthesis |
| JP4222655B2 (ja) | 1998-04-06 | 2009-02-12 | ジャパンゴアテックス株式会社 | 医療用チューブ |
| US6117169A (en) | 1998-06-24 | 2000-09-12 | Sulzer Carbomedics Inc. | Living hinge attachment of leaflet to a valve body |
| EP1089676A2 (en) | 1998-06-24 | 2001-04-11 | Sulzer Carbomedics Inc. | Altering heart valve leaflet attachment geometry to influence the location and magnitude of maximum loaded stress on the leaflet |
| US6217609B1 (en) | 1998-06-30 | 2001-04-17 | Schneider (Usa) Inc | Implantable endoprosthesis with patterned terminated ends and methods for making same |
| US6755856B2 (en) | 1998-09-05 | 2004-06-29 | Abbott Laboratories Vascular Enterprises Limited | Methods and apparatus for stenting comprising enhanced embolic protection, coupled with improved protection against restenosis and thrombus formation |
| US7815763B2 (en) | 2001-09-28 | 2010-10-19 | Abbott Laboratories Vascular Enterprises Limited | Porous membranes for medical implants and methods of manufacture |
| NO984143L (no) | 1998-09-09 | 2000-03-10 | Norsk Hydro As | Ny prosess for å fremstille overflatemodifiserende stoffer |
| US6334873B1 (en) | 1998-09-28 | 2002-01-01 | Autogenics | Heart valve having tissue retention with anchors and an outer sheath |
| US6540780B1 (en) | 1998-11-23 | 2003-04-01 | Medtronic, Inc. | Porous synthetic vascular grafts with oriented ingrowth channels |
| US6336937B1 (en) | 1998-12-09 | 2002-01-08 | Gore Enterprise Holdings, Inc. | Multi-stage expandable stent-graft |
| US6350277B1 (en) | 1999-01-15 | 2002-02-26 | Scimed Life Systems, Inc. | Stents with temporary retaining bands |
| US7049380B1 (en) | 1999-01-19 | 2006-05-23 | Gore Enterprise Holdings, Inc. | Thermoplastic copolymer of tetrafluoroethylene and perfluoromethyl vinyl ether and medical devices employing the copolymer |
| US6673102B1 (en) | 1999-01-22 | 2004-01-06 | Gore Enterprises Holdings, Inc. | Covered endoprosthesis and delivery system |
| WO2000042947A2 (en) | 1999-01-22 | 2000-07-27 | Gore Enterprise Holdings, Inc. | Covered endoprosthesis and delivery system |
| US6736845B2 (en) | 1999-01-26 | 2004-05-18 | Edwards Lifesciences Corporation | Holder for flexible heart valve |
| US6558418B2 (en) | 1999-01-26 | 2003-05-06 | Edwards Lifesciences Corporation | Flexible heart valve |
| WO2000047271A1 (en) | 1999-02-11 | 2000-08-17 | Gore Enterprise Holdings, Inc. | Multiple-layered leak-resistant tube |
| US6245012B1 (en) | 1999-03-19 | 2001-06-12 | Nmt Medical, Inc. | Free standing filter |
| US6283995B1 (en) | 1999-04-15 | 2001-09-04 | Sulzer Carbomedics Inc. | Heart valve leaflet with scalloped free margin |
| US6666885B2 (en) | 1999-04-16 | 2003-12-23 | Carbomedics Inc. | Heart valve leaflet |
| US6283994B1 (en) | 1999-04-16 | 2001-09-04 | Sulzer Carbomedics Inc. | Heart valve leaflet |
| GB2352205A (en) | 1999-06-28 | 2001-01-24 | Nestle Sa | Chilled roller for moulding a food product |
| US20020055773A1 (en) | 1999-07-12 | 2002-05-09 | Louis A. Campbell | Polymer heart valve with insert molded fabric sewing cuff |
| US6174331B1 (en) | 1999-07-19 | 2001-01-16 | Sulzer Carbomedics Inc. | Heart valve leaflet with reinforced free margin |
| US6890350B1 (en) | 1999-07-28 | 2005-05-10 | Scimed Life Systems, Inc. | Combination self-expandable, balloon-expandable endoluminal device |
| EP1253873A2 (en) | 1999-10-16 | 2002-11-06 | Sumit Roy | Low-profile, non-stented prosthesis for transluminal implantation |
| US6673107B1 (en) | 1999-12-06 | 2004-01-06 | Advanced Cardiovascular Systems, Inc. | Bifurcated stent and method of making |
| GB9928905D0 (en) | 1999-12-08 | 2000-02-02 | Aortech Europ Ltd | Prosthesis |
| GB0114345D0 (en) | 2001-06-13 | 2001-08-08 | Aortech Europ Ltd | Heart valve prosthesis and method of manufacture |
| US20030097175A1 (en) | 1999-12-08 | 2003-05-22 | O'connor Bernard | Heart valve prosthesis and method of manufacture |
| US6740962B1 (en) | 2000-02-24 | 2004-05-25 | Micron Technology, Inc. | Tape stiffener, semiconductor device component assemblies including same, and stereolithographic methods for fabricating same |
| US6756094B1 (en) | 2000-02-28 | 2004-06-29 | Scimed Life Systems, Inc. | Balloon structure with PTFE component |
| US6379382B1 (en) | 2000-03-13 | 2002-04-30 | Jun Yang | Stent having cover with drug delivery capability |
| US6436132B1 (en) | 2000-03-30 | 2002-08-20 | Advanced Cardiovascular Systems, Inc. | Composite intraluminal prostheses |
| US6454799B1 (en) | 2000-04-06 | 2002-09-24 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
| US6352552B1 (en) | 2000-05-02 | 2002-03-05 | Scion Cardio-Vascular, Inc. | Stent |
| US6610088B1 (en) | 2000-05-03 | 2003-08-26 | Shlomo Gabbay | Biologically covered heart valve prosthesis |
| US7419678B2 (en) | 2000-05-12 | 2008-09-02 | Cordis Corporation | Coated medical devices for the prevention and treatment of vascular disease |
| US8252044B1 (en) | 2000-11-17 | 2012-08-28 | Advanced Bio Prosthestic Surfaces, Ltd. | Device for in vivo delivery of bioactive agents and method of manufacture thereof |
| US8366769B2 (en) * | 2000-06-01 | 2013-02-05 | Edwards Lifesciences Corporation | Low-profile, pivotable heart valve sewing ring |
| JP5178984B2 (ja) | 2000-07-24 | 2013-04-10 | グレイゼル、ジェフリー | 拡張術およびステント術用の補剛バルーン・カテーテル |
| US6846325B2 (en) | 2000-09-07 | 2005-01-25 | Viacor, Inc. | Fixation band for affixing a prosthetic heart valve to tissue |
| US8784482B2 (en) | 2000-09-20 | 2014-07-22 | Mvrx, Inc. | Method of reshaping a heart valve annulus using an intravascular device |
| ATE346571T1 (de) | 2000-09-21 | 2006-12-15 | St Jude Medical | Ventilprothesen mit blattelementen aus verstärktem kunststoff |
| US6461382B1 (en) | 2000-09-22 | 2002-10-08 | Edwards Lifesciences Corporation | Flexible heart valve having moveable commissures |
| US6482228B1 (en) | 2000-11-14 | 2002-11-19 | Troy R. Norred | Percutaneous aortic valve replacement |
| US6974476B2 (en) | 2003-05-05 | 2005-12-13 | Rex Medical, L.P. | Percutaneous aortic valve |
| US6953332B1 (en) | 2000-11-28 | 2005-10-11 | St. Jude Medical, Inc. | Mandrel for use in forming valved prostheses having polymer leaflets by dip coating |
| US8690910B2 (en) | 2000-12-07 | 2014-04-08 | Integrated Vascular Systems, Inc. | Closure device and methods for making and using them |
| GB2369981B (en) | 2000-12-13 | 2004-05-26 | Alexander James Sandall | Horticultural chamber |
| DE10061936A1 (de) | 2000-12-13 | 2002-07-04 | Valentin Kramer | Gegenstand aus ePTFE und Verfahren zum Herstellen desselben |
| US6454798B1 (en) | 2000-12-21 | 2002-09-24 | Sulzer Carbomedics Inc. | Polymer heart valve with helical coaption surface |
| US7083642B2 (en) | 2000-12-22 | 2006-08-01 | Avantec Vascular Corporation | Delivery of therapeutic capable agents |
| US20070027535A1 (en) | 2005-07-28 | 2007-02-01 | Cook Incorporated | Implantable thromboresistant valve |
| WO2002074201A1 (en) | 2001-03-16 | 2002-09-26 | Mayo Foundation For Medical Education And Research | Synthethic leaflets for heart valve repair or replacement |
| US6761733B2 (en) | 2001-04-11 | 2004-07-13 | Trivascular, Inc. | Delivery system and method for bifurcated endovascular graft |
| US6936067B2 (en) | 2001-05-17 | 2005-08-30 | St. Jude Medical Inc. | Prosthetic heart valve with slit stent |
| US6716239B2 (en) | 2001-07-03 | 2004-04-06 | Scimed Life Systems, Inc. | ePTFE graft with axial elongation properties |
| AU2002320610A1 (en) | 2001-07-16 | 2003-03-03 | Altertek/Bio Inc | Tissue engineered heart valve |
| EP1414369A2 (en) | 2001-07-27 | 2004-05-06 | Medtronic, Inc. | Adventitial fabric reinforced porous prosthetic graft |
| US7288105B2 (en) | 2001-08-01 | 2007-10-30 | Ev3 Endovascular, Inc. | Tissue opening occluder |
| US6562069B2 (en) | 2001-09-19 | 2003-05-13 | St. Jude Medical, Inc. | Polymer leaflet designs for medical devices |
| US6827737B2 (en) | 2001-09-25 | 2004-12-07 | Scimed Life Systems, Inc. | EPTFE covering for endovascular prostheses and method of manufacture |
| EP1450727B1 (en) | 2001-10-04 | 2010-06-16 | Neovasc Medical Ltd. | Flow reducing implant |
| US6893460B2 (en) | 2001-10-11 | 2005-05-17 | Percutaneous Valve Technologies Inc. | Implantable prosthetic valve |
| US6541589B1 (en) | 2001-10-15 | 2003-04-01 | Gore Enterprise Holdings, Inc. | Tetrafluoroethylene copolymer |
| US6726715B2 (en) | 2001-10-23 | 2004-04-27 | Childrens Medical Center Corporation | Fiber-reinforced heart valve prosthesis |
| US6755857B2 (en) | 2001-12-12 | 2004-06-29 | Sulzer Carbomedics Inc. | Polymer heart valve with perforated stent and sewing cuff |
| US7033390B2 (en) | 2002-01-02 | 2006-04-25 | Medtronic, Inc. | Prosthetic heart valve system |
| US6946173B2 (en) | 2002-03-21 | 2005-09-20 | Advanced Cardiovascular Systems, Inc. | Catheter balloon formed of ePTFE and a diene polymer |
| US7163556B2 (en) | 2002-03-21 | 2007-01-16 | Providence Health System - Oregon | Bioprosthesis and method for suturelessly making same |
| EP1487353A4 (en) | 2002-03-25 | 2008-04-16 | Nmt Medical Inc | FORAMEN OVAL PERSISTENT CLOSURE CLAMPS (PFO) |
| AU2003223749A1 (en) | 2002-04-25 | 2003-11-10 | The Board Of Trustees Of The Leland Stanford Junior University | Expandable guide sheath and apparatus and methods using such sheaths |
| WO2003092554A1 (en) | 2002-05-03 | 2003-11-13 | The General Hospital Corporation | Involuted endovascular valve and method of construction |
| US7270675B2 (en) | 2002-05-10 | 2007-09-18 | Cordis Corporation | Method of forming a tubular membrane on a structural frame |
| US20030229394A1 (en) | 2002-06-06 | 2003-12-11 | Ogle Matthew F. | Processed tissue for medical device formation |
| US7789908B2 (en) | 2002-06-25 | 2010-09-07 | Boston Scientific Scimed, Inc. | Elastomerically impregnated ePTFE to enhance stretch and recovery properties for vascular grafts and coverings |
| US20040024448A1 (en) | 2002-08-05 | 2004-02-05 | Chang James W. | Thermoplastic fluoropolymer-coated medical devices |
| US20040026245A1 (en) | 2002-08-09 | 2004-02-12 | Vivek Agarwal | High temperature oleophobic materials |
| CA2494970C (en) * | 2002-08-15 | 2009-12-29 | Cook Incorporated | Stent and method of forming a stent with integral barbs |
| EP1550477B1 (en) | 2002-08-23 | 2015-11-04 | National Cerebral and Cardiovascular Center | Stent and process for producing the same |
| US7273492B2 (en) | 2002-08-27 | 2007-09-25 | Advanced Cardiovascular Systems Inc. | Stent for treating vulnerable plaque |
| US6878162B2 (en) | 2002-08-30 | 2005-04-12 | Edwards Lifesciences Ag | Helical stent having improved flexibility and expandability |
| US7879085B2 (en) | 2002-09-06 | 2011-02-01 | Boston Scientific Scimed, Inc. | ePTFE crimped graft |
| US7137184B2 (en) | 2002-09-20 | 2006-11-21 | Edwards Lifesciences Corporation | Continuous heart valve support frame and method of manufacture |
| US7001425B2 (en) | 2002-11-15 | 2006-02-21 | Scimed Life Systems, Inc. | Braided stent method for its manufacture |
| US7105018B1 (en) | 2002-12-30 | 2006-09-12 | Advanced Cardiovascular Systems, Inc. | Drug-eluting stent cover and method of use |
| US9125733B2 (en) | 2003-01-14 | 2015-09-08 | The Cleveland Clinic Foundation | Branched vessel endoluminal device |
| KR20050098945A (ko) | 2003-02-19 | 2005-10-12 | 듀폰-미쯔이 플루오로케미칼 가부시끼가이샤 | 불소 수지 복합체 조성물 |
| US20070207816A1 (en) | 2003-02-24 | 2007-09-06 | Polaris Wireless, Inc. | Location Estimation of Wireless Terminals Based on Combinations of Signal-Strength Measurements and Geometry-of-Arrival Measurements |
| US7658759B2 (en) | 2003-04-24 | 2010-02-09 | Cook Incorporated | Intralumenally implantable frames |
| US7128759B2 (en) | 2003-05-19 | 2006-10-31 | Cook Incorporated | Implantable medical device with constrained expansion |
| US7011646B2 (en) | 2003-06-24 | 2006-03-14 | Advanced Cardiovascular Systems, Inc. | Balloon catheter having a balloon with a thickened wall portion |
| JP4432400B2 (ja) | 2003-07-25 | 2010-03-17 | 日産自動車株式会社 | 燃料電池システムの制御装置 |
| WO2005011534A1 (en) | 2003-07-31 | 2005-02-10 | Cook Incorporated | Prosthetic valve devices and methods of making such devices |
| US7967829B2 (en) | 2003-10-09 | 2011-06-28 | Boston Scientific Scimed, Inc. | Medical device delivery system |
| FR2863160B1 (fr) | 2003-12-09 | 2006-03-03 | Perouse Laboratoires | Dispositif de traitement d'un vaisseau sanguin et procede de preparation de ce dispositif |
| US8128681B2 (en) | 2003-12-19 | 2012-03-06 | Boston Scientific Scimed, Inc. | Venous valve apparatus, system, and method |
| US7261732B2 (en) | 2003-12-22 | 2007-08-28 | Henri Justino | Stent mounted valve |
| US7763011B2 (en) | 2003-12-22 | 2010-07-27 | Boston Scientific Scimed, Inc. | Variable density braid stent |
| US7780725B2 (en) | 2004-06-16 | 2010-08-24 | Sadra Medical, Inc. | Everting heart valve |
| US9005273B2 (en) | 2003-12-23 | 2015-04-14 | Sadra Medical, Inc. | Assessing the location and performance of replacement heart valves |
| AU2004308508B2 (en) | 2003-12-23 | 2011-03-10 | Sadra Medical, Inc. | Repositionable heart valve |
| US20050137686A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delaware Corporation | Externally expandable heart valve anchor and method |
| US7871435B2 (en) | 2004-01-23 | 2011-01-18 | Edwards Lifesciences Corporation | Anatomically approximate prosthetic mitral heart valve |
| US7862610B2 (en) | 2004-01-23 | 2011-01-04 | James Quintessenza | Bicuspid vascular valve and methods for making and implanting same |
| US7247167B2 (en) | 2004-02-19 | 2007-07-24 | Shlomo Gabbay | Low profile heart valve prosthesis |
| US8128692B2 (en) | 2004-02-27 | 2012-03-06 | Aortx, Inc. | Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same |
| EP1725188A1 (en) | 2004-03-02 | 2006-11-29 | Boston Scientific Scimed, Inc. | Medical devices including metallic films and methods for making same |
| MXPA06006905A (es) | 2004-04-08 | 2008-02-13 | Aga Medical Corp | Dispositivo de oclusion rebordeado y metodos. |
| US20060122693A1 (en) | 2004-05-10 | 2006-06-08 | Youssef Biadillah | Stent valve and method of manufacturing same |
| US7794490B2 (en) | 2004-06-22 | 2010-09-14 | Boston Scientific Scimed, Inc. | Implantable medical devices with antimicrobial and biodegradable matrices |
| US7276078B2 (en) | 2004-06-30 | 2007-10-02 | Edwards Lifesciences Pvt | Paravalvular leak detection, sealing, and prevention |
| EP1768612A1 (en) | 2004-07-07 | 2007-04-04 | Cook Incorporated | Graft, stent graft and method for manufacture |
| US20060008497A1 (en) | 2004-07-09 | 2006-01-12 | Shlomo Gabbay | Implantable apparatus having improved biocompatibility and process of making the same |
| US8308789B2 (en) | 2004-07-16 | 2012-11-13 | W. L. Gore & Associates, Inc. | Deployment system for intraluminal devices |
| US20060134074A1 (en) | 2004-08-30 | 2006-06-22 | Naughton Gail K | Compositions and methods for promoting hair growth |
| FR2874812B1 (fr) | 2004-09-07 | 2007-06-15 | Perouse Soc Par Actions Simpli | Valve protheique interchangeable |
| US8029563B2 (en) | 2004-11-29 | 2011-10-04 | Gore Enterprise Holdings, Inc. | Implantable devices with reduced needle puncture site leakage |
| US8262720B2 (en) | 2004-12-02 | 2012-09-11 | Nitinol Development Corporation | Prosthesis comprising dual tapered stent |
| US7758640B2 (en) | 2004-12-16 | 2010-07-20 | Valvexchange Inc. | Cardiovascular valve assembly |
| US20060135985A1 (en) | 2004-12-21 | 2006-06-22 | Cox Daniel L | Vulnerable plaque modification methods and apparatuses |
| US20060161241A1 (en) | 2005-01-14 | 2006-07-20 | Denise Barbut | Methods and devices for treating aortic atheroma |
| US20060190070A1 (en) | 2005-02-23 | 2006-08-24 | Dieck Martin S | Rail stent and methods of use |
| US8303647B2 (en) | 2005-03-03 | 2012-11-06 | Cook Medical Technologies Llc | Medical valve leaflet structures with peripheral region receptive to tissue ingrowth |
| US8062359B2 (en) | 2005-04-06 | 2011-11-22 | Edwards Lifesciences Corporation | Highly flexible heart valve connecting band |
| US7513909B2 (en) | 2005-04-08 | 2009-04-07 | Arbor Surgical Technologies, Inc. | Two-piece prosthetic valves with snap-in connection and methods for use |
| US7914569B2 (en) | 2005-05-13 | 2011-03-29 | Medtronics Corevalve Llc | Heart valve prosthesis and methods of manufacture and use |
| WO2006125055A2 (en) | 2005-05-17 | 2006-11-23 | Cook Incorporated | Prosthetic valve devices and methods of making and using such devices |
| US7799072B2 (en) | 2005-05-20 | 2010-09-21 | The Cleveland Clinic Foundation | Apparatus and methods for repairing the function of a diseased valve and method for making same |
| EP3292838A1 (en) | 2005-05-24 | 2018-03-14 | Edwards Lifesciences Corporation | Rapid deployment prosthetic heart valve |
| EP3482717B1 (en) | 2005-05-27 | 2023-09-06 | Edwards Lifesciences Corporation | Stentless support structure |
| US20060276883A1 (en) | 2005-06-01 | 2006-12-07 | Cook Incorporated | Tapered and distally stented elephant trunk stent graft |
| US7238200B2 (en) | 2005-06-03 | 2007-07-03 | Arbor Surgical Technologies, Inc. | Apparatus and methods for making leaflets and valve prostheses including such leaflets |
| US8267993B2 (en) | 2005-06-09 | 2012-09-18 | Coroneo, Inc. | Expandable annuloplasty ring and associated ring holder |
| FR2887139B1 (fr) | 2005-06-15 | 2008-04-25 | Perouse Soc Par Actions Simpli | Dispositif de traitement d'un vaisseau sanguin. |
| US7531611B2 (en) | 2005-07-05 | 2009-05-12 | Gore Enterprise Holdings, Inc. | Copolymers of tetrafluoroethylene |
| US7306729B2 (en) | 2005-07-18 | 2007-12-11 | Gore Enterprise Holdings, Inc. | Porous PTFE materials and articles produced therefrom |
| DE602006012687D1 (de) | 2005-08-17 | 2010-04-15 | Bard Inc C R | Stentabgabesystem mit variabler geschwindigkeit |
| US8956400B2 (en) | 2005-10-14 | 2015-02-17 | Flexible Stenting Solutions, Inc. | Helical stent |
| US7563277B2 (en) | 2005-10-24 | 2009-07-21 | Cook Incorporated | Removable covering for implantable frame projections |
| EP1948088A2 (en) | 2005-11-18 | 2008-07-30 | Innovia LLC | Trileaflet heart valve |
| US20070142907A1 (en) | 2005-12-16 | 2007-06-21 | Micardia Corporation | Adjustable prosthetic valve implant |
| EP3398560B8 (en) * | 2005-12-22 | 2024-01-10 | Boston Scientific Medical Device Limited | Systems for surgery and stent valves for replacement |
| US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
| WO2007075892A2 (en) | 2005-12-23 | 2007-07-05 | Clinasys Llc | An implantable prosthetic valve |
| EP1965730A4 (en) | 2005-12-30 | 2009-06-17 | Bard Inc C R | VASCULAR STENT WITH BIORESORBABLE CONNECTOR AND METHODS |
| WO2007083288A2 (en) | 2006-01-23 | 2007-07-26 | Atria Medical Inc. | Heart anchor device |
| FR2896405B1 (fr) | 2006-01-24 | 2008-04-18 | Perouse Soc Par Actions Simpli | Dispositif de traitement d'un conduit de circulation du sang et procede de preparation associe |
| ES2335520T3 (es) | 2006-02-24 | 2010-03-29 | National University Of Ireland, Galway | Dispositivo de tratamiento intravascular minimamente invasivo. |
| EP1991164B1 (en) | 2006-02-28 | 2017-06-14 | Angiomed GmbH & Co. Medizintechnik KG | Flexible stretch stent-graft |
| US8025693B2 (en) | 2006-03-01 | 2011-09-27 | Boston Scientific Scimed, Inc. | Stent-graft having flexible geometries and methods of producing the same |
| US8585753B2 (en) | 2006-03-04 | 2013-11-19 | John James Scanlon | Fibrillated biodegradable prosthesis |
| US8721704B2 (en) | 2006-04-21 | 2014-05-13 | W. L. Gore & Associates, Inc. | Expandable stent with wrinkle-free elastomeric cover |
| US8425584B2 (en) | 2006-04-21 | 2013-04-23 | W. L. Gore & Associates, Inc. | Expandable covered stent with wide range of wrinkle-free deployed diameters |
| US20070254012A1 (en) | 2006-04-28 | 2007-11-01 | Ludwig Florian N | Controlled degradation and drug release in stents |
| US9114194B2 (en) | 2006-05-12 | 2015-08-25 | W. L. Gore & Associates, Inc. | Immobilized biologically active entities having high biological activity following mechanical manipulation |
| US20080026190A1 (en) | 2006-07-28 | 2008-01-31 | General Electric Company | Durable membranes and methods for improving membrane durability |
| US20080140173A1 (en) | 2006-08-07 | 2008-06-12 | Sherif Eskaros | Non-shortening wrapped balloon |
| US7785290B2 (en) | 2006-08-07 | 2010-08-31 | Gore Enterprise Holdings, Inc. | Non-shortening high angle wrapped balloons |
| US8882826B2 (en) | 2006-08-22 | 2014-11-11 | Abbott Cardiovascular Systems Inc. | Intravascular stent |
| US8500793B2 (en) | 2006-09-07 | 2013-08-06 | C. R. Bard, Inc. | Helical implant having different ends |
| US8834564B2 (en) | 2006-09-19 | 2014-09-16 | Medtronic, Inc. | Sinus-engaging valve fixation member |
| US8876894B2 (en) | 2006-09-19 | 2014-11-04 | Medtronic Ventor Technologies Ltd. | Leaflet-sensitive valve fixation member |
| CA2663573C (en) | 2006-09-21 | 2015-04-07 | Cleveny Technologies | A specially configured and surface modified medical device with certain design features that utilize the intrinsic properties of tungsten, zirconium, tantalum and/or niobium |
| US20080097401A1 (en) | 2006-09-22 | 2008-04-24 | Trapp Benjamin M | Cerebral vasculature device |
| JP2010504820A (ja) | 2006-09-28 | 2010-02-18 | クック・インコーポレイテッド | 胸部大動脈瘤を修復するための装置および方法 |
| US8545545B2 (en) | 2006-10-18 | 2013-10-01 | Innovational Holdings Llc | Stent with flexible hinges |
| US20080097582A1 (en) | 2006-10-18 | 2008-04-24 | Conor Medsystems, Inc. | Stent with flexible hinges |
| CN101172059B (zh) | 2006-10-31 | 2010-12-08 | 温宁 | 带内层舌状结构的支架瓣膜及其支架的编织方法 |
| US9622888B2 (en) | 2006-11-16 | 2017-04-18 | W. L. Gore & Associates, Inc. | Stent having flexibly connected adjacent stent elements |
| WO2008066923A1 (en) | 2006-11-30 | 2008-06-05 | William Cook Europe Aps | Implant release mechanism |
| US8133270B2 (en) * | 2007-01-08 | 2012-03-13 | California Institute Of Technology | In-situ formation of a valve |
| US7731783B2 (en) | 2007-01-24 | 2010-06-08 | Pratt & Whitney Rocketdyne, Inc. | Continuous pressure letdown system |
| US9415567B2 (en) | 2007-02-05 | 2016-08-16 | Boston Scientific Scimed, Inc. | Synthetic composite structures |
| ES2441801T3 (es) * | 2007-02-05 | 2014-02-06 | Boston Scientific Limited | Válvula percutánea y sistema de suministro |
| JP2010517625A (ja) | 2007-02-05 | 2010-05-27 | ボストン サイエンティフィック リミテッド | 合成複合材料構造 |
| JP2010517703A (ja) | 2007-02-09 | 2010-05-27 | タヘリ ラドュカ エルエルシー | 血管移植片およびそれを加工する方法 |
| CA2677648C (en) | 2007-02-16 | 2015-10-27 | Medtronic, Inc. | Replacement prosthetic heart valves and methods of implantation |
| US20080208327A1 (en) | 2007-02-27 | 2008-08-28 | Rowe Stanton J | Method and apparatus for replacing a prosthetic valve |
| US7914807B2 (en) | 2007-03-05 | 2011-03-29 | Boston Scientific Scimed, Inc. | Medical devices having improved performance |
| US8092523B2 (en) | 2007-03-12 | 2012-01-10 | St. Jude Medical, Inc. | Prosthetic heart valves with flexible leaflets |
| US8409274B2 (en) | 2007-04-26 | 2013-04-02 | St. Jude Medical, Inc. | Techniques for attaching flexible leaflets of prosthetic heart valves to supporting structures |
| FR2915678B1 (fr) | 2007-05-02 | 2010-04-16 | Lapeyre Ind Llc | Valve cardiaque prothetique mecanique |
| CN100502811C (zh) * | 2007-05-29 | 2009-06-24 | 中国人民解放军第二军医大学 | 一种带瓣膜肺动脉支架 |
| JP5367700B2 (ja) | 2007-06-04 | 2013-12-11 | セント ジュード メディカル インコーポレイテッド | 人工心臓弁 |
| US8057531B2 (en) | 2007-06-29 | 2011-11-15 | Abbott Cardiovascular Systems Inc. | Stent having circumferentially deformable struts |
| US7815677B2 (en) | 2007-07-09 | 2010-10-19 | Leman Cardiovascular Sa | Reinforcement device for a biological valve and reinforced biological valve |
| US9669191B2 (en) | 2008-02-05 | 2017-06-06 | Silk Road Medical, Inc. | Interventional catheter system and methods |
| CN101091675B (zh) | 2007-07-19 | 2010-06-16 | 中国人民解放军第二军医大学 | 双盘状带人工瓣膜房室瓣支架 |
| US20100094405A1 (en) | 2008-10-10 | 2010-04-15 | Orbusneich Medical, Inc. | Bioabsorbable Polymeric Medical Device |
| US7988723B2 (en) | 2007-08-02 | 2011-08-02 | Flexible Stenting Solutions, Inc. | Flexible stent |
| EP2484311B1 (en) | 2007-08-24 | 2015-05-06 | St. Jude Medical, Inc. | Prosthetic aortic heart valve |
| BRPI0817708A2 (pt) | 2007-09-26 | 2017-05-16 | St Jude Medical | válvula cardíaca protética, e, estrutura de lamela para a mesma. |
| US8454686B2 (en) | 2007-09-28 | 2013-06-04 | St. Jude Medical, Inc. | Two-stage collapsible/expandable prosthetic heart valves and anchoring systems |
| WO2009045334A1 (en) | 2007-09-28 | 2009-04-09 | St. Jude Medical, Inc. | Collapsible/expandable prosthetic heart valves with native calcified leaflet retention features |
| US7803186B1 (en) | 2007-09-28 | 2010-09-28 | St. Jude Medical, Inc. | Prosthetic heart valves with flexible leaflets and leaflet edge clamping |
| US8637144B2 (en) | 2007-10-04 | 2014-01-28 | W. L. Gore & Associates, Inc. | Expandable TFE copolymers, method of making, and porous, expended articles thereof |
| US20090138079A1 (en) | 2007-10-10 | 2009-05-28 | Vector Technologies Ltd. | Prosthetic heart valve for transfemoral delivery |
| US8679519B2 (en) | 2007-10-23 | 2014-03-25 | Abbott Cardiovascular Systems Inc. | Coating designs for the tailored release of dual drugs from polymeric coatings |
| EP2231070B1 (en) | 2007-12-14 | 2013-05-22 | Edwards Lifesciences Corporation | Leaflet attachment frame for a prosthetic valve |
| US8317857B2 (en) | 2008-01-10 | 2012-11-27 | Telesis Research, Llc | Biodegradable self-expanding prosthesis |
| US8926688B2 (en) | 2008-01-11 | 2015-01-06 | W. L. Gore & Assoc. Inc. | Stent having adjacent elements connected by flexible webs |
| EP2254513B1 (en) | 2008-01-24 | 2015-10-28 | Medtronic, Inc. | Stents for prosthetic heart valves |
| US8398704B2 (en) | 2008-02-26 | 2013-03-19 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| WO2009108355A1 (en) | 2008-02-28 | 2009-09-03 | Medtronic, Inc. | Prosthetic heart valve systems |
| US9241792B2 (en) | 2008-02-29 | 2016-01-26 | Edwards Lifesciences Corporation | Two-step heart valve implantation |
| DE102008012113A1 (de) | 2008-03-02 | 2009-09-03 | Transcatheter Technologies Gmbh | Stent, welcher vom expandierten Zustand erneut im Durchmesser kontrolliert verringerbar ist |
| US8313525B2 (en) | 2008-03-18 | 2012-11-20 | Medtronic Ventor Technologies, Ltd. | Valve suturing and implantation procedures |
| EP2106820A1 (en) | 2008-03-31 | 2009-10-07 | Torsten Heilmann | Expansible biocompatible coats comprising a biologically active substance |
| US20090287305A1 (en) | 2008-05-19 | 2009-11-19 | Amalaha Leonard D | Wholly implantable non-natural heart for humans |
| CA2835521C (en) | 2008-06-04 | 2016-04-19 | Gore Enterprise Holdings, Inc. | Controlled deployable medical device and method of making the same |
| CA3272264A1 (en) | 2008-06-06 | 2025-10-30 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
| US20110160836A1 (en) | 2008-06-20 | 2011-06-30 | Vysera Biomedical Limited | Valve device |
| WO2009153771A1 (en) | 2008-06-20 | 2009-12-23 | Vysera Biomedical Limited | Esophageal valve |
| EP2145917B1 (en) | 2008-07-17 | 2012-06-06 | W.L. Gore & Associates GmbH | Polymer coating comprising a complex of an ionic fluoropolyether and a counter ionic agent |
| BRPI0822756B8 (pt) * | 2008-07-17 | 2021-06-22 | Nvt Ag | sistema de prótese de válvula cardíaca e processo para produzir prótese de válvula cardíaca |
| WO2010011878A2 (en) | 2008-07-24 | 2010-01-28 | Cook Incorporated | Valve device with biased leaflets |
| JP2012501803A (ja) | 2008-09-10 | 2012-01-26 | イーブイ3 インコーポレイテッド | 改良ステント配備を有するステントおよびカテーテル |
| CN102292053A (zh) | 2008-09-29 | 2011-12-21 | 卡迪尔克阀门技术公司 | 心脏瓣膜 |
| US9149376B2 (en) | 2008-10-06 | 2015-10-06 | Cordis Corporation | Reconstrainable stent delivery system |
| WO2010048177A2 (en) | 2008-10-20 | 2010-04-29 | IMDS, Inc. | Systems and methods for aneurysm treatment and vessel occlusion |
| WO2010057262A1 (en) | 2008-11-21 | 2010-05-27 | Percutaneous Cardiovascular Solutions Pty Limited | Heart valve prosthesis and method |
| US8591573B2 (en) | 2008-12-08 | 2013-11-26 | Hector Daniel Barone | Prosthetic valve for intraluminal implantation |
| US7968190B2 (en) | 2008-12-19 | 2011-06-28 | Gore Enterprise Holdings, Inc. | PTFE fabric articles and method of making same |
| US8764813B2 (en) | 2008-12-23 | 2014-07-01 | Cook Medical Technologies Llc | Gradually self-expanding stent |
| EP3181096B1 (en) | 2009-02-25 | 2025-10-08 | JenaValve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US20100217382A1 (en) | 2009-02-25 | 2010-08-26 | Edwards Lifesciences | Mitral valve replacement with atrial anchoring |
| US9139669B2 (en) | 2009-03-24 | 2015-09-22 | W. L. Gore & Associates, Inc. | Expandable functional TFE copolymer fine powder, the expandable functional products obtained therefrom and reaction of the expanded products |
| GB0906065D0 (en) | 2009-04-07 | 2009-05-20 | Angiomed Ag | Delivery system for a prosthesis |
| US8888836B2 (en) | 2009-04-07 | 2014-11-18 | Medtronic Vascular, Inc. | Implantable temporary flow restrictor device |
| AU2010236288A1 (en) | 2009-04-15 | 2011-10-20 | Cardiaq Valve Technologies, Inc. | Vascular implant and delivery system |
| KR101314224B1 (ko) | 2009-04-24 | 2013-10-04 | 플렉서블 스텐딩 솔루션즈 인크 | 플렉서블 장치 |
| US9572693B2 (en) | 2009-05-14 | 2017-02-21 | Orbusneich Medical, Inc. | Self-expanding stent with polygon transition zone |
| CA3009244C (en) | 2009-06-23 | 2020-04-28 | Endospan Ltd. | Vascular prostheses for treating aneurysms |
| WO2010151382A1 (en) | 2009-06-26 | 2010-12-29 | Wilson-Cook Medical Inc. | Linear clamps for anastomosis |
| DE102009037739A1 (de) | 2009-06-29 | 2010-12-30 | Be Innovative Gmbh | Perkutan implantierbarer Klappenstent, Vorrichtung zu seiner Applizierung sowie Verfahren zur Herstellung des Klappenstents |
| US9327060B2 (en) | 2009-07-09 | 2016-05-03 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Rapamycin reservoir eluting stent |
| US8435282B2 (en) | 2009-07-15 | 2013-05-07 | W. L. Gore & Associates, Inc. | Tube with reverse necking properties |
| US8936634B2 (en) | 2009-07-15 | 2015-01-20 | W. L. Gore & Associates, Inc. | Self constraining radially expandable medical devices |
| US20110054515A1 (en) | 2009-08-25 | 2011-03-03 | John Bridgeman | Device and method for occluding the left atrial appendage |
| JP5744028B2 (ja) * | 2009-08-27 | 2015-07-01 | メドトロニック,インコーポレイテッド | 経カテーテル弁搬送システムおよび方法 |
| AU2010286524B2 (en) | 2009-08-28 | 2014-09-04 | Medtronic 3F Therapeutics, Inc. | Surgical delivery device and method of use |
| US8591932B2 (en) | 2009-09-17 | 2013-11-26 | W. L. Gore & Associates, Inc. | Heparin entities and methods of use |
| US9730790B2 (en) | 2009-09-29 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Replacement valve and method |
| US8474120B2 (en) | 2009-10-09 | 2013-07-02 | W. L. Gore & Associates, Inc. | Bifurcated highly conformable medical device branch access |
| EP3308816B1 (en) | 2009-10-29 | 2020-02-12 | W.L. Gore & Associates, Inc | Syringe stopper coated with densified expanded ptfe |
| AU2010315651B2 (en) | 2009-11-03 | 2014-08-07 | Cook Medical Technologies Llc | Planar clamps for anastomosis |
| GR1007028B (el) | 2009-11-11 | 2010-10-22 | Ευσταθιος-Ανδρεας Αγαθος | Υποστηρικτης βιοπροσθετικων βαλβιδων με διαγλωχινικο συνδεσμο σχηματος καρδιας |
| US20130190861A1 (en) | 2012-01-23 | 2013-07-25 | Tendyne Holdings, Inc. | Prosthetic Valve for Replacing Mitral Valve |
| US9504562B2 (en) | 2010-01-12 | 2016-11-29 | Valve Medical Ltd. | Self-assembling modular percutaneous valve and methods of folding, assembly and delivery |
| EP2533821B1 (en) | 2010-02-12 | 2016-07-13 | Aesculap AG | Medical device made of eptfe partially coated with an antimicrobial material |
| US9522062B2 (en) | 2010-02-24 | 2016-12-20 | Medtronic Ventor Technologies, Ltd. | Mitral prosthesis and methods for implantation |
| US9226826B2 (en) | 2010-02-24 | 2016-01-05 | Medtronic, Inc. | Transcatheter valve structure and methods for valve delivery |
| WO2011109450A2 (en) | 2010-03-01 | 2011-09-09 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve and methods associated therewith |
| US8795354B2 (en) * | 2010-03-05 | 2014-08-05 | Edwards Lifesciences Corporation | Low-profile heart valve and delivery system |
| US9833314B2 (en) | 2010-04-16 | 2017-12-05 | Abiomed, Inc. | Percutaneous valve deployment |
| RU2434604C1 (ru) | 2010-04-30 | 2011-11-27 | Лео Антонович Бокерия | Аортальный трехстворчатый протез клапана сердца |
| US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
| US8986374B2 (en) | 2010-05-10 | 2015-03-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
| CN103002833B (zh) * | 2010-05-25 | 2016-05-11 | 耶拿阀门科技公司 | 人工心脏瓣及包括人工心脏瓣和支架的经导管输送的内假体 |
| FI126855B (fi) | 2010-07-08 | 2017-06-30 | Aalto-Korkeakoulusäätiö | Menetelmä ja laitteisto orgaanisten liuottimien ja alkoholien tuottamiseksi mikrobeilla |
| CN101926699A (zh) | 2010-07-13 | 2010-12-29 | 北京迈迪顶峰医疗科技有限公司 | 房间隔造孔支架及其输送器 |
| EP2596765B1 (en) | 2010-07-20 | 2017-01-04 | Kyoto Medical Planning Co., Ltd. | Stent device |
| EP2598044B1 (en) | 2010-07-27 | 2019-03-13 | Incept, LLC | Apparatus for treating neurovascular venous outflow obstruction |
| CN201744060U (zh) | 2010-08-17 | 2011-02-16 | 天健医疗科技(苏州)有限公司 | 阶梯型动脉球囊扩张导管 |
| US8808848B2 (en) | 2010-09-10 | 2014-08-19 | W. L. Gore & Associates, Inc. | Porous article |
| AU2011305153A1 (en) | 2010-09-23 | 2013-05-02 | Colibri Heart Valve Llc | Percutaneously deliverable heart or blood vessel valve with frame having abluminally situated tissue membrane |
| US8845720B2 (en) | 2010-09-27 | 2014-09-30 | Edwards Lifesciences Corporation | Prosthetic heart valve frame with flexible commissures |
| CN105380730B (zh) | 2010-10-05 | 2018-08-17 | 爱德华兹生命科学公司 | 人工心脏瓣膜 |
| PL3593762T3 (pl) | 2010-10-05 | 2021-05-04 | Edwards Lifesciences Corporation | Zastawka protetyczna serca i urządzenie do wprowadzania |
| US20120116498A1 (en) | 2010-11-05 | 2012-05-10 | Chuter Timothy A | Aortic valve prostheses |
| US20120116496A1 (en) | 2010-11-05 | 2012-05-10 | Chuter Timothy A | Stent structures for use with valve replacements |
| US9468547B2 (en) | 2010-11-11 | 2016-10-18 | W. L. Gore & Associates, Inc. | Deployment of endoluminal devices |
| SG191008A1 (en) * | 2010-12-14 | 2013-07-31 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets |
| DE102010061371A1 (de) | 2010-12-20 | 2012-06-21 | Transcatheter Technologies Gmbh | Vorrichtung mit individuellen Schaftfasern und Set zum Falten oder Entfalten eines medizinischen Implantats und Verfahren |
| US9198787B2 (en) | 2010-12-31 | 2015-12-01 | Cook Medical Technologies Llc | Conformable prosthesis delivery system and method for deployment thereof |
| CN103533911A (zh) | 2011-01-13 | 2014-01-22 | 因诺维亚有限责任公司 | 腔内涂药器及治疗身体的患病脉管的方法 |
| US9839540B2 (en) | 2011-01-14 | 2017-12-12 | W. L. Gore & Associates, Inc. | Stent |
| US10166128B2 (en) | 2011-01-14 | 2019-01-01 | W. L. Gore & Associates. Inc. | Lattice |
| AU2012207362B2 (en) | 2011-01-18 | 2016-07-14 | Loma Vista Medical, Inc. | Inflatable medical devices |
| GB2488530A (en) | 2011-02-18 | 2012-09-05 | David J Wheatley | Heart valve |
| US9155619B2 (en) | 2011-02-25 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
| EP2683420B1 (en) | 2011-03-11 | 2018-05-23 | W. L. Gore & Associates, Inc. | Improvements to immobilised biological entities |
| US20140163673A1 (en) | 2011-04-01 | 2014-06-12 | W. L. Gore & Associates, Inc. | Prosthetic heart valve leaflet adapted for external imaging |
| US9801712B2 (en) | 2011-04-01 | 2017-10-31 | W. L. Gore & Associates, Inc. | Coherent single layer high strength synthetic polymer composites for prosthetic valves |
| US20140163671A1 (en) | 2011-04-01 | 2014-06-12 | W. L. Gore & Associates, Inc. | Leaflet and valve apparatus |
| US9554900B2 (en) | 2011-04-01 | 2017-01-31 | W. L. Gore & Associates, Inc. | Durable high strength polymer composites suitable for implant and articles produced therefrom |
| US8961599B2 (en) | 2011-04-01 | 2015-02-24 | W. L. Gore & Associates, Inc. | Durable high strength polymer composite suitable for implant and articles produced therefrom |
| US8945212B2 (en) | 2011-04-01 | 2015-02-03 | W. L. Gore & Associates, Inc. | Durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom |
| US9744033B2 (en) | 2011-04-01 | 2017-08-29 | W.L. Gore & Associates, Inc. | Elastomeric leaflet for prosthetic heart valves |
| EP2522308B1 (de) | 2011-05-10 | 2015-02-25 | Biotronik AG | Mechanische Transkatheter-Herzklappenprothese |
| US9937255B2 (en) | 2011-05-18 | 2018-04-10 | Nectero Medical, Inc. | Coated balloons for blood vessel stabilization |
| US8945209B2 (en) | 2011-05-20 | 2015-02-03 | Edwards Lifesciences Corporation | Encapsulated heart valve |
| US10117765B2 (en) | 2011-06-14 | 2018-11-06 | W.L. Gore Associates, Inc | Apposition fiber for use in endoluminal deployment of expandable implants |
| CA2840084C (en) | 2011-06-21 | 2019-11-05 | Foundry Newco Xii, Inc. | Prosthetic heart valve devices and associated systems and methods |
| US10016579B2 (en) | 2011-06-23 | 2018-07-10 | W.L. Gore & Associates, Inc. | Controllable inflation profile balloon cover apparatus |
| US8795357B2 (en) | 2011-07-15 | 2014-08-05 | Edwards Lifesciences Corporation | Perivalvular sealing for transcatheter heart valve |
| US20130023984A1 (en) | 2011-07-20 | 2013-01-24 | Edwards Lifesciences Corporation | Commissure modification of prosthetic heart valve frame for improved leaflet attachment |
| US8852272B2 (en) | 2011-08-05 | 2014-10-07 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
| US20140324164A1 (en) * | 2011-08-05 | 2014-10-30 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
| JP2014530677A (ja) | 2011-09-23 | 2014-11-20 | ゼウス インダストリアル プロダクツ インコーポレイテッド | 複合補綴シャントデバイス |
| US9730726B2 (en) | 2011-10-07 | 2017-08-15 | W. L. Gore & Associates, Inc. | Balloon assemblies having controllably variable topographies |
| US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
| EA201400481A1 (ru) | 2011-10-19 | 2014-10-30 | Твелв, Инк. | Искусственные сердечно-клапанные устройства, искусственные митральные клапаны и соответствующие системы и способы |
| CN104066401B (zh) | 2011-11-16 | 2016-11-09 | 波顿医疗公司 | 用于主动脉分支血管的修复的装置和方法 |
| PL2787926T3 (pl) | 2011-12-09 | 2022-11-14 | Edwards Lifesciences Corporation | Usprawnione wsporniki spojeń zastawki protetycznej serca |
| AU2012358255B2 (en) | 2011-12-23 | 2017-02-16 | Abiomed, Inc. | Heart valve prosthesis with open stent |
| BR112014017472A8 (pt) | 2012-01-16 | 2017-07-04 | Gore & Ass | artigos incluindo membranas de politetrafluoretileno expandido com fibrilas em serpentina e com uma camada de fluoropolímero descontínua nela |
| US20130183515A1 (en) | 2012-01-16 | 2013-07-18 | Charles F. White | Articles including expanded polytetrafluoroethylene membranes with serpentine fibrils |
| US9510935B2 (en) | 2012-01-16 | 2016-12-06 | W. L. Gore & Associates, Inc. | Articles including expanded polytetrafluoroethylene membranes with serpentine fibrils and having a discontinuous fluoropolymer layer thereon |
| EP2809272B1 (en) | 2012-02-01 | 2017-01-04 | Hlt, Inc. | Invertible tissue valve |
| US9375308B2 (en) | 2012-03-13 | 2016-06-28 | W. L. Gore & Associates, Inc. | External steerable fiber for use in endoluminal deployment of expandable devices |
| CN102764169B (zh) | 2012-04-19 | 2015-07-29 | 杭州启明医疗器械有限公司 | 人工心脏瓣膜及其瓣膜支架 |
| CN102652694B (zh) | 2012-05-24 | 2014-06-25 | 上海欣吉特生物科技有限公司 | 人工心脏瓣膜 |
| US9554902B2 (en) | 2012-06-28 | 2017-01-31 | St. Jude Medical, Cardiology Division, Inc. | Leaflet in configuration for function in various shapes and sizes |
| US9283072B2 (en) | 2012-07-25 | 2016-03-15 | W. L. Gore & Associates, Inc. | Everting transcatheter valve and methods |
| US10376360B2 (en) | 2012-07-27 | 2019-08-13 | W. L. Gore & Associates, Inc. | Multi-frame prosthetic valve apparatus and methods |
| EP2712633B1 (de) | 2012-10-02 | 2015-04-29 | Biotronik AG | Bioprosthetische Komponenten für ein Implantat, insbesondere teilvernetzte biologische Herzklappen |
| US20140106951A1 (en) | 2012-10-15 | 2014-04-17 | W. L. Gore & Associates, Inc. | Methods and systems for securing a sleeve for endoluminal devices |
| US9931193B2 (en) | 2012-11-13 | 2018-04-03 | W. L. Gore & Associates, Inc. | Elastic stent graft |
| US10327901B2 (en) | 2012-11-20 | 2019-06-25 | Innovheart S.R.L. | Device for the deployment of a system of guide wires within a cardiac chamber for implanting a prosthetic heart valve |
| EP2931273A1 (en) | 2012-12-12 | 2015-10-21 | The Charlotte-Mecklenburg Hospital Authority D/B/A Carolinas Healthcare System | Methods of treating portal hypertension |
| US10039638B2 (en) | 2012-12-19 | 2018-08-07 | W. L. Gore & Associates, Inc. | Geometric prosthetic heart valves |
| US9968443B2 (en) | 2012-12-19 | 2018-05-15 | W. L. Gore & Associates, Inc. | Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet |
| US10321986B2 (en) | 2012-12-19 | 2019-06-18 | W. L. Gore & Associates, Inc. | Multi-frame prosthetic heart valve |
| US9144492B2 (en) | 2012-12-19 | 2015-09-29 | W. L. Gore & Associates, Inc. | Truncated leaflet for prosthetic heart valves, preformed valve |
| US10279084B2 (en) | 2012-12-19 | 2019-05-07 | W. L. Gore & Associates, Inc. | Medical balloon devices and methods |
| US9398952B2 (en) | 2012-12-19 | 2016-07-26 | W. L. Gore & Associates, Inc. | Planar zone in prosthetic heart valve leaflet |
| EP2745812B1 (en) | 2012-12-19 | 2017-01-18 | Cook Medical Technologies LLC | Repositionable diameter constraints |
| US9737398B2 (en) | 2012-12-19 | 2017-08-22 | W. L. Gore & Associates, Inc. | Prosthetic valves, frames and leaflets and methods thereof |
| US10966820B2 (en) | 2012-12-19 | 2021-04-06 | W. L. Gore & Associates, Inc. | Geometric control of bending character in prosthetic heart valve leaflets |
| US9101469B2 (en) | 2012-12-19 | 2015-08-11 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with leaflet shelving |
| US10654200B2 (en) | 2013-03-07 | 2020-05-19 | S.M. Scienzia Machinale S.R.L. | Apparatus and method for producing a biocompatible three-dimensional object |
| CN105007955B (zh) | 2013-03-13 | 2018-06-22 | W.L.戈尔及同仁股份有限公司 | 适用于植入物的耐用高强度聚合物复合材料及其制品 |
| US9232994B2 (en) | 2013-03-15 | 2016-01-12 | Medtronic Vascular Galway Limited | Stented prosthetic heart valve and methods for making |
| US10905539B2 (en) | 2013-03-15 | 2021-02-02 | W. L. Gore & Associates, Inc. | Self-expanding, balloon expandable stent-grafts |
| JP6397887B2 (ja) | 2013-03-15 | 2018-09-26 | トゥエルヴ, インコーポレイテッド | 人工心臓弁デバイス、人工僧帽弁、ならびに関連システム及び方法 |
| RU2018100991A (ru) | 2013-03-15 | 2019-02-20 | Вэлв Медикал Лтд. | Система и способ уплотнения чрескожного клапана |
| US20140296969A1 (en) | 2013-04-02 | 2014-10-02 | Tendyne Holdlings, Inc. | Anterior Leaflet Clip Device for Prosthetic Mitral Valve |
| GB2513194A (en) | 2013-04-19 | 2014-10-22 | Strait Access Tech Holdings Pty Ltd | A valve |
| WO2014179763A1 (en) | 2013-05-03 | 2014-11-06 | Medtronic Inc. | Valve delivery tool |
| EP3326583B1 (en) | 2013-05-20 | 2018-12-12 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
| EP2999411B1 (en) | 2013-05-23 | 2020-10-07 | Cardiosonic Ltd. | Devices for renal denervation and assessment thereof |
| CN108814772B (zh) | 2013-06-25 | 2020-09-08 | 坦迪尼控股股份有限公司 | 用于假体心脏瓣膜的血栓管理和结构顺应特征 |
| US10524904B2 (en) | 2013-07-11 | 2020-01-07 | Medtronic, Inc. | Valve positioning device |
| US8870948B1 (en) | 2013-07-17 | 2014-10-28 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
| WO2015028209A1 (en) | 2013-08-30 | 2015-03-05 | Jenavalve Technology Gmbh | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
| CA2910602C (en) | 2013-09-20 | 2020-03-10 | Edwards Lifesciences Corporation | Heart valves with increased effective orifice area |
| US10104820B2 (en) | 2013-09-24 | 2018-10-16 | Fuji Corporation | Mounting machine |
| US10226333B2 (en) | 2013-10-15 | 2019-03-12 | Cedars-Sinai Medical Center | Anatomically-orientated and self-positioning transcatheter mitral valve |
| US9622863B2 (en) | 2013-11-22 | 2017-04-18 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
| US10842918B2 (en) | 2013-12-05 | 2020-11-24 | W.L. Gore & Associates, Inc. | Length extensible implantable device and methods for making such devices |
| US9504565B2 (en) | 2013-12-06 | 2016-11-29 | W. L. Gore & Associates, Inc. | Asymmetric opening and closing prosthetic valve leaflet |
| EP3139865B1 (en) | 2014-05-07 | 2025-07-16 | Baylor College of Medicine | Artificial, flexible valves |
| US10231835B2 (en) | 2014-05-16 | 2019-03-19 | Trueleaf Medical Ltd. | Replacement heart valve |
| CA2914094C (en) | 2014-06-20 | 2021-01-05 | Edwards Lifesciences Corporation | Surgical heart valves identifiable post-implant |
| WO2016009337A2 (en) | 2014-07-15 | 2016-01-21 | Koninklijke Philips N.V. | Devices and methods for intrahepatic shunts |
| CN106659567B (zh) | 2014-08-18 | 2019-06-14 | W.L.戈尔及同仁股份有限公司 | 带有用于假体瓣膜的一体缝合封套的框架 |
| US9827094B2 (en) | 2014-09-15 | 2017-11-28 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with retention elements |
| US10507101B2 (en) | 2014-10-13 | 2019-12-17 | W. L. Gore & Associates, Inc. | Valved conduit |
| EP3028668B1 (en) | 2014-12-05 | 2024-10-30 | Nvt Ag | Prosthetic heart valve system and delivery system therefor |
| EP3718510A1 (en) | 2014-12-18 | 2020-10-07 | W. L. Gore & Associates, Inc. | Prosthetic valves with mechanically coupled leaflets |
| US9937037B2 (en) | 2014-12-18 | 2018-04-10 | W. L. Gore & Associates, Inc. | Prosthetic valved conduits with mechanically coupled leaflets |
| US20160235525A1 (en) | 2015-02-12 | 2016-08-18 | Medtronic, Inc. | Integrated valve assembly and method of delivering and deploying an integrated valve assembly |
| US10064718B2 (en) | 2015-04-16 | 2018-09-04 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
| US10441416B2 (en) | 2015-04-21 | 2019-10-15 | Edwards Lifesciences Corporation | Percutaneous mitral valve replacement device |
| WO2016186909A1 (en) | 2015-05-18 | 2016-11-24 | Mayo Foundation For Medical Education And Research | Percutaneously-deployable prosthetic tricuspid valve |
| US10575951B2 (en) | 2015-08-26 | 2020-03-03 | Edwards Lifesciences Cardiaq Llc | Delivery device and methods of use for transapical delivery of replacement mitral valve |
| JP6470150B2 (ja) | 2015-09-03 | 2019-02-13 | 日本ライフライン株式会社 | ステントおよび医療機器 |
| US9789294B2 (en) | 2015-10-07 | 2017-10-17 | Edwards Lifesciences Corporation | Expandable cardiac shunt |
| US10456243B2 (en) | 2015-10-09 | 2019-10-29 | Medtronic Vascular, Inc. | Heart valves prostheses and methods for percutaneous heart valve replacement |
| US10004617B2 (en) | 2015-10-20 | 2018-06-26 | Cook Medical Technologies Llc | Woven stent device and manufacturing method |
| US10470876B2 (en) | 2015-11-10 | 2019-11-12 | Edwards Lifesciences Corporation | Transcatheter heart valve for replacing natural mitral valve |
| US10583007B2 (en) | 2015-12-02 | 2020-03-10 | Edwards Lifesciences Corporation | Suture deployment of prosthetic heart valve |
| EP3632380B1 (en) | 2015-12-03 | 2024-01-24 | Tendyne Holdings, Inc. | Frame features for prosthetic mitral valves |
| US9931204B2 (en) | 2015-12-10 | 2018-04-03 | Medtronic, Inc. | Transcatheter heart valve replacement systems, heart valve prostheses, and methods for percutaneous heart valve replacement |
| EP3389566B1 (en) | 2015-12-14 | 2024-05-08 | Medtronic Vascular, Inc. | Devices for transcatheter valve loading and implantation |
| EP4652972A3 (en) | 2016-04-21 | 2026-01-14 | W. L. Gore & Associates, Inc. | Diametrically adjustable endoprostheses and associated systems and methods |
| US10758350B2 (en) | 2016-06-06 | 2020-09-01 | Medtronic Vascular, Inc. | Transcatheter prosthetic heart valve delivery system with protective feature |
| US10350062B2 (en) | 2016-07-21 | 2019-07-16 | Edwards Lifesciences Corporation | Replacement heart valve prosthesis |
| CA3051272C (en) | 2017-01-23 | 2023-08-22 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
| CN111182856B (zh) | 2017-09-12 | 2022-04-29 | W.L.戈尔及同仁股份有限公司 | 用于假体瓣膜的瓣叶框架附连件 |
| CN111132636B (zh) | 2017-09-27 | 2022-04-08 | W.L.戈尔及同仁股份有限公司 | 带有可扩张框架的假体瓣膜以及相关系统和方法 |
| CN111163728B (zh) | 2017-09-27 | 2022-04-29 | W.L.戈尔及同仁股份有限公司 | 具有机械联接的瓣叶的假体瓣膜 |
| US12357446B2 (en) | 2017-10-09 | 2025-07-15 | W. L. Gore & Associates, Inc. | Matched stent cover |
| US11090153B2 (en) | 2017-10-13 | 2021-08-17 | W. L. Gore & Associates, Inc. | Telescoping prosthetic valve and delivery system |
| US11154397B2 (en) | 2017-10-31 | 2021-10-26 | W. L. Gore & Associates, Inc. | Jacket for surgical heart valve |
| EP3703615B1 (en) | 2017-10-31 | 2024-05-15 | W. L. Gore & Associates, Inc. | Transcatheter deployment systems and associated methods |
| US11123183B2 (en) | 2017-10-31 | 2021-09-21 | W. L. Gore & Associates, Inc. | Prosthetic heart valve |
| US11439502B2 (en) | 2017-10-31 | 2022-09-13 | W. L. Gore & Associates, Inc. | Medical valve and leaflet promoting tissue ingrowth |
| CN108578016B (zh) | 2018-04-26 | 2020-09-08 | 赛诺医疗科学技术股份有限公司 | 一种经心尖植入式二尖瓣瓣膜装置 |
| US20210259831A1 (en) | 2018-06-20 | 2021-08-26 | W. L. Gore & Associates, Inc. | Support structure for an implantable device with enhanced compressive stiffness region(s) |
| USD926322S1 (en) | 2018-11-07 | 2021-07-27 | W. L. Gore & Associates, Inc. | Heart valve cover |
| US20200179663A1 (en) | 2018-12-11 | 2020-06-11 | W. L. Gore & Associates, Inc. | Medical devices for shunts, occluders, fenestrations and related systems and methods |
| US11497601B2 (en) | 2019-03-01 | 2022-11-15 | W. L. Gore & Associates, Inc. | Telescoping prosthetic valve with retention element |
| JP7381601B2 (ja) | 2019-04-12 | 2023-11-15 | エドワーズ ライフサイエンシーズ コーポレイション | マルチパートフレーム及び関連するレジリエントブリッジ特徴部を備えた弁 |
| WO2021022211A1 (en) | 2019-08-01 | 2021-02-04 | W. L. Gore & Associates, Inc. | Transcatheter prosthetic valve with multi-part frame subcomponent transverse deformation resistance |
-
2013
- 2013-03-12 US US13/797,633 patent/US9283072B2/en active Active
- 2013-06-18 EP EP18204192.1A patent/EP3501454B1/en active Active
- 2013-06-18 EP EP17167842.8A patent/EP3216424B1/en active Active
- 2013-06-18 CN CN201611145583.2A patent/CN106726007B/zh active Active
- 2013-06-18 AU AU2013293455A patent/AU2013293455B2/en active Active
- 2013-06-18 CA CA3098032A patent/CA3098032C/en active Active
- 2013-06-18 JP JP2015524278A patent/JP6382808B2/ja active Active
- 2013-06-18 RU RU2015106127A patent/RU2015106127A/ru unknown
- 2013-06-18 KR KR1020157004610A patent/KR102151603B1/ko active Active
- 2013-06-18 CA CA3189972A patent/CA3189972A1/en active Pending
- 2013-06-18 CN CN201380039305.7A patent/CN104487023B/zh active Active
- 2013-06-18 CA CA3020935A patent/CA3020935C/en active Active
- 2013-06-18 ES ES18204192T patent/ES2823223T3/es active Active
- 2013-06-18 CA CA2963234A patent/CA2963234C/en active Active
- 2013-06-18 WO PCT/US2013/046389 patent/WO2014018189A2/en not_active Ceased
- 2013-06-18 EP EP15186981.5A patent/EP3001979B1/en active Active
- 2013-06-18 CN CN201811169010.2A patent/CN109363803B/zh active Active
- 2013-06-18 EP EP13735108.6A patent/EP2877122B1/en active Active
- 2013-06-18 KR KR1020207024692A patent/KR20200104930A/ko not_active Ceased
- 2013-06-18 CA CA2878180A patent/CA2878180C/en active Active
- 2013-06-18 BR BR112015001626A patent/BR112015001626A2/pt not_active IP Right Cessation
- 2013-06-18 EP EP20179778.4A patent/EP3733131B1/en active Active
-
2016
- 2016-02-12 US US15/042,351 patent/US10285808B2/en active Active
- 2016-12-14 AU AU2016273906A patent/AU2016273906B2/en active Active
-
2018
- 2018-07-31 JP JP2018143521A patent/JP6959195B2/ja active Active
-
2019
- 2019-03-20 US US16/359,650 patent/US11166809B2/en active Active
- 2019-08-15 AU AU2019216680A patent/AU2019216680A1/en not_active Abandoned
-
2020
- 2020-04-09 JP JP2020070179A patent/JP7237039B2/ja active Active
-
2021
- 2021-10-06 US US17/495,042 patent/US11950999B2/en active Active
-
2022
- 2022-01-21 JP JP2022007912A patent/JP2022058718A/ja active Pending
-
2024
- 2024-01-17 JP JP2024005237A patent/JP2024026812A/ja not_active Ceased
- 2024-02-23 US US18/585,786 patent/US20240238081A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2823223T3 (es) | Válvula transcatéter de eversión | |
| ES2859759T3 (es) | Aparato de válvula protésica de múltiples estructuras y método de fabricación | |
| ES2715786T3 (es) | Valva truncada para válvulas protésicas de corazón | |
| ES2640637T3 (es) | Control geométrico de característica de curvatura en las valvas de válvula cardíaca protésica | |
| HK40008980A (en) | Everting transcatheter valve | |
| HK1242552A1 (en) | Everting transcatheter valve | |
| HK1242552B (en) | Everting transcatheter valve | |
| HK1216603B (en) | Method of making a transcatheter valve | |
| HK1205918B (en) | Everting transcatheter valve |