ES2521675T3 - Identificación y uso de [2Fe-2S]-dihidroxi-ácido deshidratasas bacterianas - Google Patents
Identificación y uso de [2Fe-2S]-dihidroxi-ácido deshidratasas bacterianas Download PDFInfo
- Publication number
- ES2521675T3 ES2521675T3 ES09793126.5T ES09793126T ES2521675T3 ES 2521675 T3 ES2521675 T3 ES 2521675T3 ES 09793126 T ES09793126 T ES 09793126T ES 2521675 T3 ES2521675 T3 ES 2521675T3
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- dhad
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Links
- 102000004867 Hydro-Lyases Human genes 0.000 title abstract 2
- 108090001042 Hydro-Lyases Proteins 0.000 title abstract 2
- 101100452478 Arabidopsis thaliana DHAD gene Proteins 0.000 abstract 6
- KKZJGLLVHKMTCM-UHFFFAOYSA-N mitoxantrone Chemical compound O=C1C2=C(O)C=CC(O)=C2C(=O)C2=C1C(NCCNCCO)=CC=C2NCCNCCO KKZJGLLVHKMTCM-UHFFFAOYSA-N 0.000 abstract 6
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 235000018102 proteins Nutrition 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Chemical group OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 2
- 241000194019 Streptococcus mutans Species 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 229940024606 amino acid Drugs 0.000 abstract 2
- 235000009582 asparagine Nutrition 0.000 abstract 2
- 229960001230 asparagine Drugs 0.000 abstract 2
- 125000000613 asparagine group Chemical group N[C@@H](CC(N)=O)C(=O)* 0.000 abstract 2
- 239000004475 Arginine Substances 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical group NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 abstract 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001413 amino acids Chemical group 0.000 abstract 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
- 235000003704 aspartic acid Nutrition 0.000 abstract 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N aspartic acid group Chemical group N[C@@H](CC(=O)O)C(=O)O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 1
- 235000018417 cysteine Nutrition 0.000 abstract 1
- 125000000151 cysteine group Chemical class N[C@@H](CS)C(=O)* 0.000 abstract 1
- -1 dihydroxy amino Chemical group 0.000 abstract 1
- 125000001909 leucine group Chemical group [H]N(*)C(C(*)=O)C([H])([H])C(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01009—Dihydroxy-acid dehydratase (4.2.1.9), i.e. acetohydroxyacid dehydratase
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Theoretical Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10079208P | 2008-09-29 | 2008-09-29 | |
| US100792P | 2008-09-29 | ||
| PCT/US2009/058827 WO2010037112A1 (en) | 2008-09-29 | 2009-09-29 | IDENTIFICATION AND USE OF BACTERIAL [2Fe-2S] DIHYDROXY-ACID DEHYDRATASES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2521675T3 true ES2521675T3 (es) | 2014-11-13 |
Family
ID=41402186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09793126.5T Active ES2521675T3 (es) | 2008-09-29 | 2009-09-29 | Identificación y uso de [2Fe-2S]-dihidroxi-ácido deshidratasas bacterianas |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20100081154A1 (enExample) |
| EP (2) | EP2821484B1 (enExample) |
| JP (1) | JP5846912B2 (enExample) |
| KR (1) | KR101659101B1 (enExample) |
| CN (1) | CN102186973B (enExample) |
| AU (1) | AU2009296225B2 (enExample) |
| BR (1) | BRPI0913682A2 (enExample) |
| CA (1) | CA2735690A1 (enExample) |
| ES (1) | ES2521675T3 (enExample) |
| MX (1) | MX2011003238A (enExample) |
| NZ (1) | NZ591244A (enExample) |
| WO (1) | WO2010037112A1 (enExample) |
| ZA (2) | ZA201101367B (enExample) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8956850B2 (en) | 2008-06-05 | 2015-02-17 | Butamax Advanced Biofuels Llc | Enhanced pyruvate to acetolactate conversion in yeast |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| NZ579780A (en) | 2007-04-18 | 2012-07-27 | Butamax Advanced Biofuels Llc | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| US20160222370A1 (en) * | 2008-09-29 | 2016-08-04 | Butamax Advanced Biofuels Llc | Recombinant Yeast Host Cell With Fe-S Cluster Proteins And Methods Of Using Thereof |
| CA2735948A1 (en) * | 2008-09-29 | 2011-04-01 | Butamaxtm Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
| CA2735690A1 (en) | 2008-09-29 | 2010-04-01 | Dennis Flint | Identification and use of bacterial [2fe-2s] dihydroxy-acid dehydratases |
| AU2009296218A1 (en) * | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
| CN102186983A (zh) | 2008-09-29 | 2011-09-14 | 布特马斯先进生物燃料有限责任公司 | 酵母中提高的异源Fe-S酶活性 |
| US8465964B2 (en) | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
| US8614085B2 (en) * | 2009-02-27 | 2013-12-24 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving a multidrug efflux pump gene |
| JP2012523245A (ja) | 2009-04-13 | 2012-10-04 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 抽出発酵を用いてブタノールを生成するための方法 |
| CA2770842A1 (en) * | 2009-08-12 | 2011-02-17 | Gevo, Inc. | Cytosolic isobutanol pathway localization for the production of isobutanol |
| BR112012006939A2 (pt) * | 2009-09-29 | 2015-09-08 | Butamax Tm Advanced Biofuels | célula hospedeira de produção de levedura recombinante e método para a produção de um produto selecionado do grupo que consiste em 2,3-butanodiol, isobutanol, 2-butanol, 1-butanol, 2-butanona, valina, leucina, ácido lático, ácido málico, álcool, isoampilico e isoprenoides |
| CA2775892A1 (en) | 2009-09-29 | 2011-04-07 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes |
| US20110195505A1 (en) * | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
| NZ599414A (en) * | 2009-11-23 | 2014-08-29 | Butamax Tm Advanced Biofuels | Method for producing butanol using extractive fermentation with electrolyte addition |
| CA2779460A1 (en) * | 2009-11-23 | 2011-05-26 | Butamax(Tm) Advanced Biofuels Llc | Method for producing butanol using extractive fermentation with osmolyte addition |
| GB2487889B (en) | 2009-11-24 | 2012-12-19 | Gevo Inc | Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids |
| US8637289B2 (en) | 2009-12-29 | 2014-01-28 | Butamax(Tm) Advanced Biofuels Llc | Expression of hexose kinase in recombinant host cells |
| MX2012007583A (es) | 2009-12-29 | 2012-07-30 | Butamax Tm Advanced Biofuels | Alcohol deshidrogenasas (adh) utiles para la produccion fermentativa de alcoholes alquilicos de cadena corta. |
| CN102782119B (zh) | 2010-02-17 | 2016-03-16 | 布特马斯先进生物燃料有限责任公司 | 改善需Fe-S簇蛋白质的活性 |
| KR102032075B1 (ko) * | 2010-05-24 | 2019-10-14 | 질레코 인코포레이티드 | 바이오매스의 가공처리 |
| AU2011268326B2 (en) | 2010-06-17 | 2015-02-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast production culture for the production of butanol |
| US9012190B2 (en) | 2011-06-15 | 2015-04-21 | Butamax Advanced Biofuels Llc | Use of thiamine and nicotine adenine dinucleotide for butanol production |
| US9040263B2 (en) | 2010-07-28 | 2015-05-26 | Butamax Advanced Biofuels Llc | Production of alcohol esters and in situ product removal during alcohol fermentation |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| KR20130032897A (ko) | 2010-06-18 | 2013-04-02 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | 알코올 발효 시의 알코올 에스테르의 생성 및 원위치에서의 생성물 제거 |
| CN105950673A (zh) | 2010-06-18 | 2016-09-21 | 布特马斯先进生物燃料有限责任公司 | 在提取发酵中用于醇移除的来源于油的提取溶剂 |
| NZ707800A (en) | 2010-09-07 | 2016-09-30 | Butamax Tm Advanced Biofuels | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| US20130040340A1 (en) | 2011-02-07 | 2013-02-14 | E. I. Du Pont De Nemours And Company | Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms |
| US8759044B2 (en) | 2011-03-23 | 2014-06-24 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
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| EP2689014B1 (en) | 2011-03-24 | 2019-04-24 | Butamax (TM) Advanced Biofuels LLC | Host cells and methods for production of isobutanol |
| CA2837722A1 (en) | 2011-06-17 | 2012-12-20 | Butamax Advanced Biofuels Llc | Co-products from biofuel production processes and methods of making |
| CN105473726B (zh) | 2011-07-28 | 2021-03-12 | 布特马斯先进生物燃料有限责任公司 | 酮异戊酸脱羧酶及其使用方法 |
| WO2013043801A1 (en) * | 2011-09-20 | 2013-03-28 | Gevo, Inc. | High-performance dihydroxy acid dehydratases |
| AU2012347687A1 (en) | 2011-12-09 | 2014-05-29 | Butamax Advanced Biofuels Llc | Process to remove product alcohols from fermentation broth by multistep flash evaporation |
| US9909148B2 (en) | 2011-12-30 | 2018-03-06 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
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| BR112015003701A2 (pt) | 2012-08-22 | 2017-12-12 | Butamax Advanced Biofuels Llc | células hospedeiras recombinantes, método para aprimoramento, processo para a produção de um álcool, polinucleotídeo isolado, cassete de expressão e composição |
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| EP2900825A1 (en) | 2012-09-28 | 2015-08-05 | Butamax Advanced Biofuels LLC | Production of fermentation products |
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| CA2957920A1 (en) | 2014-08-11 | 2016-02-18 | Butamax Advanced Biofuels Llc | Yeast preparations and methods of making the same |
| WO2018157942A1 (en) | 2017-03-03 | 2018-09-07 | Nmr - Bio | Cell-free synthesis of isotopic labelled proteins from amino-acids precursors |
| CN111893083A (zh) * | 2019-05-05 | 2020-11-06 | 中国科学院上海高等研究院 | 改造的克雷伯氏属细菌及其生产2,3-二羟基异戊酸的应用 |
| DE102022119024A1 (de) * | 2022-07-28 | 2024-02-08 | INM - Leibniz-Institut für Neue Materialien gemeinnützige Gesellschaft mit beschränkter Haftung | Neuartige genetische Werkzeuge |
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| EP1887081A2 (en) * | 1999-02-25 | 2008-02-13 | Ceres Incorporated | DNA Sequences |
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| EP1948814B1 (en) | 2005-10-26 | 2018-11-21 | Butamax (TM) Advanced Biofuels LLC | Fermentive production of four carbon alcohols |
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| DE102008010121B4 (de) | 2008-02-20 | 2013-11-21 | Butalco Gmbh | Fermentative Produktion von Isobutanol mit Hefe |
| AU2009256148B2 (en) * | 2008-06-04 | 2014-11-27 | Butamax(Tm) Advanced Biofuels Llc | A method for producing butanol using two-phase extractive fermentation |
| BRPI0913680A2 (pt) | 2008-09-29 | 2019-09-24 | Butamax Advanced Biofuels Llc | "célula bacteriana ácido-láctica, método para aumentar a atividade de um polipeptídeo dihidroxi-ácido desidratase heterólogo em uma célula bacteriana ácido-láctica e método de produção de insobutanol" |
| CA2735690A1 (en) | 2008-09-29 | 2010-04-01 | Dennis Flint | Identification and use of bacterial [2fe-2s] dihydroxy-acid dehydratases |
| CA2735948A1 (en) | 2008-09-29 | 2011-04-01 | Butamaxtm Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
| AU2009296218A1 (en) | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria |
| CN102186983A (zh) | 2008-09-29 | 2011-09-14 | 布特马斯先进生物燃料有限责任公司 | 酵母中提高的异源Fe-S酶活性 |
| US8828694B2 (en) * | 2008-11-13 | 2014-09-09 | Butamax Advanced Biofuels Llc | Production of isobutanol in yeast mitochondria |
| CA2770842A1 (en) * | 2009-08-12 | 2011-02-17 | Gevo, Inc. | Cytosolic isobutanol pathway localization for the production of isobutanol |
| BR112012006939A2 (pt) * | 2009-09-29 | 2015-09-08 | Butamax Tm Advanced Biofuels | célula hospedeira de produção de levedura recombinante e método para a produção de um produto selecionado do grupo que consiste em 2,3-butanodiol, isobutanol, 2-butanol, 1-butanol, 2-butanona, valina, leucina, ácido lático, ácido málico, álcool, isoampilico e isoprenoides |
| CA2775892A1 (en) * | 2009-09-29 | 2011-04-07 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes |
| CA2779460A1 (en) * | 2009-11-23 | 2011-05-26 | Butamax(Tm) Advanced Biofuels Llc | Method for producing butanol using extractive fermentation with osmolyte addition |
| NZ599414A (en) * | 2009-11-23 | 2014-08-29 | Butamax Tm Advanced Biofuels | Method for producing butanol using extractive fermentation with electrolyte addition |
-
2009
- 2009-09-29 CA CA2735690A patent/CA2735690A1/en not_active Abandoned
- 2009-09-29 KR KR1020117009692A patent/KR101659101B1/ko not_active Expired - Fee Related
- 2009-09-29 US US12/569,636 patent/US20100081154A1/en not_active Abandoned
- 2009-09-29 MX MX2011003238A patent/MX2011003238A/es not_active Application Discontinuation
- 2009-09-29 EP EP14180626.5A patent/EP2821484B1/en active Active
- 2009-09-29 WO PCT/US2009/058827 patent/WO2010037112A1/en not_active Ceased
- 2009-09-29 ES ES09793126.5T patent/ES2521675T3/es active Active
- 2009-09-29 CN CN200980138542.2A patent/CN102186973B/zh not_active Expired - Fee Related
- 2009-09-29 JP JP2011529364A patent/JP5846912B2/ja active Active
- 2009-09-29 EP EP09793126.5A patent/EP2337851B1/en active Active
- 2009-09-29 NZ NZ591244A patent/NZ591244A/xx not_active IP Right Cessation
- 2009-09-29 BR BRPI0913682-7A patent/BRPI0913682A2/pt not_active Application Discontinuation
- 2009-09-29 AU AU2009296225A patent/AU2009296225B2/en active Active
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2011
- 2011-02-21 ZA ZA2011/01367A patent/ZA201101367B/en unknown
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2013
- 2013-03-15 US US13/838,508 patent/US8951937B2/en active Active
- 2013-03-15 US US13/838,570 patent/US20140051137A1/en not_active Abandoned
- 2013-12-20 ZA ZA2013/09658A patent/ZA201309658B/en unknown
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| Publication number | Publication date |
|---|---|
| ZA201309658B (en) | 2016-06-29 |
| NZ591244A (en) | 2013-03-28 |
| EP2337851A1 (en) | 2011-06-29 |
| KR20110063575A (ko) | 2011-06-10 |
| CN102186973B (zh) | 2017-08-15 |
| CN102186973A (zh) | 2011-09-14 |
| AU2009296225A1 (en) | 2010-04-01 |
| ZA201101367B (en) | 2014-03-26 |
| AU2009296225B2 (en) | 2015-09-17 |
| KR101659101B1 (ko) | 2016-09-22 |
| JP2012503993A (ja) | 2012-02-16 |
| JP5846912B2 (ja) | 2016-01-20 |
| US20100081154A1 (en) | 2010-04-01 |
| BRPI0913682A2 (pt) | 2020-08-11 |
| US8951937B2 (en) | 2015-02-10 |
| US20140051137A1 (en) | 2014-02-20 |
| EP2821484A1 (en) | 2015-01-07 |
| MX2011003238A (es) | 2011-04-28 |
| US20140030776A1 (en) | 2014-01-30 |
| CA2735690A1 (en) | 2010-04-01 |
| EP2821484B1 (en) | 2016-06-29 |
| WO2010037112A1 (en) | 2010-04-01 |
| EP2337851B1 (en) | 2014-08-13 |
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