ES2539310T3 - Composiciones bucosolubles que contienen al menos una sal de S-adenosilmetionina (SAMe) - Google Patents

Composiciones bucosolubles que contienen al menos una sal de S-adenosilmetionina (SAMe) Download PDF

Info

Publication number
ES2539310T3
ES2539310T3 ES10703355.7T ES10703355T ES2539310T3 ES 2539310 T3 ES2539310 T3 ES 2539310T3 ES 10703355 T ES10703355 T ES 10703355T ES 2539310 T3 ES2539310 T3 ES 2539310T3
Authority
ES
Spain
Prior art keywords
same
composition according
bucosoluble
acid
lactobacillus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10703355.7T
Other languages
English (en)
Spanish (es)
Inventor
Alessandro Seneci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Graal Srl
Original Assignee
Graal Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Graal Srl filed Critical Graal Srl
Application granted granted Critical
Publication of ES2539310T3 publication Critical patent/ES2539310T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
ES10703355.7T 2009-02-09 2010-01-11 Composiciones bucosolubles que contienen al menos una sal de S-adenosilmetionina (SAMe) Active ES2539310T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
ITMI20090162 2009-02-09
ITMI2009A000162A IT1393331B1 (it) 2009-02-09 2009-02-09 Composizioni orosolubili e/o effervescenti contenenti almeno un sale di s-adenosilmetionina (same)
US21955309P 2009-06-23 2009-06-23
US219553P 2009-06-23
PCT/IB2010/050087 WO2010089674A1 (en) 2009-02-09 2010-01-11 Orosoluble and/or effervescent compositions containing at least a salt of s- adenosyl methionine (same)

Publications (1)

Publication Number Publication Date
ES2539310T3 true ES2539310T3 (es) 2015-06-29

Family

ID=40995758

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10703355.7T Active ES2539310T3 (es) 2009-02-09 2010-01-11 Composiciones bucosolubles que contienen al menos una sal de S-adenosilmetionina (SAMe)

Country Status (13)

Country Link
US (1) US10149821B2 (ru)
EP (1) EP2393475B1 (ru)
AU (1) AU2010212042A1 (ru)
BR (1) BRPI1008213A2 (ru)
CA (1) CA2752009C (ru)
DK (1) DK2393475T3 (ru)
ES (1) ES2539310T3 (ru)
IL (1) IL213817A0 (ru)
IT (1) IT1393331B1 (ru)
PL (1) PL2393475T3 (ru)
PT (1) PT2393475E (ru)
RU (1) RU2524645C2 (ru)
WO (1) WO2010089674A1 (ru)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2963239B1 (fr) * 2010-08-02 2013-03-08 Vetalis Formes galeniques effervescentes solides pour animaux
KR101645619B1 (ko) 2011-08-12 2016-08-05 미쯔비시 가스 케미칼 컴파니, 인코포레이티드 보존안정성이 우수한 s-아데노실-l-메티오닌 함유 조성물
US8877259B2 (en) 2012-02-09 2014-11-04 Mary Kay Inc. Cosmetic formulation
CN104418928B (zh) * 2013-08-27 2017-03-29 上海医药工业研究院 一种1,4‑丁二磺酸腺苷蛋氨酸的制备方法
US9351921B1 (en) * 2013-09-10 2016-05-31 Spa De Soleil, Inc. Microdermabrasion cream
AT14825U1 (de) * 2014-11-10 2016-07-15 Eduard Rappold Kombinationspräparat enthaltend Ademetionin und Vitamin B12 zur Behandlung und Prävention der Alzheimer-Krankheit Typ I (LOAD)
ES2586632B1 (es) * 2015-01-29 2017-09-05 Wug Functional Gums, S.L Composición para elaborar chicles
US9446100B2 (en) 2015-02-13 2016-09-20 Eastern Vision Limited Dietary supplements and formulations
CN104983026A (zh) * 2015-07-21 2015-10-21 上海海洋大学 山楂泡腾片及其制备方法
ES2775734T3 (es) * 2015-08-31 2020-07-28 Nutramax Lab Inc Composiciones que comprenden magnolia, felodendron, teanina y/o proteína de suero
RU2611411C1 (ru) * 2016-01-11 2017-02-21 Общество с ограниченной ответственностью "Трейдсервис" Диспергируемая в воде таблетка ацетилцистеина и способ ее изготовления
ITUA20163269A1 (it) 2016-05-09 2017-11-09 Graal S R L Composizione ad assorbimento orobuccale per la neuro-protezione
IT201600080839A1 (it) * 2016-08-01 2018-02-01 Esserre Pharma Srl Composizione a base di S-Adenosil-L-Metionina e Melatonina per il trattamento dei disturbi del comportamento alimentare
US10881686B2 (en) * 2017-10-27 2021-01-05 Zeta Biolongevity, Inc Compositions and methods for treating and preventing proteinuria and endothelial erosion
IT201900015192A1 (it) 2019-08-29 2021-03-01 Graal S R L Formulazioni edibili a base di principi attivi e arginina
CN111172043B (zh) * 2020-01-14 2021-03-05 北京工商大学 一种提高紫红曲霉中红曲色素合成的发酵方法
IT202000006127A1 (it) * 2020-03-23 2021-09-23 Fmc S R L Formulazione farmaceutica, dietetica e/o alimentare a base ademetionina e processo di realizzazione di detta formulazione
CN111297963B (zh) * 2020-04-10 2021-11-26 广东轻工职业技术学院 一种解酒护肝提取物、组合物及制备方法与应用
IT202000008482A1 (it) * 2020-04-21 2021-10-21 Montefarmaco Otc S P A Composizione orale contente s-adenosil metionina (same) e almeno un probiotico e suo uso
RU2749833C1 (ru) * 2020-08-11 2021-06-17 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет технологий и управления имени К.Г. Разумовского (ПКУ)" Способ производства диетического витаминизированного шоколада
IT202000030914A1 (it) * 2020-12-15 2022-06-15 Mario Antonio Basile Composizione farmaceutica solida di ademetionina e cannabidiolo e procedimento per ottenerla
WO2023228167A2 (en) * 2023-09-04 2023-11-30 Carlo De Angelis Solid food or pharmaceutical formulation, methods for obtaining and drying it and its uses in pharmaceutical, nutraceutical or veterinary products

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4057672A (en) 1973-05-29 1977-11-08 The Goodyear Tire & Rubber Company Compounded polyvinyl chloride
IE39517B1 (en) * 1973-06-27 1978-10-25 Bioresearch Sas Double salts of s-adenosyl-l-methhionine
US4432975A (en) * 1981-04-13 1984-02-21 Icn Pharmaceuticals, Inc. Process for introducing vitamin B-12 into the bloodstream
IT1137640B (it) 1981-08-24 1986-09-10 Bioresearch Srl Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
EP0893992B1 (en) * 1996-04-16 2004-03-03 Novartis Consumer Health S.A. Fast disintegrating oral dosage form
BRPI0515932A (pt) * 2004-10-15 2008-08-12 Pfizer Prod Inc composições e métodos para distribuição intranasal, bucal, sublingual e pulmonar de vareniclina
US20060127506A1 (en) * 2004-12-10 2006-06-15 Hebert Rolland F Compositions of S-adenosyl-L-methionine
US20060198885A1 (en) * 2005-02-22 2006-09-07 Sun Pharmaceutical Industries Ltd. Oral pharmaceutical composition
ITRM20050344A1 (it) * 2005-06-30 2007-01-01 Luca Maria De Sali o complessi di sostanze metil-donatrici con acido fitico o suoi derivati e relativo metodo di sintesi.
ITMI20060026A1 (it) * 2006-01-10 2007-07-11 Truffini & Regge Farmaceutici Srl Composizioni per uso rale a base di s-adenosilmetionina e processo per il loro ottenimento
RU2313349C2 (ru) * 2006-01-16 2007-12-27 Михаил Аркадьевич Шурдов Способ лечения онкологических заболеваний
ITMI20060629A1 (it) * 2006-03-31 2007-10-01 Daniele Giovannone Composizioni solide orali a base di s-adenosilmetionina e processo per il loro ottenimento
US8597640B2 (en) * 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
EP2189154A1 (en) * 2008-11-25 2010-05-26 Gnosis S.p.A. Effervescent tablets and mouth-soluble granulates of S-adenosyl methionine and process for the preparation thereof
EP2193787A1 (en) * 2008-12-02 2010-06-09 Giorgio Stramentinoli Formulations for systemic buccal delivery comprising s-adenosylmethionine, their preparation and use

Also Published As

Publication number Publication date
EP2393475A1 (en) 2011-12-14
US20110300081A1 (en) 2011-12-08
RU2524645C2 (ru) 2014-07-27
WO2010089674A1 (en) 2010-08-12
CA2752009A1 (en) 2010-08-12
BRPI1008213A2 (pt) 2016-03-15
DK2393475T3 (en) 2015-06-15
RU2011137151A (ru) 2013-03-20
ITMI20090162A1 (it) 2010-08-10
AU2010212042A1 (en) 2011-07-21
PT2393475E (pt) 2015-07-17
PL2393475T3 (pl) 2015-08-31
CA2752009C (en) 2016-09-27
AU2010212042A2 (en) 2011-08-18
US10149821B2 (en) 2018-12-11
IT1393331B1 (it) 2012-04-20
IL213817A0 (en) 2011-07-31
EP2393475B1 (en) 2015-03-11

Similar Documents

Publication Publication Date Title
ES2539310T3 (es) Composiciones bucosolubles que contienen al menos una sal de S-adenosilmetionina (SAMe)
ES2680638T3 (es) Gránulos efervescentes de ácido gamma-hidroxibutírico
ES2397746T3 (es) Métodos de administración de tetrahidrobiopterina, composiciones asociadas y métodos de medición
ES2324907T3 (es) Procedimiento para la fabricacion de comprimidos analgesicos que comprenden un par efervescente para su administracion a traves de la mucosa oral.
ES2345067T3 (es) Metodo para usar extracto de guayaba y composicion que incluye extracto de guayaba.
ES2549224T3 (es) Formulaciones orales de película que comprenden dapoxetina y tadalafilo
US20110014132A1 (en) Solid effervescent mixture for the oral absorption
ES2525163T3 (es) Método para preparar composiciones farmacéuticas pretendidas para administración oral que comprenden uno o más ingredientes activos y las composiciones que comprenden los mismos
ES2369589T3 (es) Pellas recubiertas.
RU2009146576A (ru) Никотиновая композиция для перорального применения, содержащая аминокислотный буфер
KR101203186B1 (ko) 약물의 맛이 차폐된 경구용 약학 조성물 및 그 제조 방법
ES2736183T3 (es) Composición de absorción oro-bucal para neuro-protector
ES2635763T3 (es) Composición de complemento nutricional
WO2004078171A1 (ja) 吸水性アミノ酸含有錠剤
JP2004242509A (ja) コエンザイムｑ１０およびアミノ酸類を含有する食品
US20160000716A1 (en) Method of treating vitamin b12 deficiency
US11213505B2 (en) Product based on iron bis-glycinate chelate and alginic acid and/or water-soluble salts thereof, formulations thereof, and pharmaceutical uses thereof
ES2457718B1 (es) Composición farmacéutica bucodispersable de melatonina
EP2698148A1 (en) Chewing Gum Formulations Comprising Dapoxetine and Tadalafil
IT201900015192A1 (it) Formulazioni edibili a base di principi attivi e arginina
KR20140122017A (ko) 엔테카비르 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 속붕해성 제제 및 이의 제조방법
JP2011068614A (ja) ビタミン製剤
TR2021001998A2 (tr) Pelargoni̇um türleri̇ni̇ i̇çeren bi̇r efervesan bi̇leşi̇m
JP2022170891A (ja) 経口固形製剤
ES2383478T3 (es) Comprimido para administración bucal, sublingual o gingival que comprende un aditivo efervescente