BRPI0510930A - vacinas de subunidade de prrsv - Google Patents

vacinas de subunidade de prrsv

Info

Publication number
BRPI0510930A
BRPI0510930A BRPI0510930-2A BRPI0510930A BRPI0510930A BR PI0510930 A BRPI0510930 A BR PI0510930A BR PI0510930 A BRPI0510930 A BR PI0510930A BR PI0510930 A BRPI0510930 A BR PI0510930A
Authority
BR
Brazil
Prior art keywords
prrsv
vaccines
combination
subunit vaccines
orf1
Prior art date
Application number
BRPI0510930-2A
Other languages
English (en)
Inventor
Eric M Vaughn
Richard Stammer
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Publication of BRPI0510930A publication Critical patent/BRPI0510930A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10071—Demonstrated in vivo effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

VACINAS DE SUBUNIDADE DE PRRSV A presente invenção refere-se a vacinas eficazes contra PRRSV incluem pelo menos uma porção de ORF1 de PRRSV. Tais vacinas, mediante administração, provocam uma resposta imune em animais suscetíveis ao PRRSV. Além disso, composições de acordo com a presente invenção fornecem resposta imune até e incluindo imunidade protetora contra PRRSV assim como reduzem a severidade de PRRSV e/ou a incidência de PRRSV. Porções selecionadas de ORF1 podem ser usadas isoladamente, em combinação uma com a outra, em combinação com outras ORFs de PRRSV e em combinação com outras vacinas de PRRSV.
BRPI0510930-2A 2004-06-17 2005-06-17 vacinas de subunidade de prrsv BRPI0510930A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58135004P 2004-06-17 2004-06-17
US11/154,617 US7722878B2 (en) 2004-06-17 2005-06-16 PRRSV subunit vaccines
PCT/US2005/021973 WO2006002193A2 (en) 2004-06-17 2005-06-17 Prrsv subunit vaccines

Publications (1)

Publication Number Publication Date
BRPI0510930A true BRPI0510930A (pt) 2007-11-20

Family

ID=35431312

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510930-2A BRPI0510930A (pt) 2004-06-17 2005-06-17 vacinas de subunidade de prrsv

Country Status (14)

Country Link
US (1) US7722878B2 (pt)
EP (1) EP1755664B1 (pt)
JP (1) JP2008503221A (pt)
KR (1) KR20070028431A (pt)
AR (1) AR049825A1 (pt)
AU (1) AU2005258092A1 (pt)
BR (1) BRPI0510930A (pt)
CA (1) CA2570778A1 (pt)
DK (1) DK1755664T3 (pt)
ES (1) ES2546933T3 (pt)
MX (1) MXPA06014821A (pt)
RU (1) RU2007101531A (pt)
TW (1) TW200603825A (pt)
WO (1) WO2006002193A2 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053787A1 (en) 1999-03-08 2000-09-14 Id-Lelystad, Instituut Voor Dierhouderij En Dierg Ezondheid B.V. Prrsv vaccines
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
DK1183332T3 (da) 1999-04-22 2010-09-06 Us Agriculture Porcint Reproduktions- og Respirations Syndrom-vaccine baseret på isolere JA-142
BRPI0510928A (pt) 2004-06-18 2007-11-13 Univ Minnesota identificação de organismos viralmente infectados e vacinados
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
UA95778C2 (ru) 2005-06-24 2011-09-12 Риджентс Оф Зе Юниверсити Оф Миннесота Вирусы репродуктивно-респираторного синдрома свиней, их инфекционные клоны и мутанты и способы применения
US8436337B2 (en) 2009-05-12 2013-05-07 The State of Oregon Acting By and Through The State Board of Higher Education on Behalf of Oregon State Unitiversity Amorphous multi-component metallic thin films for electronic devices
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
WO2012110490A1 (en) 2011-02-17 2012-08-23 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of prrsv
MY186535A (en) 2011-02-17 2021-07-26 Boehringer Ingelheim Vetmedica Gmbh Novel european prrsv strain
US20140302310A1 (en) * 2011-03-18 2014-10-09 The State of Oregon Acting by and Through the State Board of Higher Education on Behalf of Or... Amorphous multi-component metal/metal oxide nanolaminate metamaterials and devices based thereon
BR112013028605A2 (pt) 2011-05-07 2017-01-17 Avi Mex S A De C V Lab vetor viral, vacina recombinante contra prrs e uso de uma vacina
US9187731B2 (en) * 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
US9315781B2 (en) 2011-07-29 2016-04-19 Boehringer Ingelheim Vetmedica Gmbh Infectious CDNA clone of european PRRS virus and uses thereof
CN105264618B (zh) 2012-11-12 2018-06-05 俄勒冈州立大学 非晶金属薄膜非线性电阻器
EP2968513A2 (en) 2013-03-15 2016-01-20 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
DK3083947T3 (da) 2013-12-20 2019-07-08 Boehringer Ingelheim Vetmedica Gmbh Prrs-virusvariant, cdna-klon af europæisk prrs-virus, samt anvendelser deraf

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US20020012670A1 (en) * 2000-01-26 2002-01-31 Knut Elbers Recombinant attenuation of porcine reproductive and respiratory syndrome (PRRSV)
US6841364B2 (en) * 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof

Also Published As

Publication number Publication date
TW200603825A (en) 2006-02-01
AU2005258092A1 (en) 2006-01-05
RU2007101531A (ru) 2008-07-27
MXPA06014821A (es) 2007-03-26
US7722878B2 (en) 2010-05-25
CA2570778A1 (en) 2006-01-05
WO2006002193A2 (en) 2006-01-05
KR20070028431A (ko) 2007-03-12
DK1755664T3 (en) 2015-08-24
WO2006002193A3 (en) 2006-03-02
US20080038293A1 (en) 2008-02-14
ES2546933T3 (es) 2015-09-30
AR049825A1 (es) 2006-09-06
EP1755664B1 (en) 2015-06-10
EP1755664A2 (en) 2007-02-28
JP2008503221A (ja) 2008-02-07

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]