MX360048B - Formas cristalinas de acido { [1-ciano-5-(4-clorofenoxi)-4-hidroxi -isoquinolin-3-carbonil]-amino}-acetico. - Google Patents

Formas cristalinas de acido { [1-ciano-5-(4-clorofenoxi)-4-hidroxi -isoquinolin-3-carbonil]-amino}-acetico.

Info

Publication number
MX360048B
MX360048B MX2015009617A MX2015009617A MX360048B MX 360048 B MX360048 B MX 360048B MX 2015009617 A MX2015009617 A MX 2015009617A MX 2015009617 A MX2015009617 A MX 2015009617A MX 360048 B MX360048 B MX 360048B
Authority
MX
Mexico
Prior art keywords
crystalline forms
chlorophenoxy
cyano
carbonyl
hydroxy
Prior art date
Application number
MX2015009617A
Other languages
English (en)
Other versions
MX2015009617A (es
Inventor
Witschi Claudia
P Arend Michael
Min Park Jung
D Thompson Michael
Original Assignee
Fibrogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50073508&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX360048(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fibrogen Inc filed Critical Fibrogen Inc
Publication of MX2015009617A publication Critical patent/MX2015009617A/es
Publication of MX360048B publication Critical patent/MX360048B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente descripción se refiere a formas cristalinas de ácido {[1-ciano-5-(4-clorofenoxi)-4-hidrox-soquinoIin-3-carbonil]-amino }- acético (Compuesto A), el proceso para preparar formas cristalinas de Compuesto A, las composiciones farmacéuticas que las contienen y los métodos de uso de las mismas.
MX2015009617A 2013-01-24 2014-01-23 Formas cristalinas de acido { [1-ciano-5-(4-clorofenoxi)-4-hidroxi -isoquinolin-3-carbonil]-amino}-acetico. MX360048B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361756361P 2013-01-24 2013-01-24
PCT/US2014/012780 WO2014116849A1 (en) 2013-01-24 2014-01-23 Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid

Publications (2)

Publication Number Publication Date
MX2015009617A MX2015009617A (es) 2016-04-20
MX360048B true MX360048B (es) 2018-10-19

Family

ID=50073508

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015009617A MX360048B (es) 2013-01-24 2014-01-23 Formas cristalinas de acido { [1-ciano-5-(4-clorofenoxi)-4-hidroxi -isoquinolin-3-carbonil]-amino}-acetico.

Country Status (15)

Country Link
US (1) US9643928B2 (es)
EP (1) EP2951159B1 (es)
JP (1) JP6437456B2 (es)
KR (1) KR102233081B1 (es)
CN (1) CN105452227B (es)
AU (1) AU2014209319B2 (es)
CA (1) CA2899024C (es)
DK (1) DK2951159T3 (es)
ES (1) ES2694297T3 (es)
IL (1) IL240066B (es)
MX (1) MX360048B (es)
RU (1) RU2666144C2 (es)
SG (2) SG11201505748UA (es)
TW (1) TWI685487B (es)
WO (1) WO2014116849A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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EP2357175A1 (en) 2003-06-06 2011-08-17 Fibrogen, Inc. isoquinoline derivatives AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN
CN102272117B (zh) 2008-11-14 2015-06-17 菲布罗根有限公司 作为hif羟化酶抑制剂的苯并噻喃衍生物
KR102145272B1 (ko) 2012-07-16 2020-08-18 피브로겐, 인크. 이소퀴놀린 화합물의 제조 방법
JP6491093B2 (ja) 2012-07-16 2019-03-27 フィブロジェン インコーポレイテッド プロリルヒドロキシラーゼ阻害剤の結晶形態
US8883823B2 (en) 2012-07-16 2014-11-11 Fibrogen, Inc. Crystalline forms of a prolyl hydroxylase inhibitor
MX360048B (es) 2013-01-24 2018-10-19 Fibrogen Inc Formas cristalinas de acido { [1-ciano-5-(4-clorofenoxi)-4-hidroxi -isoquinolin-3-carbonil]-amino}-acetico.
DK3003284T3 (da) 2013-06-06 2020-03-30 Fibrogen Inc Farmaceutiske formuleringer af en hif-hydroxylase-inhibitor
WO2016034108A1 (zh) 2014-09-02 2016-03-10 广东东阳光药业有限公司 喹啉酮类化合物及其应用
EP4121009A4 (en) * 2020-03-17 2024-04-17 Zydus Lifesciences Limited Formulation comprising hif prolyl hydroxylase inhibitors

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Also Published As

Publication number Publication date
ES2694297T3 (es) 2018-12-19
CA2899024C (en) 2022-01-04
CN105452227A (zh) 2016-03-30
IL240066B (en) 2019-08-29
RU2666144C2 (ru) 2018-09-06
MX2015009617A (es) 2016-04-20
DK2951159T3 (en) 2018-11-19
HK1217331A1 (en) 2017-01-06
US9643928B2 (en) 2017-05-09
SG10202009266PA (en) 2020-10-29
SG11201505748UA (en) 2015-08-28
JP2016505071A (ja) 2016-02-18
AU2014209319B2 (en) 2018-04-19
CN105452227B (zh) 2018-05-29
KR20150129679A (ko) 2015-11-20
EP2951159A1 (en) 2015-12-09
US20160002170A1 (en) 2016-01-07
RU2015134420A (ru) 2017-03-03
AU2014209319A1 (en) 2015-08-27
JP6437456B2 (ja) 2018-12-12
KR102233081B1 (ko) 2021-03-29
WO2014116849A1 (en) 2014-07-31
CA2899024A1 (en) 2014-07-31
IL240066A0 (en) 2015-09-24
TWI685487B (zh) 2020-02-21
TW201444800A (zh) 2014-12-01
EP2951159B1 (en) 2018-08-22

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