ES2523401T3 - Intermedios de un nuevo procedimiento para la preparación de derivados de 5-benciliden-2-alquilimino-3- feniltiazolidin-4-ona - Google Patents
Intermedios de un nuevo procedimiento para la preparación de derivados de 5-benciliden-2-alquilimino-3- feniltiazolidin-4-ona Download PDFInfo
- Publication number
- ES2523401T3 ES2523401T3 ES12000613.5T ES12000613T ES2523401T3 ES 2523401 T3 ES2523401 T3 ES 2523401T3 ES 12000613 T ES12000613 T ES 12000613T ES 2523401 T3 ES2523401 T3 ES 2523401T3
- Authority
- ES
- Spain
- Prior art keywords
- hydroxy
- thiazolidin
- benc
- iliden
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/54—Nitrogen and either oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| WOPCT/IB2006/054409 | 2006-11-23 | ||
| IB2006054409 | 2006-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2523401T3 true ES2523401T3 (es) | 2014-11-25 |
Family
ID=39316391
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12000613.5T Active ES2523401T3 (es) | 2006-11-23 | 2007-11-22 | Intermedios de un nuevo procedimiento para la preparación de derivados de 5-benciliden-2-alquilimino-3- feniltiazolidin-4-ona |
| ES07849225T Active ES2410793T3 (es) | 2006-11-23 | 2007-11-22 | Nuevo procedimiento para la preparación de derivados de 2-imino-tiazolidin-4-ona |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07849225T Active ES2410793T3 (es) | 2006-11-23 | 2007-11-22 | Nuevo procedimiento para la preparación de derivados de 2-imino-tiazolidin-4-ona |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8263780B2 (https=) |
| EP (2) | EP2094676B1 (https=) |
| JP (1) | JP4669564B2 (https=) |
| KR (1) | KR101255879B1 (https=) |
| CN (2) | CN101541772B (https=) |
| AU (1) | AU2007323042B2 (https=) |
| CA (1) | CA2669069C (https=) |
| DK (2) | DK2094676T3 (https=) |
| ES (2) | ES2523401T3 (https=) |
| IL (1) | IL198847A (https=) |
| MX (1) | MX2009005048A (https=) |
| TW (1) | TWI460166B (https=) |
| WO (1) | WO2008062376A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE43728E1 (en) | 2003-11-21 | 2012-10-09 | Actelion Pharmaceuticals Ltd. | Thiazolidin-4-one derivatives |
| USRE43833E1 (en) | 2003-11-21 | 2012-11-27 | Actelion Pharmaceuticals Ltd. | Thiazolidin-4-one derivatives |
| US8912340B2 (en) | 2006-11-23 | 2014-12-16 | Actelion Pharmaceuticals Ltd. | Process for the preparation of 2-imino-thiazolidin-4-one derivatives |
| PL2278960T5 (pl) | 2008-03-17 | 2020-06-29 | Actelion Pharmaceuticals Ltd. | Schemat dawkowania dla selektywnego agonisty receptora sip1 |
| GB0819182D0 (en) | 2008-10-20 | 2008-11-26 | Actelion Pharmaceuticals Ltd | Crystalline forms |
| SMT202000298T1 (it) * | 2012-08-17 | 2020-07-08 | Actelion Pharmaceuticals Ltd | Processo per la produzione di (2z,5z)-5-(3-cloro-4((r)-2,3-diidrossipropossi) benziliden)-2-(propilimmino)-3-(o-tolil)tiazolidin-4-one e intermedio usato in detto processo |
| MA41139B1 (fr) | 2014-12-11 | 2026-02-27 | Laboratoires Juvise Pharmaceuticals | Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque |
| KR20200013086A (ko) | 2014-12-11 | 2020-02-05 | 액테리온 파마슈티칼 리미티드 | 선택적 s1p1 수용체 효능제에 대한 투약 섭생 |
| JOP20190207A1 (ar) | 2017-03-14 | 2019-09-10 | Actelion Pharmaceuticals Ltd | تركيبة صيدلانية تشتمل على بونيسيمود |
| EP3684358A4 (en) | 2017-09-19 | 2021-01-13 | Teva Pharmaceuticals International GmbH | NEW CRYSTALLINE POLYMORPHIC SHAPE OF PONESIMOD |
| US11186556B1 (en) | 2018-10-16 | 2021-11-30 | Celgene Corporation | Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof |
| US11014897B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof |
| US11014940B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Thiazolidinone and oxazolidinone compounds and formulations |
| US11013723B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Solid forms of a thiazolidinone compound, compositions and methods of use thereof |
| KR20220034151A (ko) * | 2019-07-10 | 2022-03-17 | 바이엘 악티엔게젤샤프트 | 2-(페닐이미노)-1,3-티아졸리딘-4-온의 제조 방법 |
| BR112022000185A2 (pt) * | 2019-07-10 | 2022-02-22 | Bayer Ag | Método de preparação de 2-(fenilimino)-1,3-tiazolidin-4-onas |
| JP7749552B2 (ja) | 2019-10-31 | 2025-10-06 | イドルシア・ファーマシューティカルズ・リミテッド | Ｃｘｃｒ７アンタゴニストのｓ１ｐ１受容体調節剤との合剤 |
| KR20200019639A (ko) | 2020-01-30 | 2020-02-24 | 전대연 | 만남의 스마트 도착시스템 |
| IL295464A (en) * | 2020-02-18 | 2022-10-01 | Bayer Ag | Process of preparing 2-(phenylimino)-3-alkyl-1,3-thiazolidin-4-ones |
| EP4387960A1 (en) | 2021-08-17 | 2024-06-26 | Teva Czech Industries s.r.o | Polymorphs of ponesimod |
| EP4212156A1 (en) | 2022-01-13 | 2023-07-19 | Abivax | Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator |
| WO2023152691A1 (en) * | 2022-02-10 | 2023-08-17 | Metrochem Api Pvt Ltd | Process for the preparation of ponesimod and its intermediates thereof |
| CN117924210B (zh) * | 2024-01-22 | 2026-04-03 | 赣南师范大学 | 一种2-亚氨基噻唑烷-4-酮类化合物的制备方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3077402A (en) * | 1954-12-06 | 1963-02-12 | Polaroid Corp | Photographic color processes, products, and compositions |
| NL270002A (https=) | 1960-10-08 | |||
| OA03835A (fr) * | 1970-07-17 | 1971-12-24 | Rhone Poulenc Sa | Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent. |
| PT97507B (pt) | 1990-04-27 | 1998-08-31 | Orion Yhtymae Oy | Processo para apreparacao de novos derivados de catecol farmacologicamente activos |
| TW221689B (https=) * | 1991-08-27 | 1994-03-11 | Otsuka Pharma Co Ltd | |
| EP0638075B1 (en) * | 1993-02-26 | 2002-01-16 | Otsuka Pharmaceutical Co., Ltd. | Thiazole or imidazole derivatives as maillard reaction inhibitors |
| KR960022486A (ko) | 1994-12-29 | 1996-07-18 | 김준웅 | 신규 티아졸리딘-4-온 유도체 |
| WO2001036402A1 (en) * | 1998-07-14 | 2001-05-25 | Fujimoto Brothers Co., Ltd. | Novel 2-(n-cyanoimino)thiazolidin-4-one derivatives |
| US6353006B1 (en) * | 1999-01-14 | 2002-03-05 | Bayer Corporation | Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents |
| CN1247553C (zh) | 1999-09-14 | 2006-03-29 | 盐野义制药株式会社 | 2－亚氨基－1,3－噻嗪衍生物 |
| US20050019825A9 (en) * | 2002-03-15 | 2005-01-27 | Qing Dong | Common ligand mimics: pseudothiohydantoins |
| JP4782564B2 (ja) | 2002-07-10 | 2011-09-28 | メルク セローノ ソシエテ アノニム | アゾリジノン−ビニル縮合−ベンゼン誘導体 |
| GB0217152D0 (en) | 2002-07-24 | 2002-09-04 | Novartis Ag | Organic compounds |
| CN100579978C (zh) * | 2002-11-22 | 2010-01-13 | 史密丝克莱恩比彻姆公司 | 化合物 |
| US20040167192A1 (en) | 2003-01-16 | 2004-08-26 | David Solow-Cordero | Methods of treating conditions associated with an Edg-7 receptor |
| USRE43728E1 (en) | 2003-11-21 | 2012-10-09 | Actelion Pharmaceuticals Ltd. | Thiazolidin-4-one derivatives |
| EP1718642A4 (en) * | 2004-02-25 | 2010-11-24 | Glaxosmithkline Llc | NEW CHEMICAL COMPOUNDS |
| WO2006094233A1 (en) * | 2005-03-03 | 2006-09-08 | Sirtris Pharmaceuticals, Inc. | N,n'-dicyclic isothiourea sirtuin modulators |
| PL2278960T5 (pl) | 2008-03-17 | 2020-06-29 | Actelion Pharmaceuticals Ltd. | Schemat dawkowania dla selektywnego agonisty receptora sip1 |
| GB0819182D0 (en) | 2008-10-20 | 2008-11-26 | Actelion Pharmaceuticals Ltd | Crystalline forms |
-
2007
- 2007-11-22 TW TW096144311A patent/TWI460166B/zh active
- 2007-11-22 ES ES12000613.5T patent/ES2523401T3/es active Active
- 2007-11-22 DK DK07849225.3T patent/DK2094676T3/da active
- 2007-11-22 JP JP2009537744A patent/JP4669564B2/ja active Active
- 2007-11-22 DK DK12000613.5T patent/DK2489662T3/da active
- 2007-11-22 EP EP07849225.3A patent/EP2094676B1/en active Active
- 2007-11-22 AU AU2007323042A patent/AU2007323042B2/en active Active
- 2007-11-22 US US12/516,055 patent/US8263780B2/en active Active
- 2007-11-22 ES ES07849225T patent/ES2410793T3/es active Active
- 2007-11-22 KR KR1020097011745A patent/KR101255879B1/ko active Active
- 2007-11-22 CA CA2669069A patent/CA2669069C/en active Active
- 2007-11-22 CN CN2007800431941A patent/CN101541772B/zh active Active
- 2007-11-22 WO PCT/IB2007/054752 patent/WO2008062376A2/en not_active Ceased
- 2007-11-22 CN CN2012105461683A patent/CN103087004A/zh active Pending
- 2007-11-22 EP EP12000613.5A patent/EP2489662B1/en active Active
- 2007-11-22 MX MX2009005048A patent/MX2009005048A/es active IP Right Grant
-
2009
- 2009-05-20 IL IL198847A patent/IL198847A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP2489662B1 (en) | 2014-08-06 |
| TWI460166B (zh) | 2014-11-11 |
| EP2489662A1 (en) | 2012-08-22 |
| JP2010510976A (ja) | 2010-04-08 |
| CA2669069C (en) | 2015-02-17 |
| KR101255879B1 (ko) | 2013-04-17 |
| CN101541772B (zh) | 2013-04-17 |
| KR20090081009A (ko) | 2009-07-27 |
| AU2007323042B2 (en) | 2012-12-20 |
| US8263780B2 (en) | 2012-09-11 |
| US20110201821A2 (en) | 2011-08-18 |
| US20100317867A1 (en) | 2010-12-16 |
| CN101541772A (zh) | 2009-09-23 |
| AU2007323042A1 (en) | 2008-05-29 |
| MX2009005048A (es) | 2009-05-25 |
| CA2669069A1 (en) | 2008-05-29 |
| DK2489662T3 (da) | 2014-10-20 |
| JP4669564B2 (ja) | 2011-04-13 |
| WO2008062376A2 (en) | 2008-05-29 |
| EP2094676B1 (en) | 2013-04-10 |
| CN103087004A (zh) | 2013-05-08 |
| DK2094676T3 (da) | 2013-06-10 |
| TW200831474A (en) | 2008-08-01 |
| IL198847A (en) | 2015-07-30 |
| ES2410793T3 (es) | 2013-07-03 |
| IL198847A0 (en) | 2010-02-17 |
| WO2008062376A3 (en) | 2008-07-10 |
| EP2094676A2 (en) | 2009-09-02 |
| BRPI0718986A2 (pt) | 2014-02-11 |
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