ES2659718T3 - Anticuerpos anti-GT468 monoclonales para el tratamiento del cáncer - Google Patents
Anticuerpos anti-GT468 monoclonales para el tratamiento del cáncer Download PDFInfo
- Publication number
- ES2659718T3 ES2659718T3 ES09778564.6T ES09778564T ES2659718T3 ES 2659718 T3 ES2659718 T3 ES 2659718T3 ES 09778564 T ES09778564 T ES 09778564T ES 2659718 T3 ES2659718 T3 ES 2659718T3
- Authority
- ES
- Spain
- Prior art keywords
- seq
- dsm
- antibody
- dna
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9745308P | 2008-09-16 | 2008-09-16 | |
| EP08016277 | 2008-09-16 | ||
| EP08016277A EP2166021A1 (en) | 2008-09-16 | 2008-09-16 | Monoclonal antibodies for treatment of cancer |
| US97453P | 2008-09-16 | ||
| PCT/EP2009/006704 WO2010031551A2 (en) | 2008-09-16 | 2009-09-16 | Monoclonal antibodies for treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2659718T3 true ES2659718T3 (es) | 2018-03-19 |
Family
ID=40589589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09778564.6T Active ES2659718T3 (es) | 2008-09-16 | 2009-09-16 | Anticuerpos anti-GT468 monoclonales para el tratamiento del cáncer |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US8946388B2 (https=) |
| EP (3) | EP2166021A1 (https=) |
| JP (1) | JP2012502938A (https=) |
| KR (1) | KR101818741B1 (https=) |
| CN (3) | CN102164963B (https=) |
| AU (1) | AU2009294896B2 (https=) |
| BR (1) | BRPI0918178B8 (https=) |
| CA (1) | CA2732594C (https=) |
| CY (1) | CY1119956T1 (https=) |
| DK (1) | DK2342234T3 (https=) |
| ES (1) | ES2659718T3 (https=) |
| HK (1) | HK1253579A1 (https=) |
| HR (1) | HRP20180262T1 (https=) |
| HU (1) | HUE036477T2 (https=) |
| IL (2) | IL211010A (https=) |
| LT (1) | LT2342234T (https=) |
| MX (2) | MX357010B (https=) |
| NO (1) | NO2342234T3 (https=) |
| NZ (2) | NZ591004A (https=) |
| PL (1) | PL2342234T3 (https=) |
| PT (1) | PT2342234T (https=) |
| RS (1) | RS56937B1 (https=) |
| SI (1) | SI2342234T1 (https=) |
| SM (1) | SMT201800079T1 (https=) |
| TR (1) | TR201802090T4 (https=) |
| WO (1) | WO2010031551A2 (https=) |
| ZA (1) | ZA201100835B (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1762575A1 (en) | 2005-09-12 | 2007-03-14 | Ganymed Pharmaceuticals AG | Identification of tumor-associated antigens for diagnosis and therapy |
| EP1970384A1 (en) | 2007-03-14 | 2008-09-17 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| EP4464384A3 (en) | 2007-08-17 | 2025-01-08 | Purdue Research Foundation | Psma binding ligand-linker conjugates and methods for using |
| EP2166021A1 (en) | 2008-09-16 | 2010-03-24 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
| EP2371864A1 (en) | 2010-03-23 | 2011-10-05 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| RU2597831C2 (ru) * | 2011-01-19 | 2016-09-20 | Кантаргия Аб | Анти-il1rap антитела и их применение при лечении людей |
| US20130236890A1 (en) * | 2012-03-08 | 2013-09-12 | HI-STEM Heidelberg Institute for Stem Cell Technology and Experimental Medicine gGmbH | Novel method for analyzing circulating tumor cells of a patient for the presence of metastasis-initiating cells |
| KR101471253B1 (ko) * | 2012-10-29 | 2014-12-10 | 인제대학교 산학협력단 | 암 표적 항체 및 이를 포함하는 암 예방 또는 치료용 조성물 |
| BR112015011118B1 (pt) | 2012-11-15 | 2022-12-13 | Endocyte, Inc | Conjugado; composição farmacêutica; e uso de um conjugado |
| LT4095130T (lt) | 2013-10-18 | 2024-04-25 | Novartis Ag | Žymėti prostatos specifinio membranos antigeno (psma) inhibitoriai, jų naudojimas kaip vizualizavimo medžiagų ir farmacinių medžiagų prostatos vėžiui gydyti |
| BR112016010927A2 (pt) | 2013-11-14 | 2017-08-08 | Endocyte Inc | Conjugado de fórmula |
| JP2017521998A (ja) * | 2014-05-12 | 2017-08-10 | ヌマブ アクチェンゲゼルシャフト | 新規多重特異性分子及びかかる多重特異性分子に基づく新規治療方法 |
| US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
| EP3770171A1 (en) * | 2015-04-03 | 2021-01-27 | XOMA Technology Ltd. | Treatment of cancer using inhibitors of tgf-beta and pd-1 |
| WO2017011559A1 (en) * | 2015-07-14 | 2017-01-19 | Medlmmune, Llc | Compositions and methods for treating cancer |
| KR20180039726A (ko) | 2015-09-04 | 2018-04-18 | 더 캘리포니아 인스티튜트 포 바이오메디칼 리써치 | 인슐린 면역글로불린 융합 단백질 |
| MA43365A (fr) * | 2015-12-01 | 2018-10-10 | Genmab Bv | Anticorps anti-dr5 et procédés d'utilisation de ceux-ci |
| BR112019008010A2 (pt) | 2016-10-20 | 2019-07-09 | I-Mab | anticorpo monoclonal isolado ou fragmento imunologicamente ativo do mesmo, anticorpo monoclonal biespecífico isolado, composição farmacêutica, método para tratamento de uma doença em um sujeito humano em necessidade do mesmo, proteína de fusão, epítopo imunodominante codificado pelo gene cd47, e, molécula biológica |
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| CN106632661A (zh) * | 2017-01-10 | 2017-05-10 | 天津东亚生物技术有限公司 | 利用hla‑g分子及其抗原片段制备预防肿瘤和病毒病的广谱疫苗及其应用 |
| JP2020513819A (ja) * | 2017-03-15 | 2020-05-21 | スージョウ ギャラクシー バイオファーマ カンパニー リミテッド | Ctla4抗体、医薬組成物およびその使用 |
| CN107556369A (zh) * | 2017-08-23 | 2018-01-09 | 天津国际生物医药联合研究院 | 一种抗原肽和用于检测肿瘤细胞的抗体制备方法及其应用 |
| US12208102B2 (en) | 2018-04-17 | 2025-01-28 | Endocyte, Inc. | Methods of treating cancer |
| CN109402064B (zh) * | 2018-11-05 | 2021-05-14 | 湖南省肿瘤医院 | 杂交瘤细胞株及其产生的单克隆抗体和应用 |
| CN114096264B (zh) | 2019-05-20 | 2025-03-14 | 因多塞特股份有限公司 | 制备psma缀合物的方法 |
| KR102266418B1 (ko) * | 2019-07-30 | 2021-06-16 | 한국생명공학연구원 | 영여자 추출물을 유효성분으로 함유하는 전립선 질환의 예방 및 치료용 조성물 |
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| US4475196A (en) | 1981-03-06 | 1984-10-02 | Zor Clair G | Instrument for locating faults in aircraft passenger reading light and attendant call control system |
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4474893A (en) | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| US4486194A (en) | 1983-06-08 | 1984-12-04 | James Ferrara | Therapeutic device for administering medicaments through the skin |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| US5374548A (en) | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
| MX9203291A (es) | 1985-06-26 | 1992-08-01 | Liposome Co Inc | Metodo para acoplamiento de liposomas. |
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| US4954617A (en) | 1986-07-07 | 1990-09-04 | Trustees Of Dartmouth College | Monoclonal antibodies to FC receptors for immunoglobulin G on human mononuclear phagocytes |
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| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4881175A (en) | 1986-09-02 | 1989-11-14 | Genex Corporation | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
| WO1988007089A1 (en) | 1987-03-18 | 1988-09-22 | Medical Research Council | Altered antibodies |
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| ATE243754T1 (de) | 1987-05-21 | 2003-07-15 | Micromet Ag | Multifunktionelle proteine mit vorbestimmter zielsetzung |
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| WO2003075014A2 (en) | 2002-03-06 | 2003-09-12 | Oxford Glycosciences (Uk) Ltd | Protein-protein interactions in human tumours involving bcmp-7 and bcmp-11 |
| CN101928344B (zh) | 2002-10-17 | 2014-08-13 | 根马布股份公司 | 抗cd20的人单克隆抗体 |
| WO2004065629A1 (en) | 2003-01-17 | 2004-08-05 | The Chinese University Of Hong Kong | Circulating mrna as diagnostic markers for pregnancy-related disorders |
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| CN1663603A (zh) | 2004-03-02 | 2005-09-07 | 北京大学 | 一种肿瘤-胎盘抗原蛋白及其dna在肿瘤治疗中的应用 |
| EP1762575A1 (en) | 2005-09-12 | 2007-03-14 | Ganymed Pharmaceuticals AG | Identification of tumor-associated antigens for diagnosis and therapy |
| EP1970384A1 (en) * | 2007-03-14 | 2008-09-17 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| EP2166021A1 (en) | 2008-09-16 | 2010-03-24 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| LT2398902T (lt) * | 2009-02-20 | 2023-12-27 | Astellas Pharma Inc. | Vėžio diagnostikos ir gydymo būdai bei kompozicijos |
| EP2221063A1 (en) * | 2009-02-20 | 2010-08-25 | Ganymed Pharmaceuticals AG | Methods and compositions for diagnosis and treatment of cancer |
-
2008
- 2008-09-16 EP EP08016277A patent/EP2166021A1/en not_active Withdrawn
-
2009
- 2009-09-16 AU AU2009294896A patent/AU2009294896B2/en not_active Ceased
- 2009-09-16 EP EP09778564.6A patent/EP2342234B1/en active Active
- 2009-09-16 PL PL09778564T patent/PL2342234T3/pl unknown
- 2009-09-16 WO PCT/EP2009/006704 patent/WO2010031551A2/en not_active Ceased
- 2009-09-16 US US13/119,027 patent/US8946388B2/en not_active Expired - Fee Related
- 2009-09-16 NO NO09778564A patent/NO2342234T3/no unknown
- 2009-09-16 KR KR1020117007149A patent/KR101818741B1/ko not_active Expired - Fee Related
- 2009-09-16 NZ NZ591004A patent/NZ591004A/en not_active IP Right Cessation
- 2009-09-16 CN CN200980136101.9A patent/CN102164963B/zh not_active Expired - Fee Related
- 2009-09-16 DK DK09778564.6T patent/DK2342234T3/en active
- 2009-09-16 SI SI200931801T patent/SI2342234T1/en unknown
- 2009-09-16 EP EP17201134.8A patent/EP3312198A1/en not_active Withdrawn
- 2009-09-16 HR HRP20180262TT patent/HRP20180262T1/hr unknown
- 2009-09-16 CA CA2732594A patent/CA2732594C/en not_active Expired - Fee Related
- 2009-09-16 SM SM20180079T patent/SMT201800079T1/it unknown
- 2009-09-16 CN CN201410649373.1A patent/CN104628858B/zh not_active Expired - Fee Related
- 2009-09-16 CN CN201510373379.5A patent/CN105753988A/zh active Pending
- 2009-09-16 MX MX2015005367A patent/MX357010B/es unknown
- 2009-09-16 MX MX2011002856A patent/MX2011002856A/es active IP Right Grant
- 2009-09-16 BR BRPI0918178A patent/BRPI0918178B8/pt not_active IP Right Cessation
- 2009-09-16 NZ NZ596490A patent/NZ596490A/xx not_active IP Right Cessation
- 2009-09-16 HU HUE09778564A patent/HUE036477T2/hu unknown
- 2009-09-16 JP JP2011527243A patent/JP2012502938A/ja active Pending
- 2009-09-16 PT PT97785646T patent/PT2342234T/pt unknown
- 2009-09-16 RS RS20180160A patent/RS56937B1/sr unknown
- 2009-09-16 TR TR2018/02090T patent/TR201802090T4/tr unknown
- 2009-09-16 ES ES09778564.6T patent/ES2659718T3/es active Active
- 2009-09-16 LT LTEP09778564.6T patent/LT2342234T/lt unknown
-
2011
- 2011-02-01 ZA ZA2011/00835A patent/ZA201100835B/en unknown
- 2011-02-02 IL IL211010A patent/IL211010A/en not_active IP Right Cessation
-
2015
- 2015-10-22 IL IL242204A patent/IL242204B/en active IP Right Grant
-
2018
- 2018-02-15 CY CY20181100189T patent/CY1119956T1/el unknown
- 2018-10-08 HK HK18112784.5A patent/HK1253579A1/en unknown
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