DK264382A - Fremgangsmaade til fremstilling af nitroimidazol-derivater - Google Patents
Fremgangsmaade til fremstilling af nitroimidazol-derivater Download PDFInfo
- Publication number
- DK264382A DK264382A DK264382A DK264382A DK264382A DK 264382 A DK264382 A DK 264382A DK 264382 A DK264382 A DK 264382A DK 264382 A DK264382 A DK 264382A DK 264382 A DK264382 A DK 264382A
- Authority
- DK
- Denmark
- Prior art keywords
- preparing
- nitroimidazole derivatives
- acid addition
- addition salt
- ester
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK264382A DK147640C (da) | 1982-06-11 | 1982-06-11 | Fremgangsmaade til fremstilling af nitroimidazol-derivater |
| AU15365/83A AU564952B2 (en) | 1982-06-11 | 1983-06-03 | N,n-dimethylglycine ester of metronidazole |
| ZA834090A ZA834090B (en) | 1982-06-11 | 1983-06-06 | Ester of metronidazole with n,n-dimethylglycine and acid addition salt thereof |
| US06/502,210 US4482722A (en) | 1982-06-11 | 1983-06-08 | Ester of metronidazole with N,N-dimethylglycine and acid addition salt thereof |
| NO832089A NO157619C (no) | 1982-06-11 | 1983-06-09 | Analogifremgangsmaate for fremstilling av terapeutisk virksom n,n-dim-ethylglycinester av 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazol og syreaddisjonssalter derav. |
| PT76844A PT76844B (en) | 1982-06-11 | 1983-06-09 | Ester of letronidazole with n,n-dimethylglycine and acid addition salt thereof |
| JP58104071A JPS5925377A (ja) | 1982-06-11 | 1983-06-10 | メトロニダゾ−ルとn,n−ジメチルグリシンとのエステルおよびその酸付加湿 |
| FI832098A FI832098L (fi) | 1982-06-11 | 1983-06-10 | N,n-dimetylglycinester av metronidazol och dennas syraadditionssalt |
| EP83105717A EP0096870B1 (en) | 1982-06-11 | 1983-06-10 | Ester of metronidazole with n,n-dimethylglycine and acid addition salt thereof |
| DE8383105717T DE3366566D1 (en) | 1982-06-11 | 1983-06-10 | Ester of metronidazole with n,n-dimethylglycine and acid addition salt thereof |
| AT83105717T ATE22558T1 (de) | 1982-06-11 | 1983-06-10 | Ester von metronidazol mit n,n-dimethylglycin und deren saeureadditionssalze. |
| NZ204530A NZ204530A (en) | 1982-06-11 | 1983-06-10 | A metronidazole ester |
| ES523174A ES523174A0 (es) | 1982-06-11 | 1983-06-10 | Procedimiento para preparar un ester de metronidazol. |
| CA000430125A CA1188305A (en) | 1982-06-11 | 1983-06-10 | Ester of metronidazole with n,n-dimethylglycine and acid addition salt thereof |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK264382 | 1982-06-11 | ||
| DK264382A DK147640C (da) | 1982-06-11 | 1982-06-11 | Fremgangsmaade til fremstilling af nitroimidazol-derivater |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK264382A true DK264382A (da) | 1983-12-12 |
| DK147640B DK147640B (da) | 1984-10-29 |
| DK147640C DK147640C (da) | 1985-05-06 |
Family
ID=8114115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK264382A DK147640C (da) | 1982-06-11 | 1982-06-11 | Fremgangsmaade til fremstilling af nitroimidazol-derivater |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4482722A (da) |
| EP (1) | EP0096870B1 (da) |
| JP (1) | JPS5925377A (da) |
| AT (1) | ATE22558T1 (da) |
| AU (1) | AU564952B2 (da) |
| CA (1) | CA1188305A (da) |
| DE (1) | DE3366566D1 (da) |
| DK (1) | DK147640C (da) |
| ES (1) | ES523174A0 (da) |
| FI (1) | FI832098L (da) |
| NO (1) | NO157619C (da) |
| NZ (1) | NZ204530A (da) |
| PT (1) | PT76844B (da) |
| ZA (1) | ZA834090B (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0127274A3 (en) * | 1983-03-25 | 1987-05-20 | The Upjohn Company | Esters of metronidazole and compositions containing them |
| US4943579A (en) * | 1987-10-06 | 1990-07-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Water soluble prodrugs of camptothecin |
| US6423707B1 (en) | 2000-08-28 | 2002-07-23 | California Pacific Medical Center | Nitroimidazole ester analogues and therapeutic applications |
| DE602004017214D1 (de) * | 2003-10-28 | 2008-11-27 | Ems Sa | Antibakterielle und/oder gegen protozoen wirksame nitroimidazolderivatverbindungen mit ureasehemmender wirkung, verfahren zur herstellung dieser verbindungen und deren verwendung in pharmazeutischen zusammensetzungen und medikamenten |
| US7244765B2 (en) * | 2004-06-25 | 2007-07-17 | Cytokine Pharmasciences, Inc | Guanylhydrazone salts, compositions, processes of making and methods of using |
| EP2749552B1 (en) | 2007-04-17 | 2015-11-18 | Codman & Shurtleff, Inc. | Curcumin-resveratrol hybrids |
| US8383865B2 (en) * | 2007-04-17 | 2013-02-26 | Codman & Shurtleff, Inc. | Curcumin derivatives |
| US7745670B2 (en) * | 2008-06-27 | 2010-06-29 | Codman & Shurtleff, Inc. | Curcumin-Resveratrol hybrid molecule |
| US7985776B2 (en) * | 2008-06-27 | 2011-07-26 | Codman & Shurtleff, Inc. | Iontophoretic delivery of curcumin and curcumin analogs for the treatment of Alzheimer's Disease |
| US7723515B1 (en) * | 2009-01-26 | 2010-05-25 | Codman & Shurtleff, Inc. | Methylene blue—curcumin analog for the treatment of alzheimer's disease |
| US20100286585A1 (en) * | 2009-01-26 | 2010-11-11 | Codman & Shurtleff, Inc. | Shunt Delivery of Curcumin |
| US20240285657A1 (en) * | 2023-02-28 | 2024-08-29 | Verte Therapeutics, LLC | Veterinary formulation of metronidazole, and related methods |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2944061A (en) * | 1957-09-20 | 1960-07-05 | Acyl derivatives and process | |
| US3803165A (en) * | 1972-08-14 | 1974-04-09 | Hoffmann La Roche | N-(2-(2-nitro-1-imidazolyl)ethyl)-2',2',2'-trichloroethyl carbamate |
-
1982
- 1982-06-11 DK DK264382A patent/DK147640C/da not_active IP Right Cessation
-
1983
- 1983-06-03 AU AU15365/83A patent/AU564952B2/en not_active Ceased
- 1983-06-06 ZA ZA834090A patent/ZA834090B/xx unknown
- 1983-06-08 US US06/502,210 patent/US4482722A/en not_active Expired - Fee Related
- 1983-06-09 PT PT76844A patent/PT76844B/pt unknown
- 1983-06-09 NO NO832089A patent/NO157619C/no unknown
- 1983-06-10 AT AT83105717T patent/ATE22558T1/de not_active IP Right Cessation
- 1983-06-10 NZ NZ204530A patent/NZ204530A/en unknown
- 1983-06-10 JP JP58104071A patent/JPS5925377A/ja active Pending
- 1983-06-10 EP EP83105717A patent/EP0096870B1/en not_active Expired
- 1983-06-10 FI FI832098A patent/FI832098L/fi not_active Application Discontinuation
- 1983-06-10 CA CA000430125A patent/CA1188305A/en not_active Expired
- 1983-06-10 ES ES523174A patent/ES523174A0/es active Granted
- 1983-06-10 DE DE8383105717T patent/DE3366566D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK147640B (da) | 1984-10-29 |
| CA1188305A (en) | 1985-06-04 |
| FI832098A7 (fi) | 1983-12-12 |
| FI832098A0 (fi) | 1983-06-10 |
| NO832089L (no) | 1983-12-12 |
| FI832098L (fi) | 1983-12-12 |
| DE3366566D1 (en) | 1986-11-06 |
| NO157619C (no) | 1988-04-20 |
| JPS5925377A (ja) | 1984-02-09 |
| ZA834090B (en) | 1984-02-29 |
| EP0096870B1 (en) | 1986-10-01 |
| PT76844A (en) | 1983-07-01 |
| DK147640C (da) | 1985-05-06 |
| AU564952B2 (en) | 1987-09-03 |
| ES8601149A1 (es) | 1985-11-01 |
| US4482722A (en) | 1984-11-13 |
| EP0096870A1 (en) | 1983-12-28 |
| NZ204530A (en) | 1986-05-09 |
| PT76844B (en) | 1986-01-15 |
| ATE22558T1 (de) | 1986-10-15 |
| NO157619B (no) | 1988-01-11 |
| ES523174A0 (es) | 1985-11-01 |
| AU1536583A (en) | 1983-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |