ES2580379T3 - Biomarcadores de microARN indicativos de la enfermedad de Alzheimer - Google Patents

Biomarcadores de microARN indicativos de la enfermedad de Alzheimer Download PDF

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Publication number
ES2580379T3
ES2580379T3 ES12750628.5T ES12750628T ES2580379T3 ES 2580379 T3 ES2580379 T3 ES 2580379T3 ES 12750628 T ES12750628 T ES 12750628T ES 2580379 T3 ES2580379 T3 ES 2580379T3
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Spain
Prior art keywords
mirna
mir
sample
disease
alzheimer
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ES12750628.5T
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English (en)
Spanish (es)
Inventor
Zoltan DEZSO
Pavan Kumar
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Eisai R&D Management Co Ltd
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Eisai R&D Management Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ES12750628.5T 2011-06-27 2012-06-26 Biomarcadores de microARN indicativos de la enfermedad de Alzheimer Active ES2580379T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161501720P 2011-06-27 2011-06-27
US201161501720P 2011-06-27
PCT/US2012/044202 WO2013003350A2 (en) 2011-06-27 2012-06-26 Microrna biomarkers indicative of alzheimer's disease

Publications (1)

Publication Number Publication Date
ES2580379T3 true ES2580379T3 (es) 2016-08-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
ES12750628.5T Active ES2580379T3 (es) 2011-06-27 2012-06-26 Biomarcadores de microARN indicativos de la enfermedad de Alzheimer

Country Status (13)

Country Link
US (1) US9771617B2 (enExample)
EP (1) EP2723894B1 (enExample)
JP (2) JP6154809B2 (enExample)
KR (1) KR102082016B1 (enExample)
CN (1) CN103781919B9 (enExample)
AU (1) AU2012275556B2 (enExample)
BR (1) BR112013033488B8 (enExample)
CA (1) CA2840196C (enExample)
ES (1) ES2580379T3 (enExample)
IL (1) IL230034B (enExample)
MX (1) MX341840B (enExample)
RU (1) RU2639509C2 (enExample)
WO (1) WO2013003350A2 (enExample)

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KR101998457B1 (ko) * 2016-05-10 2019-07-10 조선대학교산학협력단 알츠하이머 질병의 진단을 위한 바이오마커
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WO2019094780A2 (en) * 2017-11-12 2019-05-16 The Regents Of The University Of California Non-coding rna for detection of cancer
WO2019117306A1 (ja) 2017-12-14 2019-06-20 国立大学法人広島大学 アルツハイマー病の検出を補助する方法
CN108277271A (zh) * 2018-02-05 2018-07-13 范瑶飞 一种辅助检测阿兹海默疾病的miRNA
WO2019159884A1 (ja) * 2018-02-13 2019-08-22 東レ株式会社 認知症の検出のためのキット又はデバイス及び方法
US12054779B2 (en) 2018-06-15 2024-08-06 Universitat Autònoma De Barcelona Circulating miRNAs as biomarkers for diagnosis of mild cognitive impairment and Alzheimer's disease
KR20210038585A (ko) * 2018-07-25 2021-04-07 에스알엔에이리틱스, 인크. 알츠하이머병에 대한 작은 rna 예측인자
JP6884810B2 (ja) * 2019-05-08 2021-06-09 キユーピー株式会社 情報提供装置、情報提供方法及びmiRNA重要度テーブル生成方法
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Also Published As

Publication number Publication date
BR112013033488A2 (pt) 2017-03-01
WO2013003350A2 (en) 2013-01-03
IL230034B (en) 2021-02-28
AU2012275556B2 (en) 2016-02-04
BR112013033488B8 (pt) 2022-11-22
MX341840B (es) 2016-09-05
CA2840196C (en) 2022-09-20
RU2014102357A (ru) 2015-08-10
MX2013015392A (es) 2014-07-14
KR102082016B1 (ko) 2020-02-26
CN103781919B (zh) 2017-07-04
RU2639509C2 (ru) 2017-12-21
EP2723894A2 (en) 2014-04-30
JP2016214256A (ja) 2016-12-22
WO2013003350A3 (en) 2013-04-11
CN103781919A (zh) 2014-05-07
KR20140044375A (ko) 2014-04-14
US9771617B2 (en) 2017-09-26
AU2012275556A1 (en) 2013-05-02
EP2723894B1 (en) 2016-05-11
CN103781919B9 (zh) 2017-09-15
BR112013033488B1 (pt) 2022-03-03
CA2840196A1 (en) 2013-01-03
JP6154809B2 (ja) 2017-06-28
US20140378439A1 (en) 2014-12-25
JP2014520529A (ja) 2014-08-25

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