ES2523401T3 - Intermedios de un nuevo procedimiento para la preparación de derivados de 5-benciliden-2-alquilimino-3- feniltiazolidin-4-ona - Google Patents

Intermedios de un nuevo procedimiento para la preparación de derivados de 5-benciliden-2-alquilimino-3- feniltiazolidin-4-ona Download PDF

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Publication number
ES2523401T3
ES2523401T3 ES12000613.5T ES12000613T ES2523401T3 ES 2523401 T3 ES2523401 T3 ES 2523401T3 ES 12000613 T ES12000613 T ES 12000613T ES 2523401 T3 ES2523401 T3 ES 2523401T3
Authority
ES
Spain
Prior art keywords
hydroxy
thiazolidin
benc
iliden
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12000613.5T
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English (en)
Spanish (es)
Inventor
Stefan Abele
Martin Bolli
Gunther Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Actelion Pharmaceuticals Ltd
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Application granted granted Critical
Publication of ES2523401T3 publication Critical patent/ES2523401T3/es
Active legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES12000613.5T 2006-11-23 2007-11-22 Intermedios de un nuevo procedimiento para la preparación de derivados de 5-benciliden-2-alquilimino-3- feniltiazolidin-4-ona Active ES2523401T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
WOPCT/IB2006/054409 2006-11-23
IB2006054409 2006-11-23

Publications (1)

Publication Number Publication Date
ES2523401T3 true ES2523401T3 (es) 2014-11-25

Family

ID=39316391

Family Applications (2)

Application Number Title Priority Date Filing Date
ES12000613.5T Active ES2523401T3 (es) 2006-11-23 2007-11-22 Intermedios de un nuevo procedimiento para la preparación de derivados de 5-benciliden-2-alquilimino-3- feniltiazolidin-4-ona
ES07849225T Active ES2410793T3 (es) 2006-11-23 2007-11-22 Nuevo procedimiento para la preparación de derivados de 2-imino-tiazolidin-4-ona

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES07849225T Active ES2410793T3 (es) 2006-11-23 2007-11-22 Nuevo procedimiento para la preparación de derivados de 2-imino-tiazolidin-4-ona

Country Status (13)

Country Link
US (1) US8263780B2 (enExample)
EP (2) EP2094676B1 (enExample)
JP (1) JP4669564B2 (enExample)
KR (1) KR101255879B1 (enExample)
CN (2) CN101541772B (enExample)
AU (1) AU2007323042B2 (enExample)
CA (1) CA2669069C (enExample)
DK (2) DK2094676T3 (enExample)
ES (2) ES2523401T3 (enExample)
IL (1) IL198847A (enExample)
MX (1) MX2009005048A (enExample)
TW (1) TWI460166B (enExample)
WO (1) WO2008062376A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
BRPI0416752B8 (pt) 2003-11-21 2021-05-25 Actelion Pharmaceuticals Ltd composição farmacêutica, uso de um ou mais compostos, e, compostos
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
CA2716448A1 (en) 2008-03-17 2009-09-24 Patrick Brossard Dosing regimen for a selective s1p1 receptor agonist
GB0819182D0 (en) 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms
HUE050733T2 (hu) 2012-08-17 2021-01-28 Actelion Pharmaceuticals Ltd Eljárás (2Z,5Z)-5-(3-klór-4-((R)-2,3-dihidroxipropoxi)benzilidén)-2-(pro-pilimino)-3-(O-tolil)tiazolidin-4-on elõállítására és ezen eljárásban alkalmazott köztitermék
HUE057865T2 (hu) 2014-12-11 2022-06-28 Actelion Pharmaceuticals Ltd A poneszimodra, egy szelektív S1P1 receptor agonistára vonatkozó adagolási rend
MA41139B1 (fr) 2014-12-11 2026-02-27 Laboratoires Juvise Pharmaceuticals Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque
JOP20190207A1 (ar) 2017-03-14 2019-09-10 Actelion Pharmaceuticals Ltd تركيبة صيدلانية تشتمل على بونيسيمود
US11220488B2 (en) 2017-09-19 2022-01-11 Teva Pharmaceuticals International Gmbh Crystalline polymorph of Ponesimod
US11013723B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms of a thiazolidinone compound, compositions and methods of use thereof
US11014940B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Thiazolidinone and oxazolidinone compounds and formulations
US11186556B1 (en) 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
US11014897B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof
TW202116742A (zh) * 2019-07-10 2021-05-01 德商拜耳廠股份有限公司 製備2-(苯基亞胺基)-1,3-四氫噻唑-4-酮之方法(二)
EP3997075A1 (de) * 2019-07-10 2022-05-18 Bayer Aktiengesellschaft Verfahren zur herstellung von 2-(phenylimino)-1,3-thiazolidin-4-onen
CA3156298A1 (en) 2019-10-31 2021-05-06 Laetitia POUZOL Combination of a cxcr7 antagonist with an s1p1 receptor modulator
KR20200019639A (ko) 2020-01-30 2020-02-24 전대연 만남의 스마트 도착시스템
JP2023513623A (ja) * 2020-02-18 2023-03-31 バイエル・アクチエンゲゼルシヤフト ２－（フェニルイミノ）－３－アルキル－１，３－チアゾリジン－４－オン類の製造方法
US20240368094A1 (en) 2021-08-17 2024-11-07 Teva Czech Industries S.R.O Polymorphs of ponesimod
EP4212156A1 (en) 2022-01-13 2023-07-19 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
WO2023152691A1 (en) * 2022-02-10 2023-08-17 Metrochem Api Pvt Ltd Process for the preparation of ponesimod and its intermediates thereof
CN117924210B (zh) * 2024-01-22 2026-04-03 赣南师范大学 一种2-亚氨基噻唑烷-4-酮类化合物的制备方法

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US3077402A (en) * 1954-12-06 1963-02-12 Polaroid Corp Photographic color processes, products, and compositions
NL270002A (enExample) * 1960-10-08
OA03835A (fr) * 1970-07-17 1971-12-24 Rhone Poulenc Sa Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent.
CA2080917C (en) 1990-04-27 2001-06-12 Reijo Baeckstroem New pharmacologically active catechol derivatives
TW221689B (enExample) * 1991-08-27 1994-03-11 Otsuka Pharma Co Ltd
ATE212018T1 (de) * 1993-02-26 2002-02-15 Otsuka Pharma Co Ltd Thiazole oder imidazole derivate als maillard reaktion inhibitoren
KR960022486A (ko) 1994-12-29 1996-07-18 김준웅 신규 티아졸리딘-4-온 유도체
US6353006B1 (en) * 1999-01-14 2002-03-05 Bayer Corporation Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
EP1219612B1 (en) 1999-09-14 2008-04-23 Shionogi & Co., Ltd. 2-imino-1,3-thiazine derivatives
PT1142885E (pt) * 1999-11-12 2007-02-28 Fujimoto Brothers Co Ltd Derivados de 2-(n-cianoimino)tiazolidin-4-ona
US20050019825A9 (en) * 2002-03-15 2005-01-27 Qing Dong Common ligand mimics: pseudothiohydantoins
MXPA05000453A (es) 2002-07-10 2005-03-23 Applied Research Systems Derivados de benceno fusionados a azolidinona-vinilo.
GB0217152D0 (en) 2002-07-24 2002-09-04 Novartis Ag Organic compounds
KR20050085115A (ko) * 2002-11-22 2005-08-29 스미스클라인 비참 코포레이션 신규 화합물
US20040167192A1 (en) * 2003-01-16 2004-08-26 David Solow-Cordero Methods of treating conditions associated with an Edg-7 receptor
BRPI0416752B8 (pt) * 2003-11-21 2021-05-25 Actelion Pharmaceuticals Ltd composição farmacêutica, uso de um ou mais compostos, e, compostos
US20070249599A1 (en) * 2004-02-25 2007-10-25 Duffy Kevin J Novel Chemical Compounds
WO2006094233A1 (en) * 2005-03-03 2006-09-08 Sirtris Pharmaceuticals, Inc. N,n'-dicyclic isothiourea sirtuin modulators
CA2716448A1 (en) * 2008-03-17 2009-09-24 Patrick Brossard Dosing regimen for a selective s1p1 receptor agonist
GB0819182D0 (en) * 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms

Also Published As

Publication number Publication date
WO2008062376A2 (en) 2008-05-29
EP2094676A2 (en) 2009-09-02
EP2489662B1 (en) 2014-08-06
CN103087004A (zh) 2013-05-08
US8263780B2 (en) 2012-09-11
TW200831474A (en) 2008-08-01
EP2094676B1 (en) 2013-04-10
JP4669564B2 (ja) 2011-04-13
ES2410793T3 (es) 2013-07-03
IL198847A0 (en) 2010-02-17
KR20090081009A (ko) 2009-07-27
IL198847A (en) 2015-07-30
CN101541772A (zh) 2009-09-23
KR101255879B1 (ko) 2013-04-17
AU2007323042A1 (en) 2008-05-29
US20110201821A2 (en) 2011-08-18
JP2010510976A (ja) 2010-04-08
CN101541772B (zh) 2013-04-17
CA2669069A1 (en) 2008-05-29
DK2094676T3 (da) 2013-06-10
WO2008062376A3 (en) 2008-07-10
CA2669069C (en) 2015-02-17
BRPI0718986A2 (pt) 2014-02-11
US20100317867A1 (en) 2010-12-16
AU2007323042B2 (en) 2012-12-20
MX2009005048A (es) 2009-05-25
EP2489662A1 (en) 2012-08-22
DK2489662T3 (da) 2014-10-20
TWI460166B (zh) 2014-11-11

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