ES2521515T3 - Compuestos cíclicos peptidomiméticos con giro beta para tratar el ojo seco - Google Patents
Compuestos cíclicos peptidomiméticos con giro beta para tratar el ojo seco Download PDFInfo
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- ES2521515T3 ES2521515T3 ES09726969.0T ES09726969T ES2521515T3 ES 2521515 T3 ES2521515 T3 ES 2521515T3 ES 09726969 T ES09726969 T ES 09726969T ES 2521515 T3 ES2521515 T3 ES 2521515T3
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- dry eye
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- C—CHEMISTRY; METALLURGY
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Landscapes
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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Applications Claiming Priority (5)
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| US123036P | 2008-04-04 | ||
| US20887309P | 2009-02-27 | 2009-02-27 | |
| US208873P | 2009-02-27 | ||
| PCT/US2009/002121 WO2009123761A1 (en) | 2008-04-04 | 2009-04-03 | Beta-turn peptidomimetic cyclic compounds for treating dry eye |
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| ES2521515T3 true ES2521515T3 (es) | 2014-11-12 |
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| CN (1) | CN102046166B (OSRAM) |
| AU (1) | AU2009232352B2 (OSRAM) |
| CA (1) | CA2720141C (OSRAM) |
| ES (1) | ES2521515T3 (OSRAM) |
| WO (1) | WO2009123761A1 (OSRAM) |
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| KR101565185B1 (ko) * | 2008-04-04 | 2015-11-02 | 미메토젠 파르마슈티칼스 인크. | 건안증을 치료하기 위한 베타-턴 펩티도미메틱 환상 화합물 |
| KR102061382B1 (ko) * | 2012-06-22 | 2019-12-31 | 미메토젠 파르마슈티칼스 인크. | 베타-턴 펩티도미메틱 환상 화합물의 합성 |
| KR20150004652A (ko) | 2013-07-03 | 2015-01-13 | 삼성디스플레이 주식회사 | 표시 패널, 이를 포함하는 표시 장치 및 이를 이용하는 영상 표시 방법 |
| JP6267003B2 (ja) * | 2014-02-27 | 2018-01-24 | 参天製薬株式会社 | ジクアホソルまたはその塩およびレバミピドまたはその塩を組み合わせたことを特徴とする涙液分泌促進剤 |
| CN107106325B (zh) | 2015-01-12 | 2021-05-25 | 科达莱昂治疗公司 | 微滴递送设备和方法 |
| AU2016246060B2 (en) | 2015-04-10 | 2020-10-22 | Bausch + Lomb Ireland Limited | Piezoelectric dispenser with replaceable ampoule |
| JP6801835B2 (ja) | 2015-07-09 | 2020-12-16 | ミメトゲン ファーマシュウティカルズ インコーポレイテッドＭｉｍｅｔｏｇｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | β−ターンペプチド模倣環状塩の液相合成及び結晶化 |
| KR101718733B1 (ko) | 2015-08-21 | 2017-03-22 | 국제약품 주식회사 | 레바미피드의 가용화 방법 및 이에 의해 제조된 안구건조증 치료용 액제 |
| JP2019507193A (ja) | 2016-03-04 | 2019-03-14 | ジェームズ・エム・ライナーソン | 細菌のバイオフィルム形成を阻止又は妨害することによって眼障害を治療する方法 |
| CA3039106A1 (en) | 2017-01-20 | 2018-07-26 | Kedalion Therapeutics, Inc. | Piezoelectric fluid dispenser |
| AU2018380433B2 (en) | 2017-12-08 | 2024-10-10 | Bausch + Lomb Ireland Limited | Fluid delivery alignment system |
| CN110092799B (zh) * | 2018-01-29 | 2021-11-12 | 广州丹康医药生物有限公司 | 一种环状化合物、其制备方法和应用 |
| US12350194B1 (en) | 2018-04-12 | 2025-07-08 | Bausch + Lomb Ireland Limited | Topical ocular delivery of fluids with controlled mass dosing and wireless communication |
| US20190314197A1 (en) | 2018-04-12 | 2019-10-17 | Kedalion Therapeutics, Inc. | Topical Ocular Delivery Methods and Devices for Use in the Same |
| WO2020010116A1 (en) | 2018-07-03 | 2020-01-09 | Kedalion Therapeutics, Inc. | Topical ocular delivery devices and methods for using the same |
| US12097145B2 (en) | 2019-03-06 | 2024-09-24 | Bausch + Lomb Ireland Limited | Vented multi-dose ocular fluid delivery system |
| US11679028B2 (en) | 2019-03-06 | 2023-06-20 | Novartis Ag | Multi-dose ocular fluid delivery system |
| US12496218B1 (en) | 2019-11-12 | 2025-12-16 | Bausch + Lomb Ireland Limited | Fractionated topical ocular drug delivery methods and devices for use in the same |
| US11938057B2 (en) | 2020-04-17 | 2024-03-26 | Bausch + Lomb Ireland Limited | Hydrodynamically actuated preservative free dispensing system |
| IL297215A (en) | 2020-04-17 | 2022-12-01 | Kedallon Therapeutics Inc | A hydrodynamically activated preservative free distribution system |
| WO2021212038A1 (en) | 2020-04-17 | 2021-10-21 | Kedalion Therapeutics, Inc. | Hydrodynamically actuated preservative free dispensing system having a collapsible liquid reservoir |
| US12290472B2 (en) | 2020-04-17 | 2025-05-06 | Bausch + Lomb Ireland Limited | Hydrodynamically actuated preservative free dispensing system |
| JP2024520670A (ja) * | 2021-06-02 | 2024-05-24 | ザ テキサス エーアンドエム ユニヴァーシティ システム | Ｔｒｋ受容体の選択的小分子アゴニスト及び部分アゴニスト |
| WO2023069255A1 (en) * | 2021-10-20 | 2023-04-27 | Stealth Biotherapeutics Inc. | Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions |
| EP4419123A1 (en) * | 2021-10-20 | 2024-08-28 | Stealth BioTherapeutics Inc. | Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions |
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| GB8917217D0 (en) * | 1989-07-27 | 1989-09-13 | Smith & Nephew | Ophthalmic compositions |
| US5545617A (en) * | 1993-11-12 | 1996-08-13 | The Schepens Eye Research Institute, Inc. | Therapeutic regulation of abnormal conjunctival goblet cell mucous secretion |
| US6238888B1 (en) * | 1997-12-22 | 2001-05-29 | Human Genone Sciences, Inc. | Keratinocyte growth factor-2 formulations |
| JP2001064198A (ja) | 1999-08-24 | 2001-03-13 | Teika Seiyaku Kk | 角膜疾患治療剤 |
| WO2001052843A1 (en) * | 2000-01-18 | 2001-07-26 | Mcgill University | β-TURN PEPTIDOMIMETIC CYCLIC COMPOUNDS |
| DE602005012812D1 (de) | 2005-06-13 | 2009-04-02 | Primm Srl | Heterodimere Peptide mit NGF Aktivität und deren Verwendung zur Behandlung von neurodegenerativen Krankheiten |
| EP1921087A1 (en) | 2006-11-10 | 2008-05-14 | Primm S.R.L. | Process for the preparation of cyclic peptides |
| CN101657212B (zh) * | 2006-12-05 | 2014-03-19 | 皇家学习促进会/麦吉尔大学 | Trk受体调节剂的使用方法 |
| KR101565185B1 (ko) * | 2008-04-04 | 2015-11-02 | 미메토젠 파르마슈티칼스 인크. | 건안증을 치료하기 위한 베타-턴 펩티도미메틱 환상 화합물 |
| ES2512717T3 (es) * | 2009-02-27 | 2014-10-24 | Mimetogen Pharmaceuticals Inc. | Compuestos cíclicos peptidomiméticos para el tratamiento de la retinitis pigmentosa |
| KR102061382B1 (ko) * | 2012-06-22 | 2019-12-31 | 미메토젠 파르마슈티칼스 인크. | 베타-턴 펩티도미메틱 환상 화합물의 합성 |
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2009
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- 2009-04-03 WO PCT/US2009/002121 patent/WO2009123761A1/en not_active Ceased
- 2009-04-03 CA CA2720141A patent/CA2720141C/en active Active
- 2009-04-03 ES ES09726969.0T patent/ES2521515T3/es active Active
- 2009-04-03 US US12/935,217 patent/US8293713B2/en active Active
- 2009-04-03 CN CN2009801190689A patent/CN102046166B/zh active Active
- 2009-04-03 JP JP2011502992A patent/JP5480242B2/ja active Active
- 2009-04-03 EP EP09726969.0A patent/EP2271337B1/en active Active
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2012
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2014
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- 2014-05-29 US US14/290,845 patent/US9156882B2/en active Active
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2015
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Also Published As
| Publication number | Publication date |
|---|---|
| CN102046166A (zh) | 2011-05-04 |
| JP5480242B2 (ja) | 2014-04-23 |
| HK1152898A1 (en) | 2012-03-16 |
| JP2011516477A (ja) | 2011-05-26 |
| CA2720141C (en) | 2014-01-28 |
| US9156882B2 (en) | 2015-10-13 |
| AU2009232352A1 (en) | 2009-10-08 |
| US9707267B2 (en) | 2017-07-18 |
| US8748391B2 (en) | 2014-06-10 |
| JP2014080447A (ja) | 2014-05-08 |
| US20110105410A1 (en) | 2011-05-05 |
| EP2271337B1 (en) | 2014-09-03 |
| EP2271337A1 (en) | 2011-01-12 |
| US20160082072A1 (en) | 2016-03-24 |
| KR101565185B1 (ko) | 2015-11-02 |
| US8293713B2 (en) | 2012-10-23 |
| WO2009123761A1 (en) | 2009-10-08 |
| KR20110010712A (ko) | 2011-02-07 |
| US20140274910A1 (en) | 2014-09-18 |
| AU2009232352B2 (en) | 2013-09-05 |
| US20120322747A1 (en) | 2012-12-20 |
| CA2720141A1 (en) | 2009-10-08 |
| JP5870348B2 (ja) | 2016-02-24 |
| CN102046166B (zh) | 2012-10-17 |
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