DK2951159T3 - CRYSTALLIC FORMS OF {[1-CYANO-5- (4-CHLORPHENOXY) -4-HYDROXY-ISOQUINOLIN-3-CARBONYL] -AMINO} ACETIC ACID - Google Patents
CRYSTALLIC FORMS OF {[1-CYANO-5- (4-CHLORPHENOXY) -4-HYDROXY-ISOQUINOLIN-3-CARBONYL] -AMINO} ACETIC ACID Download PDFInfo
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- DK2951159T3 DK2951159T3 DK14704030.7T DK14704030T DK2951159T3 DK 2951159 T3 DK2951159 T3 DK 2951159T3 DK 14704030 T DK14704030 T DK 14704030T DK 2951159 T3 DK2951159 T3 DK 2951159T3
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- compound
- acetic acid
- cyano
- hydroxy
- chlorophenoxy
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361756361P | 2013-01-24 | 2013-01-24 | |
| PCT/US2014/012780 WO2014116849A1 (en) | 2013-01-24 | 2014-01-23 | Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2951159T3 true DK2951159T3 (en) | 2018-11-19 |
Family
ID=50073508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14704030.7T DK2951159T3 (en) | 2013-01-24 | 2014-01-23 | CRYSTALLIC FORMS OF {[1-CYANO-5- (4-CHLORPHENOXY) -4-HYDROXY-ISOQUINOLIN-3-CARBONYL] -AMINO} ACETIC ACID |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9643928B2 (enExample) |
| EP (1) | EP2951159B1 (enExample) |
| JP (1) | JP6437456B2 (enExample) |
| KR (1) | KR102233081B1 (enExample) |
| CN (1) | CN105452227B (enExample) |
| AU (1) | AU2014209319B2 (enExample) |
| CA (1) | CA2899024C (enExample) |
| DK (1) | DK2951159T3 (enExample) |
| ES (1) | ES2694297T3 (enExample) |
| IL (1) | IL240066B (enExample) |
| MX (1) | MX360048B (enExample) |
| RU (1) | RU2666144C2 (enExample) |
| SG (2) | SG10202009266PA (enExample) |
| TW (1) | TWI685487B (enExample) |
| WO (1) | WO2014116849A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100932169B1 (ko) | 2003-06-06 | 2009-12-16 | 피브로겐, 인크. | 질소-함유 헤테로아릴 화합물 및 내인성 적혈구생성소의증가에서의 그들의 사용 |
| CN102272117B (zh) | 2008-11-14 | 2015-06-17 | 菲布罗根有限公司 | 作为hif羟化酶抑制剂的苯并噻喃衍生物 |
| US9115085B2 (en) | 2012-07-16 | 2015-08-25 | Fibrogen, Inc. | Crystalline forms of a prolyl hydroxylase inhibitor |
| US9340511B2 (en) | 2012-07-16 | 2016-05-17 | Fibrogen, Inc. | Process for making isoquinoline compounds |
| US8883823B2 (en) | 2012-07-16 | 2014-11-11 | Fibrogen, Inc. | Crystalline forms of a prolyl hydroxylase inhibitor |
| WO2014116849A1 (en) | 2013-01-24 | 2014-07-31 | Fibrogen, Inc. | Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid |
| IL296484B2 (en) | 2013-06-06 | 2025-03-01 | Fibrogen Inc | Pharmaceutical formulations of HIF hydroxylase inhibitor |
| WO2016034108A1 (zh) | 2014-09-02 | 2016-03-10 | 广东东阳光药业有限公司 | 喹啉酮类化合物及其应用 |
| EP4121009A4 (en) * | 2020-03-17 | 2024-04-17 | Zydus Lifesciences Limited | Formulation comprising hif prolyl hydroxylase inhibitors |
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| DE19746287A1 (de) | 1997-10-20 | 1999-04-22 | Hoechst Marion Roussel De Gmbh | Substituierte Isochinolin-2-Carbonsäureamide, ihre Herstellung und ihre Verwendung als Arzneimittel |
| FR2779963A1 (fr) | 1998-06-22 | 1999-12-24 | Centre Nat Rech Scient | Utilisation d'un compose possedant une affinite pour le recepteur mitochondrial des benzodiazepines en therapie du cancer |
| IT1302677B1 (it) | 1998-10-15 | 2000-09-29 | Zambon Spa | Derivati benzazinici inibitori della fosfodiesterasi 4 |
| AU4802500A (en) | 1999-04-26 | 2000-11-10 | Neurogen Corporation | 2-aminoquinolinecarboxamides: neurokinin receptor ligands |
| IT1320162B1 (it) | 2000-02-09 | 2003-11-18 | Rotta Research Lab | Derivati della tirosina ad attivita' anti leucotrienica, procedimentoper la loro preparazione e loro uso farmaceutico. |
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-
2014
- 2014-01-23 WO PCT/US2014/012780 patent/WO2014116849A1/en not_active Ceased
- 2014-01-23 SG SG10202009266PA patent/SG10202009266PA/en unknown
- 2014-01-23 TW TW103102462A patent/TWI685487B/zh not_active IP Right Cessation
- 2014-01-23 CN CN201480016402.9A patent/CN105452227B/zh not_active Expired - Fee Related
- 2014-01-23 EP EP14704030.7A patent/EP2951159B1/en active Active
- 2014-01-23 SG SG11201505748UA patent/SG11201505748UA/en unknown
- 2014-01-23 ES ES14704030.7T patent/ES2694297T3/es active Active
- 2014-01-23 US US14/763,127 patent/US9643928B2/en not_active Expired - Fee Related
- 2014-01-23 MX MX2015009617A patent/MX360048B/es active IP Right Grant
- 2014-01-23 AU AU2014209319A patent/AU2014209319B2/en not_active Ceased
- 2014-01-23 DK DK14704030.7T patent/DK2951159T3/en active
- 2014-01-23 KR KR1020157022614A patent/KR102233081B1/ko not_active Expired - Fee Related
- 2014-01-23 CA CA2899024A patent/CA2899024C/en active Active
- 2014-01-23 JP JP2015555276A patent/JP6437456B2/ja not_active Expired - Fee Related
- 2014-01-23 RU RU2015134420A patent/RU2666144C2/ru active
-
2015
- 2015-07-21 IL IL240066A patent/IL240066B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2951159A1 (en) | 2015-12-09 |
| RU2666144C2 (ru) | 2018-09-06 |
| TWI685487B (zh) | 2020-02-21 |
| AU2014209319B2 (en) | 2018-04-19 |
| IL240066A0 (en) | 2015-09-24 |
| KR20150129679A (ko) | 2015-11-20 |
| ES2694297T3 (es) | 2018-12-19 |
| JP6437456B2 (ja) | 2018-12-12 |
| SG10202009266PA (en) | 2020-10-29 |
| US20160002170A1 (en) | 2016-01-07 |
| JP2016505071A (ja) | 2016-02-18 |
| CN105452227B (zh) | 2018-05-29 |
| MX2015009617A (es) | 2016-04-20 |
| AU2014209319A1 (en) | 2015-08-27 |
| SG11201505748UA (en) | 2015-08-28 |
| WO2014116849A1 (en) | 2014-07-31 |
| CA2899024C (en) | 2022-01-04 |
| EP2951159B1 (en) | 2018-08-22 |
| RU2015134420A (ru) | 2017-03-03 |
| US9643928B2 (en) | 2017-05-09 |
| CA2899024A1 (en) | 2014-07-31 |
| IL240066B (en) | 2019-08-29 |
| HK1217331A1 (en) | 2017-01-06 |
| KR102233081B1 (ko) | 2021-03-29 |
| MX360048B (es) | 2018-10-19 |
| TW201444800A (zh) | 2014-12-01 |
| CN105452227A (zh) | 2016-03-30 |
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