ES2546933T3 - Vacunas de subunidades contra el PRRSV - Google Patents

Vacunas de subunidades contra el PRRSV Download PDF

Info

Publication number
ES2546933T3
ES2546933T3 ES05766550.7T ES05766550T ES2546933T3 ES 2546933 T3 ES2546933 T3 ES 2546933T3 ES 05766550 T ES05766550 T ES 05766550T ES 2546933 T3 ES2546933 T3 ES 2546933T3
Authority
ES
Spain
Prior art keywords
prrsv
exposure
group
clones
vaccines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES05766550.7T
Other languages
English (en)
Spanish (es)
Inventor
Eric M. Vaughn
Richard Stammer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Animal Health USA Inc
Original Assignee
Boehringer Ingelheim Vetmedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Inc filed Critical Boehringer Ingelheim Vetmedica Inc
Application granted granted Critical
Publication of ES2546933T3 publication Critical patent/ES2546933T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10071Demonstrated in vivo effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES05766550.7T 2004-06-17 2005-06-17 Vacunas de subunidades contra el PRRSV Expired - Lifetime ES2546933T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US154617 1993-11-18
US58135004P 2004-06-17 2004-06-17
US581350P 2004-06-17
US11/154,617 US7722878B2 (en) 2004-06-17 2005-06-16 PRRSV subunit vaccines
PCT/US2005/021973 WO2006002193A2 (en) 2004-06-17 2005-06-17 Prrsv subunit vaccines

Publications (1)

Publication Number Publication Date
ES2546933T3 true ES2546933T3 (es) 2015-09-30

Family

ID=35431312

Family Applications (1)

Application Number Title Priority Date Filing Date
ES05766550.7T Expired - Lifetime ES2546933T3 (es) 2004-06-17 2005-06-17 Vacunas de subunidades contra el PRRSV

Country Status (14)

Country Link
US (1) US7722878B2 (enExample)
EP (1) EP1755664B1 (enExample)
JP (1) JP2008503221A (enExample)
KR (1) KR20070028431A (enExample)
AR (1) AR049825A1 (enExample)
AU (1) AU2005258092A1 (enExample)
BR (1) BRPI0510930A (enExample)
CA (1) CA2570778A1 (enExample)
DK (1) DK1755664T3 (enExample)
ES (1) ES2546933T3 (enExample)
MX (1) MXPA06014821A (enExample)
RU (1) RU2007101531A (enExample)
TW (1) TW200603825A (enExample)
WO (1) WO2006002193A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
PL204373B1 (pl) 1999-03-08 2010-01-29 Boehringer Ingelheim Vetemendi Replikony zespołu reprodukcyjnego i oddechowego świń (PRRSV), zastosowanie replikonów PRRSV, szczepionki zawierające replikony PRRSV i zastosowanie tych szczepionek
WO2000065032A1 (en) 1999-04-22 2000-11-02 United States Department Of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142
BRPI0510928A (pt) 2004-06-18 2007-11-13 Univ Minnesota identificação de organismos viralmente infectados e vacinados
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
CA3033206C (en) 2005-06-24 2021-10-19 Regents Of The University Of Minnesota Prrs viruses, infectious clones, mutants thereof, and methods of use
US8436337B2 (en) * 2009-05-12 2013-05-07 The State of Oregon Acting By and Through The State Board of Higher Education on Behalf of Oregon State Unitiversity Amorphous multi-component metallic thin films for electronic devices
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
UA112860C2 (uk) 2011-02-17 2016-11-10 Бьорінгер Інгельхайм Ветмедіка Гмбх Спосіб одержання prrsv у комерційному масштабі
CN103370078B (zh) 2011-02-17 2016-08-10 贝林格尔.英格海姆维特梅迪卡有限公司 新的欧洲型猪生殖与呼吸综合征病毒株
WO2012129176A1 (en) * 2011-03-18 2012-09-27 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Amorphous multi-component metal/metal oxide nanolaminate metamaterials and devices based thereon
EP2712927B1 (en) 2011-05-07 2019-08-21 Laboratorio Avi-Mex, S.A. De C.V. Recombinant vaccine against prrs in a viral vector
US9187731B2 (en) * 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
WO2014074360A1 (en) 2012-11-12 2014-05-15 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Amorphous metal thin-film non-linear resistor
US9579373B2 (en) 2013-03-15 2017-02-28 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
DK3591042T5 (da) 2013-12-20 2024-09-02 Boehringer Ingelheim Vetmedica Gmbh PRRS-virusvariant, cDNA-klon af europæisk PRRS-virus samt anvendelser deraf

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US20020012670A1 (en) * 2000-01-26 2002-01-31 Knut Elbers Recombinant attenuation of porcine reproductive and respiratory syndrome (PRRSV)
US6841364B2 (en) * 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof

Also Published As

Publication number Publication date
RU2007101531A (ru) 2008-07-27
CA2570778A1 (en) 2006-01-05
EP1755664B1 (en) 2015-06-10
WO2006002193A2 (en) 2006-01-05
EP1755664A2 (en) 2007-02-28
US20080038293A1 (en) 2008-02-14
JP2008503221A (ja) 2008-02-07
TW200603825A (en) 2006-02-01
AR049825A1 (es) 2006-09-06
US7722878B2 (en) 2010-05-25
DK1755664T3 (en) 2015-08-24
WO2006002193A3 (en) 2006-03-02
AU2005258092A1 (en) 2006-01-05
KR20070028431A (ko) 2007-03-12
BRPI0510930A (pt) 2007-11-20
MXPA06014821A (es) 2007-03-26

Similar Documents

Publication Publication Date Title
ES2546933T3 (es) Vacunas de subunidades contra el PRRSV
Lavelle et al. Mucosal vaccines—fortifying the frontiers
Plotkin History of vaccination
JP5779352B2 (ja) 複製欠損フラビウイルスワクチンおよびワクチンベクター
ES3017307T3 (en) Nucleic acid molecules and uses thereof
ES2251162T3 (es) Clon infeccioso con cdna de virus del sindrome reproductor y respiratorio porcino norteamericano (prrs) y sus usos.
JP5619004B2 (ja) 高病原性ブタ繁殖・呼吸障害症候群(hpprrs)のワクチン
TWI760322B (zh) 重組腺病毒載體裝載之fmdv疫苗及其用途
He et al. Induction of mucosal and systemic immune response by single-dose oral immunization with biodegradable microparticles containing DNA encoding HBsAg
US20110040079A1 (en) Infectious cDNA Clone of North American Porcine reproductive and Respiratory Syndrome (PRRS) Virus and Uses Thereof
PT835930E (pt) Estirpes europeias de vacina do virus do sindroma reprodutivo e respiratorio porcino (prrsv)
Gao et al. Porcine reproductive and respiratory syndrome virus expressing E2 of classical swine fever virus protects pigs from a lethal challenge of highly-pathogenic PRRSV and CSFV
BRPI0709282B1 (pt) vacina contra estreptococos
Renukaradhya et al. Mucosal vaccines to prevent porcine reproductive and respiratory syndrome: a new perspective
CA3029108A1 (en) Duck enteritis virus and the uses thereof
EP2408477A1 (en) Replication-defective flavivirus vaccine vectors against respiratory syncytial virus
Kim et al. Protection against very virulent infectious bursal disease virus in chickens immunized with DNA vaccines
Jiang et al. Humoral immune response induced by oral administration of S. typhimurium containing a DNA vaccine against porcine reproductive and respiratory syndrome virus
Comber et al. Gold nanoparticles (AuNPs): A new frontier in vaccine delivery
Mingxiao et al. Immunogenicity of plasmids encoding P12A and 3C of FMDV and swine IL-18
Koolaparambil Mukesh et al. Beyond COVID-19: the promise of next-generation coronavirus vaccines
ES2655190T3 (es) Prevención y tratamiento de la infección por Mycobacterium
KR20140105781A (ko) 신규한 약독화된 폴리오바이러스: pv-1 모노-cre-x
Yu et al. Priming with CpG-enriched plasmid and boosting with protein formulated with CpG oligodeoxynucleotides and Quil A induces strong cellular and humoral immune responses to hepatitis C virus NS3
Chary et al. Protection by recombinant viral proteins against a respiratory challenge with virulent avian metapneumovirus