DK147640C - Fremgangsmaade til fremstilling af nitroimidazol-derivater - Google Patents

Fremgangsmaade til fremstilling af nitroimidazol-derivater

Info

Publication number
DK147640C
DK147640C DK264382A DK264382A DK147640C DK 147640 C DK147640 C DK 147640C DK 264382 A DK264382 A DK 264382A DK 264382 A DK264382 A DK 264382A DK 147640 C DK147640 C DK 147640C
Authority
DK
Denmark
Prior art keywords
preparing
nitroimidazole derivatives
acid addition
addition salt
ester
Prior art date
Application number
DK264382A
Other languages
English (en)
Other versions
DK147640B (da
DK264382A (da
Inventor
Pia Thorbek
Hans Bundgaard
Claus Larsen
Original Assignee
Dumex Ltd As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dumex Ltd As filed Critical Dumex Ltd As
Priority to DK264382A priority Critical patent/DK147640C/da
Priority to AU15365/83A priority patent/AU564952B2/en
Priority to ZA834090A priority patent/ZA834090B/xx
Priority to US06/502,210 priority patent/US4482722A/en
Priority to NO832089A priority patent/NO157619C/no
Priority to PT76844A priority patent/PT76844B/pt
Priority to JP58104071A priority patent/JPS5925377A/ja
Priority to EP83105717A priority patent/EP0096870B1/en
Priority to AT83105717T priority patent/ATE22558T1/de
Priority to DE8383105717T priority patent/DE3366566D1/de
Priority to FI832098A priority patent/FI832098L/fi
Priority to CA000430125A priority patent/CA1188305A/en
Priority to NZ204530A priority patent/NZ204530A/en
Priority to ES523174A priority patent/ES523174A0/es
Publication of DK264382A publication Critical patent/DK264382A/da
Publication of DK147640B publication Critical patent/DK147640B/da
Application granted granted Critical
Publication of DK147640C publication Critical patent/DK147640C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK264382A 1982-06-11 1982-06-11 Fremgangsmaade til fremstilling af nitroimidazol-derivater DK147640C (da)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DK264382A DK147640C (da) 1982-06-11 1982-06-11 Fremgangsmaade til fremstilling af nitroimidazol-derivater
AU15365/83A AU564952B2 (en) 1982-06-11 1983-06-03 N,n-dimethylglycine ester of metronidazole
ZA834090A ZA834090B (en) 1982-06-11 1983-06-06 Ester of metronidazole with n,n-dimethylglycine and acid addition salt thereof
US06/502,210 US4482722A (en) 1982-06-11 1983-06-08 Ester of metronidazole with N,N-dimethylglycine and acid addition salt thereof
PT76844A PT76844B (en) 1982-06-11 1983-06-09 Ester of letronidazole with n,n-dimethylglycine and acid addition salt thereof
NO832089A NO157619C (no) 1982-06-11 1983-06-09 Analogifremgangsmaate for fremstilling av terapeutisk virksom n,n-dim-ethylglycinester av 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazol og syreaddisjonssalter derav.
JP58104071A JPS5925377A (ja) 1982-06-11 1983-06-10 メトロニダゾ−ルとｎ，ｎ−ジメチルグリシンとのエステルおよびその酸付加湿
EP83105717A EP0096870B1 (en) 1982-06-11 1983-06-10 Ester of metronidazole with n,n-dimethylglycine and acid addition salt thereof
AT83105717T ATE22558T1 (de) 1982-06-11 1983-06-10 Ester von metronidazol mit n,n-dimethylglycin und deren saeureadditionssalze.
DE8383105717T DE3366566D1 (en) 1982-06-11 1983-06-10 Ester of metronidazole with n,n-dimethylglycine and acid addition salt thereof
FI832098A FI832098L (fi) 1982-06-11 1983-06-10 N,n-dimetylglycinester av metronidazol och dennas syraadditionssalt
CA000430125A CA1188305A (en) 1982-06-11 1983-06-10 Ester of metronidazole with n,n-dimethylglycine and acid addition salt thereof
NZ204530A NZ204530A (en) 1982-06-11 1983-06-10 A metronidazole ester
ES523174A ES523174A0 (es) 1982-06-11 1983-06-10 Procedimiento para preparar un ester de metronidazol.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK264382 1982-06-11
DK264382A DK147640C (da) 1982-06-11 1982-06-11 Fremgangsmaade til fremstilling af nitroimidazol-derivater

Publications (3)

Publication Number Publication Date
DK264382A DK264382A (da) 1983-12-12
DK147640B DK147640B (da) 1984-10-29
DK147640C true DK147640C (da) 1985-05-06

Family

ID=8114115

Family Applications (1)

Application Number Title Priority Date Filing Date
DK264382A DK147640C (da) 1982-06-11 1982-06-11 Fremgangsmaade til fremstilling af nitroimidazol-derivater

Country Status (14)

Country Link
US (1) US4482722A (da)
EP (1) EP0096870B1 (da)
JP (1) JPS5925377A (da)
AT (1) ATE22558T1 (da)
AU (1) AU564952B2 (da)
CA (1) CA1188305A (da)
DE (1) DE3366566D1 (da)
DK (1) DK147640C (da)
ES (1) ES523174A0 (da)
FI (1) FI832098L (da)
NO (1) NO157619C (da)
NZ (1) NZ204530A (da)
PT (1) PT76844B (da)
ZA (1) ZA834090B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0127274A3 (en) * 1983-03-25 1987-05-20 The Upjohn Company Esters of metronidazole and compositions containing them
US4943579A (en) * 1987-10-06 1990-07-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble prodrugs of camptothecin
US6423707B1 (en) 2000-08-28 2002-07-23 California Pacific Medical Center Nitroimidazole ester analogues and therapeutic applications
EP1685114B1 (en) * 2003-10-28 2008-10-15 Ems S.A. Antibacterial and/or antiprotozoal nitroimidazole derivative compounds with urease inhibitor activity, process for preparing these compounds and use in pharmaceutical compositions and medicines.
US7244765B2 (en) * 2004-06-25 2007-07-17 Cytokine Pharmasciences, Inc Guanylhydrazone salts, compositions, processes of making and methods of using
US8383865B2 (en) * 2007-04-17 2013-02-26 Codman & Shurtleff, Inc. Curcumin derivatives
ES2562205T3 (es) 2007-04-17 2016-03-03 Codman & Shurtleff, Inc. Hibrídos de curcumina resveratrol
US7745670B2 (en) * 2008-06-27 2010-06-29 Codman & Shurtleff, Inc. Curcumin-Resveratrol hybrid molecule
US7985776B2 (en) * 2008-06-27 2011-07-26 Codman & Shurtleff, Inc. Iontophoretic delivery of curcumin and curcumin analogs for the treatment of Alzheimer's Disease
US20100286585A1 (en) * 2009-01-26 2010-11-11 Codman & Shurtleff, Inc. Shunt Delivery of Curcumin
US7723515B1 (en) 2009-01-26 2010-05-25 Codman & Shurtleff, Inc. Methylene blue—curcumin analog for the treatment of alzheimer's disease
US20240285657A1 (en) * 2023-02-28 2024-08-29 Verte Therapeutics, LLC Veterinary formulation of metronidazole, and related methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2944061A (en) * 1957-09-20 1960-07-05 Acyl derivatives and process
US3803165A (en) * 1972-08-14 1974-04-09 Hoffmann La Roche N-(2-(2-nitro-1-imidazolyl)ethyl)-2',2',2'-trichloroethyl carbamate

Also Published As

Publication number Publication date
CA1188305A (en) 1985-06-04
ES8601149A1 (es) 1985-11-01
EP0096870A1 (en) 1983-12-28
ATE22558T1 (de) 1986-10-15
ES523174A0 (es) 1985-11-01
FI832098L (fi) 1983-12-12
JPS5925377A (ja) 1984-02-09
US4482722A (en) 1984-11-13
NO832089L (no) 1983-12-12
PT76844A (en) 1983-07-01
NZ204530A (en) 1986-05-09
NO157619B (no) 1988-01-11
ZA834090B (en) 1984-02-29
DK147640B (da) 1984-10-29
EP0096870B1 (en) 1986-10-01
DE3366566D1 (en) 1986-11-06
FI832098A0 (fi) 1983-06-10
PT76844B (en) 1986-01-15
AU1536583A (en) 1983-12-15
NO157619C (no) 1988-04-20
DK264382A (da) 1983-12-12
AU564952B2 (en) 1987-09-03

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