ES2541726T3 - Anticuerpos anti-Notch2 y métodos de uso - Google Patents
Anticuerpos anti-Notch2 y métodos de uso Download PDFInfo
- Publication number
- ES2541726T3 ES2541726T3 ES09793181.0T ES09793181T ES2541726T3 ES 2541726 T3 ES2541726 T3 ES 2541726T3 ES 09793181 T ES09793181 T ES 09793181T ES 2541726 T3 ES2541726 T3 ES 2541726T3
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3053—Skin, nerves, brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10191708P | 2008-10-01 | 2008-10-01 | |
| US101917P | 2008-10-01 | ||
| PCT/US2009/059028 WO2010039832A1 (en) | 2008-10-01 | 2009-09-30 | Anti-notch2 antibodies and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2541726T3 true ES2541726T3 (es) | 2015-07-23 |
Family
ID=41349057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09793181.0T Active ES2541726T3 (es) | 2008-10-01 | 2009-09-30 | Anticuerpos anti-Notch2 y métodos de uso |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US8404239B2 (show.php) |
| EP (1) | EP2334331B1 (show.php) |
| JP (2) | JP5710487B2 (show.php) |
| KR (1) | KR101712214B1 (show.php) |
| CN (1) | CN102170909B (show.php) |
| AR (1) | AR073717A1 (show.php) |
| AU (1) | AU2009298569A1 (show.php) |
| BR (1) | BRPI0913827A2 (show.php) |
| CA (1) | CA2736429A1 (show.php) |
| CL (1) | CL2011000711A1 (show.php) |
| ES (1) | ES2541726T3 (show.php) |
| IL (1) | IL211623A0 (show.php) |
| MX (1) | MX2011002928A (show.php) |
| PE (1) | PE20120080A1 (show.php) |
| RU (1) | RU2580029C2 (show.php) |
| TW (1) | TW201018484A (show.php) |
| WO (1) | WO2010039832A1 (show.php) |
| ZA (1) | ZA201101651B (show.php) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2032166T3 (pl) | 2006-06-13 | 2013-09-30 | Oncomed Pharm Inc | Kompozycje i sposoby diagnozowania i leczenia nowotworów |
| US8088617B2 (en) | 2007-01-24 | 2012-01-03 | Oncomed Pharmaceuticals, Inc. | Antibodies that bind the glutamate ligand binding region of Notch1 |
| NZ590127A (en) | 2008-07-08 | 2012-11-30 | Oncomed Pharm Inc | Notch1 receptor binding agents and methods of use thereof |
| US9132189B2 (en) | 2008-07-08 | 2015-09-15 | Oncomed Pharmaceuticals, Inc. | Notch1 binding agents and methods of use thereof |
| ES2541726T3 (es) * | 2008-10-01 | 2015-07-23 | F. Hoffmann-La Roche Ag | Anticuerpos anti-Notch2 y métodos de uso |
| CA2812389C (en) | 2010-09-27 | 2019-12-31 | John Kehoe | Antibodies binding human collagen ii |
| US8906649B2 (en) | 2010-09-27 | 2014-12-09 | Janssen Biotech, Inc. | Antibodies binding human collagen II |
| WO2013052155A1 (en) * | 2011-10-05 | 2013-04-11 | Genentech, Inc. | Methods of treating liver conditions using notch2 antagonists |
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- 2009-09-30 WO PCT/US2009/059028 patent/WO2010039832A1/en not_active Ceased
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| KR20110061600A (ko) | 2011-06-09 |
| US20140314782A1 (en) | 2014-10-23 |
| MX2011002928A (es) | 2011-04-11 |
| US20180057589A1 (en) | 2018-03-01 |
| AU2009298569A1 (en) | 2010-04-08 |
| EP2334331A1 (en) | 2011-06-22 |
| EP2334331B1 (en) | 2015-04-29 |
| US20140037643A1 (en) | 2014-02-06 |
| RU2011117237A (ru) | 2012-11-10 |
| RU2580029C2 (ru) | 2016-04-10 |
| JP5710487B2 (ja) | 2015-04-30 |
| ZA201101651B (en) | 2012-06-27 |
| TW201018484A (en) | 2010-05-16 |
| BRPI0913827A2 (pt) | 2020-12-29 |
| US20100080808A1 (en) | 2010-04-01 |
| CA2736429A1 (en) | 2010-04-08 |
| CL2011000711A1 (es) | 2012-07-20 |
| JP2012504634A (ja) | 2012-02-23 |
| PE20120080A1 (es) | 2012-02-17 |
| AR073717A1 (es) | 2010-11-24 |
| US8404239B2 (en) | 2013-03-26 |
| KR101712214B1 (ko) | 2017-03-03 |
| CN102170909B (zh) | 2015-11-25 |
| JP2015145379A (ja) | 2015-08-13 |
| IL211623A0 (en) | 2011-05-31 |
| WO2010039832A1 (en) | 2010-04-08 |
| CN102170909A (zh) | 2011-08-31 |
| US20170204175A9 (en) | 2017-07-20 |
| US20150104461A1 (en) | 2015-04-16 |
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