ES2562205T3 - Hibrídos de curcumina resveratrol - Google Patents
Hibrídos de curcumina resveratrol Download PDFInfo
- Publication number
- ES2562205T3 ES2562205T3 ES14153876.9T ES14153876T ES2562205T3 ES 2562205 T3 ES2562205 T3 ES 2562205T3 ES 14153876 T ES14153876 T ES 14153876T ES 2562205 T3 ES2562205 T3 ES 2562205T3
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- Prior art keywords
- curcumin
- brain
- resveratrol
- phenolic
- reports
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Otolaryngology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
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|---|---|---|---|
| US11/736,278 US20080076821A1 (en) | 2006-09-22 | 2007-04-17 | Intranasally administering curcumin prodrugs to the brain to treat alzheimer's disease |
| US736278 | 2007-04-17 | ||
| US29904 | 2008-02-12 | ||
| US12/029,904 US20090087385A1 (en) | 2006-09-22 | 2008-02-12 | Intranasally administering curcumin in a bolus of helium gas to treat alzheimers disease |
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| ES2562205T3 true ES2562205T3 (es) | 2016-03-03 |
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| EP (2) | EP2749552B1 (OSRAM) |
| JP (1) | JP2010524959A (OSRAM) |
| ES (1) | ES2562205T3 (OSRAM) |
| WO (1) | WO2008131059A2 (OSRAM) |
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| WO2008131059A2 (en) | 2007-04-17 | 2008-10-30 | Codman & Shurtleff, Inc. | Intranasally administering curcumin in a bolus of helium gas to treat alzheimer's disease |
| US8383865B2 (en) | 2007-04-17 | 2013-02-26 | Codman & Shurtleff, Inc. | Curcumin derivatives |
| US7745670B2 (en) | 2008-06-27 | 2010-06-29 | Codman & Shurtleff, Inc. | Curcumin-Resveratrol hybrid molecule |
| US7985776B2 (en) | 2008-06-27 | 2011-07-26 | Codman & Shurtleff, Inc. | Iontophoretic delivery of curcumin and curcumin analogs for the treatment of Alzheimer's Disease |
| KR101095026B1 (ko) | 2009-01-23 | 2011-12-20 | 한국과학기술연구원 | 비스(스티릴)피리미딘 및 비스(스티릴)벤젠 유도체, 이의 약학적으로 허용 가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 베타아밀로이드 집적 관련 질환의 예방 또는 치료용 약학적 조성물 |
| US7723515B1 (en) | 2009-01-26 | 2010-05-25 | Codman & Shurtleff, Inc. | Methylene blue—curcumin analog for the treatment of alzheimer's disease |
| WO2011160093A2 (en) * | 2010-06-17 | 2011-12-22 | California Institute Of Technology | Methods and systems for modulating hormones and related methods, agents and compositions |
| WO2012137225A1 (en) * | 2011-04-08 | 2012-10-11 | Sphaera Pharma Pvt. Ltd | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds |
| US8846013B2 (en) | 2012-06-29 | 2014-09-30 | Johnson & Johnson Consumer Companies, Inc. | Topical application of 1-hydroxyl-3,5-BIS(4′hydroxy styryl)benzene |
| US8758731B2 (en) | 2012-06-29 | 2014-06-24 | Johnson & Johnson Consumer Companies, Inc. | Skin lightening by topical application of 1-hydroxyl 3,5-bis(4′hydroxyl styryl)benzene |
| CA2913296A1 (en) * | 2013-05-23 | 2014-11-27 | Neurosn, Inc. | Diagnosing and treating alzheimer's disease using annexins with labeled with a radionuclide |
| EP3074028B1 (en) * | 2013-11-27 | 2022-04-06 | Research Foundation Of The City University Of New York | Activity enhancing curcumin compositions and methods of use |
| WO2017011318A1 (en) | 2015-07-10 | 2017-01-19 | University Of Miami | Methods for treating mucopolysaccharidosis |
| DE102015008823A1 (de) * | 2015-07-15 | 2017-01-19 | Hans Muerth | Verwendung des Verfahrens und der Vorichtungen zum Verdampfen von Curcumin-Pulver mit einem Hochleistungs-Verdampfer zwecks Erzeugen eines inhalierbaren Curcumin-Aerosols |
| EP3455201A1 (en) | 2016-05-10 | 2019-03-20 | Basf Se | Process for the manufacture of hydroxy-substituted aromatic compounds |
| US10707531B1 (en) | 2016-09-27 | 2020-07-07 | New Dominion Enterprises Inc. | All-inorganic solvents for electrolytes |
| WO2020144753A1 (ja) * | 2019-01-09 | 2020-07-16 | 公立大学法人大阪 | 神経変性疾患の予防又は治療薬 |
| AU2020407239B2 (en) * | 2019-12-18 | 2025-11-27 | Burke Neurological Institute | Methods of treating brain disorders |
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| US4208511A (en) | 1977-01-19 | 1980-06-17 | Ethicon, Inc. | Isomorphic copolyoxalates and sutures thereof |
| US4141087A (en) | 1977-01-19 | 1979-02-27 | Ethicon, Inc. | Isomorphic copolyoxalates and sutures thereof |
| US4105034A (en) | 1977-06-10 | 1978-08-08 | Ethicon, Inc. | Poly(alkylene oxalate) absorbable coating for sutures |
| US4140678A (en) | 1977-06-13 | 1979-02-20 | Ethicon, Inc. | Synthetic absorbable surgical devices of poly(alkylene oxalates) |
| US4205399A (en) | 1977-06-13 | 1980-06-03 | Ethicon, Inc. | Synthetic absorbable surgical devices of poly(alkylene oxalates) |
| US4130639A (en) | 1977-09-28 | 1978-12-19 | Ethicon, Inc. | Absorbable pharmaceutical compositions based on isomorphic copolyoxalates |
| DK147640C (da) | 1982-06-11 | 1985-05-06 | Dumex Ltd As | Fremgangsmaade til fremstilling af nitroimidazol-derivater |
| US4529556A (en) * | 1983-08-19 | 1985-07-16 | The Dow Chemical Company | Bis((aryl)vinyl)benzenes |
| DK406686D0 (da) | 1986-08-26 | 1986-08-26 | Hans Bundgaard | Carboxylsyrederivater |
| DK24089D0 (da) | 1989-01-20 | 1989-01-20 | Hans Bundgaard | Novel prodrug derivatives of biologically active agents containing hydroxyl groups or nh-acidic groups |
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| DE4137540A1 (de) * | 1991-11-14 | 1993-05-19 | Steigerwald Arzneimittelwerk | Verwendung von praeparaten der curcuma-pflanzen |
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-
2008
- 2008-04-17 WO PCT/US2008/060569 patent/WO2008131059A2/en not_active Ceased
- 2008-04-17 ES ES14153876.9T patent/ES2562205T3/es active Active
- 2008-04-17 EP EP14153876.9A patent/EP2749552B1/en not_active Not-in-force
- 2008-04-17 JP JP2010504239A patent/JP2010524959A/ja active Pending
- 2008-04-17 EP EP08746053.1A patent/EP2136797A4/en not_active Withdrawn
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2010
- 2010-05-13 US US12/779,486 patent/US8350093B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008131059A3 (en) | 2010-01-21 |
| WO2008131059A2 (en) | 2008-10-30 |
| JP2010524959A (ja) | 2010-07-22 |
| US20100292512A1 (en) | 2010-11-18 |
| EP2749552A1 (en) | 2014-07-02 |
| EP2136797A4 (en) | 2013-08-21 |
| EP2136797A2 (en) | 2009-12-30 |
| EP2749552B1 (en) | 2015-11-18 |
| US8350093B2 (en) | 2013-01-08 |
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