ES2694297T3 - Formas cristalinas de ácido {[1-ciano-5-(4-clorofenoxi)-4-hidroxi-isoquinolina-3-carbonilo]-amino}-acético - Google Patents
Formas cristalinas de ácido {[1-ciano-5-(4-clorofenoxi)-4-hidroxi-isoquinolina-3-carbonilo]-amino}-acético Download PDFInfo
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- ES2694297T3 ES2694297T3 ES14704030.7T ES14704030T ES2694297T3 ES 2694297 T3 ES2694297 T3 ES 2694297T3 ES 14704030 T ES14704030 T ES 14704030T ES 2694297 T3 ES2694297 T3 ES 2694297T3
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361756361P | 2013-01-24 | 2013-01-24 | |
| US201361756361P | 2013-01-24 | ||
| PCT/US2014/012780 WO2014116849A1 (en) | 2013-01-24 | 2014-01-23 | Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2694297T3 true ES2694297T3 (es) | 2018-12-19 |
Family
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Family Applications (1)
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| EP (1) | EP2951159B1 (enExample) |
| JP (1) | JP6437456B2 (enExample) |
| KR (1) | KR102233081B1 (enExample) |
| CN (1) | CN105452227B (enExample) |
| AU (1) | AU2014209319B2 (enExample) |
| CA (1) | CA2899024C (enExample) |
| DK (1) | DK2951159T3 (enExample) |
| ES (1) | ES2694297T3 (enExample) |
| IL (1) | IL240066B (enExample) |
| MX (1) | MX360048B (enExample) |
| RU (1) | RU2666144C2 (enExample) |
| SG (2) | SG11201505748UA (enExample) |
| TW (1) | TWI685487B (enExample) |
| WO (1) | WO2014116849A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1644336T3 (pl) | 2003-06-06 | 2011-07-29 | Fibrogen Inc | Związki heteroarylowe zawierające azot i ich zastosowanie w zwiększaniu poziomu endogennej erytropoetyny |
| EP2370422B1 (en) | 2008-11-14 | 2019-06-05 | Fibrogen, Inc. | Thiochromene derivatives as hif hydroxylase inhibitors |
| US8883823B2 (en) | 2012-07-16 | 2014-11-11 | Fibrogen, Inc. | Crystalline forms of a prolyl hydroxylase inhibitor |
| SG10201700873UA (en) | 2012-07-16 | 2017-04-27 | Fibrogen Inc | Crystalline forms of the prolyl hydroxylase inhibitor [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid |
| CA2879238C (en) | 2012-07-16 | 2021-08-10 | Fibrogen, Inc. | Process for making isoquinoline compounds |
| JP6437456B2 (ja) | 2013-01-24 | 2018-12-12 | フィブロジェン インコーポレイテッド | ｛［１−シアノ−５−（４−クロロフェノキシ）−４−ヒドロキシ−イソキノリン−３−カルボニル］−アミノ｝−酢酸の結晶形態 |
| CN110448537A (zh) | 2013-06-06 | 2019-11-15 | 菲布罗根有限公司 | Hif羟化酶抑制剂的药物制剂 |
| WO2016034108A1 (zh) | 2014-09-02 | 2016-03-10 | 广东东阳光药业有限公司 | 喹啉酮类化合物及其应用 |
| EP4121009A4 (en) * | 2020-03-17 | 2024-04-17 | Zydus Lifesciences Limited | Formulation comprising hif prolyl hydroxylase inhibitors |
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2014
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- 2014-01-23 TW TW103102462A patent/TWI685487B/zh not_active IP Right Cessation
- 2014-01-23 SG SG11201505748UA patent/SG11201505748UA/en unknown
- 2014-01-23 SG SG10202009266PA patent/SG10202009266PA/en unknown
- 2014-01-23 DK DK14704030.7T patent/DK2951159T3/en active
- 2014-01-23 WO PCT/US2014/012780 patent/WO2014116849A1/en not_active Ceased
- 2014-01-23 KR KR1020157022614A patent/KR102233081B1/ko active Active
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- 2014-01-23 CN CN201480016402.9A patent/CN105452227B/zh active Active
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2015
- 2015-07-21 IL IL240066A patent/IL240066B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX360048B (es) | 2018-10-19 |
| CN105452227B (zh) | 2018-05-29 |
| HK1217331A1 (en) | 2017-01-06 |
| SG11201505748UA (en) | 2015-08-28 |
| IL240066A0 (en) | 2015-09-24 |
| IL240066B (en) | 2019-08-29 |
| KR20150129679A (ko) | 2015-11-20 |
| JP2016505071A (ja) | 2016-02-18 |
| AU2014209319A1 (en) | 2015-08-27 |
| US9643928B2 (en) | 2017-05-09 |
| WO2014116849A1 (en) | 2014-07-31 |
| KR102233081B1 (ko) | 2021-03-29 |
| AU2014209319B2 (en) | 2018-04-19 |
| TWI685487B (zh) | 2020-02-21 |
| CA2899024A1 (en) | 2014-07-31 |
| EP2951159B1 (en) | 2018-08-22 |
| RU2015134420A (ru) | 2017-03-03 |
| TW201444800A (zh) | 2014-12-01 |
| SG10202009266PA (en) | 2020-10-29 |
| CN105452227A (zh) | 2016-03-30 |
| EP2951159A1 (en) | 2015-12-09 |
| RU2666144C2 (ru) | 2018-09-06 |
| JP6437456B2 (ja) | 2018-12-12 |
| MX2015009617A (es) | 2016-04-20 |
| CA2899024C (en) | 2022-01-04 |
| DK2951159T3 (en) | 2018-11-19 |
| US20160002170A1 (en) | 2016-01-07 |
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