ES2681948T3 - Células de acoplamiento para inmunoterapia - Google Patents
Células de acoplamiento para inmunoterapia Download PDFInfo
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- ES2681948T3 ES2681948T3 ES14714473.7T ES14714473T ES2681948T3 ES 2681948 T3 ES2681948 T3 ES 2681948T3 ES 14714473 T ES14714473 T ES 14714473T ES 2681948 T3 ES2681948 T3 ES 2681948T3
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361772803P | 2013-03-05 | 2013-03-05 | |
| US201361772803P | 2013-03-05 | ||
| US201361775524P | 2013-03-09 | 2013-03-09 | |
| US201361775524P | 2013-03-09 | ||
| US201461928383P | 2014-01-16 | 2014-01-16 | |
| US201461928383P | 2014-01-16 | ||
| US201461941729P | 2014-02-19 | 2014-02-19 | |
| US201461941729P | 2014-02-19 | ||
| PCT/US2014/020919 WO2014138306A1 (en) | 2013-03-05 | 2014-03-05 | Engager cells for immunotherapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2681948T3 true ES2681948T3 (es) | 2018-09-17 |
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| ES14714473.7T Active ES2681948T3 (es) | 2013-03-05 | 2014-03-05 | Células de acoplamiento para inmunoterapia |
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| US (2) | US20160015749A1 (OSRAM) |
| EP (2) | EP2964675B1 (OSRAM) |
| JP (2) | JP6420776B2 (OSRAM) |
| AU (1) | AU2014225788B2 (OSRAM) |
| CA (1) | CA2904230A1 (OSRAM) |
| ES (1) | ES2681948T3 (OSRAM) |
| WO (1) | WO2014138306A1 (OSRAM) |
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| JP2016512199A (ja) * | 2013-03-05 | 2016-04-25 | ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ | 腫瘍溶解性ウイルス |
| MX380176B (es) | 2014-04-07 | 2025-03-12 | Chugai Pharmaceutical Co Ltd | Molecula ligada a antigeno inmunoactivada. |
| CN106459954A (zh) | 2014-05-13 | 2017-02-22 | 中外制药株式会社 | 用于具有免疫抑制功能的细胞的t细胞重定向的抗原结合分子 |
| JP7372728B2 (ja) * | 2014-10-31 | 2023-11-01 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 改変ｔ細胞に関する方法および組成物 |
| AU2015346205B2 (en) * | 2014-11-12 | 2021-07-29 | Memorial Sloan Kettering Cancer Center | Anti-chondroitin sulfate proteoglycan 4 antibodies and uses thereof |
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| EP3359168A4 (en) * | 2015-10-06 | 2019-08-07 | Regents of the University of Minnesota | THERAPEUTIC COMPOUNDS AND METHOD |
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| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
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| GB9304200D0 (en) | 1993-03-02 | 1993-04-21 | Sandoz Ltd | Improvements in or relating to organic compounds |
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| JP2009521474A (ja) * | 2005-12-21 | 2009-06-04 | メディミューン，エルエルシー | ＥｐｈＡ２ＢｉＴＥ分子およびその使用 |
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| WO2009091826A2 (en) * | 2008-01-14 | 2009-07-23 | The Board Of Regents Of The University Of Texas System | Compositions and methods related to a human cd19-specific chimeric antigen receptor (h-car) |
| US20120034228A1 (en) * | 2008-10-01 | 2012-02-09 | Micromet Ag | CROSS-SPECIES-SPECIFIC PSCAxCD3, CD19xCD3, C-METxCD3, ENDOSIALINxCD3, EPCAMxCD3, IGF-1RxCD3 OR FAPALPHAxCD3 BISPECIFIC SINGLE CHAIN ANTIBODY |
| US20130273055A1 (en) * | 2010-11-16 | 2013-10-17 | Eric Borges | Agents and methods for treating diseases that correlate with bcma expression |
| PH12013501201A1 (en) * | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| US20130071414A1 (en) * | 2011-04-27 | 2013-03-21 | Gianpietro Dotti | Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies |
| JP2015524255A (ja) | 2012-07-13 | 2015-08-24 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 二重特異性抗体を共導入することによってｃａｒｔ細胞の活性を強化する方法 |
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2014
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- 2014-03-05 JP JP2015561624A patent/JP6420776B2/ja not_active Expired - Fee Related
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| EP2964675B1 (en) | 2018-06-20 |
| JP6420776B2 (ja) | 2018-11-07 |
| US20190117692A1 (en) | 2019-04-25 |
| HK1219967A1 (en) | 2017-04-21 |
| AU2014225788B2 (en) | 2018-03-29 |
| US20160015749A1 (en) | 2016-01-21 |
| AU2014225788A1 (en) | 2015-10-08 |
| WO2014138306A1 (en) | 2014-09-12 |
| JP2019024499A (ja) | 2019-02-21 |
| EP3447072A2 (en) | 2019-02-27 |
| JP2016514956A (ja) | 2016-05-26 |
| EP3447072A3 (en) | 2019-05-22 |
| JP6867347B2 (ja) | 2021-04-28 |
| EP2964675A1 (en) | 2016-01-13 |
| CA2904230A1 (en) | 2014-09-12 |
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