ES2738289T3 - Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión - Google Patents

Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión Download PDF

Info

Publication number
ES2738289T3
ES2738289T3 ES14803288T ES14803288T ES2738289T3 ES 2738289 T3 ES2738289 T3 ES 2738289T3 ES 14803288 T ES14803288 T ES 14803288T ES 14803288 T ES14803288 T ES 14803288T ES 2738289 T3 ES2738289 T3 ES 2738289T3
Authority
ES
Spain
Prior art keywords
gene expression
genbank accession
probes
subject
genbank
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14803288T
Other languages
English (en)
Spanish (es)
Inventor
Louis M Staudt
George W Wright
David William Scott
Joseph M Connors
Randy D Gascoyne
Lisa Rimsza
Guerri Elias Campo
Timothy C Greiner
James Robert Cook
Kai Fu
Paul Michael Williams
Chih-Jian Lih
Elaine S Jaffe
Rita M Braziel
Andreas Rosenwald
Erlend B Smeland
Wing C Chan
German Ott
Jan Delabie
Dennis Weisenburger
Raymond Tubbs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
British Columbia Cancer Agency BCCA
Julius Maximilians Universitaet Wuerzburg
Universitat de Barcelona UB
Hospital Clinic de Barcelona
Oslo Universitetssykehus hf
Oregon Health and Science University
University of Nebraska Lincoln
Cleveland Clinic
University of Arizona
University of Nebraska System
US Department of Health and Human Services
Original Assignee
British Columbia Cancer Agency BCCA
Julius Maximilians Universitaet Wuerzburg
Universitat de Barcelona UB
Hospital Clinic de Barcelona
Oslo Universitetssykehus hf
Oregon Health and Science University
University of Nebraska Lincoln
Cleveland Clinic
University of Arizona
University of Nebraska System
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Columbia Cancer Agency BCCA, Julius Maximilians Universitaet Wuerzburg, Universitat de Barcelona UB, Hospital Clinic de Barcelona, Oslo Universitetssykehus hf, Oregon Health and Science University, University of Nebraska Lincoln, Cleveland Clinic, University of Arizona, University of Nebraska System, US Department of Health and Human Services filed Critical British Columbia Cancer Agency BCCA
Application granted granted Critical
Publication of ES2738289T3 publication Critical patent/ES2738289T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/166Oligonucleotides used as internal standards, controls or normalisation probes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Physiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES14803288T 2013-11-06 2014-11-05 Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión Active ES2738289T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361900553P 2013-11-06 2013-11-06
PCT/US2014/064161 WO2015069790A1 (en) 2013-11-06 2014-11-05 Method for subtyping lymphoma types by means expression profiling

Publications (1)

Publication Number Publication Date
ES2738289T3 true ES2738289T3 (es) 2020-01-21

Family

ID=51987470

Family Applications (2)

Application Number Title Priority Date Filing Date
ES14803288T Active ES2738289T3 (es) 2013-11-06 2014-11-05 Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión
ES19170689T Active ES2923942T3 (es) 2013-11-06 2014-11-05 Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES19170689T Active ES2923942T3 (es) 2013-11-06 2014-11-05 Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión

Country Status (9)

Country Link
US (2) US10607717B2 (https=)
EP (2) EP3594359B1 (https=)
JP (2) JP6657105B2 (https=)
KR (1) KR102357699B1 (https=)
CN (1) CN106232831B (https=)
AU (1) AU2014346788B8 (https=)
CA (1) CA2929826C (https=)
ES (2) ES2738289T3 (https=)
WO (1) WO2015069790A1 (https=)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX383691B (es) 2015-03-06 2025-03-14 Beyondspring Pharmaceuticals Inc Método de tratamiento de cáncer asociado con una mutación de ras.
US20240430385A1 (en) * 2015-04-16 2024-12-26 Offender Smartphone Monitoring, LLC Monitoring process
WO2016168667A1 (en) * 2015-04-16 2016-10-20 Offender Smartphone Monitoring, LLC Monitoring process
US10155748B2 (en) 2015-07-13 2018-12-18 Beyondspring Pharmaceuticals, Inc. Plinabulin compositions
CN108368554B (zh) * 2015-09-29 2022-09-09 Htg分子诊断有限公司 弥漫性大b细胞淋巴瘤(dlbcl)亚型分型的方法
WO2017139231A1 (en) 2016-02-08 2017-08-17 Beyondspring Pharmaceuticals, Inc. Compositions containing tucaresol or its analogs
JP7075896B2 (ja) * 2016-04-20 2022-05-26 アメリカ合衆国 マントル細胞リンパ腫の評価及びそれに関連する方法
US9963748B2 (en) 2016-05-13 2018-05-08 Roche Molecular Systems, Inc. Methods and compositions for classifying DLBCL
RU2760348C2 (ru) 2016-06-06 2021-11-24 Бейондспринг Фармасьютикалс, Инк. Способ уменьшения нейтропении
US11696250B2 (en) * 2016-11-09 2023-07-04 Intel Corporation UE and devices for detach handling
JP2020503363A (ja) 2017-01-06 2020-01-30 ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド チューブリン結合化合物およびその治療的使用
BR112019015974A2 (pt) 2017-02-01 2020-03-31 Beyondspring Pharmaceuticals, Inc. Método para reduzir neutropenia
EP3638814B8 (en) 2017-06-14 2023-06-21 The United States of America, as Represented by The Secretary, Department of Health and Human Services Method for determining lymphoma type
ES2933256T3 (es) * 2017-08-08 2023-02-03 Hoffmann La Roche Tratamiento con obinutuzumab de un subgrupo de pacientes con LDLBG
JP7517983B2 (ja) * 2017-11-20 2024-07-17 ユリウス-マクシミリアン-ウニヴェルシテート・ヴュルツブルク 非常に低レベルのcd19を発現する骨髄腫細胞を除去するcd19cart細胞
CN110945130B (zh) 2017-12-01 2024-04-09 苏州瑞博生物技术股份有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
JP7365052B2 (ja) 2017-12-01 2023-10-19 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、当該核酸を含む組成物及び複合体ならびに調製方法と使用
CA3083968C (en) 2017-12-01 2024-04-23 Suzhou Ribo Life Science Co., Ltd. Double-stranded oligonucleotide, composition and conjugate comprising double-stranded oligonucleotide, preparation method thereof and use thereof
WO2019105437A1 (zh) 2017-12-01 2019-06-06 苏州瑞博生物技术有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
WO2019105435A1 (zh) 2017-12-01 2019-06-06 苏州瑞博生物技术有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
EP3732185B1 (en) 2017-12-29 2025-02-26 Suzhou Ribo Life Science Co., Ltd. Conjugates and preparation and use thereof
KR20200112881A (ko) 2018-01-24 2020-10-05 비욘드스프링 파마수티컬스, 인코포레이티드. 플리나불린의 투여를 통해 혈소판감소증을 감소시키는 조성물 및 방법
WO2020028563A1 (en) * 2018-08-01 2020-02-06 Genentech, Inc. Prediction and characterization of dlbcl cell of origin subtypes
US11918600B2 (en) 2018-08-21 2024-03-05 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition and conjugate containing nucleic acid, and use thereof
EP3862024A4 (en) 2018-09-30 2022-08-17 Suzhou Ribo Life Science Co., Ltd. SIRNA CONJUGATE, METHOD FOR ITS PRODUCTION AND ITS USE
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
WO2020079591A1 (en) * 2018-10-15 2020-04-23 Provincial Health Services Authority Gene expression profiles for b-cell lymphoma and uses thereof
MX2021005646A (es) * 2018-11-14 2021-08-11 Beyondspring Pharmaceuticals Inc Métodos de tratamiento de cáncer con agentes de unión a tubulina.
US12496347B2 (en) 2018-12-28 2025-12-16 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, composition and conjugate containing nucleic acid, preparation method therefor and use thereof
AU2020245086B2 (en) * 2019-03-28 2026-01-08 Centre Henri Becquerel Classification of B-Cell non-Hodgkin Lymphomas
CN111850114A (zh) * 2019-04-25 2020-10-30 上海交通大学医学院附属瑞金医院 一组用于评估弥漫大b细胞淋巴瘤分子分型的基因群,其试剂盒及分析方法
WO2020233651A1 (zh) * 2019-05-22 2020-11-26 苏州瑞博生物技术股份有限公司 核酸、药物组合物与缀合物及制备方法和用途
JP7610268B2 (ja) 2019-05-22 2025-01-08 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、薬物組成物及び複合体ならびに調製方法と使用
WO2020233680A1 (zh) 2019-05-22 2020-11-26 苏州瑞博生物技术股份有限公司 核酸、药物组合物与缀合物及制备方法和用途
AU2020280438B2 (en) 2019-05-22 2025-03-06 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
EP3978609A4 (en) 2019-05-24 2024-02-07 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
EP4682889A3 (en) * 2019-07-22 2026-04-15 F. Hoffmann-La Roche AG Systems and methods for cell of origin determination from variant calling data
MX2022001812A (es) 2019-08-12 2022-03-11 Regeneron Pharma Variantes del receptor estimulante de macrofagos 1 (mst1r) y sus usos.
CN111621565B (zh) * 2020-05-07 2023-12-15 杭州可帮基因科技有限公司 弥漫性大b细胞淋巴瘤分子分型试剂盒及分型装置
CN111785370B (zh) * 2020-07-01 2024-05-17 医渡云(北京)技术有限公司 病历数据处理方法及装置、计算机存储介质、电子设备
CN115955962B (zh) * 2020-07-08 2024-07-12 代顿治疗股份公司 用于治疗淋巴肿瘤的沙铂
JP2023536900A (ja) * 2020-08-05 2023-08-30 ティアークリアー コープ. 眼科用製剤からの防腐剤除去のためのシステムおよび方法
CA3215047A1 (en) 2021-04-09 2022-10-13 Lan Huang Therapeutic compositions and methods for treating tumors
CN113186289B (zh) * 2021-05-12 2023-02-24 清华大学深圳国际研究生院 lncRNA在肾癌尿液筛查和肾癌治疗中的应用
CN119842823A (zh) * 2024-12-25 2025-04-18 南方医科大学皮肤病医院(广东省皮肤病医院、广东省皮肤性病防治中心、中国麻风防治研究中心) SLC35E2B在Hacat细胞模型构建中的应用

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5242974A (en) 1991-11-22 1993-09-07 Affymax Technologies N.V. Polymer reversal on solid surfaces
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5527681A (en) 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
US5252743A (en) 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
DE69132905T2 (de) 1990-12-06 2002-08-01 Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) Detektion von Nukleinsäuresequenzen
JP2001524926A (ja) 1991-09-18 2001-12-04 アフィマックス テクノロジーズ ナームロゼ フェンノートシャップ オリゴマーの雑多ライブラリーの集合体を合成する方法
US5550215A (en) 1991-11-22 1996-08-27 Holmes; Christopher P. Polymer reversal on solid surfaces
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
DE69233501T2 (de) 1991-11-22 2006-02-23 Affymetrix, Inc. (n.d.Ges.d.Staates Delaware), Santa Clara Kombinatorische Strategien für die Polymersynthese
US5324633A (en) 1991-11-22 1994-06-28 Affymax Technologies N.V. Method and apparatus for measuring binding affinity
US5491074A (en) 1993-04-01 1996-02-13 Affymax Technologies Nv Association peptides
US5858659A (en) 1995-11-29 1999-01-12 Affymetrix, Inc. Polymorphism detection
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
US6090555A (en) 1997-12-11 2000-07-18 Affymetrix, Inc. Scanned image alignment systems and methods
US5578832A (en) 1994-09-02 1996-11-26 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
US5631734A (en) 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
WO1995030774A1 (en) 1994-05-05 1995-11-16 Beckman Instruments, Inc. Oligonucleotide repeat arrays
US5571639A (en) 1994-05-24 1996-11-05 Affymax Technologies N.V. Computer-aided engineering system for design of sequence arrays and lithographic masks
US5795716A (en) 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
US5599695A (en) 1995-02-27 1997-02-04 Affymetrix, Inc. Printing molecular library arrays using deprotection agents solely in the vapor phase
US5624711A (en) 1995-04-27 1997-04-29 Affymax Technologies, N.V. Derivatization of solid supports and methods for oligomer synthesis
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5968740A (en) 1995-07-24 1999-10-19 Affymetrix, Inc. Method of Identifying a Base in a Nucleic Acid
WO1997043611A1 (en) 1996-05-16 1997-11-20 Affymetrix, Inc. Systems and methods for detection of labeled materials
EP1027456B1 (en) 1997-10-31 2005-03-16 Affymetrix, Inc. (a Delaware Corporation) Expression profiles in adult and fetal organs
US5936324A (en) 1998-03-30 1999-08-10 Genetic Microsystems Inc. Moving magnet scanner
US6020198A (en) 1998-09-25 2000-02-01 Isis Pharmaceuticals Inc. Antisense modulation of RIP-1 expression
US7105293B2 (en) 2000-09-19 2006-09-12 Whitehead Institute For Biomedical Research Genetic markers for tumors
US20030194701A1 (en) 2000-11-20 2003-10-16 Golub Todd R. Diffuse large cell lymphoma diagnosis and outcome prediction by expression analysis
US7473767B2 (en) 2001-07-03 2009-01-06 The Institute For Systems Biology Methods for detection and quantification of analytes in complex mixtures
US7622260B2 (en) 2001-09-05 2009-11-24 The Brigham And Women's Hospital, Inc. Diagnostic and prognostic tests
CN1273465C (zh) 2001-09-21 2006-09-06 保宁制药株式会社 嘧啶酮化合物及其药学上可接受的盐的制备方法
US7371736B2 (en) 2001-11-07 2008-05-13 The Board Of Trustees Of The University Of Arkansas Gene expression profiling based identification of DKK1 as a potential therapeutic targets for controlling bone loss
ES2542328T3 (es) 2002-12-06 2015-08-04 Millennium Pharmaceuticals, Inc. Métodos para la identificación, evaluación y tratamiento de pacientes con terapia de inhibición del proteasoma
NZ585188A (en) 2003-08-15 2011-09-30 Novartis Ag 2,4-Pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders
US20110152115A1 (en) 2003-09-03 2011-06-23 The United States of America, as represented by the Secretary, Department of Health and Methods for identifying, diagnosing, and predicting survival of lymphomas
US8131475B2 (en) * 2003-09-03 2012-03-06 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Methods for identifying, diagnosing, and predicting survival of lymphomas
EP2157524A3 (en) 2003-09-03 2010-12-08 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Methods for identifying, diagnosing, and predicting survival of lymphomas
ATE514434T1 (de) 2004-02-25 2011-07-15 Dana Farber Cancer Inst Inc Hemmer des insulinartigen wachstumsfaktor- rezeptors-1 zur hemmung von tumorzellwachstum
EP1805197A1 (en) 2004-09-27 2007-07-11 Med Biogene Inc Hematological cancer profiling system
US8349555B2 (en) 2005-03-16 2013-01-08 Gennadi V. Glinsky Methods and compositions for predicting death from cancer and prostate cancer survival using gene expression signatures
MX2010005080A (es) * 2007-11-07 2010-07-28 Genentech Inc Metodos y composiciones para determinar la sensibilidad de linfoma de celula b al tratamiento con anticuerpos anti-cd40.
EP2245199B1 (en) * 2008-02-01 2013-11-13 The General Hospital Corporation Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditions
US20110195064A1 (en) 2008-06-06 2011-08-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv Survival predictor for diffuse large b cell lymphoma
BR112012001077A2 (pt) 2009-07-16 2020-08-11 The General Hospital Corporation extração de ácido nucleico, métodos para avaliar a qualidade de uma extração de ácido nucleico e de uma amostra biológica, para ober ácido nucleico a partir de uma amostra biológica, para analisar rna de microvesículas e para diagnosticar e monitorar um indivíduo, e, kit
ES2352777B1 (es) 2009-07-31 2012-01-23 Hospital Clinic De Barcelona Metodo y kit para el pronostico del linfoma de celulas del manto
WO2011060272A2 (en) * 2009-11-13 2011-05-19 Dana-Farber Cancer Institute, Inc. Compositions, kits, and methods for the diagnosis, prognosis, monitoring, treatment and modulation of post-transplant lymphoproliferative disorders and hypoxia associated angiogenesis disorders using galectin-1
WO2011097476A1 (en) * 2010-02-04 2011-08-11 Indiana University Research And Technology Corporation 4-protein biomarker panel for the diagnosis of lymphoma from biospecimen
EP2569335B1 (en) * 2010-05-14 2018-08-22 Orega Biotech Methods of treating and/or preventing cell proliferation disorders with il-17 antagonists
CN107898791A (zh) * 2010-06-03 2018-04-13 药品循环有限责任公司 布鲁顿酪氨酸激酶(btk)抑制剂的应用
US20120258878A1 (en) 2010-08-04 2012-10-11 Med Biogene Inc. Prognostic gene signatures for non-small cell lung cancer
CA2834535A1 (en) 2011-04-29 2012-11-01 Celgene Corporation Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor
CA2858383A1 (en) 2011-12-09 2013-06-13 British Columbia Cancer Agency Branch Predicting prognosis in classic hodgkin lymphoma
JP2015509489A (ja) 2012-02-10 2015-03-30 ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ がんの処置のためのグリシン開裂系の阻害
US9803245B2 (en) 2012-03-14 2017-10-31 University Health Network Signature for predicting clinical outcome in human HER2+ breast cancer
WO2013188600A1 (en) 2012-06-12 2013-12-19 Washington University Copy number aberration driven endocrine response gene signature
WO2014197936A1 (en) 2013-06-14 2014-12-18 The State Of Queensland Acting Through Its Department Of Health Biomarkers and use thereof in identification of b-cell lymphoproliferative disorders
IL278381B2 (en) 2013-12-06 2024-08-01 Celgene Corp Methods for determining the effectiveness of a drug for the treatment of diffuse large B-cell lymphoma, multiple myeloma, and myeloid cancer
KR20170068504A (ko) 2014-10-08 2017-06-19 노파르티스 아게 키메라 항원 수용체 요법에 대한 치료 반응성을 예측하는 바이오마커 및 그의 용도

Also Published As

Publication number Publication date
EP3594359A1 (en) 2020-01-15
EP3066215A1 (en) 2016-09-14
JP7016129B2 (ja) 2022-02-04
ES2923942T3 (es) 2022-10-03
KR20160127713A (ko) 2016-11-04
AU2014346788B2 (en) 2020-09-24
EP3066215B1 (en) 2019-04-24
US20200143906A1 (en) 2020-05-07
WO2015069790A1 (en) 2015-05-14
JP6657105B2 (ja) 2020-03-04
CA2929826C (en) 2022-08-16
CN106232831B (zh) 2021-02-26
US10607717B2 (en) 2020-03-31
AU2014346788B8 (en) 2021-01-28
EP3594359B1 (en) 2022-05-18
KR102357699B1 (ko) 2022-02-04
WO2015069790A9 (en) 2016-06-02
JP2020078323A (ja) 2020-05-28
US11574704B2 (en) 2023-02-07
JP2017502686A (ja) 2017-01-26
AU2014346788A8 (en) 2016-06-16
CN106232831A (zh) 2016-12-14
US20160283653A1 (en) 2016-09-29
CA2929826A1 (en) 2015-05-14
AU2014346788A1 (en) 2016-05-26

Similar Documents

Publication Publication Date Title
ES2738289T3 (es) Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión
US10697975B2 (en) Methods for identifying, diagnosing, and predicting survival of lymphomas
US8202968B2 (en) Predicting lung cancer survival using gene expression
ES2339132T3 (es) Metodos y kit para el pronostico de cancer de mama.
EP2971177B1 (en) Compositions and methods for detecting and determining a prognosis for prostate cancer
JP4435259B2 (ja) 微量胃癌細胞の検出法
WO2013052480A1 (en) Marker-based prognostic risk score in colon cancer
CN104031915A (zh) 用于结直肠癌预后的基因片段及其应用
CN104046624A (zh) 用于肺癌预后的基因及其应用
US20140371081A1 (en) Compositions for and Methods of Detecting, Diagnosing, and Prognosing Thymic Cancer
Miao et al. The association between fibroblast growth factor receptor 1 gene amplification and lung cancer: a meta-analysis
US10519507B2 (en) Method for detecting T-cell lymphoma
US10174382B2 (en) Breast cancer prognostication and screening kits and methods of using same
EP3931570A1 (en) High-grade serous ovarian carcinoma (hgsoc)
CN105506169B (zh) 子宫肌瘤诊治标志物
CA3212786A1 (en) Methods for assessing proliferation and anti-folate therapeutic response
KR102856145B1 (ko) 말초 t세포 림프종 예후 예측용 신규 바이오마커 및 이의 용도
KR102615451B1 (ko) Her2 양성 유방암 치료 예후 예측용 신규 바이오마커 및 이의 용도
EP2708606A1 (en) Novel biomarkers for human cervical cancer and/or HPV infection
AU2007277142B2 (en) Methods for identifying, diagnosing, and predicting survival of lymphomas
ES2745718T3 (es) Método para apoyar el diagnóstico de riesgo de recurrencia de un cáncer colorrectal, programa y sistema de computadora
HK1228459A1 (en) Method for subtyping lymphoma types by means of expression profiling
HK1228459B (en) Method for subtyping lymphoma types by means of expression profiling
KR20040025185A (ko) 사이토카인 유전자 발현분석을 이용하여 방사선 치료에대한 암환자의 반응을 평가하는 방법 및 이를 위한 dna칩
KR20040025184A (ko) Hsp 유전자 발현분석을 이용하여 방사선 치료에 대한암환자의 반응을 평가하는 방법 및 이를 위한 DNA 칩